• Title/Summary/Keyword: Capillary Tension

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A Study on the Pulmonary Hemodynamic Changes before and after PEEP in ARDS (호흡부전증에세 호기말 양압호흡법 치료 전후의 폐혈류역학적 변화에 관한 연구)

  • Chung, June-Key;Shin, Seong-Hae;Khang, Shin-Kwang;Park, Sung-Ki;Lee, Myung-Chul;Cho, Bo-Youn;Koh, Chang-Soon;Kim, Yong-Lack;Kim, Kwang-Woo
    • The Korean Journal of Nuclear Medicine
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    • v.18 no.1
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    • pp.45-53
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    • 1984
  • The purpose of this study is to observe the changes of pulmonary capillary permeability and various hemodynamic parameters before and after Positive End-Expiratory Pressure(PEEP) in Adult Respiratory Distress Syndrome (ARDS). Using a canine oleic acid induced ARDS model, we measured the pulmonary capillary permeability with a slope of lung: heart radioactivity ratio, hemodynamic parameters with Swan-Ganz catheter and blood gas tensions. 1) In normal and ARDS dogs, the PEEP didn't significantly influence the slope of lung: heart radioactivity ratio. But in ARDS group the slope index was increased compaired with that of control group (p<0.05). 2) Also in ARDS group, $PaO_2$ was significantly decreased, and $PaCO_2,\;PvCO_2$, MPAP, $AaDO_2$, Qs/Qt were significantly increased compared with those of control group (p<0.05). 3) In normal dogs, the PEEP didn't influence blood pH or gas tension, $AaDO_2$, Qs/Qt, or hemodynamics. 4) In ARDS dogs, however, the PEEP significantly increased $PaO_2$ and decreased $AaDO_2$, Qs/Qt (p<0.05).

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Numerical Investigation on Two-Dimensional Inviscid Edge Receeding of a Stationary Fluid Sheet (정지된 2차원 액체 필름 끝단의 비점성 수축특성에 관한 수치연구)

  • Ahn, Ja-Il;Song, Mu-Seok
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.10 no.2
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    • pp.107-111
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    • 2007
  • A two-dimensional numerical method for inviscid two-fluid flows with evolution of density interface is developed, and an initially stationary two-dimensional fluid sheet surrounded by another fluid is studied. The interface between two fluids is modeled as a vortex sheet, and the flow field with the evolution of interface is solved by using vortex-in-cell/front-tracking method. The edge of the sheet is pulled back into the sheet due to surface tension and a blob is formed at the edge. This blob and fluid sheet are connected by a thin neck. In the inviscid limit, such process of the blob and neck formation is examined in detail and their kinematic characteristics are summarized with dimensionless parameters. The edge recedes at and the capillary wave propagating into the fluid sheet must be considered for better understanding of the edge receding.

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Coherent x-ray scattering to study dynamics in thin films (결맞는 X-선 산란을 이용한 박막의 표면 거동 연구)

  • Kim, Hyun-Jung
    • Journal of the Korean Vacuum Society
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    • v.14 no.3
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    • pp.143-146
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    • 2005
  • A new method of x-ray photon correlation spectroscopy (XPCS) using coherent x-rays is developed recently for probing the dynamics of surface height fluctuations as a function of lateral length scale. This emerging technique applies the principles of dynamic light scattering in the x-ray regime. The short wavelength and slow time scales characteristic of XPCS extend the phase space accessible to scattering studies beyond some restrictions by light and neutron. In this paper, we demonstrate XPCS to study the dynamics of surface fluctuations in thin supported polymer films. We present experimental verification of the theoretical predictions for the wave vector and temperature dependence of the capillary wave relaxation times for the supported polymer films at melt for the film thicknesses thicker than 4 times of the radius of gyration of polymer. We observed a deviation from the conventional capillary wave predictions in thinner films. The analysis will be discussed in terms of surface tension, viscosity and effective interactions with the substrate.

Effects of Sagungsan on the Hemostasis, Intracranial Pressure, Blood Pressure and Cardiovascular System in Expreimental Animals (사궁산(莎芎散)이 실험동물(實驗動物)의 지혈(止血), 뇌압(腦壓), 혈압(血壓) 및 심혈관계(心血管系)에 미치는 영향(影響))

  • An, Il-Hoe;Park, Young-Soon;Kim, Seh-Gil
    • The Journal of Internal Korean Medicine
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    • v.15 no.1
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    • pp.80-98
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    • 1994
  • According to the original documents, Sagungsan is considered as an effective drug for controlling the hypertensive epistaxis induced by tension of autonomic nerve and it's hyperfunction. The present experiment was designed to understand the effect of Sagungsan extract on the hemostatic action, intracranial pressure, blood pressure and cardiovascular system in experimental animals. And thus the bleeding time, prothrombin time, capillary dilation, blood pressure, Intracranial pressure, and enzymatic analysis of the ATPase activities were studied. The result obtained here were as followings: 1. Sagungsan water extract reduced the bleeding time in mouse, and prolonged the prothrombin time in rabbits. 2. The drug extract increased the tail volume by capillary dilation in rats. 3. The drug extract inhibited the increase of intracranial pressure and arterial blood pressure in rabbits. 4. At the early time, the increase of arterial blood pressure by the drug extract significantly inhibited by pretreated atropin and regitine in rabbits. 5. The drug extract relaxed the smooth muscle by stimulating the Mg2+-Ca2+-ATPase activities of gastric sarcoplasmic reticulum isolated from rabbit stomach. 6. The drug extract stimulated the heart contraction by inhibiting the $Mg^{2+}-Ca^{2+}-ATPase$ activities of cardiac sarcoplasmic reticulum isolated from rabbit heart. The inhibitory mechanism was reversible and noncompatitive. 7. The drug extract increased the hepatic blood volume by stimulating the hepatic total ATPase activities and hepatic metabolism. 8. The drug extract acted as a tranquilizer by inhibiting the neural Na+-K+-ATPase activity. According to the results, Sagungsan water extract dilated the capillaries, stimulated the heart beat, and thus increased the blood flow with decreasing the intracranial pressure and blood pressure. These effects stanches the epistaxis collectively.

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Optimization of Ascorbic Acid Encapsulation in PLA Microcapsules Using Double Emulsion Process (이중유화법을 이용한 PLA 마이크로캡슐 내부로의 아스코르브산 캡슐화 공정 최적화)

  • Ji Won Yun;Young Mi Chung
    • Applied Chemistry for Engineering
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    • v.35 no.2
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    • pp.115-121
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    • 2024
  • This study analyzed the influence of process variables affecting the thermodynamic equilibrium and fluid dynamics of interfaces such as reverse micelle, salt concentration, interfacial tension, and viscosity of fluids to optimize the microencapsulation process using the W1/O/W2 double emulsion method. The process variable with the greatest impact on encapsulation efficiency was found to be the difference in osmotic pressure between the W1 and W2 phases. It was observed that increasing the salt concentration in the W2 phase or decreasing the ascorbic acid concentration in the W1 phase resulted in higher encapsulation efficiency. Additionally, a larger difference in osmotic pressure led to increased damage to the surface of the microparticles, as confirmed by SEM images. The introduction of reverse micelles, which was anticipated to increase encapsulation efficiency, either had a low contribution or even decreased encapsulation efficiency. The yield of microcapsules was expressed as a universal function, applicable to all process conditions or solution compositions. According to this universal function, no further increase in yield was observed beyond the Ca (capillary number) of approximately 20.

AN EXPERIMENTAL STUDY ON THE VASCULAR CHANGES OF RAT MOLAR PERIODONTAL LIGAMENT FOLLOWING ORTHODONTIC TOOTH MOVEMENT USING VASCULAR CORROSION CASTING METHOD (백서구치의 실험적 치아이동시 치근막 혈관변화에 관한 혈관주형법을 이용한 연구)

  • Lim, Yong-Kyu;Yang, Won-Sik
    • The korean journal of orthodontics
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    • v.24 no.1 s.44
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    • pp.37-62
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    • 1994
  • This study was undertaken to investigate the three dimensional vascular changes of periodontal ligament following orthodontic tooth movement. Experimental tooth movement was carried out in 96 Sprague-Dawley rats with the weight of 250g. They were divided into four experimental groups (each 24 rats). The left maxillary first molar was moved mesially with 25g force in group I, and with 75g force in group II. Each three animals were sacrificed after 1, 6, 12, 24 hours, and 3, 7, 14, 21 days. In group III, 25g mesial force was applied for 3 days, and in group IV, 75g mesial force was applied for 3 days. Then the appliances were removed, and each three animals were sacrificed after 1, 6, 12, 24 hours, and 3, 7, 14, 21 days from removal of appliance. The contralateral molars were used for control group. Casting media was injected via left ventricle and polymerized in warm water. After corrosion of surrounding soft tissue, three dimensional vascular changes were examined using scanning electron microscopy. The findings of this study were as follows: 1. Pressure side of group I and II showed degenerative vascular changes such as vascular compression, reduction of vasculature, leakage of casting media. But, regenerative changes were dominant after 7 days of tooth movement. Although the degenerative vascular changes were more severe in group II, which was exposed to heavy force, the timing of these changes was not different between two groups. 2. Periodontal vasculature was reestablished by the growth of new capillaries and their differentiation and union from the remaining periodontal vessels and vessels of alveolar bone marrow. Although vascular regeneration was more rapid in group I, which was exposed to light force, the vasculature was not fully normalized in both groups even after 21 days. 3. There was no remarkable changes in tension side of group I and II, but looping of capillary, new capillary growth, dilation of vessels, redirection of vessels in the direction of tensile force were occurred. 4. In pressure side of group III and IV, in which appliance was removed after 3 days of orthodontic force, bone resorption was continued even after removal of appliance. Regeneration of vasculature was initiated after 1-6 hours, and it was more rapid in group III than group IV. In both groups, the vasculature was not fully normalized even after 21 days. 5. After removal of appliance, tension side of group III and IV showed vascular compression and loss of vasculature.

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A HISTOLOGIC AND AUTORADIOGRAPHIC STUDY ON THE EARLY CHANGES IN THE MOVEMENTS OF RAT INCISORS (백서의 전치 이동시 초기 변화에 관한 조직학적 및 자기방사법적 연구)

  • Yoo, Ki-Whan;Kim, Sang-cheol;Kook, Yoon-A
    • The korean journal of orthodontics
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    • v.23 no.2 s.41
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    • pp.199-216
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    • 1993
  • The purpose of this study was to quantify the biologic effects of the tensile forces from helical springs across the maxillary incisors on the periodontal tissues of rats. 39 Sprague-Dawlely rats were divided into a control group(3 rats) and three experimental groups(36 rats)-group 1, pressured with a light force(50-75g), group 2, with a heavy force(250-300g) and group 3, with a hen force(250-300g) plus laser irradiation. Autoradiographic and histopathologic observations were performed in 12, 24, 48 and 96 hours after force application. The result were as follow : 1. Hyalinized zone of periodontal ligament began to appear at pressure side in 12 hours in group 2 and group 3 ; all decreased in 96 hours except in group 2. 2. Alveolar bone resorption began to appear in 12 hours in group 2 and group 3 ; Group 2 showed more resorption than group 1 and no difference to group 3. 3. Tearing of periodontal ligament and vascular dilatation began to appear at tension side in 12 hours in all groups ; Group 2 showed more changes than group 1 and no difference to group 3 ; Decrease began to appear in 96 hours. 4. New bone formation began to appear at tension side in 12 hours and increased more and more ; No differences were shown of groups 5. New capillary proliferation began to appear at pressure side in 12 hours ; The changes were the greatest in group 3, group 2, group 1, in that order. 6. Positive reaction of cells to $[^3H]-thymidine$ was the greatest in 24 hours of all groups and decreased with times i Group 2 showed more reaction than group 1 and no difference to group 3.

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Model on the Capillary Action-Induced Dynamics of Contact Lens (모세관 작용에 의한 콘택트 렌즈의 운동 모델)

  • Kim, Dae-Soo
    • Journal of Korean Ophthalmic Optics Society
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    • v.6 no.2
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    • pp.85-97
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    • 2001
  • A mathematical model was proposed to analyze the damped motion of contact lens which is initially displaced from the equilibrium position. The model incorporates the differential equations and their numerical solution program, based on the formulations of restoring force arising from the capillary action in the tear-film layer between the lens and cornea. The model predicts the capillary action induced surface tension, time dependence of displacement of lens when it is released from the equilibrium position. It seems that the motion of lens is similar to the typical over-damped oscillation caused by the large viscous friction in the liquid layer between the cornea and lens. The effect of variables such as base curves, lens diameters and thickness of tear film layer were illustrated by the computer simulation of the derived program. The time required for the lens to return to the original position increases as the liquid layer thickness increases and it decreases as the diameter of lens increases. With the certain value of base curve the time interval is found to be minimum. The free vibrations of lenses were also simulated varying the parameters such as base curve, diameter, layer thickness. The resonant frequencies are inversely proportional to the liquid layer thickness and it increases as the lens diameter increases. The resonant frequency of lens has a maximum when the diameter is of certain value. If the external impulse or force of the same frequency as the natural frequency of contact lens acted on the cornea in vivo it may cause an excessive movement and thus it might cause the distortion 10 the lens or be pulled off the eye.

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Relation between Autogenous Shrinkage of Concrete and Relative Humidity, Capillary Pressure, Surface Energy in Pore (공극 내 상대습도, 모세관압력, 표면에너지 변화에 따른 콘크리트 자기수축)

  • Lee, Chang-Soo;Park, Jong-Hyok
    • Journal of the Korea Concrete Institute
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    • v.20 no.2
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    • pp.131-138
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    • 2008
  • Humidity and strain were estimated for understanding the relation between humidity change by self-desiccation and shrinkage in high-performance concrete with low water binder ratio. Internal humidity change and shrinkage strain were about 10%, 4% and $320\times10^{-6}$, $120\times10^{-6}$ respectively on concrete with water binder ratio 0.3, 0.4 and from the results, humidity change and shrinkage represented the strong linear relation regardless of mixture. For specifying the relation on internal humidity change and autogenous shrinkage strain, shrinkage model was established which is driven by capillary pressure in pore water and surface energy in hydrates on the assumption of a single network and extended meniscus in pore system of concrete. This model and experimental results had a similar tendency so it would be concluded that the internal humidity change by self-desiccation in HPC originated in small pores less than 20 nm, therefore controlling plan on autogenous shrinkage might be focused on surface tension of water and degree of saturation in small pore.

Modeling the Influence of Gas Pressure on Droplet Impact Using a Coupled Gas/liquid Boundary Element Method

  • Park, Hong-Bok;Yoon, Sam S.;Jepsen Richard A.;Heister Stephen D.
    • Journal of ILASS-Korea
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    • v.11 no.2
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    • pp.89-97
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    • 2006
  • An inviscid axisymmetric model capable of predicting droplet bouncing and the detailed pre-impact motion, influenced by the ambient pressure, has been developed using boundary element method (BEM). Because most droplet impact simulations of previous studies assumed that a droplet was already in contact with the impacting substrate at the simulation start, the previous simulations could not accurately describe the effect of the gas compressed between a failing droplet and the impacting substrate. To properly account for the surrounding gas effect, an effect is made to release a droplet from a certain height. High gas pressures are computationally observed in the region between the droplet and the impact surface at instances just prior to impact. The current simulation shows that the droplet retains its spherical shape when the surface tension energy is dominant over the dissipative energy. When increasing the Weber number, the droplet surface structure is highly deformed due to the appearance of the capillary waves and, consequently, a pyramidal surface structure is formed; this phenomenon was verified with our experiment. Parametric studies using our model include the pre-impact behavior which varies as a function of the Weber number and the surrounding gas pressure.

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