• Journal of radiological science and technology
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• v.46 no.4
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• pp.303-313
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• 2023

This study aimed to investigate the relevance of cardiovascular disease risk factors AI and AIP, divided into three groups, among 300 individuals who underwent health checkups at the hospital. Various variables such as Age, Sex, BMI, WC, TC, TG, HDL-C, LDL-C, FBS, HbA1C, SBP, DBP, HR, AI (TC/HDL-C), and AIP (log(TG/HDL-C)) were analyzed using statistical methods including frequency analysis, cross-tabulation, one-way ANOVA, Pearson's correlation analysis, and multiple linear regression analysis. The cross-analysis based on cardiovascular disease risk criteria revealed that men and individuals in their 50s had higher cardiovascular disease risk based on AI and AIP. Significant differences were observed in TG, TC, HDL-C, LDL-C, SBP, DBP, AI (TC/HDL-C), and AIP (log(TG/HDL-C)) according to AI criteria. For the AIP criteria, TG, TC, HDL-C, FBS, HbA1C, HR, AI (TC/HDL-C), and AIP (log(TG/HDL-C)) were identified as cardiovascular disease risk factors. FBS and HbA1c showed the highest positive correlation In the correlation analysis, followed by TC and LDL-C. The lowest positive correlation was observed between LDL-C and DBP. In terms of negative correlation, HDL-C and AI had the highest negative correlation, while LDL-C and TG showed the lowest negative correlation. Multiple regression analysis indicated that the AI and AIP risk criteria had explanatory powers of 73.6% and 72.5%, respectively. HDL-C had the greatest negative effect on the AI risk criterion, while TG had the most significant influence on the AIP risk criterion. In conclusion, while other serological variables are important, managing HDL-C and TG levels may help reduce the risk of cardiovascular disease.

• Journal of the Korean Dietetic Association
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• v.11 no.3
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• pp.365-374
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• 2005

This study was conducted to compare the validity of obese index among body mass index(BMI), waist to hip ratio(WHR), and waist circumference(WC) and to determine which is the best in relation to cardiovascular risk factors of middle aged Korean(40-64yr).Data from the 1998 Korean Health and Nutrition Survey were used(N=3380). Anthropometric indices and cardiovascular risk factors were measured. Chi-square test, analysis of variance following duncan's multiple range test, partial correlation analysis, and Receiver Operator characteristic(ROC) curves were used in the analysis. There was a significant increasing trend in WHR, systolic blood pressure(SBP), high density lipoprotein cholesterol(HDL), and fasting blood sugar(FBS) with age categories of male and in BMI, WC, WHR, diastolic blood pressure(DBP), SBP, total cholesterol(TC), low density lipoprotein cholesterol(LDL), triglycerol(TG), and FBS with those of female. Specially female had the characteristics of upper body fat and systolic blood pressure risk(p<0.05). Proportions of subjects with lifestyle factors related to cardiovascular risk in overweight or upper body fat group were higher than that of normal group. Higher proportions of subjects were practiced exercise in upper body fat group of male than in other groups. Among 7 cardiovascular risk factors in partial correlation analysis, BMI had the highest correlation coefficient in 6 risk factors in male, whereas WC in 4 risk factors in female. Mean of each obese index according to cardiovascular risk groups except smoker was higher than that of normal(p<0.05). These trends were shown in upper body fat group and female. In ROC analysis of 12 risk factors and health conditions, the largest area under curve among obese indices for risk factors were BMI in male and WHR in female. The optimal cutoff values of each index(BMI: WHR: WC) for one or more cardiovascular risk factors were 23.13: 0.89: 85.35 in male and 23.57: 0.84: 78.35 in female. The results showed that cardiovascular risk factors were prevalent in middle aged Koreans within normal limits of obese indices like another Asians. For the identification of cardiovascular risk factors of middle aged Koreans, BMI for men and WHR for women are appropriate indices. But it is recommended that BMI, WHR, and WC, all three indices should be considered, when using these indices.

• Journal of Preventive Medicine and Public Health
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• v.30 no.2 s.57
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• pp.327-341
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• 1997

It is a well known fact that obesity is an important cause of cardiovascular disease, emphasized by many studies. Recently, cardiovascular diseaase has been found to correlate not only to the extent of obesity, but also the fat distribution of the individual; especially, focusing on obesity of the abdomen. Unfortunately, the proposed indices for abdominal obesity are numerous, and the results vary according to the index chosen. Three-hundred and twelve bus drivers in November, 1995, were chosen as subjects of this study. The author chose to measure serum lipid levels, fasting blood sugar levels and blood pressure, that are thought to be important risk factors of cardiovascular diseases. Obesity indices were calculated using anthropometric measurements. We were able to evaluate the significance of obesity indices by examining correlations between these indices and the risk factors of cardiovascular disease. The results obtained were as follows: 1. The abdominal obesity indices and risk factors of cardiovascular disease, the levels of total cholesterol in the serum, fasting blood sugar levels, and diastolic blood pressure, increased significantly according to age. 2. There was a significant difference in the abdominal obesity indices according to drinking and smoking habits controlled for age. Among the risk factors of cardiovascular disease, triglyceride and diastolic pressures had significant differences according to the presence or absence of a drinking history controlled for age. 3. Although all obesity indices showed significant correlations, the weakest correlation was between BMI and abdominal diameter index and the strongest correlation was between sagittal diameter and sagittal diameter matched for height. 4. There was a negative correlation between HDL-cholesterol and obesity indices. The weakest correlation was between fasting blood sugar levels and both SD and SDH showed correlations with the risk factors. 5. There was a significant correlation between SD and total cholesterol in the serum and fasting blood sugars controlled for age, drinking, and BMI. 6. After categorizing the subjects into 2 separate age groups at the 40 year mark, in the less than 40 you old age group, controlled for drinking and BMI, the results of comparitive studies have shown correlations between total cholesterol serum levels and waist-hip ratio, conicity-index, and SD. There were correlations between fasting blood sugar levels and SD, ADI, and SDH. There were no correlations between obesity indices and both total cholesterol serum levels and fasting blood sugar levels in the greater than 40 year old age group. There were significant correlations between abdominal obesity indices and total serum cholesterol or fasting blood sugar levels in the less than 40 year old age group, but no correlations in the age group over 40. These correlated factors between abdominal obesity and cardiovascular disease are assumed to exist in Korea as well. Furthermore, in this study a high correlation was found between SD, SDH and the risk factors of cardiovascular disease. Even when controlled for age, drinking, smoking, and BMI, the correlations between risk factors of cardiovascular disease and these indices exist. Therefore, the obesity indices, SD and SDH may prove to be important prognostic indicators or risk factors of cardiovascular disease.

• The Journal of the Society of Stroke on Korean Medicine
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• v.6 no.1
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• pp.25-32
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• 2005

Background and purpose: Arterial stiffness is an important, independent determinant of cardiovascular risk. Pulse wave velocity (PWV) has been used as a valuable index of arterial stiffness and as a surrogate marker for atherosclerosis. The Framingham risk score was developed using categorized risk factors to predict the 10 year absolute risk of developing coronary heart disease (CHD). This algorithm is established using recommended guidelines for blood pressure, total cholesterol, and high density lipoprotein cholesterol in addition to age, smoking history and history of diabetes. Tongxinluo(TXL) has been shown to have anti hyperlipidemic activity and anti atherogenic effects. To determine its efficacy and safety, we examined whether TXL improves PWV, ABI, Framingham score, blood pressure, and lipid profile in high risk group of cardiovascular diseases. Subjects and methods: 49 subjects with the high risk of cardiovascular diseases were recruited. Subjects were administered TXL with the dose of 1110mg three times a day for 8 weeks. baPWV, ABI, Framingham risk score, Blood pressure and serum lipid profile were assessed at baseline and after 4 and 8weeks. Results: Total cholesterol, LDL cholesterol, triglyceride, total lipid and phospolipid significantly decreased after 4 weeks of medication. Total cholesterol, total lipid and phospolipid significantly decreased after 8 weeks of medication. There were no significant changes in Framingham risk scores, ABI, PWV and blood pressure. On safety assessment, there were no adverse effects, hepatic or renal toxicity. Conclusion: We suggest that TXL is a safe and useful herbal medicine for hyperlipidemia and as for anti-atherognic effects, further research would be necessary.

• Journal of Korean Medicine for Obesity Research
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• v.4 no.1
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• pp.33-43
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• 2004

Background: Recently obesity has become a social problem in all over the world including Korea. It is known that obesity is closely related with cardiovascular disease. Many studies are carrying out in the relation between several obesity indices, such as body mass index(BMI), waist-circumference(WC), body fat percent and risk factors of cardiovascular disease. Objective: This study was done in order to investigate correlation of obesity and cardiovascular risk factors. Method: We gathered totally 138 subjects who have taken health screening test in university hospital. With the exception of 40 abnormal cases on current illness and laboratory study, 98 healthy cases were analysed. We divided the groups as normal, overweight, obese group according to body mass index $(22.9kg/m^2\;and\;below\;/\;23{\sim}24.9kg/m^2\;/\;25kg/m^2\;and\;above)$and investigated the relationship between obesity based on body mass index(BMI) and cardiovascular risk factors. And investigated the relationship between each cardiovascular risk factor and body mass index, waist-hip ratio, body fat percent. Results: With the exception of blood pressure, other lab data such as total cholesterol, triglycerid, glucose were significantly different between the three groups divided by body mass index$(22.9kg/m^2\;and\;below\;/\;23{\sim}24.9kg/m^2\;/\;25kg/m^2\;and\;above)$. And Correlation coefficient of cardiovascular risk factors with body mass index, waist-hip ratio, body fat precent were acquired. Conclusion: We have concluded that the body mass index and waist-hip ratio body fat precent were predictive factors cardiovascular disease.

• Journal of The Korean Society of Integrative Medicine
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• v.4 no.2
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• pp.97-107
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• 2016

Purpose : Cardiovascular disease is major factor of mortality in worldwide. Previous studies shown that the socioeconomic factors, nutrition factors, health behavior factors, biological factors and co-morbidity are increasing a prevalence of cardiovascular disease. Method : This study examined the risk factors for cardiovascular disease among adults aged 30 years and older using the data from the 2012 to 2014 Korean National Health and Nutrition Examination Survey (KNHANES). The study participants were 7,555 Cardiovascular disease includes hypertension, stroke, angina pactoris, and myocardial infarction. Descriptive statistic and multivariates logistic regression were calculated. Result : The overall prevalence of cardiovascular disease was 31.16% in the participants. Cardiovascular disease was significantly associated with gender, age, income, education, marital status as socioeconomic factors in unadjusted model. After adjusting socioeconomic status variables, past smoker (OR 1.27, 95% CI 1.05-1.55), obesity (OR 7.14, 95% CI 4.21-12.11), skipping a meal (OR 2.79, 95% CI 2.46-3.16), HDL-C (OR 0.99, 95% CI 0.98-0.99) and WC (OR 1.06, 95% CI 1.05-1.07) were associated with cardiovascular disease. Conclusion : The results marked the importance of finding high risk groups and an early management of cardiovascular disease.

• Journal of Preventive Medicine and Public Health
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• v.40 no.5
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• pp.411-417
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• 2007

Objectives: Although risk factors for coronary artery disease are also associated with increased carotid intima-media thickness (IMT), there is little information available on the asymptomatic, young adult population. We examined the association between multiple cardiovascular risk factors and the common carotid IMT in 280 young Korean adults. Methods: The data used for this study was obtained from 280 subjects (130 men and 150 women) aged 25 years who participated in the Kangwha Study follow-up examination in 2005. We measured cardiovascular risk factors, including anthropometries, blood pressure, blood chemistry, carotid ultrasonography, and reviewed questionnaires on health behaviors. Risk factors were defined as values above the sex-specific 75th percentile of systolic blood pressure, body mass index, total cholesterol/ high-density lipoprotein cholesterol ratio, fasting blood glucose and smoking status. Results: The mean carotid IMT${\pm}$standard deviation observed was $0.683{\pm}0.079mm$ in men and $0.678{\pm}0.067mm$ in women (p=0.567) and the evidence of plaque was not observed in any individuals. Mean carotid IMT increased with an increasing number of risk factors(p for trend <0.001) and carotid IMT values were 0.665 mm, 0.674 mm, 0.686 mm, 0.702 mm, and 0.748 mm for 0, 1, 2, 3, and 4 to 5 risk factors, respectively. The odds ratio for having the top quartile carotid IMT in men with 3 or more risk factors versus 0-2 risk factors was 5.09 (95% CI, 2.05-12.64). Conclusions: Current findings indicate the need for prevention and control of cardiovascular risk factors in young adults and more focus on those with multiple cardiovascular risk factors.

• Journal of Chest Surgery
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• v.46 no.5
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• pp.346-352
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• 2013

Background: Transcatheter aortic valve implantation (TAVI) has been an alternative to conventional aortic valve replacement (AVR) in old and high risk patients. The goal of this study is to compare the early outcomes of conventional AVR vs. TAVI in high risk severe AS patients. Methods: From January 2008 to July 2012, 44 high risk severe aortic stenosis patients underwent conventional AVR, and 15 patients underwent TAVI. We compared echocardiographic data, periprocedural complication, and survival. The mean follow-up duration was $14.5{\pm}10$ months (AVR), and $6.8{\pm}3.5$ months (TAVI), respectively. Results: AVR group was younger ($78.2{\pm}2.4$ years vs. $82.2{\pm}3.0$ years, p<0.001) and had lower operative risk (Euroscore: $9.4{\pm}2.7$ vs. $11.0{\pm}2.0$, p=0.044) than TAVI group. There was no significant difference in early mortality (11.4% vs. 13.3%, p=0.839), and 1 year survival ($87.4%{\pm}5.3%$ vs. $83.1%{\pm}1.1%$, p=0.805). There was no significant difference in postoperative functional class. There was no significant difference in periprocedural complication except vascular complication (0% [AVR] vs. 13.3% [TAVI], p=0.014). TAVI group had more moderate and severe paravalvular leakage. Conclusion: In this study, both groups had similar periprocedural morbidity, and mortality. However, TAVI group had more greater than moderate paravalvular leakage, which can influence long-term outcome. Since more patients are treated with TAVI even in moderate risk, careful selection of the patients and appropriate guideline need to be established.

• Korean Journal of Adult Nursing
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• v.18 no.3
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• pp.426-435
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• 2006

Purpose: The purpose of this study was to explore the predictors of cardiovascular risk factors among type 2 diabetic patients. Method: Data were collected from November, 2003 to June, 2004 using a physiological index and questionnaires. Patients(N=159) aged 40 and above were conveniently recruited from health care centers in B city. Data were analyzed with descriptive statistics, Pearson correlation and stepwise multiple regression using SPSS WIN 10.0 program. Results: The cardiovascular risk factors were negatively related with female gender, household monthly income, educational experience about diabetes, physical activity, self-care, self-efficacy and problem oriented coping, while positively related with the duration of diabetes, diabetic family history and depression. Self-care, diabetic family history, female gender, monthly household income, self-efficacy, affective-oriented coping and physical activity predicted 41.5% of the variance in cardiovascular risk factors of diabetic patients. Conclusion: According to the findings of this study, we concluded that cardiovascular risk factors of type 2 diabetic patients are related to the modifiable and non-modifiable variables. Self-care, self-efficacy, affective oriented coping, and physical activity were identified as modifiable variables. Intervention programs to increase those variables are warranted to reduce cardiovascular risk factors among type 2 diabetic patients.

• Korean Journal of Adult Nursing
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• v.14 no.2
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• pp.233-243
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• 2002

Purpose: This study is aimed at testing the effect of health promotion program on health promoting behavior and cardiovascular risk factors of middle-aged women. Method: The research design was the nonequivalent control group pre-post test. Twelve middle-aged women were the experimental group and ten were the control group. The 8-week health promotion program was given to the experimental group. There were health promotion theories, flexibility and muscle strength exercise, cardiopulmonary endurance exercise, nutrition, stress management, cancer prevention and early detection, management of menopause and wrap-up in health promotion program for middle-aged women. The measurement tool was Health Promoting Behavior developed by researcher using serum cholesterol, obesity rate, systolic blood pressure, and diastolic blood pressure as cardiovascular risk factors. Result: The experimental group showed a higher score of health promoting behavior than the control group. There were no differences on cardiovascular risk factors(cholesterol, obesity rate, diastolic blood pressure) between the experimental and control groups except systolic blood pressure. Conclusion: Conclusively, this health promotion program for middle-aged women was effective in increasing health promotion behaviors, but wasn't effective in decreasing cardiovascular risk factors except the systolic blood pressure. It seems it's necessary to re-study this using more samples and a longer duration of the program, and smaller mortality rate.