• 제목/요약/키워드: Cancer distribution

검색결과 1,056건 처리시간 0.029초

Human Papillomavirus Genotypes and Cervical Cancer in Northeast Thailand

  • Natphopsuk, Sitakan;Settheetham-Ishida, Wannapa;Pientong, Chamsai;Sinawat, Supat;Yuenyao, Pissamai;Ishida, Takafumi;Settheetham, Dariwan
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권11호
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    • pp.6961-6964
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    • 2013
  • Human papillomavirus (HPV) is a major cause of cervical cancer. More than 100 HPV genotypes have been identified; however the distribution varies geographically and according to ethnicity. The purpose of this study was to investigate the prevalence and distribution of HPV subtypes among Northeast Thai women. Subjects included 198 cases of SCCA and 198 age-matched, healthy controls. HPV-DNA was amplified by PCR using the consensus primers GP5+/6+ system followed by reverse line blot hybridization genotyping. The prevalence of high-risk HPV infection was 21 (10.1%) and 152 (76.8%) in the controls and in the cases, respectively. High-risk HPV significantly increased the risk for cervical cancer with an OR of 42.4 (95%CI: 22.4-81.4, p<0.001) and an adjusted OR of 40.7-fold (95%CI: 21.5-76.8, p <0.001). HPV-16 was the most prevalent HPV type in the SCCA (56.2%) followed by HPV-58 (17.8%) and HPV-18 (13.6%); whereas HPV-58 (46.4%) was a prominent genotype in the controls followed by HPV-16 (39.3%) and unidentified HPV types (25.0%). These findings indicate that HPV infection remains a critical risk factor for SCCA; particularly, HPV-16, HPV-58 and HPV-18. In order to eradicate cervical cancer, sustained health education, promoted use of prophylactics and a HPV-58 vaccine should be introduced in this region.

암 환자의 대체요법 이용에 관한 연구 (A Study on Use of Alternative Therapy in Cancer)

  • 박형숙;이윤미
    • 재활간호학회지
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    • 제3권2호
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    • pp.212-227
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    • 2000
  • The purpose of this study was to investigate the patterns of alternative therapy and to describe the characteristics of cancer patients used alternative therapy. The sample of this study were 232 consisted of cancer patients who visited at Pusan National University Hospital, Dong-a, Kosin University Hospital. The data were gathered from August, 1 to October, 30 1999 and analyzed by using SPSSWIN program for frequency, percentile and $X^2$-test. The important results of this study are as follows. 1. In population-sociological characteristics, sexual distribution showed female 52.6%, and the male 47.4%, age distribution showed that more than 60year old group are most as 31.5%. 2. In the disease characteristics, colon and rectal cancer patients were most as 19.0%. In the type of pain, the most of subjects were "dully pain" as 25.4%. In the pain level, 134 subjects complained pain, mean maximal pain score was $7.3{\pm}2.29$ in 10 points rating scale. 3. 132 patients (56.9%) among 232 cancer patients had used alternative therapy. The most common type of alternative therapy was dietary and nutritional therapy 44%, the place of use. home 43.2%, duration, less than 3 months, 56.8%. The most common motive was a recommendation by friends or family. The degree of satisfaction after the use of alternative therapy was high for 22.0%. 4. In the relation between general characteristic and utilization of alternative therapy, the only living area was showed a significant statistical differance($X^2$ = 4.070, P= .044). also in the relation between disease characteristic and utilization of alternative therapy, morbidity periods, the size of higher pain, the type of treatment were showed a significant statistical differance($X^2$= 7.964, 7.303, 3.565, P=.044, .026, .042). In conclusions, these findings indicate that cancer patients use various complementary and in alternative therapy. therefore, suggested that medical doctors or nurses verify the true effects or side-effects from the most common complementary or alternative therapies through experiments.

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Statistical Assessment on Cancer Risks of Ionizing Radiation and Smoking Based on Poisson Models

  • Tomita, Makoto;Otake, Masanori;Moon, Sung-Ho
    • Journal of the Korean Data and Information Science Society
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    • 제17권2호
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    • pp.581-598
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    • 2006
  • In many epidemiological and medical studies, a number of cancer mortalities in categorical classification may be considered as having Poisson distribution with person-years at risk depending upon time. The cancer mortalities have been evaluated by additive or multiplicative models with regard to background and excess risks based on several covariances such as sex, age at the time of bombings, time at exposure, or ionizing radiation, cigarette smoking habits, duration of smoking habits, etc. An interest herein is to examine an additive, synergistic, or antagonistic relationship between radiation exposures and cigarette smoking habits for cancer mortalities. The results revealed a highly significant antagonistic in uence for cancer mortalities from all non-hematologic findings, lung and respiratory system with negative interaction between radiation exposures and cigarette smoking amounts.

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MC-50 싸이클로트론을 이용한 In-111 제법 개발 (The Production of Carrier Free Indium-111 with MC-50 Cyclotron)

  • 전권수;서용섭;양승대;채종서;지광수;이종두
    • 대한방사선기술학회지:방사선기술과학
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    • 제13권2호
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    • pp.43-49
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    • 1990
  • [ $^{111}$ ]In has wide applications in nuclear medicine for labelling and in-vivo distribution studies. A method is developed for the production of carrier free $^{111}$In using the reaction $^{nat.}Cd(p,\;xn)$ $^{111}$In with MC-50 cyclotron. Carrier free $^{111}$In was separated from the irradiated metallic cadmium by liquid-liquid extraction and cation exchange chromatography. The yield of $^{111}$In at EOB is $0.8mCi/{mu}\;Ahr$ and the nuclidic purity is over 99%. $^{111}In-DTPA\;and\;^{111}In-bleomycin$ were prepared for medical study.

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전이성폐종양에 대한 고찰 (Clinical Review of Metastatic Lung Tumor)

  • 김진식;손말현;서정회
    • Journal of Chest Surgery
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    • 제7권1호
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    • pp.37-46
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    • 1974
  • 52 cases of metastatic lung tumor, including 22 [42.3%] choriocarcinoma., 13[25%] liver cancer, 6 [7.5%] stomach cancer, 2 bone tumor, etc, were reviewed at Busan National University Hospital, during a 5 year period ending with 1974. The age distribution of metastatic lung tumor were same in second decade to 5th decade. The most common appearances of roentgenograms of metastatic lung tumor were that of multinodular [42.3%], diffuse acinar [21.1%],infiltrative or pneumonic[21.1%], solitary lesion [9.6%] and diffuse micronodular [5.7%]. The metastatic lesions originated from choriocarcinoma revealed multinodular and acinar in roentgenogram, and the lesions originated from liver and stomach cancer revealed infiltrative and acinar. In our series, the positive hilar lymph node enlargement was encountered in 12 cases, of which 4 were in liver cancer and 3 were in stomach cancer. Pleural effusion was also encountered in 5 cases, of which 3 were in liver cancer. The treatment of this series was almost conservative except of 2 cases of pulmonary resection, and the reason of this limited cases of surgical treatment was seemed due to the delayed direction of metastasis to lung beyond the proper indication of surgery.

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Estimation of Denominators- a New Approach for Calculating of Various Rates in Cancer Registries

  • Haroon, A.S.;Gupta, S.M.;Tyagi, B.B.;Farhat, J.
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권7호
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    • pp.3229-3232
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    • 2012
  • In this study, cancer incidence data were assessed to provide various rates of five year age groups for a given year, lying between two census years. The individual exponential growth rate method is most useful in both population-based and non-population cased cancer registries in India to estimate the population by five yearly age groups and also find the rates of crude rates, age standard rates and cumulative rates. This method has been shown to endure from bias and often results sacrificing the overall growth rate and correction factor must be needful in five year age group population to maintain it. A second method, the difference distribution method is also able to maintain the overall growth rate and overcome the bias in estimation of five yearly age group populations. From this point of view these methods serving a new technique for population estimation by five yearly age groups for inter census years.

배양한 자궁암세포의 염색체 구성에 관하여 (On the Chromosome Distribution of Uterine Carcinoma in Culture)

  • Kang, Yung-Sun;Kim, Suk-Whan;Park, Eun-Ho
    • 한국동물학회지
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    • 제15권1호
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    • pp.15-21
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    • 1972
  • 두 케이스의 자궁암 조직을 배양하여 그들의 염색체를 구룹별로 분석한 결과는 아래와 같다. 1. 종족세포의 염색체수가 한 경우는 46이었고, 다른 한 환자에서는 60으로서 저3배성을 나타내었다. 2. 후자의 핵형을 구룹별로 분석한 결과, 구룹간의 염색체 분포는 non-random인 것으로 나타났다.

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The C609T (Pro187Ser) Null Polymorphism of the NQO1 Gene Contributes Significantly to Breast Cancer Susceptibility in North Indian Populations: a Case Control Study

  • Yadav, Prasant;Mir, Rashid;Nandi, Kajal;Javid, Jamsheed;Masroor, Mirza;Ahmad, Imtiyaz;Zuberi, Mariyam;Kaza, RCM;Jain, SK;Khurana, Nita;Ray, Prakash Chandra;Saxena, Alpana
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권3호
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    • pp.1215-1219
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    • 2016
  • Background: Worldwide, breast cancer is the most common cancer among women and is a leading cause of cancer death. In the present study, we investigated the NQO1 C609T genotypic and allelic distribution in north Indian breast cancer patients. Materials and Methods: The genotypic distribution of the NQ01 C609T polymorphism was assessed in 100 invasive ductal carcinoma (IDC) breast cancer patients and 100 healthy controls using allele specific PCR (AS-PCR). Results: A lower frequency of the CC genotype was found in breast cancer patients (24%) than in the controls. On the other hand, TT genotype frequency was also found to be higher in female healthy controls (32%) than the female breast cancer patients (20%). The frequencies of all three genotypes CC, CT, TT in patients were 24%, 56% and 20% and in healthy controls 50%, 22% and 32% respectively. We did not find any significant correlation between the NQO1 C609T polymorphism and age group, grading, menopausal status and distant metastasis. A less significant association was found between the NQ01 C609T polymorphism and the stage of breast cancer (X2=5.931, P=0.05). Conclusions: The present study shows a strong association between NQO1 C609T polymorphism with the breast cancer risk in the north Indian breast cancer patients so that possible use as a risk factor should be further expel.