• Title/Summary/Keyword: Cadimium

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Effects of Cadmium on Superoxide Radical Superoxide Dismutase, Catalase and ATPase Activit in liver, Kidney and Testicle of Rats in Vitro and in Vivo (시험관내 및 생체내로 투여한 카드뮴이 랏트의 간, 신 및 고환조직 내의 Superoxide Radical, Superoxide Dismutase, Catalase 및 ATPase 활성도에 미치는 영향)

  • Kim, Sung-Moo;Chung, Kyou-Chull
    • Journal of Preventive Medicine and Public Health
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    • v.23 no.4 s.32
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    • pp.371-390
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    • 1990
  • Production of free radicals of superoxide anion in tissues by cadmium, activities of superoxide dismutase and catalase to protect tissue damages caused by the free radicals and ATPase that plays an important role in energy metabolism at cellular level were investigated. Experiments in vivo were conducted with liver, kidney and testicle tissue homogenates of rats adding $0.05{\sim}0.50mM$ cadmium chloride, and in vivo experiments administering single dose of 5 mg of cadmium/kg of body weight in 0.1% cadmium chloride solution intraperitoneally 48 hours prior to evisceration. Production of superoxide radicals in liver and testicle increased with addition of cadmium in vitro, but not in kidney. In vivo experiments, however, superoxide radicals slightly increased in liver and kidney but not in testicle. Superoxide dismutase (Cu, Zn-SOD and Mn-SOD), catalase and ATPase (total, $Mg^{++}-\;&\;Na^+,\;K^+-$) activity decreased in the presence of cadimium in dose dependent manner. Reduction of these enzyme activities varied not only with dosage of cadmium but also with type of tissue and between in vitro and in vivo experiment.

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Adsorption Characterization of Cd by Activated Carbon containing Hydroxyapatite using Response Surface Methodology (RSM) (반응표면분석법을 이용한 Hydroxyapatite 첨가 활성탄에서의 Cd 흡착특성에 관한 연구)

  • An, Sang-Woo;Yoo, Ji-Young;Choi, Jae-Young;Park, Jae-Woo
    • Journal of Korean Society on Water Environment
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    • v.25 no.6
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    • pp.943-950
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    • 2009
  • Cadmium (Cd) adsorption onto the activated carbon containing hydroxyapatite (HAP) was investigated in batch experiments and response surface methodology (RSM) using the Box-Behnken methods were applied to the experimental results. Cd adsorption with different HAP mass ratio of from 10% to 30%. With more HAP, Cd was more adsorbed. These results suggest that the higher HAP mass causes an increase of the ion exchange potential of the HAP sorbent. Equilibrium experimental results from Cd adsorption was fitted to Langmuir and Freundlich isotherm models. Cd adsorption on HAP sorbent were found to follow the Freundlich isotherm model well in the initial adsorbate concentration range. Also, Cd adsorption was a function of the HAP mass ratio ($x_1$), initial Cd concentration ($x_2$), and initial pH ($x_3$) from the application of the RSM. Statistical results showed the order of significance of the independent variables to be initial Cd concentration > HAP mass ratio > initial pH.

Sister Chromatid Exchanges(SCE) in Cultured Human Lymphocytes Induced by Cadmium, Selenium and Zinc (배양임파구에서 카드뮴, 셀레늄 및 아연 투여가 자매염색분체교환에 미치는 영향)

  • 이연경;조영채
    • Journal of Environmental Health Sciences
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    • v.23 no.4
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    • pp.26-32
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    • 1997
  • To evaluate the cytogenetic toxicity, of cadmium and the reducing effect of selenium or zinc on cadmium toxicity, the induction of SCEs in cultured human lymphocytes by the concentraion of 0.5 $\mu$M to 16.0 $\mu$M of cadmium chloride and those of cadmium chloride combined with sodium selenite or zinc chloride 1.2 $\mu$M, respectively was investigated. The induction of SCEs by cadmium chloride in the range of 0.5 $\mu$M to 16.0 $\mu$M increased in a dose-dependent manner. A notable increase in SCEs by sodium selenite as well as zinc chloride was also observed. However, the frequency of SCEs by cadmium chloride was inhibited by the simultaneous addition of sodium selenite and zinc chloride 1.2 $\mu$M, respectively. The mitotic index significantly decreased in higher concentration of cadmium chloride but not was significantly different in any concentration of cadmium chloride with the simultaneous addition of sodium selenite or zinc chloride. The results showed that the decreased additive SCE effect was observed when induced by the combined treatment which could suggest that sodium selenite and zinc chloride have a protective effect on cadmium chloride.

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Effects of Green Tea Catechin on Cadimium Accumulation in Chronic Cadmium Poisoned Rats (만성 카드뮴 중독 쥐에서 카드뮴 축적에 미치는 녹차 Catechin의 영향)

  • Choi, Jeong-Hwa;Rhee, Soon-Jae
    • Journal of Nutrition and Health
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    • v.34 no.4
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    • pp.384-392
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    • 2001
  • The purpose of this study was to investigate the effects of green tea catechin on the cadmium accumulation in body, cadmium excretion and detoxification functions in chronic cadmium poisoned rats. Sprague-Dawley male rats weighing 100$\pm$10g were randomly assigned to one normal group and three cadmium poisoned groups. Cadmium groups were classified to catechin free diet (Cd-0C group), 0.25% catechin diet(Cd-0.25C group) and 0.5% catechin diet(Cd-0.5C group) according to the levels of catechin supplement. Animals were maintained on 0, 0.25 and 0.5% catechin diets for 20 weeks and simultaneously administered 50ppm Cd(sup)2+ dissolved in the drinking water. Body weight, food intakes and food efficiency ratio in Cd-0C group was lower than the normal group. The accumulation of cadmium in rat liver, kidney, and blood was reduced by catechin supplementation. The excretion of cadmium in urine and feces was increased by catechin supplementation. The metallothionein(MT) contents in liver and kidney were increased in all cadmium groups compared with that of normal group. The ratios of cadmium absorption and retention ratios were significantly decreased in catechin supplementation groups. Accordingly, catechin supplementation resulted to an excretion of cadmium in urine and feces and a lowered accumulation of cadmium in liver and kidney by increasing methallothionein synthesis that led to the significant decrease in cadmium absorption and retention ratios.(Korean J Nutrition 34(4) : 384~392, 2001)

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Heavy Metals in Ambient Air at Shinchon Area in Seoul (도시 대기중 중금속에 관한 연구 -서울시 신촌지역을 중심으로-)

  • Chung, Yong;Jang, Jae-Yeon;Chu, Ui-Jo
    • Journal of Korean Society for Atmospheric Environment
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    • v.3 no.2
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    • pp.18-26
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    • 1987
  • In order to investigate the character of air pollution by heavy metals and to elucidate the possible sources in Seoul city, this study was performed to measure the concentrations of heavy metals of total suspended particulate and air pollutants such as $SO_2, NO_2, CO, CH_4$, Non-methane hydrocarbon, ozone at the residential-traffic area (shinchon dong) in January and February, 1986. The results are as follows: 1. $SO_2$ and TSP concentration were 135ppb and 167 $\mug/m^3$ in average, respectively. 2. While concentrations of heavy metals such as Fe, Cu, Pb in the ambient air seems gradually decreasing annually, Ni compound has been shown the tendency of increasing. 3. Among heavy metals in TSP analysed, the iron was detected at the highest level, 0.905% and the cadimium was the lowest 0.004% in average, respectively. 4. V, Fe and Zn compounds in air were observed to be highly correlated with their correlation coefficients(r) higher than 0.7. Pb compound was highly correlated to the levels of Zn and Fe, however relatively less correlated to V compound. 5. Among concentrations of heavy metals in the particulates, V and Ni compounds were highly correlated with coefficient(r) of 0.8587; the cause might be imagined by the fact of releasing from combustion of fuel oil. Fe, Pb and Zn compounds were highly correlated $SO_2$ concentration. It might be explained that they were released by combustion of coal. 6. The level of $SO_2$ was highly correlated to most of heavy metals: especially correlation coefficient(r) to Pb compound was 0.9081. Pb compound was also highly correlated to NO, CO and TSP. TSP showed higher correlation to Pb and Cd compounds than to V and Ni compounds. It might be assumed that particulate was mainly produced by combusting coal from space heating and by exhausting gasoline and diesel oil from transportation rather than by burning fuel oil.

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Studies on the Trace Elements, Heavy Metals and Organic acids Content of Edible Mushrooms (버섯류의 미양금속, 중금속 및 유기산 함양에 관한 연구)

  • 허선행
    • Journal of environmental and Sanitary engineering
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    • v.7 no.1
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    • pp.57-66
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    • 1992
  • To investigate on the element content of twelve edible mushrooms and Aloe arborescent, i.e., Lentinus edodes, Ganoderma lucidum (culturing in wood and soil), Tricholoma matsutake, Agaricus auricula-Jude (produced in Korea and China), sarcodon asparatus, Pleurotus ostreatus, Coriolus bisporus, Cyrophora esculenta, Auricularia auricula-Jude (produced in Korea and China), Sarcodon asparatus, Pleurotus ostreatus, Coriolus rersicolor, Smilax rotundifolia and Aloe arborescenstyl were analyzed by Atomic absorption spectrometer. The obtained results were summarized as follows : 1. Potassium, sodium, magnesium and iron content for the most part samples were in large quantities, especi phosphorus content of those was highest ammount for the all samples. 2. Sodium content f·as much ammount in the Lentinus edodes(39 mg, and Ganoderma lucidum(20 mg) , Culturing in wood and soil, while potassium was very high ammount in the Aloe arborescens and other samples. Mush ammount of magnesium as compared with others was Lentinus edodes(144 mg) , Ganoderma lucidum(128 mg), Aloe arborescens(50 mg) and Pleurotus ostreatus (60 mg) . 3, Phosphorus content of Lentinus edodes, Gyrophora esculenta, Auricularia polytricha and Agaricus bisporus was much ammount while iron content of all samples equality higher ammount. Sodium content of Aloe arborescens was not analyzed out for almost all, its potassium(82 mg), magnesium(50 mg) and iron(18 mg) content comparatively higher quentity than others nllnerals and phosphorus volume (4.9 mg) as compared with others, was conspicuously lower detect. 4. Cadimium and lead content of harmful metal element were detected on trace quantity for the most part samples. 5. Organic acids of samples i.e., Lentinus edodes, Agaricus bisporus, Pleuritus ostreatus and Ganoderma lucidum were Citrate, Malate, Fumalate, Succinate, Oxalate, Acetate, Lactate, and Tartarate and Citrate, Malate and Fumarate contents were higher amount remarkbly than other organic acids. Tartarate content was trace amount.

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Evaluation of Image Quality by Using Various Detector Materials according to Density : Monte Carlo Simulation Study (몬테카를로 시뮬레이션 기반 밀도에 따른 다양한 검출기 물질을 적용한 획득 영상 평가)

  • LEE, Na-Num;Choi, Da-Som;Lee, Ji-Su;Park, Chan-Rok
    • Journal of radiological science and technology
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    • v.44 no.5
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    • pp.459-464
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    • 2021
  • The detector performance is important role in acquiring the gamma rays from patients. Among parameters of detector performances, there is density, which relates to respond to gamma rays. Therefore, we confirm the detection efficiency according to various detector materials based on the density parameter using GATE (geant4 application for emission tomography) simulation tool. The NaI (density: 3.67 g/cm3), CZT (Cadimium Zinc Telluride) (density: 5.80 g/cm3), CdTe (Cadmium Telluride) (5.85 g/cm3), and GAGG (Gadoinium Aluminum Gallium Garnet) (density g/cm3) were used as detector materials. In addition, the point source and quadrant bar phantom, which is modeled for 0.5, 1.0, 1.5, and 2.0 mm thicknesses, were modeled to confirm the quatitative analysis using sensitivity (cps/MBq) and the full width at half maximum (FWHM, mm) at the 2.0 mm bar thickness containing visual evaluation. Based on the results, the sensitivity for NaI, CZT, CdTe, and GAGG detector materials were 0.12, 0.15, 0.16, and 0.18 cps/MBq. In addition, the FWHM for quadrant bar phantom in the 2.0 mm bar thickness is 3.72, 3.69, 3.70, and 3.73 mm for NaI, CZT, CdTe, and GAGG materials, respectively. Compared with performance of detector materials according to density, the high density can improve detection efficiency in terms of sensitivity and mean count. Among these detector materials, the GAGG material is efficient for detection of gamma rays.

A Study for Analysis of Image Quality Based on the CZT and NaI Detector according to Physical Change in Monte Carlo Simulation (CZT와 NaI 검출기 물질 기반 물리적 변화에 따른 영상의 질 분석에 관한 연구: 몬테카를로 시뮬레이션)

  • Ko, Hye-Rim;Yoo, Yu-Ri;Park, Chan-Rok
    • Journal of the Korean Society of Radiology
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    • v.15 no.5
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    • pp.741-748
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    • 2021
  • In this study, we evaluated image quality by changing collimator length and detector thickness using the Geant4 Application for Tomographic Emission (GATE) simulation tool. The gamma camera based on the Cadimium Zinc Telluride (CZT) and NaI detectors is modeled. In addition the images were acquired by setting 1, 2, 3, 4, 5, and 6 cm collimator length and 1, 3, 5, and 7 mm detector thickness using point source and phantom, which is designed by each diameter (4.45, 3.80, 3.15, 2.55 mm) with 447, 382, 317, and 256 Bq. The sensitivity (cps/MBq) for point source, and signal to noise ratio (SNR) and profile for phantom at the 4.45 mm by drwan the region of interests were used for quantitative analysis. Based on the results, the sensitivity according to collimator length is 2.3 ~ 48.6 cps/MBq for CZT detector, and 1.8 ~ 43.9 cps/MBq for NaI detector. The SNR using phantom is 3.6~9.8 for CZT detector, and 2.9~9.5 for NaI detector. As the collimator length is increased, the image resolution is also improved according to profile results based on the CZT and NaI detector. In addition, the senistivity for detector thickness is 0.04 ~ 0.12 cps/MBq for CZT detector, and 0.03 ~ 0.11 cps/MBq. The SNR using phnatom is 7.3~9.8 count for CZT detector, and 5.9~9.5 for NaI detector. As the detector thickness is increased, the image resolution is decreased according to profile results based on the CZT and NaI detector due to scatter ray. In conclusion, we need to set the geometric material such as detector and collimator to acuquire suitable image quality in nuclear medicine.

Kinetics and Equilibrium Adsorption Studies of Cd Adsorption by the Activated Carbon Containing Hydroxyapatite (Hydroxyapatite 첨가 활성탄을 이용한 Cd의 동역학적 흡착과 흡착평형에 관한 연구)

  • An, Sangwoo;Choi, Jaeyoung;Park, Jaewoo
    • Journal of the Korean GEO-environmental Society
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    • v.11 no.1
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    • pp.45-51
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    • 2010
  • Cadmium (Cd) adsorption by the activated carbon containing hydroxyapatite (HAP) was investigated. Cd adsorption with different HAP mass ranged from 10% to 30%. With more HAP, more Cd was adsorbed. These results suggest that the higher HAP dose causes an increase of the ion exchange potential in HAP sorbent. Kinetics and equilibrium studies were investigated in series of batch adsorption experiments. Langmuir and Freundlich isotherm models were fit to the equilibrium data and Cd adsorption on HAP sorbent were found to follow the Freundlich isotherm model well in the initial adsorbate concentration range. The simple kinetic model, the pseudo first order kinetic model and the pseudo second order kinetic model, were used to investigate the adsorption. The adsorption reaction of Cd followed the pseudo second order kinetic model, and the adsorption pseudo second order kinetic constants ($k_2$) increased with increasing initial HAP amounts onto activated carbon. Also, intraparticle diffusion model was used to investigate the adsorption mechanism between adsorbate and adsorbent in the aqueous phase. Surface adsorption reaction and intraparticle diffusion occur simultaneously Cd adsorption mechanism from aqueous phase in this study.

Studies on Inorganic Components of Korean Wild Edible Mushrooms - Trace Mineral Elements of Armillariella Mella, Hygrophorous russula, Armillariella tabescens, Lepista nuda and lepista sordida, Hygrocybe conica. - (한국산 야생(野生) 식용버섯의 무기성분에 관한 연구 - 뽕나무버섯, 뽕나무버섯부치, 벚꽃버섯, 민자주방망이버섯, 자주방망이버섯아재비, 붉은산무명버섯의 미량금속원소 -)

  • Park, Wan-Hee
    • The Korean Journal of Mycology
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    • v.21 no.4
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    • pp.273-278
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    • 1993
  • In order to determine of trace mineral elements of wild edible mushrooms in Korea, the dried carpophores of Armillariella mella(Vahl.ex Fr.) karst., Armillariella tabescens(Scop.) Sing., Lepista nuda(Bull.ex Fr.) Cooke and Lepista sordida(Schum.ex Fr.) Sing., Hygrophorus russula (Schaeff.ex Fr.) Qu'el., Hygrocybe conica(Scop.ex Fr.) Kummur were incinerated and analyzed by an atom adsorption spectrophotometry. The six mushrooms contained ubiquitously potassium, iron, zinc, sodium, manganase, copper and calsium in that order, and the content of potassium was the highest than other inorganic components and the content of zinc in Hygrocybe conica was especially the most than the other five mushrooms. Total contents of inorganic components(except Cd) were universally the highest in Hygrocybe conica than other five mushrooms, and decrease in order Hygrophorus russula, lepista nuda, lepista sordida, Aarmillariella mella and Armillariella tabescens. Calsium was not present in Amillariella mella and lepista nuda, and copper not in Hygro­cybe conica, and content of cadimium in Hygrophorus russula and Hygrocybe conica were trace.

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