• Title/Summary/Keyword: Capsulation

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(An) experimental study on the development of lightweight concrete using the PCM (PCM 혼입 경량기포콘크리트 패널 개발을 위한 기초적 연구)

  • Lim, Myung Kwan;Enkhbold, Odontuya;Kim, Young Ho;Choi, Dong Uk
    • KIEAE Journal
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    • v.14 no.4
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    • pp.133-138
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    • 2014
  • The present study was carried out to assess the basic material properties and thermal behavior of light-weight foamed concrete panel mixed with PCM (Phase Changing Material). To do so, this study fabricated light-weight foamed concrete (1.0kg/m3) in pre-foaming method and mixed it with PCM micro capsule of 1-dodecanol and melamine to examine its physical and thermal properties. The results confirmed strength reinforcement effect by proper replacement ratio of fly-ash, which is an industrial by-product, and PCM. In addition, it found out that PCM-mixed light-weight foamed concrete had time delay and temperature reduction effect within the range of PCM phase transition according to the rise of outdoor temperature. It was also observed that the insulation performance of PCM-mixed light-weight foamed concrete was more dependent upon thickness than PCM replacement ratio.

Status, Antimicrobial Mechanism, and Regulation of Natural Preservatives in Livestock Food Systems

  • Lee, Na-Kyoung;Paik, Hyun-Dong
    • Food Science of Animal Resources
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    • v.36 no.4
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    • pp.547-557
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    • 2016
  • This review discusses the status, antimicrobial mechanisms, application, and regulation of natural preservatives in livestock food systems. Conventional preservatives are synthetic chemical substances including nitrates/nitrites, sulfites, sodium benzoate, propyl gallate, and potassium sorbate. The use of artificial preservatives is being reconsidered because of concerns relating to headache, allergies, and cancer. As the demand for biopreservation in food systems has increased, new natural antimicrobial compounds of various origins are being developed, including plant-derived products (polyphenolics, essential oils, plant antimicrobial peptides (pAMPs)), animal-derived products (lysozymes, lactoperoxidase, lactoferrin, ovotransferrin, antimicrobial peptide (AMP), chitosan and others), and microbial metabolites (nisin, natamycin, pullulan, ε-polylysine, organic acid, and others). These natural preservatives act by inhibiting microbial cell walls/membranes, DNA/RNA replication and transcription, protein synthesis, and metabolism. Natural preservatives have been recognized for their safety; however, these substances can influence color, smell, and toxicity in large amounts while being effective as a food preservative. Therefore, to evaluate the safety and toxicity of natural preservatives, various trials including combinations of other substances or different food preservation systems, and capsulation have been performed. Natamycin and nisin are currently the only natural preservatives being regulated, and other natural preservatives will have to be legally regulated before their widespread use.

Graphene nanosheets encapsulated poorly soluble drugs with an enhanced dissolution rate

  • Shen, Shou-Cang;Ng, Wai Kiong;Letchmanan, Kumaran;Lim, Ron Tau Yee;Tan, Reginald Beng Hee
    • Carbon letters
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    • v.27
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    • pp.18-25
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    • 2018
  • In this study, graphene oxide(GO) was used as drug carriers to amorphize poorly watersoluble drugs via a co-spray drying process. Two poorly water-soluble drugs, fenofibrate and ibuprofen, were investigated. It was found that the drug molecules could be in the graphene nanosheets in amorphous or nano crystalline forms and thus have a significantly enhanced dissolution rate compared with the counterpart crystalline form. In addition, the dissolution of the amorphous drug enwrapped with the graphene oxide was higher than that of the amorphous drug in activated carbon (AC) even though the AC possessed a larger specific surface area than that of the graphene oxide. The amorphous formulations also remained stable under accelerated storage conditions ($40^{\circ}C$ and 75% relative humidity) for a study period of 14 months. Therefore, graphene oxide could be a potential drug carrier and amorphization agent for poorly water-soluble drugs to enhance their bioavailability.

A Study on the Environmental Fraternized Preparation of Inorganic/organic Core-shell Binder (환경친화적인 무기/유기 Core-Shell의 제조에 관한 연구)

  • Seoul, Soo-Duk;Lim, Jae-Keel;Lim, Jong-Min;Kwon, Jae-Beom;Lee, Nae-Woo
    • Journal of the Korean Society of Safety
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    • v.19 no.1
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    • pp.81-87
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    • 2004
  • Composite particles using inorganic and organic chemicals were synthesized and the results of those reaction were compared to variation of temperature and agitation speed in presence of $CaCO_3$ which was adsorbed SDBS. Also the synthesises were optimized according to conversion rate of composite particles. In inorganic/organic core-shell composite particle polymerization, $CaCO_3$ adsorbed by 0.5wt% surfactant SDBS was prepared initially and then core $CaCO_3$ was encapsulated by sequential emulsion polymerization using MMA at the addition of APS 3.16${\times}$$10^{-3}$mol/L to minimize the coagulated PMMA particle itself during MMA shell polymerization. Encapsulated PMMA on $CaCO_3$ as inorganic/organic core-shell particles was verified by FT-IR and DSC analysis. It was found that the $CaCO_3$ was very well encapsulated by PMMA as shell. The surfaces were distinctly found as spindle shape and broad particle distribution after capsulation.

Studies on Inactivated Combined Vaccine of Bovine Anthrax and Blackleg (소의 탄저기종저 불활화 혼합백신에 관한 연구)

  • Jeon, Yun Seong
    • Korean Journal of Veterinary Research
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    • v.10 no.1
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    • pp.5-10
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    • 1970
  • Due to the fact that an inactivated anthrax vaccine may lark its immunogenicity and stability of immunogen a number of spore vaccines were exclusively used worldwide. In these studies a number of important factors were emphasized to achieve the following: selection of non or less allergic strain of anthrax bacillus, capsulation of bacteria. obtaining of non sporulating but vegetative organisms, adequate inactivation of B. anthraccis by means of formalin, adsorption of immunogen to aluminum hydroxide gel. Non or less allergic strains of anthrax bacillus which is inactivated with formalin was selected by a hyperimmunization and shock test in rabbits. Obtaining capsular material and vegetative immunogen, a virulent anthrax organisms were cultivated on sodium bicarbonate medium with of without adding of l-alanine in which B, anthracis grew luxuriantly without forming spores. Inactivation was carried out at $37^{\circ}C$ water bath for 3 days after the bacterial culture was mixed with formalin, in a final concentration of two per cent of formalin. Aluminum hydroxide gel was added to the mixture of anthrax and blackleg bacterin. Vaccines were injected guinea pig via subcutaneous or intramusoular route and challenged after three weeks and the possibilities of protection was tested. Throughout the studies. the above mentioned vaccines possibly protected the vaccinated guinea pigs more than 80 per cent compared to that of the controls. This experimental results strongly suggest that the vaccine may possibly applicable to bovine.

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Lipoma on superficial lobe of the parotid gland: case report (이하선 천엽에 발생한 지방종의 치험례)

  • Kim, Jung-Han;Kim, Chul-Hoon;Kim, Min-Gu;Song, Jin-Woo;Jung, Eu-Gene;Kim, Bok-Joo
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.36 no.5
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    • pp.438-440
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    • 2010
  • A lipoma is a benign tumor of matured adipose tissue that usually occurs at the shoulder, back, and abdomen. 13% of lipomas occur in the head and neck area. However, the incidence of lipoma in the parotid gland is very low, approximately 2.5%. A conservational surgical excision is recommended in cases of lipoma of the parotid gland, with only 1-2% of lipomas recurring. We report a case of a lipoma in the parotid gland that was removed by conservational surgical excision. The lesion was exposed by the pre-auricular approach and the tissue was detached. After the parotid gland envelop was exposed, a yellowish mass is observed that was easy to remove due to capsulation. Most authors recommend a surgical excision of the superficial lobe of the parotid gland as the treatment for a lipoma in the parotid gland. However, enucleation only may be a sufficient treatment when a lipoma occurs in the superficial lobe or around the parotid gland. A patidectomy is not needed when a lipoma is located at the superficial lobe of the parotid gland, and a conservational surgical excision is suitable. Therefore, a clinical diagnosis is important for reducing the damage to the facial nerve.

Study on Eveluation of Performancen on Internet Phone(VoIP) using the VPN (VPN을 적용한 인터넷 전화 단말기의 성능평가에 관한 연구)

  • Lee Seong gi;Yoo Seung Sun;Lee Myeong jea;Kwak Hoon-Sung
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.30 no.6A
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    • pp.445-454
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    • 2005
  • To measure the performance of call quality, we have built the experiment environment and observed that the delay caused by encapsulation between internet and VoIP telephones is under 5ms at most. The major delay is assumed to be the time required to capsulate the packet for tunnelling of VPN. Because the difference of average delay time is under $4ms{\sim}5ms$, the difference of call quality between VoIP and VoIP telephone adopting VPN is negligible. We have concluded that the capsulation process between PAC and PNS is the major factor influencing the network load by changing the number of fames in a packet during communication Also, we have concluded that the most suitable frame numbers is tow or three by adding the frame numbers in a packet to obtain the suitable frames in a packet and setting up end-to-end delay under 150ms.

Epithelial-myoepithelial carcinoma on the superficial lobe of the parotid gland: a case report (이하선 천엽에 발생한 상피-근상피암종의 치험례)

  • Jin, Sun-Mi;Ryu, Hyun-Ho;Ryu, Seok-Hwan;Shin, Dong-Yoon;Hwang, Hie-Sung;Kim, Chul-Hoon;Kim, Bok-Joo
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.37 no.6
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    • pp.505-509
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    • 2011
  • Epithelial-myoepithelial carcinoma (EMC) is a low-grade malignant salivary gland neoplasm that was first described in 1972. EMC occurs in the older age group, there is a female predilection and mainly involves the parotid gland. Most authors recommend superficial parotidectomy as a treatment for low-grade malignant tumor in the superficial lobe of parotid gland. The treatment of epithelial-myoepithelial tumors typically includes surgical excision aimed at achieving a R0 resection. This paper reports a case of EMC of the parotid gland treated only by a conservational surgical excision. The lesion was exposed by the retromandibular approach and detached. After the parotid gland envelop was exposed, the mass was observed and was easy to remove due to capsulation. The preoperative diagnosis was a pleomorphic adenoma on the left parotid gland. The tumor was removed surgically with a conservative extracapsular dissection. The postoperative diagnosis was EMC, so superficial parotidectomy or radiation therapy was considered. Nevertheless, the patient was observed and no additional treatment was attempted because the patient was old and a successfully excision of the tumor had been achieved.

The Manufacturing Mechanism of Nano-some and Method of Capsulation of Kojic Acid and Kojic Dipalmitate with Hydrogenated Lecithin and Co-emulsifiers (Hydrogenated Lecithin 과 Co-emulsifier를 사용한 Nano-some의 제조 메커니즘과 Kojic Acid 및 Kojic Dipalmitate의 캡슐화 방법)

  • Kim, In-Young;Jae, Koo-Hwan;Lee, Joo-Dong
    • Journal of the Korean Applied Science and Technology
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    • v.17 no.4
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    • pp.248-256
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    • 2000
  • We investigated the property of formation of mono-vesicle(designated nano-some) with using of the combined co-emulsifiers and phospholipid. Nano-some was prepared with hydrogenated lecithin(HL) and diethanolamine cetyl phosphate(DEA-CP) by swelling reaction. Kojic acid and kojic dipalmitate could be made stabilization by nano-some system using microfluidizer(MF). Nano-some has a good affinity to skin by means of this system. The composition was compounded by 2% of hydrogenated lecithin (phosphatidyl choline contained with 75%, 0.5% of DEA-CP and 0.5% of diglyceryl dioleate (DGDO). To make nano-some, several conditions of MF have to be considered as follows. The optimum pH was 6.0. The pressure was 10,000psi and passage temperature was at $306^{\circ}C$. The nano-some base was passed to homogenize continually 3 times through MF. The Particle size distributions of the vesicles were with in $57{\sim}75.7nm$(mean 66nm) by measuring the Zetasizer-3000. Zeta potential of vesicles with 3 times passage through MF was -24.8mV. Formations for nano-some vesicle certificated photograph by scanning electric magnification (SEM). Stability of nano-some was very good for 6months. The turbidity was very good transparency compared nano-some with liposome. It was formed the mono vesicle in the opposite direction to be formed the multi-lamellar vesicle of liposome.

Effects of the Proportions of Wall Materials on the Characteristics of Spray Dried Vinegar (부형제의 혼합비에 따른 분말식초의 품질 특성)

  • 황성희;홍주헌;정용진;윤광섭
    • Food Science and Preservation
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    • v.9 no.2
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    • pp.189-193
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    • 2002
  • This study was conducted to evaluate the quality and the quantity for manufacturing vinegar powder using spray drying. The $\beta$-cyclodextrin(CD) and gum arabic(GA) were used as well materials and the mixing ratio of CD and GA was ranged from 10:0 to 0:10. The moisture content of the vinegar powder of 2.5 of CD and 7.5 of GA was lowest among the other mixing ratios. At this proportion, the titratable acidity was highest as it had much included vinegar. The heat stability was not varied much with mixing ratio. However the stability of heat was maintained. Further the water absorption of powder was comparatively low. The manufactured powder vinegar shape was smooth round particles and stable structure by SEM and the particle size was small enough to form capsulation. In sensory evaluation, under these conditions the sourness was highest at 3.5. Therefore, the optimal mixing ratio at 2.5 of CD and 7.5 of GA in wall material was selected.