• 제목/요약/키워드: CY&P model

검색결과 12건 처리시간 0.02초

수산자원량 추정을 위한 생물경제 모델의 적합성평가 (Determining Appropriate Bioeconomic Models for Stock Assessment of Aquatic Resources)

  • 표희동
    • 수산경영론집
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    • 제33권2호
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    • pp.75-98
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    • 2002
  • As a contribution to developing fishery stock assessment, optimum sustainable yield and its international standards such as MSY, MEY, and dynamic MEY for six recommended fisheries are developed using bio-economic models. For selecting the appropriate model, five models - Schaefer, Schnute, Walters and Hilborn, Fox, and CY&P models are tested in effort and catch data of six species. Surprisingly all the models except the CY&P model failed to satisfy statistical standards such as goodness-of-fitness and reliability. Generally, the CY&P model holds good fitness and statistically significant level for all of six fisheries. However, the CY&P model for squid, where the intrinsic growth rate is high, could not explain MSY, MEY, and dynamic MEY appropriately. This study makes a contribution to develop the modified model for the intrinsic growth rate of 1. The reformulated model represents the results reasonably even though the estimated equation has not good fitness. Although most of the CY&P models appear to have good fits and validated results for some cases, these models also seem to be quite sensitive to parameters which means a more stable model should be developed and data should carefully be handled. In particular biological and technical interactions such as multispecies, predator prey relationship, age structure and mortality should be taken into account. In addition, economic factors and fishing efforts such as price, cost, technical change and a reasonable function of fishing input should simultaneously be considered.

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Molecular characterization and docking dynamics simulation prediction of cytosolic OASTL switch cysteine and mimosine expression in Leucaena leucocephala

  • Harun-Ur-Rashid, Md.;Masakazu, Fukuta;Amzad Hossain, Md.;Oku, Hirosuke;Iwasaki, Hironori;Oogai, Shigeki;Anai, Toyoaki
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 2017년도 9th Asian Crop Science Association conference
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    • pp.36-36
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    • 2017
  • Out of twenty common protein amino acids, there are many kinds of non protein amino acids (NPAAs) that exist as secondary metabolites and exert ecological functions in plants. Mimosine (Mim), one of those NPAAs derived from L. leucocephala acts as an iron chelator and reversely block mammalian cell cycle at G1/S phases. Cysteine (Cys) is decisive for protein and glutathione that acts as an indispensable sulfur grantor for methionine and many other sulfur-containing secondary products. Cys biosynthesis includes consecutive two steps using two enzymes-serine acetyl transferase (SAT) and O-acetylserine (thiol)lyase (OASTL) and appeared in plant cytosol, chloroplast, and mitochondria. In the first step, the acetylation of the ${\beta}$-hydroxyl of L-serine by acetyl-CoA in the existence of SAT and finally, OASTL triggers ${\alpha}$, ${\beta}$-elimination of acetate from OAS and bind $H_2S$ to catalyze the synthesis of Cys. Mimosine synthase, one of the isozymes of the OASTLs, is able to synthesize Mim with 3-hydroxy-4-pyridone (3H4P) instead of $H_2S$ for Cys in the last step. Thus, the aim of this study was to clone and characterize the cytosolic (Cy) OASTL gene from L. leucocephala, express the recombinant OASTL in Escherichia coli, purify it, do enzyme kinetic analysis, perform docking dynamics simulation analysis between the receptor and the ligands and compare its performance between Cys and Mim synthesis. Cy-OASTL was obtained through both directional degenerate primers corresponding to conserved amino acid region among plant Cys synthase family and the purified protein was 34.3KDa. After cleaving the GST-tag, Cy-OASTL was observed to form mimosine with 3H4P and OAS. The optimum Cys and Mim reaction pH and temperature were 7.5 and $40^{\circ}C$, and 8.0 and $35^{\circ}C$ respectively. Michaelis constant (Km) values of OAS from Cys were higher than the OAS from Mim. Inter fragment interaction energy (IFIE) of substrate OAS-Cy-OASTL complex model showed that Lys, Thr81, Thr77 and Gln150 demonstrated higher attraction force for Cys but 3H4P-mimosine synthase-OAS intermediate complex showed that Gly230, Tyr227, Ala231, Gly228 and Gly232 might provide higher attraction energy for the Mim. It may be concluded that Cy-OASTL demonstrates a dual role in biosynthesis both Cys and Mim and extending the knowledge on the biochemical regulatory mechanism of mimosine and cysteine.

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해밀토니안기법을 이용한 복수어업의 참조기 최적어획량 추정 (Estimating Optimal Harvesting Production of Yellow Croaker Caught by Multiple Fisheries Using Hamiltonian Method)

  • 남종오;심성현;권오민
    • 수산경영론집
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    • 제46권2호
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    • pp.59-74
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    • 2015
  • This study aims to estimate optimal harvesting production, fishing efforts, and stock levels of yellow croaker caught by the offshore Stow Net and the offshore Gill Net fisheries using the current value Hamiltonian method and the surplus production model. As analyzing processes, firstly, this study uses the Gavaris general linear model to estimate standardized fishing efforts of yellow croaker caught by the above multiple fisheries. Secondly, this study applies the Clarke Yoshimoto Pooley(CY&P) model among the various exponential growth models to estimate intrinsic growth rate(r), environmental carrying capacity(K), and catchability coefficient(q) of yellow croaker which inhabits in offshore area of Korea. Thirdly, the study determines optimal harvesting production, fishing efforts, and stock levels of yellow croaker using the current value Hamiltonian method which is including average landing price of yellow croaker, average unit cost of fishing efforts, and social discount rate based on standard of the Korean Development Institute. Finally, this study tries sensitivity analysis to understand changes in optimal harvesting production, fishing efforts, and stock levels of yellow croaker caused by changes in economic and biological parameters. As results drawn by the current value Hamiltonian model, the optimal harvesting production, fishing efforts, and stock levels of yellow croaker caught by the multiple fisheries were estimated as 19,173 ton, 101,644 horse power, and 146,144 ton respectively. In addition, as results of sensitivity analysis, firstly, if the social discount rate and the average landing price of yellow croaker continuously increase, the optimal harvesting production of yellow croaker increases at decreasing rate and then finally slightly decreases due to decreases in stock levels of yellow croaker. Secondly, if the average unit cost of fishing efforts continuously increases, the optimal fishing efforts of the multiple fisheries decreases, but the optimal stock level of yellow croaker increases. The optimal harvest starts climbing and then continuously decreases due to increases in the average unit cost. Thirdly, when the intrinsic growth rate of yellow croaker increases, the optimal harvest, fishing efforts, and stock level all continuously increase. In conclusion, this study suggests that the optimal harvesting production and fishing efforts were much less than actual harvesting production(35,279 ton) and estimated standardized fishing efforts(175,512 horse power) in 2013. This result implies that yellow croaker has been overfished due to excessive fishing efforts. Efficient management and conservative policy on stock of yellow croaker need to be urgently implemented.

생물경제모형을 이용한 참조기의 자원평가에 관한 연구 - 단일어종·다수어업 사례를 중심으로 (A Stock Assessment of Yellow Croaker using Bioeconomic Model: a Case of Single Species and Multiple Fisheries)

  • 심성현;남종오
    • Ocean and Polar Research
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    • 제37권2호
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    • pp.161-177
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    • 2015
  • This study analyzes the stock assessment of yellow croaker caught mainly by the Korean stow net and gill net fisheries focusing on single species and multiple fisheries. This study standardizes fishing efforts for the two fisheries using the general linear model and uses a surplus production model based on the exponential growth model. The Clarke Yoshimoto Pooley model estimates a maximum sustainable yield(MSY), an allowable biological catch(ABC), fishing efforts for MSY($E_{MSY}$) and for ABC($E_{ABC}$). The bio-economic model is used to estimate the maximum economic yield(MEY) and fishing efforts for MEY($E_{MSY}$). Also, the study employs an economic analysis to estimate the economic interaction between stow net and gill net fisheries. The economic analysis shows the profit accruing to the two fisheries from estimated ABC. Finally, the study compares TACs based on single species and single fishery to TAC based on single species and multiple fisheries. The study proposes that the TAC assessment is necessary for single species and multiple fisheries in order to preserve resources.

BCTOC 사례분석을 통한 합리적인 온 독 시스템의 모델 개발 (A Development of Model for Prospective On Dock Terminal System through Analysis of Real Case in BCTOC)

  • 김웅규;도필락;김주영;양원
    • 한국항만학회지
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    • 제13권1호
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    • pp.51-64
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    • 1999
  • This study is on the focus of the cost-effective and time-effective in the BCTOC which commenced the On Dock Termainal System in 1998 for the first time in Korea. On this process of study two categories should be considered : (1) Improvement on Business Process (2) Improvement on Information Technology. With these two accesses a new future-oriented and prospective model could be put on our hand as follows. (1) Improvement on Business Process \circled1Consistency of container In-Out Operation \circled2Simplicity of Rate appraisal \circled3Unified operation on Billing and Request (2) Improvement on Information Technology \circled1Scale up the Information Application \circled2Constructing an one-spot simultaneous Information Holding System \circled3Combination of Internet and Integrated Database System.

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토양용액의 이온조성 추정모델 (Model for Ionic Species Estimation in Soil Solutio)

  • 김유학;윤정희;정병간;김민균
    • 한국토양비료학회지
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    • 제34권3호
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    • pp.213-236
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    • 2001
  • 토양용액의 이온조성은 작물의 양분흡수와 밀접한 관계를 가지고 있으며 양분의 이온조성을 추정하기 위하여 많은 모델이 개발되어 사용되고 있다. 토양용액 중 분석되는 양분의 몰농도는 insoluble 이온쌍과 평형을 이루고 있는 soluble 이온과 이온쌍 그리고 complex등의 농도로 간주하고, 양이온과 음이온을 동시에 고려한 양분의 이온조성을 추정하기 위하여 분석된 양분의 몰농도에 따른 선정된 평형식의 평형상수에 대한 conditional equilibrium constant를 구하여 모든 평형식이 만족되는 이온과 이온쌍의 몰농도를 구하는 모델을 설정하였다. 본 모델 이용시 기본적으로 필요한 성분은 pH, Eh, EC, 양이온 8종(K, Ca, Mg, Na, Fe, Mn, Al, $NH_4{^+}$, 음이온 6종(Si, 5, p Cl, $NO_3{^-}$, $HCO_3{^-}$)이며 다른 성분도 추가할 수 있도록 하였다. 토양과 토양용액이 평형조건인 경우 추정된 이온과 이온쌍의 조성과 이에 따른 존재 가능한 침전량과 mineral 종류별 함량을 계산하였다.

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근막변형모델이 최대악력, 힘 감각 그리고 관절가동범위에 미치는 효과 (The Effect of Fascial Distortion Model on Maximal Grip Strength, Force Sense and Range of Motion)

  • 김지영;김성렬
    • 대한통합의학회지
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    • 제9권1호
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    • pp.33-40
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    • 2021
  • Purpose : The fascia is the body's largest sensory organ affected by mechanical stimuli such as pressure. Fascial distortion model (FDM) is one of the fascia treatment techniques, and it is based that most musculoskeletal problems are caused by three-dimensional distortion of the fascia. Until now, some studies have been conducted to investigate the effect of FDM, but it is still not enough. In this study, among the six techniques of FDM, trigger band (TB) and cylinder distortion (CyD) were applied to the forearm to investigate the immediate effect on the maximal grip strength, force sense and range of motion. Methods : 22 healthy adults in their 20s and 30s participated. Before and after the application of FDM, maximal grip strength, force sense and range of motion were measured. For analysis, a paired t-test was performed, and the significance level was set to p<.05. Results : After FDM, there were a significant differences that increased the force sense and the range of motion (p<.05). But the maximal grip strength did not show a significant difference (p>.05). Conclusion : The results of this study, the FDM did not affect maximal grip strength, but it was shown to increase the sense of force and range of motion. We assumed that it is the result of the changes in the states of the fascia and changes in the activity of mechanical receptors induced by pressure and stretch from FDM application.

Effects of Mungbean Flour Level in Combination with Microbial Transglutaminase on Physicochemical and Textural Properties of Low-salt Pork Model Sausages

  • Lee, Hong Chul;Chin, Koo Bok
    • 한국축산식품학회지
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    • 제33권2호
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    • pp.221-228
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    • 2013
  • This study was performed to evaluate the effects of various levels of mungbean flour (MF) (0-2.4%) on the quality characteristics of pork model sausages (PMS) in experiment 1 and also select the optimum level of MF to enhance the water retention and gelling properties of low-salt PMS (LSPMS) with or without microbial transglutaminase (MTGase) in experiment 2. In experiment 1, the addition of MF did not affect pH, chemical compositions (fat and moisture contents), color values, and functional properties (expressible moisture, EM (%) and cooking yield, CY (%)) of PMS. However, the addition of MF increased the chewiness of PMS and hardness if the mungbean flour at the level of more than 1.2% was incorporated. Since the interaction between the microbial transglutaminase (MTGase) treatment and MF level was not significant (p>0.05), data were pooled by different factors (MTGase treatment and MF level) in experiment 2. MF improved the water binding ability and textural springiness of LSPMS. On the other hand, MTGase treatment decreased the pH and cooking yield (%) of LSPMS, but increased most textural properties. In conclusion, the addition of MF could enhance the water retention and textural properties of PMS and LSPMS, regardless of MTGase, when it was added to over 1.2%. Based on these results, mungbean protein may interact with MTGase on the low-salt comminuted meat systems. Therefore, further study might be needed to understand the mechanisms of interaction between MTGase and functional components induced from MF.

KCCH cyclotron neutron 및 $^{60}Co\;{\gamma}-ray$에 의한 인체 말초혈액 임파구의 염색체 이상측정 (Radiation-Induced Chromosome Aberration in Human Peripheral Blood Lymphocytes In Vitro : RBE Study with Neutrons and $^{60}Co\;{\gamma}-rays$.)

  • 김성호;김태환;정인용;조철구;고경환;류성렬
    • Journal of Radiation Protection and Research
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    • 제17권1호
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    • pp.21-30
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    • 1992
  • KCCH cyclotron neutron(30cCy/min) 및 $^{60}Co\;{\gamma}-ray(210cGy/min)$를 시험관내의 정상인체 말초혈액임파구에 조사하여 염색체이상(dicentric 및 centric ring)을 관찰하고 이의 선량-반응관계식을 linear model$(Y=K_1D+a)$, power-law model$(Y=K_2D^n)$, quadratic model$(Y=K_3D^2)$ 및 linear-quadratic model$(Y={\alpha}D+{\beta}D^2)$을 사용하여 구하고 이들 model중 염색체이상의 측정치와 가장 일치하는 관계식을 근거로 하여 ${\gamma}-ray$에 대한 neutron의 relative biological effectiveness (RBE)를 산출하였다. 염색체 이상(dicentric plus centric ring)의 발생분포는 ${\gamma}-ray$의 경우 linear model(P=0.067)을 제외한 power-law model$[Y=(5.81{\pm}1.96){\times}10^6D^{1.93+0.06},\;P=0.931]$, quadratic model$[Y=(3.91{\pm}0.09){\times}10^{-6}D^2,\;P=0.972]$ 및 linear-quadratic model $[Y=(6.55{\pm}6.83){\times}10^{-5}D+(3.72{\pm}0.22){\times}10^{-6}D^2$ P=0.922]에 적합하였다 neutron의 경우 linear model $(Y=(6.12{\pm}0.17){\times}10^{-3}\;D-0.22,\;P=0.987]$에 가장 일치하였고 quadratic model (P<0.005)을 제외한 power-law model $[Y=(5.36{\pm}3.02) {\times}10^{-4}D^{1.42+0.11},\;P=0.601]$ 및 linear-quadratic model $[Y=(2.43{\pm}0.70){\times}10^{-3}D+(1.21{\pm}0.39){\times}10^{-7}D^2,\;P=0.415]$에 비교적 적합하였다. 세포당 0.1-1.5개의 염색체이상을 나타내는 neutron의 ${\gamma}-ray$에 대한 RBE는 $2.714{\pm}0.408$이었다.

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Average Direct and Maternal Genetic Effects and Heterosis Effects on Body Weight in Two Subspecies of Mice

  • Kurnianto, Edy;Shinjo, Akihisa;Suga, Daisuke
    • Asian-Australasian Journal of Animal Sciences
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    • 제11권5호
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    • pp.475-479
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    • 1998
  • Data on body weights were analyzed in the four genetic groups from all possible crosses of two subspecies of mice to estimate average direct genetic effects (ADGE), average maternal genetic effects (AMGE) and heterotic effect (HE). The genetic groups used were $CF_{{\sharp}1}$ laboratory mouse (Mus musculus domesticus), Yonakuni wild mouse (Yk, Mus musculus molossinus yonakuni) and two reciprocal $F_1$ crosses of them, CY and YC. First symbol in the reciprocal $F_1$ represent subspecies of dam. Body weight at 1 (Wk1), 3 (Wk3), 6 (Wk6) and 10 weeks of age (Wk10) were analyzed from 258 mice of the four genetic groups. The model used to evaluate body weights included main effects of genetic group and sex, and interaction effect between genetic group and sex. The ADGE and the AMGE were estimated as deviations of Yk from $CF_{{\sharp}1}$. The HE was estimated from the differences between the reciprocal $F_1$ and the midparent mean. Results of this study showed that all effects, except sex and interaction between genetic group and sex at Wk1 and Wk3, were highly significant source variation (p < 0.01). The ADGE were positive and highly significant (p < 0.01) at all ages studied for both sexes, while the AMGE were highly significant at Wk3, Wk6 and Wk10. The ADGE were larger in contributing effect on body weight differences than the AMGE. The positive value of the HE were observed at all ages for males, while for females the positive effects occured from birth through weaning.