• Archives of Pharmacal Research
• /
• 제25권6호
• /
• pp.747-758
• /
• 2002

The skin displays a highly active metabolism of polyunsaturated fatty acids (PUFA). Dietary deficiency of linoleic acid (LA), an 18-carbon (n-6) PUFA, results in characteristic scaly skin disorder and excessive epidermal water loss. Although arachidonic acid (AA), a 20-carbon (n6) PUFA, is metabolized via cyclooxygenase pathway into predominantly prostaglandin $E_2(PGE_2)$ and $PGF_{2{\alpha}}$, the metabolism of AA via the 15-lipoxygenase (15-LOX) pathway, which is very active in skin epidermis and catalyzes the transformation of M into predominantly 15S-hydroxyeicosatetraenoic acid (15S-HETE). Additionally, the 15-LOX also metabolizes the 18-carbon LA into 13S-hydroxyoctadecadienoic acid (13S-HODE), respectively. Interestingly, 15-LOX catalyzes the transformation of $dihomo-{\gamma}-linolenic$ acid (DGLA), derived from dietary gamma-linolenic acid, to 15S-hydroxyeicosatrienoic acid (15S-HETrE). These monohydroxy fatty acids are incorporated into the membrane inositol phospholipids which undergo hydrolytic cleavage to yield substituted-diacylglycerols such as 13S-HODE-DAG from 13S-HODE and 15S-HETrE-DAG from 15S-HETrE. These substituted-monohydroxy fatty acids seemingly exert anti-inflammatory/antiproliferative effects via the modulation of selective protein kinase C as well as on the upstream/down-stream nuclear MAP-kinase/AP-1/apoptotic signaling events.

• 한국분말재료학회지
• /
• 제22권4호
• /
• pp.289-297
• /
• 2015

As recognized by all scientific and industrial groups, carbon dioxide($CO_2$) capture and storage(CCS) could play an important role in reducing greenhouse gas emissions. Especially carbon capture technology by dry sorbent is considered as a most energy-efficient method among the existing CCS technologies. Patent analysis has been considered to be a necessary step for identifying technological trend and planning technology strategies. This paper is aimed at identifying evolving technology trend and key indicators of dry sorbent from the objective information of patents. And technology map of key patents is also presented. In this study the patents applied in korea, japan, china, canada, US, EU from 1993 to 2013 are analyzed. The result of patent analysis could be used for R&D and policy making of domestic CCS industry.

• 한국지형학회지
• /
• 제23권3호
• /
• pp.67-78
• /
• 2016

Soil carbon(C) is an essential property for characterizing soil quality. Understanding spatial patterns of soil C is particularly limited for mountain areas. This study aims to predict the spatial pattern of soil C using terrain analysis in a steep mountainous area. Specifically, model performances and prediction uncertainties were investigated based on the number of resampling repetitions. Further, important predictors for soil C were also identified. Finally, the spatial distribution of uncertainty was analyzed. A total of 91 soil samples were collected via conditioned latin hypercube sampling and a digital soil C map was developed using support vector regression which is one of the powerful machine learning methods. Results showed that there were no distinct differences of model performances depending on the number of repetitions except for 10-fold cross validation. For soil C, elevation and surface curvature were selected as important predictors by recursive feature elimination. Soil C showed higher values in higher elevation and concave slopes. The spatial pattern of soil C might possibly reflect lateral movement of water and materials along the surface configuration of the study area. The higher values of uncertainty in higher elevation and concave slopes might be related to geomorphological characteristics of the research area and the sampling design. This study is believed to provide a better understanding of the relationship between geomorphology and soil C in the mountainous ecosystem.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• 제18권4호
• /
• pp.903-921
• /
• 2024

Industry 5.0 puts forward higher requirements for smart cities, including low-carbon, sustainable, and people-oriented, which pose challenges to the design of smart cities. In response to the above challenges, this study introduces the cyber-physical-social system (CPSS) and parallel system theory into the design of smart cities, and constructs a smart city framework based on parallel system theory. On this basis, in order to enhance the security of smart cities, a sustainable patrol subsystem for smart cities has been established. The intelligent patrol system uses a drone platform, and the trajectory planning of the drone is a key problem that needs to be solved. Therefore, a mathematical model was established that considers various objectives, including minimizing carbon emissions, minimizing noise impact, and maximizing coverage area, while also taking into account the flight performance constraints of drones. In addition, an improved metaheuristic algorithm based on ant colony optimization (ACO) algorithm was designed for trajectory planning of patrol drones. Finally, a digital environmental map was established based on real urban scenes and simulation experiments were conducted. The results show that compared with the other three metaheuristic algorithms, the algorithm designed in this study has the best performance.

• 생물환경조절학회지
• /
• 제32권4호
• /
• pp.267-277
• /
• 2023

본 연구는 '대홍' 복숭아를 대상으로 수확 후 1-MCP 처리와 MAP가 저온 저장 중 복숭아 '대홍'의 품질 변화에 미치는 영향을 알아보고자 수행하였다. 1-MCP는 1µL·L^-1과 2µL·L^-1 농도로 처리하여, MAP 포장 후 온도 5±1℃, 습도 85±5%의 저온 저장고에서 28일 저장하였고, 포장 대조구로 골판지 상자를 설정하여 품질변화를 비교하였으며, 각각의 포장 처리구에는 1-MCP를 처리하지 않은 대조구로 두었다. 저장 중 생체중 감소율은 MAP 포장구에서 1-MCP 처리구와 무처리구 과실 간에 유의한 차이가 없었으며 MAP보다 골판지 상자 포장구의 과실에서 감소율이 높았다. 호흡률과 에틸렌 발생률은 1µL·L^-1 처리구와 2µL·L^-1 처리구에서 유사한 경향을 나타내었고, 대조구는 1-MCP 처리구와 통계적 유의성을 보이며 높게 발생하였다. 포장 내 이산화탄소는 1-MCP 처리구에서 12% 내외로 무처리구에 비해 낮았고, 에틸렌은 1µL·L^-1 처리구의 과실에서 다른 처리구와 유의성을 보이며 가장 낮게 유지되었다. 저장 기간이 경과할수록 경도는 대조구보다 1-MCP와 MAP를 처리한 과실에서는 9%(1µL·L^-1 MAP)와 5%(2µL·L^-1 MAP)로 유의하게 연화가 억제되었다. 과피와 과육의 Hunter a^* 값은 1µL·L^-1 처리구에서 대조구보다 유의하게 높았고, 안토시아닌도 1µL·L^-1 처리구에서 다른 처리구에 비해 저장 중 높은 값을 나타내었으며, 특히MAP 포장한 과실에서 높았다. 위의 결과를 종합해 보면, 1µL·L^-1를 처리한 MAP 포장구에서 '대홍' 복숭아의 저장 중 호흡률 및 에틸렌 발생량이 낮았고 경도, 과피와 과육의 Hunter a^* 및 안토시아닌 함량 변화가 적은 것으로 조사되어 '대홍' 복숭아의 저장 중 품질 유지에 가장 적합하다고 판단된다.

• Corrosion Science and Technology
• /
• 제10권2호
• /
• pp.52-59
• /
• 2011

Corrosion of metallic materials occurs by the reaction with corrosive environment such as atmosphere, marine, soil, urban, high temperature etc. In general, reduction of thickness and cracking and degradation are resulted from corrosion. Corrosion in all industrial facilities and infrastructure causes large economic losses as well as a large number of accidents. Economic loss by corrosion has been reported to be nearly 1-6% of GNP or GDP. In order to reduce corrosion damage of industrial facilities, corrosion map as well as a systematic investigation of the loss of corrosion in each industrial sector is needed. The Corrosion Science Society of Korea in collaboration with 15 universities and institutes has started to survey on the cost of corrosion and corrosion map of Korea since 2005. This work presents the results of the survey on cost of corrosion by Uhlig, Hoar, and input-output methods, and the evaluation of atmospheric corrosion rate of carbon steel, weathering steel, galvanized steel, copper, and aluminum in Korea. The total corrosion cost was estimated in terms of the percentage of the GDP of industry sectors and the total GDP of Korea. According to the result of Input/output method, corrosion cost of Korea was calculated as 2.9% to GDP (2005). Time of wetness was shown to be categories 3 to 4 in all exposure areas. A definite seasonal difference was observed in Korea. In summer and fall, time of wetness was higher than in other seasons. Because of short exposure period (12 months), significant corrosion trends depending upon materials and exposure corrosion environments were not revealed even though increased mass loss and decreased corrosion rate by exposure time.

• 한국잠사학회:학술대회논문집
• /
• 한국잠사학회 1997년도 Progress and Future Development of Sericultural Science and Technology 40th Anniversary Commemoration Symposium
• /
• pp.23-49
• /
• 1997

This is a progress report of rice biotechnology including development of gene transformation system, gene cloning and molecular mapping in rice. The scope of the research was focused on the connection between conventional breeding and biotech-researches. Plant transformation via Agrobacterium or particle bombardment was developed to introduce one or several genes to recommended rice cultivars. Two chimeric genes containing a maize ribosome inactivating protein gene (RIP) and a gerbicide resistant gene (bar) were introduced to Nipponbare, a Japonica cultivar, and transmitted to Korean cultivars. The homozygous progenies of herbicide resistant transgenic plant showed good fertility and agronomic characters. To explore the genetic resourses in rice, over 8,000 cDNA clones from immature rice seed have been isolated and sequenced. About 13% of clones were identified as enzymes related to metabolic pathway. Among them, twenty clones have high homology with genes encoding enzymes in the photorespiratory carbon cycle reaction. Up to now about 100 clones were fully sequenced and registered at EMBL and GenBank. For the mapping of quantitative tarits loci (QTL) and eternal recombinant inbred population with 164 F13 lines (MGRI) was developed from a cross between Milyang 23 and Gihobyeo, Korean rice cultivars. After construction of fully saturated RFLP and AFLP map, quantitative traits using MGRI population were analyzed and integrated into the molecular map. Eighty seven loci were determined with 27 QTL characters including yield and yield components on rice chromosomes. Map based cloning was also tried to isolate semi-dwarf (sd-1) gene in rice. A DNA probe, RG 109, the most tightly linked to sd-1 gene was used to screen from bacterial artifical chromosome (BAC) libraries and five over lapping clones presumably containing sd-1 gene were isolated. Rice genetic database including results of biotech reasearch and classical genetics is provided at Korea Rice Genome Server which is accessible with world wide web (www) browser. The server provides rice cDNA sequences and map informations linked with phenotypic images.

• BMB Reports
• /
• 제45권2호
• /
• pp.59-70
• /
• 2012

Carbon catabolite repression (CCR) is a key regulatory system found in most microorganisms that ensures preferential utilization of energy-efficient carbon sources. CCR helps microorganisms obtain a proper balance between their metabolic capacity and the maximum sugar uptake capability. It also constrains the deregulated utilization of a preferred cognate substrate, enabling microorganisms to survive and dominate in natural environments. On the other side of the same coin lies the tenacious bottleneck in microbial production of bioproducts that employs a combination of carbon sources in varied proportion, such as lignocellulose-derived sugar mixtures. Preferential sugar uptake combined with the transcriptional and/or enzymatic exclusion of less preferred sugars turns out one of the major barriers in increasing the yield and productivity of fermentation process. Accumulation of the unused substrate also complicates the downstream processes used to extract the desired product. To overcome this difficulty and to develop tailor-made strains for specific metabolic engineering goals, quantitative and systemic understanding of the molecular interaction map behind CCR is a prerequisite. Here we comparatively review the universal and strain-specific features of CCR circuitry and discuss the recent efforts in developing synthetic cell factories devoid of CCR particularly for lignocellulose-based biorefinery.

• 한국포장학회지
• /
• 제28권3호
• /
• pp.223-229
• /
• 2022

파프리카 저장 및 유통 전 처리와 포장방법이 저장성 및 미생물 제어에 미치는 영향에 대해 알아보고자 수행되었다. 이산화염소 가스 3, 6, 12시간과 저온 플라즈마 가스 1, 3, 6시간 처리 후 골판지 박스로 포장하여 8±1℃ 챔버에서 7일간 저장 하였을 때, 이산화염소 12시간 처리와 플라즈마 6시간 처리가 대장균과 곰팡이 발현을 낮추는 것으로 나타났다. 이에 무처리 대조구와 이산화염소 12시간, 플라즈마 6시간 처리한 후 골판지 박스 포장과 MAP 처리를 하여 8±1℃ 챔버에서 20일간 저장하였다. 저장 중 생체중 감소는 MAP 처리구가 1% 미만의 수치를 보였고, 외관상 품질은 MAP 처리구가 저장 종료일까지 상품성 한계점 이상이었다. 필름 내 산소, 이산화탄소, 에틸렌 농도는 처리구간의 차이가 나타나지 않았다. 경도의 경우 이산화염소 처리구가 낮았고, 색도를 나타낸 Hunter a^* 값은 MAP 처리구에서 증가하였다. 이취는 MAP 처리구에서 측정되었지만 매우 낮았다. 파프리카 과경의 곰팡이 발생률은 이산화염소 처리 박스 포장 처리구가 가장 빠르고 높게 발생하였고, 이산화염소 처리 MAP 처리구가 가장 낮았다. 저장 종료일 과육의 총 세균수는 플라즈마 처리 박스 포장 처리구, 대장균수는 이산화염소 처리 MAP 처리구, 곰팡이는 이산화염소 처리 박스 포장 처리구가 가장 낮았다. 이상의 결과를 종합해보면, 파프리카 저장 중 미생물 억제를 위해 포장 방법과 관계없이 저장 전 플라즈마를 6시간 처리하는 것이 적합하다고 판단된다.

• 농업생명과학연구
• /
• 제45권3호
• /
• pp.35-41
• /
• 2011

이 연구에서는 지리적 여건 및 임업경영 여건을 고려하여 우리나라의 목재공급 잠재량을 예측하고자 하였다. 현실적으로 목재생산이 가능한 지역을 추출하기 위하여 목재생산지를 자연적, 이론적, 지리적, 기술적 목재생산지로 구분하여 분석을 수행하였다. 먼저 수치임상도를 이용하여 전체 산림으로부터 입목지를 추출하여 자연적 목재생산지를 구분하였다. 다음으로 법정용도지역, 경사도, 하천 그리고 도로 여건을 고려하여 이론적, 지리적, 기술적 목재생산지를 추출하였다. 입목축적량을 산출하기 위하여 수치임상도의 수종 및 영급에 대한 속성자료를 이용하였으며, 기술적 목재생산지에 대한 임목축적량을 산출함으로써 목재공급 잠재력을 평가하였다. 각 유형별 목재생산지에 대한 자원량을 산출한 결과는 244,150천$m^3$에서부터 596,248천$m^3$에 이르기까지 자원량의 편차가 크게 나타나 지리적 여건 및 임업경영 여건의 고려 수준에 따라 잠재력이 고평가 혹은 저평가 될 수 있는 것으로 나타났다. 지역별 목재공급 잠재량을 분석한 결과에서는 경상북도, 전라남도, 경상남도, 강원도의 순으로 잠재량이 높은 것으로 평가되었다.