• Title/Summary/Keyword: CV5(Serk-Moon)

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Effects of Moxibustion at the CV5(Serk-Moon) on the Expression of $3{\beta}-Hydroxysteroid\; dehydrogenasa/{\Delta}5-{\Delta}4$ isomerase $(3{\beta}-HSD)$ in Ovary of the Rats (석문(石門)($CV_5$) 애구(艾灸)가 자성(雌性) 백서(白鼠)의 $3{\beta}-hydroxysteroid\;dehydrogenasa/{\Delta}^5-{\Delta}^4$ isomerase $(3{\beta}-HSD)$의 발현(發顯) 양상(樣相)에 미치는 영향(影響))

  • Choi, Young-Sun;Ahn, Sung-Hun;Koo, Sung-Tae;Lee, Mun-Ho;Kim, Kyung-Sik;Sohn, In-Chul
    • The Journal of Korean Medicine
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    • v.20 no.2
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    • pp.63-74
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    • 1999

  • We demonstrated the moxibution on CV5(Serk-Moon) and CV3(Chung-Guk), as we have known contraceptive acupuncture point and pregnancy acupuncture point in oriental medcine, effected on concentration of progesteron and estrogen. As the reports, $3{\beta}-hydroxysteroid\;dehydrogenase/{\Delta}5-{\Delta}4$ isomerase $(3{\beta}-HSD)$ is an enzyme that has catalytic oxidation and isomerase reaction on steroidhormon synthase including progesteron and estrogen. So we observated the concentration and mass of $(3{\beta}-HSD)$ by immuno-chemicalstain, western blot and Enzyme-Linked Immunosorbent Assay in rat ovary. In results, we detected that the mass of $(3{\beta}-HSD)$ decreased significantly in moxibution treated group on CV5($p{\leq}0.05$) in rat ovary and proposed that the moxibution of CV5 make possible to contraception because of blocking estrogen synthesis by $(3{\beta}-HSD)$ decrease. But we didn't know moxibution effects exactly whether is biochemical reaction or thermal reaction on acupuncture point.

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