• Korean Journal of Acupuncture
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• v.26 no.4
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• pp.1-11
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• 2009

Objectives : The object of this study is measuring energy (skin capacitance) distribution on the specific acupionts and analyzing change patterns of meridian energy according to time or synchronous time. Methods : To check energy distribution using the meridian energy measurement system(DMM-1000), ten specific acupoints(ST34, ST36, ST40, ST41, ST42, ST43, ST44, ST45, BL21, CV12) were chosen. We checked the energy distribution and analyzed the change patterns before and after meal. We checked the state of the energy of ST meridian which is considered to have relation to stomach organ activity. Based on the hypothesis regarding energy difference due to Qi flowing, we compared energy potential on 10 specific acupoints. Results and Conclusions : Electric energy of each specific acupoint was different according to subjects and time. Through this study, we proposed an indispensable condition of energy difference due to Qi flowing through meridian.

• Annals of Laboratory Medicine
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• v.38 no.6
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• pp.530-537
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• 2018

Background: Measurement of insulin and C-peptide concentrations is important for deciding whether insulin treatment is required in diabetic patients. We aimed to investigate the analytical performance of insulin and C-peptide assays using the Lumipulse G1200 system (Fujirebio Inc., Tokyo, Japan). Methods: We examined the precision, linearity, and cross-reactivity of insulin and C-peptide using five insulin analogues and purified proinsulin. A method comparison was conducted between the Lumipulse G1200 and Roche E170 (Roche Diagnostics, Mannheim, Germany) systems in 200 diabetic patients on insulin treatment. Reference intervals for insulin and C-peptide concentrations were determined in 279 healthy individuals. Results: For insulin and C-peptide assays, within-laboratory precision (% CV) was 3.78-4.14 and 2.89-3.35%, respectively. The linearity of the insulin assay in the range of 0-2,778 pmol/L was $R^2=0.9997$, and that of the C-peptide assay in the range of 0-10 nmol/L was $R^2=0.9996$. The correlation coefficient (r) between the Roche E170 and Lumipulse G1200 results was 0.943 (P <0.001) for insulin and 0.996 (P <0.001) for C-peptide. The mean differences in insulin and C-peptide between Lumipulse G1200 and the Roche E170 were 19.4 pmol/L and 0.2 nmol/L, respectively. None of the insulin analogues or proinsulin showed significant cross-reactivity with the Lumipulse G1200. Reference intervals of insulin and C-peptide were 7.64-70.14 pmol/L and 0.17-0.85 nmol/L, respectively. Conclusions: Insulin and C-peptide tests on the Lumipulse G1200 show adequate analytical performance and are expected to be acceptable for use in clinical areas.

• The Korean journal of internal medicine
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• v.33 no.6
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• pp.1119-1128
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• 2018

Background/Aims: In multicenter clinical trials, laboratory tests are performed in the laboratory of each center, mostly using different measuring methodologies. The purpose of this study was to evaluate coefficients of variation (CVs) of laboratory results produced by various measuring methods and to determine whether mathematical data adjustment could achieve harmonization between the methods. Methods: We chose 10 clinical laboratories, including Green Cross Laboratories (GC Labs), the central laboratory, for the measurement of total cholesterol, high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), serum triglycerides, creatinine, and glucose. The serum panels made with patient samples referred to GC Labs were sent to the other laboratories. Twenty serum samples for each analyte were prepared, sent frozen, and analyzed by each participating laboratory. Results: All methods used by participating laboratories for the six analytes had traceability by reference materials and methods. When the results from the nine laboratories were compared with those from GC Labs, the mean CVs for total cholesterol, HDL-C, LDL-C, and glucose analyzed using the same method were 1.7%, 3.7%, 4.3%, and 1.7%, respectively; and those for triglycerides and creatinine analyzed using two different methods were 4.5% and 4.48%, respectively. After adjusting data using Deming regression, the mean CV were 0.7%, 1.4%, 1.8%, 1.4%, 1.6%, and 0.8% for total cholesterol, HDL-C, LDL-C, triglyceride, creatinine, and glucose, respectively. Conclusions: We found that more comparable results can be produced by laboratory data harmonization using commutable samples. Therefore, harmonization efforts should be undertaken in multicenter trials for accurate data analysis (CRIS number; KCT0001235).

• The Transactions of The Korean Institute of Electrical Engineers
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• v.67 no.12
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• pp.1641-1647
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• 2018

In this paper, we describe a portable potentiostat which is capable of cyclic voltammetry(CV) and amperometry for electrochemical dissolved oxygen sensor. In addition, this portable potentiostat can also transmit the measured data wirelessly to android devices such as smart phone, tablet, etc. through Bluetooth. The potentiostat system consists of three parts; a voltage generator circuit which is controlled by Arduino nano and 12-bit DAC(digital to analog converter) to generate necessary electric potential for operating the electrochemical sensor, an oxidation/reduction current measurement circuit, and a Bluetooth module to transmit data wirelessly to an android device. Once measurements are carried out with the android application, the measured data is transmitted to the android device via Bluetooth and displayed using the android app. in real time. In this paper, we report the measured reduction current with a fabricated dissolved oxygen sensor in both saturated-oxygen state and zero-oxygen states. The results of the developed portable potentiostat system are in good agreement with those of the commercial portable potentiostat (${\mu}stat200$, Dropsens inc.). The measured peak reduction currents using the developed potentiostat and the commercial ${\mu}stat200$ potentiostat were $-0.755{\mu}A$ and $-0.724{\mu}A$, respectively. The reduction currents measured at zero-oxygen state were $-0.005{\mu}A$ and $-0.004{\mu}A$. The discrepancy between those two systems seems very small, which implies successful development of a portable and wireless potentionstat.

• Journal of the Korea Convergence Society
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• v.12 no.5
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• pp.17-22
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• 2021

Eco-friendly magnesium-air battery is a kind of metal-air battery known as a primary battery with a very high theoretical discharge capacity. This battery is also called a metal-fuel cell from the viewpoint of using oxygen in the atmosphere as a cathode active material and magnesium alloy as a fuel. Since battery performance is determined by the properties of the magnesium alloy used as a anode, more research and development of the magnesium alloy electrode as a anode material are required in order to commercialize it as a high-performance battery. In this study, the commercialized magnesium alloys(AZ31, AZ61) were selected and then electrochemical measurements and discharge test were conducted. Electrochemical properties of magnesium alloys were investigated by OCP changes, Tafel parameters and CV measurement, and the feasibilities of AZ61 alloy with excellent discharge capacity(1410mAhg^-1) as electrode materials were evaluated through CC discharge experiments.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.279-279
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• 2022

최근 이미지분석 기술은 하드웨어 및 소프트웨어 기술의 급격한 발전으로 인해 의학, 생물학, 지리학, 재료공학 등에서 수많은 연구 분야에서 광범위하게 활용되고 있으며, 이미지분석은 다량의 토사에 대하여 입경을 포함한 형상학적 특성을 간편하게 정량화 할 수 있기 때문에 매우 효과적인 분석 방법으로 판단된다. 현재 모래의 입도분석 방법으로는 신뢰성 있는 체가름 시험법(KSF2302) 등이 있으나, 번거로운 처리과정과 많은 시간이 소요된다. 또한 입자형상은 입경이 세립 할수록 직접 측정이 어렵기 때문에, 최근에는 이미지 분석을 이용하는 방법이 시도되고 있다. 본 연구에서는 75㎛ 이상의 조립질 하상 토사 이미지를 취득하여, 입자들의 장·축단 길이, 면적, 둘레, 공칭직경 및 종횡비 등의 형상학적 특성인자를 자동으로 측정하는 프로그램 개발을 수행하였다. 프로그램은 이미지 분석에 특화된 라이브러리인 OpenCV(Open Source Computer Vision)를 적용하였다. 이미지 분석 절차는 크게 이미지 취득, 기하보정, 노이즈제거, 객체추출 및 형상인자 측정 단계로 구성되며, 이미지 취득시 패널의 하단에 Back light를 부착해 시료에 의해 발생되는 음영을 제거하였다. 기하보정은 원근변환(perspective transform)을 적용했으며, 노이즈 제거는 모폴로지 연산과 입자간의 중첩으로 인한 뭉침을 제거하기 위해 watershed 알고리즘을 적용하였다. 최종적으로 객체의 외곽선 추출하여 입자들의 다양한 정보(장축, 단축, 둘레, 면적, 공칭직경, 종횡비)를 산출하고, 분포형으로 제시하였다. 본 연구에서 제안하는 이미지분석을 적용한 토사의 형상학적 특성 측정 방법은 시간과 비용의 측면에서 보다 효율적으로 하상 토사에 대한 다양한 정보를 획득 할 수 있을 것으로 기대한다.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.33 no.1
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• pp.55-59
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• 2000

A specific and sensitive sandwich enzyme-immunoassay (EIA) using Avidin-Biotin complex was developed for the measurement of GTH II levels in pituitary content and pituitary cell culture medium of the rainbow trout-(Oncorhpchus mykiss). Biotin-salmon GTH II rabbit IgG (sefondary antibody) wai purified by a protein A sepharose affinity chromatography column and that was biotinylated by using Biotin-N-hydroxysuccinimide ofter (BNHS). Non-biotin salmon GTH II rabbit IgG (first antibody) was obtained only through a protein A sepharose affinity chromatography column. The assay was performed by the so-called 'sandwich' method using a microtiter plate, A dose-response curve was obtained between $0.12 to 125 ng/ml$ of salmon GTH II. The displacement curves for pituitary extraction and pituitary cell culture medium of testosterone-treated rainbow trout were Parallel to the standard curie. The intra-assay and inter-assay coefficients of variation (CV) were $8.2{\%} (N=5) and 12.5{\%} (N=6)$, respectively, This assay system was used to measure the amount of GTH II that accumulated in the culture medium of dispersed pituitary cells in testosterone-treated immature rainbow trout, The accumulation was increased with the amount or salmon gonadotropin-releasing hormone. GTH II values determined by the present method were well correlated with those determined by radioimmunoassay. As a result, this assay system was found to be suitable for the measurement of GTH II for pituitary extraction and pituitary culture medium in many salmonid fishes.

• Journal of Bio-Environment Control
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• v.18 no.3
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• pp.258-265
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• 2009

This research was conducted to compare drymatter production and yield pattern between commercial glasshouse (G) and plastic greenhouse (PG) in Korea. In both greenhouses sawing and plating of sweet pepper was 28 August and 27 September, 2007. Destructive measurement and yield of sweet pepper, cv. 'Derby', was obtained from January to May, 2008. Averaged light transmissivity over 20 times observed 65% in G and 51 % in PG. The averaged daily radiation sum of greenhouses during whole growing period was $9.03MJ/m^2/day$ for G and $7.37MJ/m^2/day$ for PG Leaf area index (LAI) in G crop was 36% higher than the crop in PG at the end of experiment (247days after planting: DAP), whereas there was no significantly difference for 212 DAP in both greenhouses. Total dry matter production was $1759.9g{\cdot}m^{-2}$ for G and $1308.5g{\cdot}m^{-2}$ for PG Fruit production observed $14.1kg{\cdot}m^{-2}$ in G and $7.8kg{\cdot}m^{-2}$ in PG. There was slightly difference measurement of dry matter distribution of generative or vegetative parts to total dry matter between G and PG.

• Proceedings of the Korean Society of Crop Science Conference
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• 2005.08a
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• pp.57-74
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• 2005

Rice yield and protein content have been shown to be highly variable across paddy fields. In order to characterize this spatial variability of rice within a field, the two-year experiments were conducted in 2002 and 2003 in a large-scale rice field of $6,600m^2$ In year 2004, an experiment was conducted to know if prescribed N for site-specific fertilizer management at panicle initiation stage (VRT) could reduce spatial variation in yield and protein content of rice while increasing yield compared to conventional uniform N topdressing (UN, ,33 kg N/ha at PIS) method. The trial field was subdivided into two parts and each part was subjected to UN and VRT treatment. Each part was schematically divided in $10\times10m$ grids for growth and yield measurement or VRT treatment. VRT nitrogen prescription for each grid was calculated based on the nitrogen (N) uptake (from panicle initiation to harvest) required for target rice protein content of $6.8\%$, natural soil N supply, and recovery of top-dressed N fertilizer. The required N uptake for target rice protein content was calculated from the equations to predict rice yield and protein content from plant growth parameters at panicle initiation stage (PIS) and N uptake from PIS to harvest. This model equations were developed from the data obtained from the previous two-year experiments. The plant growth parameters for this calculation were predicted non-destructively by canopy reflectance measurement. Soil N supply for each grid was obtained from the experiment of year 2003, and N recovery was assumed to be $60\%$ according to the previous reports. The prescribed VRT N ranged from 0 to 110kg N/ha with average of 57kg/ha that was higher than 33kg/ha of UN. The results showed that VRT application successfully worked not only to reduce spatial variability of rice yield and protein content but also to increase rough rice yield by 960kg/ha. The coefficient of variation (CV) for rice yield and protein content was reduced significantly to $8.1\%\;and\;7.1\%$ in VRT from $14.6\%\;and\;13.0\%$ in UN, respectively. And also the average protein content of milled rice in VRT showed very similar value of target protein content of $6.8\%$. Although N use efficiency of VRT compared to UN was not quantified due to lack of no N control treatment, the procedure used in this paper for VRT estimation was believed to be reliable and promising method for managing within-field spatial variability of yield and protein content. The method should be received further study before it could be practically used for site-specific crop management in large-scale rice field.

• Journal of the Korean Society of Radiology
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• v.6 no.6
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• pp.447-454
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• 2012

To examine the performance of a diagnostic X-ray system, we tested a linearity, reproducibility, and Half Value Layer(HVL). The linearity was examined 4 times of irradiation with a given condition, and we recorded a level of radiation. We then calculated the mR/mAs. And the measured value should not be more than 0.1. If the measured value was more than 0.1, we could know that the linearity was decreased. The reproducibility was analyzed 10 times of irradiations at 80kVp, 200mA, 20mAs and 120kVp, 300mA, 8mAs. The values from these analyses were integrated into CV equation, and we could get outputs. The reproducibility was good if the output was lower than 0.05. HVL was measured 3 times of irradiation without a filter, and we inserted additional HLV filters with 0, 1, 2, 4 mm of thickness. We tested the values until we get the measured value less than a half of the value measured without additional filter. We tested the linearity, the reproducibility, and HVL of 5 diagnostic X-ray generators in this facilities. The linearity of No. 1 and No. 5 generator didn't satisfy the standard for radiation safety around 300mA~400mA and 100mA~200mA, respectively. HVL of No.1 generator was not satisfied at 80kVp. The outputs were higher in the three-phase equipment than the single-phase equipment. The old generators need to maintain and exchange of components based on the these results. Then, we could contribute to getting more exact diagnosis increasing a quality of the image and decreasing an expose dose of radiation.