• Title/Summary/Keyword: CTSF

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A Procedure for Computing Conduction Time Series Factors for Walls and Roofs with Large Thermal Capacity by Finite Difference Method (열용량이 큰 벽체나 지붕재의 전도시계열 계수를 유한차분법으로 구하는 과정)

  • Byun, Ki-Hong
    • Journal of the Korean Solar Energy Society
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    • v.38 no.5
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    • pp.27-36
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    • 2018
  • The purpose of this paper is to apply the numerical solution procedure to compute conduction time series factors (CTSF) for construction materials with large thermal capacities. After modifying the procedure in Ref. [9], it is applied to find the CTSF for the wall type 19 and the roof type 18 of ASHRAE. The response periods for one hr pulse load are longer than 24hrs for these wall and roof. The CTSF generated using modified procedure agree well with the values presented in the ASHRAE handbook. The modified procedure is a general procedure that can be applied to find CTSF for materials with complex structures. For the large thermal capacity materials, it should be checked whether thermal response period of the material is over 24hr or not. With suggested solution procedure, it is easy to check the validity of the CTSF based on 24hr period.

Alu-Derived Alternative Splicing Events Specific to Macaca Lineages in CTSF Gene

  • Lee, Ja-Rang;Park, Sang-Je;Kim, Young-Hyun;Choe, Se-Hee;Cho, Hyeon-Mu;Lee, Sang-Rae;Kim, Sun-Uk;Kim, Ji-Su;Sim, Bo-Woong;Song, Bong-Seok;Jeong, Kang-Jin;Lee, Youngjeon;Jin, Yeung Bae;Kang, Philyong;Huh, Jae-Won;Chan, Kyu-Tae
    • Molecules and Cells
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    • v.40 no.2
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    • pp.100-108
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    • 2017
  • Cathepsin F, which is encoded by CTSF, is a cysteine proteinase ubiquitously expressed in several tissues. In a previous study, novel transcripts of the CTSF gene were identified in the crab-eating monkey deriving from the integration of an Alu element-AluYRa1. The occurrence of AluYRa1-derived alternative transcripts and the mechanism of exonization events in the CTSF gene of human, rhesus monkey, and crabeating monkey were investigated using PCR and reverse transcription PCR on the genomic DNA and cDNA isolated from several tissues. Results demonstrated that AluYRa1 was only integrated into the genome of Macaca species and this lineage-specific integration led to exonization events by producing a conserved 3' splice site. Six transcript variants (V1-V6) were generated by alternative splicing (AS) events, including intron retention and alternative 5' splice sites in the 5' and 3' flanking regions of CTSF_AluYRa1. Among them, V3-V5 transcripts were ubiquitously expressed in all tissues of rhesus monkey and crab-eating monkey, whereas AluYRa1-exonized V1 was dominantly expressed in the testis of the crab-eating monkey, and V2 was only expressed in the testis of the two monkeys. These five transcript variants also had different amino acid sequences in the C-terminal region of CTSF, as compared to reference sequences. Thus, species-specific Alu-derived exonization by lineage-specific integration of Alu elements and AS events seems to have played an important role during primate evolution by producing transcript variants and gene diversification.

A Procedure for Computing Conduction Time Series Factors by Numerical Method (전도 시계열 계수를 수치해석으로 구하는 방법)

  • Byun, Ki-Hong
    • Journal of the Korean Solar Energy Society
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    • v.37 no.5
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    • pp.77-84
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    • 2017
  • The purpose of this paper is to propose the way of computing conduction time series factors (CTSF) using numerical method. After the accuracy of the numerical solution procedure being verified, the method is applied to the wall type 24 and roof type 14 of ASHARE to find the conduction time series coefficients, so called conduction time series factors. The results agree well with the values presented in the ASHRAE handbook. The method proposed can be easily applied to find unknown CTSF for more complex structures. It provides information about the temperature changes at a given location and time, thus validity of generated CTSF can be checked easily.