• BMB Reports
• /
• v.43 no.1
• /
• pp.29-33
• /
• 2010

It is well known that PR/SET family members participate in transcriptional regulation via chromatin remodeling. PRDM10 might play an essential role in gene expression, but no such evidence has been observed so far. To assess PRDM10 expression at various stages of mouse development, we performed immunohistochemistry using available PRDM10 antibody. Embryos were obtained from three distinct developmental stages. At E8.5, PRDM10 expression was concentrated in the mesodermal and neural crest populations. As embryogenesis proceeded further to E13.5, PRMD10 expression was mainly in mesoderm-derived tissues such as somites and neural crest-derived populations such as the facial skeleton. This expression pattern was consistently maintained to the fetal growth period E16.5 and adult mouse, suggesting that PRDM10 may function in tissue differentiation. Our study revealed that PRDM10 might be a transcriptional regulator for normal tissue differentiation during mouse embryonic development.

• Proceedings of the Korean Society of Agricultural Engineers Conference
• /
• 2005.10a
• /
• pp.349-354
• /
• 2005

In this study, settlement characteristics of 23 CFRD was investigated from monitoring data and the method to estimate the crest settlements considering internal settlement during constructions was proposed. Moreover, crest settlement smaller than 20cm and deflection of face slab smaller than 20cm are not considered to be critical to the stability of large dam whose height is over 40m. Therefore, we assigned the region as safe zone that can be used as a guideline of maintenance of dam. These estimated data can be used in the design, construction and long-term maintenance in domestic CFRD hereafter.

• Proceedings of the KIEE Conference
• /
• 2003.04a
• /
• pp.234-236
• /
• 2003

In this paper, a new control scheme of Class-E inverter for reducing the crest factor of electronic ballasts for fluorescent lamps using Pulse-Frequency-Modulation (PFM) is introduced The lifetime of the lamps is guaranteed by decreasing the lamp crest factor and voltage stress of the switch is significantly decreased by a new scheme although conventional Class-E inverter is used in this paper The proposed PFM control scheme doesn't used any auxiliary circuit. The proposed control strategy is executed by feeding back the input current. and the Zero-Voltage-Switching (ZVS) is ensured by operating beyond resonant frequency. Therefore, the control principles of proposed method are explained in detail and its validity is verified through several simulated results.

• Bulletin of the Korean Chemical Society
• /
• v.29 no.3
• /
• pp.689-692
• /
• 2008

• Journal of Advanced Marine Engineering and Technology
• /
• v.24 no.4
• /
• pp.405-413
• /
• 2000

This paper present study on the application of sound pressure and vibration signals to detect the presence of defects in a rolling element bearing using a statistical analysis method. The well established statistical parameters such as the crest factor and the distribution of moments including kurtosis and skew are utilized in this study. In addition, other statistical parameters derived from the beta distribution function are also used. A comparison study on the performance of the different types of parameter used is also performed. The statistical analysis is used because of its simplicity and quick computation. Under ideal conditions, the statistical method can be used to identify the different types of defect present in the bearing. In addition, the results also reveal that there is no significant advantages in using the beta function parameters when compared to using kurtosis and the crest factor for detecting and identifying defects in rolling element bearings from both sound and vibration signals.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
• /
• 2002.10a
• /
• pp.113-118
• /
• 2002

Wave overtopping is one of the most important hydraulic responses of breakwater because it significantly affects its functional efficiency, the safety of transit and mooring on the rear side, wave transmission in the sheltered area, rear side armor stones and to some extent, the structural safety itself. The hydrodynamic characteristics of low crest breakwater by the overtopping rate can be summarized as follows: 1. It is better to use maximum overtopping rate than to use mean overtopping rate for design of coastal structures. 2. Maximum overtopping rate was increase with wave steepness (between 0.01 and 0.02). 3. Overtopping rate is decreased when relation length of berm was over wave length.

• 한국정보통신설비학회:학술대회논문집
• /
• 2005.08a
• /
• pp.128-132
• /
• 2005

각종 신호의 디지털 전송에서 Modulation기법에 의해 발생되는 PAPR(Peak to Average Power Ratio)은 전송 신호의 선형성을 보장하기 위하여 고출력 증폭기의 Back-off를 요구하게 된다. 이러한 고출력 증폭기의 Back-off요구로 인하여 원하는 출력에 비해 높은 전력소모량이 필요하여 대출력을 요구하는 장비의 소형화는 크게 제한을 받게 된다. 본 논문에서는 PAR을 감소하기 위한 CFR(Crest Factor Reduction)기법을 위성 DMB용 Gap Filler에 적용하여 장비 크기를 소형화한 사례에 대해 소개한다. 전송신호의 품질에 대한 영향을 최소화 하면서 PAR을 감소하기 위한 방안을 위해 도입된 Simulation 결과와 CFR기법을 적용한 장비에 대한 성능시험 결과 및 필드 테스트 결과에 대해 소개한다.

• The Korean Journal of Nuclear Medicine
• /
• v.37 no.3
• /
• pp.171-177
• /
• 2003

PURPOSE: To asess the ability of FDG PET for the detection of bone marrow infiltration compared to iliac crest biopsy in patients with lymphoma. MATERIALS AND METHODS: Seventy-three patients (30 females and 43 males, mean age of 47 years old) with malignant lymphoma (4 Hodgkin's disease, HD and 69 Non-Hodgkin's lymphoma, NHL) were included. FDG PET was performed for staging in 53 patients and to assess treatment response after the completion of chemotherapy in 20 patients. Final conclusions were based on biopsy, other imaging studies, or clinical follow-up. RESULTS: There were 54 (74%) of the 73 patients in whom FDG PET and iliac crest biopsy were concordant. Forty-seven of the 54 patients showed concordant negative results while the remaining 7 patients had concordant positive results. Of 19 patients with discordant results, FDG PET accurately detected bone marrow infiltration in 6 patients with negative iliac crest biopsy. On the contrary, iliac crest biopsy identified bone marrow infiltration in 12 or the 19 patients. In remaining one of the 19 patients with discordant results, iliac crest biopsy was true negative but FDG PET was falsely positive. CONCLUSION: FDG PET seems to be an adjunct in detecting marrow infiltration that may not be revealed by iliac crest biopsy at staging. For the assessment of treatment roponse, it may be less helpful than biopsy in detecting microscopic residual disease in the bone marrow.

• The Korean Journal of Quaternary Research
• /
• v.25 no.2
• /
• pp.25-37
• /
• 2011

The purpose of this study is to assume the particular area of hills where it is highly possible for historical site to be buried in the viewpoint of geomorphology and based on this to suggest excavation-recommended area. Namely, this writer is to understand the dwelling site type of ancient people who had resided there at that time for the object of 'Ohnju region urban development business site' (referred as investigation area hereinafter) and considering the characteristics of micro-landform of hills which are distributed in investigation area and is to recommend the area where it is highly possible for historical site to be buried. The result of analysis is like the following. (1) Dwelling site types of ancient people who might have resided in the whole area of investigation region are discovered to be largely 'low hills+wetland' of Type-I and 'alluvial fan(or river terrace+wetland' of Type-II. (2) In investigation area if the area which has high possibility of distribution of historical site namely, excavation-recommended area is looked as based on micro-landform unit of hills, they are Crest slope and Crest flat. Individual area ratios which Crest slope and Crest flat occupies in investigation area are 12.9% and 10.2% respectively and the rankings are 3 and 6 each. And excavation-recommended areas in valley plain(or bottomland) of investigation area are in the vicinity of 'distal end' or 'buried distal end'of small scale alluvial fan.

• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.28 no.1
• /
• pp.44-52
• /
• 2016

Kelvin's (1887) theory that predicts position of ship wave crest can be applied only in deep water. Havelock's (1907) theory that predicts cusp locus angle can be applied in whole water depths but cannot predict the position of ship wave crest. In this study, using the linear dispersion fully, we develop the equations to predict ship wave crest in whole water depths and, using the developed equations, we predict cusp locus angle. We simulate ship wave propagation using FLOW-3D in the condition of Johnson's (1985) hydraulic experiment and find that the cusp locus angles predicted by the present theory are close to numerical results of FLOW-3D and hydraulic experimental data. We also simulate for various conditions and compare numerical results of distances between adjacent wave crests and values predicted by the present theory. For Froude number less than unity, the numerical results are close to the values predicted by the theory. For Froude number greater than unity, the constant value of $C_1$ which determines the distance between the ship and the first ship wave crest is almost equal to zero and the numerical results of distances between adjacent ship waves excluding the first ship are close to the values predicted by the theory.