• 약학회지
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• 제39권1호
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• pp.61-67
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• 1995

PVC membrane electrodes based on the lipophilic neutral carrier, dibenzo-18-crown-6, cyclic oligomers of teit-butylphenol-formaidehyde condensates, calix[4]arenes as the active sensors for verapamil have been prepared and tested in a variety of plasticizers. At pH 5.0, the electrode exhibits a Nernstian response in the range of 10$^{-2}$~5$\times$10$^{-5}$ M verapamil with a slope of 49.1$\pm$0.5mV per concentration decade. The electrode constructed in this work can be used continuously for at least 1 month before any damage to the membrane occurs. And the analyses of the local anesthetic amine, which are good to select a specific compound in a mixed solution, were also accomplished by using of another neutral carrier, a DB18C6, for comparing with calix[4]arene.

• Bulletin of the Korean Chemical Society
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• 제21권8호
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• pp.813-816
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• 2000

The synthesis of bisphenol A-derived calixarenes has been studied by changing the protecting group of the phe-nol moiety and reaction conditions. Depending on the protecting groups,the corresponding calix[6,7,8]arenes are obtained in different rat ios. For example, whcn mono-p-tert-butyldimethylsilyl-protected bisphenol A is treated with paraformaldehyde and a catalytic amount ofaqueous KOH in refluxing p-xylene with a Dean-Stark water collector for 36 h, the corresponding calix[8]arene, calix[7]arene, and calix[6]arene are producedand separated in the ratio of about 3 : 2 : l and with overall 63% yield. The calixarenes are characterized by NMR spectroscopy and mass analysis. The X-raycrystal structure of the calix[8]arene shows a pleated loop confor-mation, stabilized by intramoIecular hydrogen bonding between the inner phenolic hydroxy groups.

• Bulletin of the Korean Chemical Society
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• 제15권9호
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• pp.791-795
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• 1994

1,3-Dimethyl and dipropyl ethers of p-t-butylcalix[4]arene and calix[4]arenes have been converted to the corresponding diesters, acetate and propionate, and their conformations are inferred based on the $^1H$ and $^{13}C$ NMR spectra. The presence of t-butyl groups is effective in maintaining the cone conformation on derivatization.

• Bulletin of the Korean Chemical Society
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• 제29권1호
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• pp.221-224
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• 2008

• 전기화학회지
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• 제3권2호
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• pp.69-71
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• 2000

카르복시산과 이황하물 다리를 가지며 산화환원 활성이 있는 칼릭스[4]아렌을 합성하였고 그것이 은과 금 표면 위에 자발적으로 흡착하는 것을 관찰하였다. 칼릭스[4]아렌은 특이한 구조 때문에 수용액에서 알칼리 토금속이온에 선택적인 친화력을 보인다 한편 둥그런 이온 수용체를 전극 위에 고정시켰을 때 금속 이온을 포획하는 것을 전압전류법 및 분광학적인 연구를 통해 확인하였다. 아울러 EDTA와 같은 강한 킬레이트제를 이용하여 이온을 가역적으로 제거할 수 있음을 보였다.

• 대한화학회지
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• 제41권7호
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• pp.366-370
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• 1997

• Bulletin of the Korean Chemical Society
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• 제18권9호
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• pp.1014-1017
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• 1997

1,3-Dipropyloxycalix[4]arene dibenzocrown ethers were synthesized in the fixed 1,3-alternate conformation by the reaction of 1,3-dipropyloxycalix[4]arenes with a dibenzo dimesylates. Complexation toward alkali metal ions using ISEs showed a high cesium selectivity. Conformational flexibility of the corresponding 1,3-alternate calixcrown ether (4) with respect to the NMR time scale is found to depend on the temperature and polarity of the NMR solvent.

• Bulletin of the Korean Chemical Society
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• 제18권10호
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• pp.1050-1052
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• 1997

The complexes M(CO)4-1,2-(PPh2)2-1,2-C2B10H10 (M=Cr 2a, Mo 2b, W 2c) have been prepared in good yields from readily available bis-diphenylphosphino-o-carboranyl ligand, closo-1,2-(PPh2)2-1,2-C2B10H10 (1), by direct reaction with Group Ⅵ metal carbonyls. The infrared spectra of the complexes indicate that there is an octahedral disposition of chelate bis-diphenylphosphino-o-carboranyl ligand around the metal atom. The crystal structure of 2a was determined by X-ray diffraction. Complex 2a crystallizes in the monoclinic space group P21/n with cell parameters a = 12.2360(7), b = 17.156(1), c = 16.2040(6) Å, V = 3354.1(3) Å3, and Z =4. Of the reflections measured a total of 2514 unique reflections with F2 > 3σ(F2) was used during subsequent structure refinement. Refinement converged to R1 = 0.066 and R2 = 0.071. Structural studies showed that the chromium atom had a slightly distorted pseudo-octahedral configuration about the metal center with two phosphine groups of o-carborane occupying the equatorial plane cis-orientation to each other. These metal carbonyl complexes are rapidly converted to the corresponding metal carbene complexes, [(CO)3M=C(OCH3)(CH3)]-1,2-(PPh2)2-1,2-C2B10H10 (M= Cr 3a, Mo 3b, W 3c), via alkylation with methyllithium followed by O-methylation with CF3SO3CH3.

• Bulletin of the Korean Chemical Society
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• 제32권4호
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• pp.1143-1145
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• 2011

The synthesis of novel iminecalix[4]arenes and further modification thereafter is described using a synthetic strategy. The reaction of the benzaldehyde derivatives with tetraamine functions on the calix[4]arene easily afforded the pure compounds in 92.4-95.7% yields, regardless of the effect of the substituents on the benzaldehyde derivatives. These compounds were stable under the conditions to obtain their analogue dialkylated in the narrow rim, with 83.2-89.9% yields. Characterization of the newly synthesized iminecalix[4]arene derivatives by spectroscopic methods revealed that all compounds are in the cone conformations.