• Title/Summary/Keyword: CS

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연재 - 인디자인 CS4의 화면 구성과 신기능

  • Park, Song-Won
    • 프린팅코리아
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    • v.8 no.12
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    • pp.110-113
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    • 2009
  • Adobe? InDesign?의 최신 버전은 CS4이다. Adobe의 CS4 버전은 전반적으로 작업 시간 단축이라는 공통된 특징을 가지고 있다. 특히 InDesign CS4는 온라인 출판과 오프라인 출판의 경계가 허물어질 수 있을 정도로 다른 프로그램과의 호환성이 강력해졌다. 이번 호에서는 인디자인 CS4의 전반적인 화면의 모습과 신기능 및 향상된 기능에 대해 알아본다.

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Direct Block of Cloned $K^+$ Channels, Kv1.5 and Kv1.3, by Cyclosporin A, Independent of Calcineurin Inhibition

  • Choi, Bok-Hee;Hahn, Sang-June
    • The Korean Journal of Physiology and Pharmacology
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    • v.9 no.6
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    • pp.353-361
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    • 2005
  • The interaction of cyclosporine A (CsA), an immunosuppressant, with rat brain Kv1.5 (Kv1.5) channels, which were stably expressed in Chinese hamster ovary cells, was investigated using the whole-cell patch-clamp technique. CsA reversibly blocked Kv1.5 currents at +50 mV in a reversible concentrationdependent manner with an apparent $IC_{50}$ of 1.0μM. Other calcineurin inhibitors (cypermethrin, autoinhibitory peptide) had no effect on Kv1.5 and did not prevent the inhibitory effect of CsA. Fast application of CsA led to a rapid and reversible block of Kv1.5, and the onset time constants of the CsA-induced block were decreased in a concentration-dependent manner. The CsA-induced block of Kv1.5 channels was voltage-dependent, with a steep increase over the voltage range of channel opening. However, the block exhibited voltage independence over the voltage range in which channels were fully activated. The rate constants for association and dissociation of CsA were $7.0{\mu}M{-1}s^{-1}$ and $8.1s^{-1}$, respectively. CsA slowed the deactivation time course, resulting in a tail crossover phenomenon. Block of Kv1.5 by CsA was use-dependent. CsA also blocked Kv1.3 currents at +50 mV in a reversible concentration-dependent manner with an apparent $IC_{50}$ of $1.1{\mu}M$. The same effects of CsA on Kv1.3 were also observed in excised inside-out patches when applied to the internal surface of the membrane. The present results suggest that CsA acts directly on Kv1.5 currents as an open-channel blocker, independently of the effects of CsA on calcineurin activity.

Adsorption Characteristics of Radioactive Cs Ion by Zeolite X (제올라이트 NaX에 의한 방사성 물질인 Cs 이온의 흡착 특성)

  • Lee, Chang-Han;Lee, Min-Gyu
    • Journal of Korean Society of Environmental Engineers
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    • v.39 no.2
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    • pp.66-73
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    • 2017
  • This study was to evaluate the influential parameters such as intial Cs concentration, reaction temperature, contact time and pH variation of solution on Cs adsorption. Using the experimental data, adsorption kinetics, isotherms and thermodynamic properties were analyzed. The Cs ion adsorption of the zeolite X was effective in the range from pH 5 to 10 and reached equilibrium after 60 minutes. The adsorption kinetics and isotherms of Cs ion with the zeolite X was described well by the pseudo-second-order kinetic and Langmuir isotherm model. The maximum adsorption capacities of Cs ion calculated from Langmuir isotherm model at 293~333 K were from 303.03 mg/g to 333.33 mg/g. It was found that thermodynamic property of Cs ion absorption on the zeolite X was spontaneous and endothermic reaction. The experimental data were fitted a second-order polynomial equation by the multiple regression analysis. The values of the dependent variable calculated by this best fitted model equation were in very good agreement with the experimentally obtained values.

$Cs^+$이온 반응성 산란에 의한 Si(111)-7$\times$7 표면에서의 산소 흡착 연구

  • Kim, Gi-Yeo;Kang, Heon
    • Proceedings of the Korean Vacuum Society Conference
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    • 2000.02a
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    • pp.153-153
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    • 2000
  • Si 산화는 반도체 공정상 필요한 과정으로 산업적으로나 학문적으로 중요하고 많이 연구되었다. 이중에서 Si(1110-7x7표면에서 초기 흡착된 산소는 준안정적 상태로 존재하며 표면온도, 산소의 노출량 그리고 진공도에 따라 그 수명이 제한된다. 이러한 준안정적 상태의 산소의 화학적 성질은 여러 표면분석장비가 동원되어 연구되었으나 아직까지 논쟁이 되고 있다. 이 경우 산소가 어떤 상태로 존재하는가는 표면화학종을 검출함으로서 해결될 수 있다. 저에너지 Cs+ 이온 반응성 산란은 이러한 요구를 충족시킬수 있는 가장 적합한 실험 방법중의 하나이다. 저에너지 Cs+ 이온 산란의 특징 중의 하나는 입사된 Cs+ 이온이 표면에 흡착된 화학종과 충돌후 탈착되면서 반응을 하여 송이 이온을 형성한다는 것이다. 이 송이 이온을 관측함으로서 표면에 존재하는 화학종을 알아 낼 수 있다. 이에 산소가 흡착된 Si(111)-7x7 표면에서의 산소의 준안정적 상태가 저에너지 Cs+ 이온 산란 실험을 통하여 연구되었다. 실험은 0.2-2L(1Langmuir = 10-6 Torr x 1 sec) 산소 노출량과 -15$0^{\circ}C$ - $25^{\circ}C$의 표면온도 그리고 5eV - 20eV의 Cs+ 이온 충돌에너지에서 CsSiO+ 이온이 유일한 생산물로서 검출되었다. CsSiO+ 이온은 입사된 Cs+ 이온과 표면에 존재하는 SiO 분자가 충돌 후 반응하여 탈착된 것으로 생각된다. 이것은 낮은 산소 노출량 즉, 초기 산화 단계에서 SiO가 표면에 존재한다는 것을 의미한다. 즉, 산소 분자는 산화단계의 초기에 해리되어 표면에 흡착되고 선구물질인 SiO를 형성함을 제시한다. 최근의 이론적 계산인 density functional calculation에서도 산소분자가 Si(111)-7$\times$7 표면의 준안정적 산화상태의 선구물질일 가능성을 배제한다. 이는 본 저에너지 Cs+ 이온 반응성 산란실험을 뒷받침하는 계산 결과이다. 높은 Cs+ 이온 충돌에너지에서 CsSi+, Si+, SiO+, Si2+, Si2O+ 등이 추가로 검출되었다. 이는 CsSi 이온을 제외하고 수 keV의 충돌에너지를 사용하는 이차 이온 질량 분석법과 비슷한 결과이다.

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Synthesis of Nano Sulfur/Chitosan-Copper Complex and Its Nematicidal Effect against Meloidogyne incognita In Vitro and on Coffee Pots

  • Hong Nhung Nguyen;Phuoc Tho Tran;Nghiem Anh Tuan Le;Quoc Hien Nguyen;Duy Du Bui
    • The Plant Pathology Journal
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    • v.40 no.3
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    • pp.261-271
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    • 2024
  • Sulfur is one of the inorganic elements used by plants to develop and produce phytoalexin to resist certain diseases. This study reported a method for preparing a material for plant disease resistance. Sulfur nanoparticles (SNPs) stabilized in the chitosan-Cu2+ (CS-Cu2+) complex were synthesized by hydrolysis of Na2S2O3 in an acidic medium. The obtained SNPs/CS-Cu2+ complex consisting of 0.32% S, 4% CS, and 0.7% Cu (w/v), contained SNPs with an average size of ~28 nm as measured by transmission electron microscopy images. The X-ray diffraction pattern of the SNPs/CS-Cu2+ complex showed that SNPs had orthorhombic crystal structures. Interaction between SNPs and the CS-Cu2+ complex was also investigated by ultraviolet-visible. Results in vitro nematicidal effect of materials against Meloidogyne incognita showed that SNPs/CS-Cu2+ complex was more effective in killing second-stage juveniles (J2) nematodes and inhibiting egg hatching than that of CS and CS-Cu2+ complex. The values of LC50 in killing J2 nematodes and EC50 in inhibiting egg hatching of SNPs/CS-Cu2+ complex were 75 and 51 mg/l, respectively. These values were lower than those of CS and the CS-Cu2+ complex. The test results on the nematicidal effect against M. incognita on coffee pots showed that the SNPs/CS-Cu2+ complex was 100% effective at a concentration of 150 mg/l. Therefore, the SNPs/CS-Cu2+ complex could be considered as a biochemical material with potential for agricultural applications to control root-knot nematodes.

In vivo Antibacterial Activity of DA-1131, A New Carbapenem Antibiotic

  • Kim, Ji-Young;Kim, Gye-Won;Park, Seong-Hak;Im, Weon-Bin;Chang, Min-Sun;Junnick Yang
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1996.04a
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    • pp.240-240
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    • 1996
  • Staphylococcus aureus, Klebsiella pneumoniae, Enterobacter cloacae, Proteus mirabilis 및 Pseudomonas aeruginosa에 의한 mouse 복강내감염증에 대하여 DA-1131은 IPM/CS와 MEPM/CS에 비하여 현저히 우수한 치료효과를 나타내었다. 백혈구감소 mouse에서의 P. aeruginosa에 의한 복강내감염증에 대하여도 DA-1131은 IPM/CS와 MEPM 및 MEPM/CS보다 동등 이상의 우수한 치료효과를 나타내었다. K. pneumoniae를 감염균으로 한 mouse 호흡기감염 후 생존율 평가 시험에서 DA-1131 투여 mouse는 IPM/CS 및 MEPM/CS에 비하여 현저히 우수한 생존율을 나타내었고, 동시에 MEPM/CS와 유사한 폐내 생균수의 감소 pattern이 확인되었으며, IPM/CS에 비하여 균의 재증식을 억제하는 효과가 우수하였다. P. mirabilis에 의한 mouse 요로감염증에서는 DA-1131 투여군의 신장내 생균수감소는 MEPM/CS와 동등한 수준인 것으로 나타났으나 IPM/CS에 비하여는 매우 우수하였다.

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133Cs Nuclear Magnetic Resonance Relaxation Study of the Phase Transition of Cs2MnCl4·2H2O Single Crystals

  • Heo, Cheol;Lim, Ae-Ran
    • Journal of the Korean Magnetic Resonance Society
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    • v.14 no.2
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    • pp.76-87
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    • 2010
  • The structural phase transition of $Cs_2MnCl_4{\cdot}2H_2O$ single crystals was investigated by determining the $^{133}Cs$ spin-lattice relaxation time $T_1$. The number of resonance lines in the $^{133}Cs$ spectrum changes from seven to one near 375 K, which means that above 375 K the Cs sites are symmetric. Further, the $T_1$ of the $^{133}Cs$ nucleus undergoes a significant change near 375 K, which coincides with the change in the splitting of the $^{133}Cs$ resonance lines. The change in $T_1$ near $T_C$ is related to the loss of $H_2O$, and means that the forms of the octahedra of water molecules surrounding $Cs^+$ are disrupted.

Radioactivity data analysis of 137Cs in marine sediments near severely damaged Chernobyl and Fukushima nuclear power plants

  • Song, Ji Hyoun;Kim, TaeJun;Yeon, Jei-Won
    • Nuclear Engineering and Technology
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    • v.52 no.2
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    • pp.366-372
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    • 2020
  • Using several accessible published data sets, we analyzed the temporal change of 137Cs radioactivity (per unit mass of sample) in marine sediments and investigated the effect of the water content of sediment on the 137Cs radioactivity, to understand the behavior of 137Cs present in marine environments. The 137Cs radioactivity in sediments decreased more slowly in the Baltic Sea (near the Chernobyl nuclear power plant) than in the ocean near the Fukushima Daiichi nuclear power plant (FDNPP). The 137Cs radioactivity in the sediment near the FDNPP tended to increase as the water content increased, and the water content decreased at certain sampling sites near the FDNPP for several years. Additionally, the decrease in the water content contributed to 51.2% of the average 137Cs radioactivity decrease rate for the same period. Thus, it may be necessary to monitor both the 137Cs radioactivity and the water content for marine sediments to track the 137Cs that was discharged from the sites of Chernobyl and Fukushima nuclear power plants where severe accidents occurred.

Properties of Sol-gel Coating Materials Synthesized from Colloidal Silicas and Methyltrimethoxysilane (Colloidal Silica와 Methyltrimethoxysilane간의 졸겔반응으로 합성된 코팅제 특성 연구)

  • 강동필;박효열;안명상;이태희;명인혜;강귀태
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.17 no.9
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    • pp.967-972
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    • 2004
  • Hardness and surface property of coated gel materials are considerably different according to kinds(particle size/stabilized ion) of colloidal silica(CS), kinds of silanes, content ratio of silane versus CS, and reaction degree in sol solution. We report the properties of sol-gel coating materials in which the factors of reaction are kinds of CS, contents ratio of CS and MTMS, and reaction time of sol. The contact angles of the coated films obtained from the mixed CS system showed a little good relationship with MTMS content increase to those from HSA CS reaction system and the change of contact angle didn't have much effect on reaction time of sol. In the coating films obtained from HSA CS reaction system, the surface was much rough in case of that the content MTMS decreased and the reaction of sol kept long. The surface roughness of films obtained from the mixed CS reaction system showed similar tendency, though its degree was a little different. In synthesis of sol-gel coating materials, we could identify that choice of CS kinds and content ratio of CS and silane were important and it was desirable the reaction time of sol is not long.

Studies on the Sorption Characteristics of $^{137}Cs$ onto Granite and Tuff ($^{137}Cs$의 화강암 및 응회암에 대한 흡착특성에 관한 연구)

  • Cho, Young-Hwan;Hahn, Pil-Soo;Park, Sang-Won
    • Nuclear Engineering and Technology
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    • v.27 no.1
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    • pp.25-32
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    • 1995
  • Batch sorption experiments were conducted to investigate the sorption characteristics of $^{137}$ Cs, known for the primary target of safety assessment in low-level radwaste disposal, onto domestic rocks such as Granite and Tuff. A response surface analysis method was applied to quantify the effect of 3 independent variables ([Cs], [Vol/Wt], [pH]) on the sorption. Ac a result, initial Cs concentration appeared to be the most important variable within the range of the study. A significant effect of [Vol/Wt] on Kd was observed. The sorption of Cs was pH-insignificant. The sorption extent of nuclides onto tuff was more significant than that onto granite. The pH-insignificant sorption behavior of Cs was discussed in terms of the surface electrical properties and the solution chemistry. The sorption tendency of nuclides onto geomedia studied was interpreted by adopting the water structure modification theory.

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