• Title/Summary/Keyword: COREX

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in vitro activities of Moutan Cortex Radicis, Caesalpiniae Lignum, Houttuyniae Herba, Forsythiae Fructus, Prunellae Herba, Scrophuiariae Radix against Gardnerella vaginalis (Gardnerella vaginalis에 대한 목단피, 소목, 어성초, 연교, 하고초, 현삼의 항균효과)

  • Zhang, Kyung-Ho;Lee, Dong-Nyung;Kim, Hyung-Jun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.4
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    • pp.1016-1021
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    • 2005
  • The purpose of this thesis is to dedicate to get the objectivity of herbal medicine treatments by choosing herbs likely to work as antibacterial agents, Moutan Cortex Radicis, Caesalpiniae Lignum, Houttuyniae Herba, Forsythiae Fructus, Prunellae Herba, Scrophulariae Radix against Gardnerella vaginalis which is associated with Bacterial vaginosis, making experiments on them and getting the significant results. Each herb's efficacy on control the number of Bacterial vaginosis is noticed by using Disk Susceptibility test with six herbs medicine and Broth dilution assay of the culture. Disk Suseptibility Test : The efficiency strength is as follows in a row : Caesaipiniae Lignum, Moutan Cortex Radicis, Prunellae Herba, Forsythiae Fructus, Houttuyniae Herba, Scrophulariae Radix. MIC Prunellae Herba is 1.5 mg/ml, Caesalpiniae Lignum is 5 mg/ml, Forsythiae Fructus and Moutan Corex Radicis is 10mg/ml for G. vaginalis. As a results, herbmed which tested in this study have an antibacterial effects against G. vaginalis and that may be used for treament of Bacterial vaginosis. Assistant use of external medicine to p.o medicine is expected to bring the good effect of treatment which is used for the origin of this disease.

Antioxidative Activity of Ulmi cortex Extract (유백피(Ulmi cortex) 추출물의 항산화 활성)

  • 이경행;전은경;유시영;오만진
    • Food Science and Preservation
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    • v.7 no.4
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    • pp.373-379
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    • 2000
  • The Ulmi corex extract was prepared using various solvents to investigate the availability as a natural antioxidant. The extracts were added to lard emulsion and the antioxidant activities were compared. The extract that had a greater antioxidant activity was fractionized. Then the antioxidant activity and substrate specificity of the fraction were examined and optimum concentration of addition was determined. To observe the antioxidative effect of the fraction in vivo, an inhibition rate of lipid peroxidation from which might be derived was measured using a microsome in rat's liver. Among the extracts of Ulmi cortex, the extract from water had the best antioxidant activity, and the addition of 0.05% (w/w) of ethyl acetate fraction showed similar antioxidant activity to a synthetic antioxidant, butylated hydroxyanisole(BHA). Ethyl acetate fraction (0.05%, w/w) also presented the antioxidative effect in lard, soybean oil, palm oil, and com oil. The inhibition of lipid peroxidation in liver microsome showed feater in the ethyl acetate fraction than caffeic acid in both nonenzymatic peroxidation (Fe$\^$++/ascorbate system) and enzymatic peroxidation (Fe$\^$++/-ADP/NaDPH system).

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섭제골 지역의 산화지 및 비산화지의 군락구조 비교

  • Sim, Hak-Bo;Kim, Woen
    • The Korean Journal of Ecology
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    • v.16 no.4
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    • pp.429-438
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    • 1993
  • This is a report on the early vegetation and the secondary succession in the burned area of SeobJe-Go1 of $IIwasan-MY\v{o}n,\;Y\v{o}ngch\v{o}n-Gun,\;Ky\v{u}ngsangbuk-do$ Province. The forest fire occurred on April 8, 1982 and the pine forest and its floor vegetation were burned down. The investigation was done six times from August 20, 1982 to August 13, 1983. The results are summarized as follows: the floristic composition of burned areas $B_1,\;B_2$, and unburned areas $U_1,\;U_2$ were composed of 25, 23, 32, and 27 kinds of vascular plants. respectively. The biological spectra showed the $H-D_1-R_5-e$ type in both the burned and unburned areas. The species of Arundinella hirta, Miscanthus simnsis var. purpurascens and Cares hurnilis var. nana were dominant species in the burned area, while Pinus densiflorrr, Corex humilis var. nana and Rhododendron mucronulatum var. ciliafum were dominant species in the unburned area. Degree of succession of the unburned area was comparatively higher than that of the burned area. Species diversity index and evenness index of the burned area were similar to those of the unburned area. Indices of similarity in sampling sites showed that $B_1\;and\;B_2$ stands were the most similar. pH, total nitrogen, available phosphorus and exchangeable potassium of soil increased but organic matter and total organic carbon decreased after fire.

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Antioxidant Effects and Nitrite Scavenging Ability of Extract from Acanthopanax cortex Shoot (오가피순 추출물의 항산화 효과 및 아질산염 소거능)

  • Yu, Seok-Yeong;Lee, Young-Jun;Song, Ho-Seong;Hong, Hee-Do;Lim, Jeong-Ho;Choi, Hyeon-Son;Lee, Boo-Yong;Kang, Suk-Nam;Lee, Ok-Hwan
    • The Korean Journal of Food And Nutrition
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    • v.25 no.4
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    • pp.793-799
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    • 2012
  • This study was conducted to examine the antioxidative effect and nitrite scavenging ability of extract from Acanthopanax cortex shoot. The total phenolic compound and flavonoids contents of extract from Acanthopanax corex shoot were $116.33{\pm}6.09mg\;GAE/g$ and $65.07{\pm}4.10mg\;RE/g$, respectively. Antioxidative activities were measured by various in vitro models such as DPPH radical scavenging activity, FRAP, reducing power, ABTS radical scavenging activity, ORAC assay. This results showed that the extract of Acanthopanax cortex shoot was effective in scavenging radicals and protecting oxidation when assessed various in vitro systems. Similarly, the nitrite scavenging ability of extract was increased in a dose-dependent manner. Moreover, ORAC value at a concentration of $0.1mg/m{\ell}$ was $103.4{\pm}5.6{\mu}M\;TE/g$. Considering high consumer demand beneficial health effects, Acanthopanax cortex shoot can be utilized to develop functional food health-promoting and natural antioxidant agents.

Brain Regions Associated With Anhedonia in Healthy Adults : a PET Correlation Study (정상 성인에서 양전자방출단층촬영을 통해 관찰한 무쾌감증 관련 뇌 영역)

  • Jung, Young-Chul;Seok, Jeong-Ho;Chun, Ji-Won;Park, Hae-Jeong;Lee, Jong-Doo;Kim, Jae-Jin
    • The Korean Journal of Nuclear Medicine
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    • v.39 no.6
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    • pp.438-444
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    • 2005
  • Purpose: Anhedonia has been proposed to be the result of a basic neurophysiologic dysfunction and a vulnerability marker that precede and contribute to the liability of developing schizophrenia. We hypothesized that anhedonia, as a construct reflecting the decreased capacity to experience pleasure, should be associated with decreased positive hedonic affect trait. This study examined the relationship between anhedonia and positive hedonic affect trait and searched for the brain legions which correlate with anhedonia in normal subjects. Materials and Methods: Using $^{18}F$-FDG PET scan, we investigated the brain activity of twenty one subjects during resting state. Questionnaires were administrated after the scan in order to assess the self-rated individual differences in physical/social anhedonia and positive/negative affect traits. Results: Negative correlation between physical anhedonia score and positive affect trait score was significant (Pearson coefficient =-0.440, p<0.05). The subjects physical and social anhedonia scores showed positive correlation with metabolic rates in the cerebellum and negative correlation with metabolic rates in the inferior temporal gyrus and middie frontal gyrus. In addition, the positive affect trait score positively correlated with various areas, most prominent with the inferior temporal gyrus. Conclusion: These results suggest that neural substrates, such as the inferior temporal gyrus and prefrontal-cerebellar circuit, which dysfunction has been proposed to be involved with the cognitive deficits of schizophrenia, may also play a significant role in the liability of affective deficits like anhedonia.