• Sleep Medicine and Psychophysiology
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• v.4 no.2
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• pp.129-139
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• 1997

The data collected to date indicate that sleep-related breathing disorders, including sleep-disordered breathing(sleep apnea) and underlying respiratory system diseases, are one of the important risk factors for cardiovascular dysfunction. Sleep-disordered breathing(sleep apnea) is now recognized as one of the leading causes of systemic hypertension, cardiac arrhythmias, coronary heart disease, pulmonary hypertension, right heart failure, and stroke. Sleep may exert a profound effect on breathing in patients with underlying respiratory system disease including bronchopumonary diseases, chest wall abnormalities, central alveolar hypoventilation syndromes or respiratory neuromuscular disorders. Chronic hypoxia and hypercapnia in these patients may accelerate the development of long term cardiovascular complications such as cardiac arrhythmias, pulmonary hypertension, and right heart failure(cor pulmonale). Several recent studies reported that sleep-related breathing disorders are associated with long-term cardiovascular morbidity and mortality. Careful assessment of respiratory and cardiovascular function in these patients is critical. Aggressive and highly effective treatment of sleep-related breathing disorders using tracheostomy, mechanical ventilation, nasal continuous positive airway pressure therapy(nCPAP), intercurrent oxygen therapy or other interventions can reduce the prevalence of cardiovascular dysfunction and the long-term mortality.

• Journal of Families and Better Life
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• v.1 no.2
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• pp.43-57
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• 1983

The purpose of the study, was to investigate Housewives behavior on how to buy refrigerators and how to use them. Besides, their knowledge and keeping ability of electricity and refrigerator is estimated according to regional differences, their ages, their educational courses, and their income. In the report, W e can see if it is related to the years of married life, numbers of the family, having jobs or not, and numbers of marketing a week. The subjects were 675 mothers of the students in the selected schools, at Seoul, Cheongjoo, and Kwesan gun. They answered to the questionnaire devised for the study. their answers were analyzed in percent to grasp their general trend of electricity and electric Appliance. Chi-square test and F-test are chosen to grasp the Cor-relationships between the related variables. The results are as follows: 1) The average rate of possesing the refrigerators is 84.06%. It shows us that the housewives in Seoul possess the more refrigerators than those in other areas. At ages, form 30 to 40 aged women gave the most refrigerators than any other ages women. It reveals us the high income and high educational housewives have high rate of possessing refrigerators. 2) They answered that they purchased the refrigerators by necessity. we can see their motivation of purchasing them is very reasonable. However, we can see that they do not manage the refrigerators well, because the rate of using them during four seasons is only 12.34%, An age of 20year old housewives mostly purchased the refrigerators at the time of marriage. The women who bought them after marriage answered that they mostly took a consultation with their husbands when they bought the refrigerators. They regarded the trade marks of the manufactures and size of the refrigerators, as they bought them. And most of them bought the refrigerators for cash. 3)At homes in Seoul, the kinds of retained foods in the refrigerator are more than those of the house in the city and in the agricultural town. The high income and high educational housewives tend to retain the more kinds of foods. But there are no significant differences between the essential variables such as the numbers of the family, the housewives having jobs or not, and the numbers of marketing. 4)Generally their knowledge on electricity and the refrigerator is very low. However, it shows the statistically significant differences. the housewives in Seoul have more information about refrigerator than the housewives in agricultural town. At ages , the women less than 29 years old have more information about the refrigerator, and the woman who had university education and high income tend to know much about the refrigerator. 5) The keeping ability of the refrigerator is very good, and there are no significant differences among variables. And also it shows that there is no correlationship between their knowledge and their keeping ability.

• Tuberculosis and Respiratory Diseases
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• v.40 no.6
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• pp.694-699
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• 1993

Background: After the introduction of more potent antituberculous drugs and the nation-wide tuberculosis management the prevalence rate and mortality rate of pulmonary tuberculosis has been reduced continuously. But we still experienced many patients who succumbed to this disease. So we investigated the causes of treatment failure and death of patients with pulmonary tuberculosis to delineate the problems in the management of these patients. Methods: Retrospective analysis of medical records of 55 patients who died of pulmonary tuberculosis in Kyung-Hee University Hospital during the period of Mar. 1979-Feb. 1990. Results: 1) Average duration of illness was $11.9{\pm}10.1$ years. 2) The mortality rate of in-patients with pulmonary tuberculosis was 2.09%. 3) 47.3% of patients had been treated more than twice and the sputum positive rate was 52.7%. 4) Causes of death were acute respiratory failure(56.4%), asphyxia by hemoptysis(14.6%), cor pulmonale(9.1%), tension pneumothotax(7.3%), vital organ involvement(9.1%) and coexisting diseases(3.5%). Conclusion: Many of these patients had long duration of illness, persistant sputum AFB and high incidence of acute respiratory failure as a fatal complication. It seemed that patient's neglect of their disease and inadequate treatment had caused aggravation of tuberculosis.

• Journal of the Korean association of regional geographers
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• v.18 no.3
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• pp.336-350
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• 2012

Cette $\acute{e}$tude a pour objectif d'analyser et d'expliquer le g$\acute{e}$osite de l'$\hat{I}$le de Geum-o pour connaitre les caract$\acute{e}$ristiques de cette r$\acute{e}$gion du point de vue $\acute{e}$cologique, historique et culturel $\grave{a}$ partir de ses ressources g$\acute{e}$omorphiques et g$\acute{e}$ologiques. Il y a plusieurs ressources g$\acute{e}$otouristiques sur $\hat{I}$le de Geum - o: la falaise de 'Miyeokneolbang' et 'Shinseondae'; la plage de Gigpo; la falaise et la caverne marine de 'Gualbaramtong'; le tombolo et l'$\hat{I}$le reli$\acute{e}$e $\grave{a}$ la terre de Choungsan; la coul$\acute{e}$e de roches de Jangji; la plage de cailloux de Jangji; le lieu des tuf et des andesite de la c$\hat{o}$te orientale. On a g$\acute{e}$n$\acute{e}$ralement d$\acute{e}$velopp$\acute{e}$ la couche s$\acute{e}$dimentaire et les roches volcaniques li$\acute{e}$es $\grave{a}$ la derni$\grave{e}$re p$\acute{e}$riode du m$\acute{e}$sozo$\ddot{i}$que. Une route g$\acute{e}$otouristique part de l'embarcad$\grave{e}$re de Hamgoumi sur l'$\hat{I}$le de Geum-o et continue du Nord-Ouest jusqu'au Sud-Est l'autre route part de la c$\hat{o}$te Est et continue en suivant la c$\hat{o}$te orientale. Nous proposons des panneaux d'explication g$\acute{e}$otouristique de Janji centr$\acute{e}$s sur la coul$\acute{e}$e de roches.

• Korean Journal of Plant Tissue Culture
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• v.27 no.3
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• pp.203-211
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• 2000

In this study to produce large-scale scopolamine we were examined in the tumor calli of Datura metel L. induced by Agrobacterium tumefaciens $Ery{101}$. The growth and scopolamine contents of tumor calli were higher under light condition than in dark. The optimum condition of growth and scopolamine production were fluence rate of 16 $\mu$mol $m^{-2}s^{-1}$, spectra of red light region and 16 hour light periods on 50 mL SH liquid medium in 4 weeks culture. To increase of the scopolamine contents in tumor calli, the optimum concentration of nitrogen source were 1.8 mM NH$_4$+ and 40 mM NO$_3$. The optimum elicitor concentration for production of scopolamine were 10 mg/L chitosan and 15 mg/L yeast extract. The effect of precursors were good at the concentration of 0.2 mM tropine and 0.3 mM tropic acid, respectively. In order to increase of growth and scopolamine contents. we induced mutant from Datura metel L. tumor callus. Mutants of tumor calli were obtained by 3 Krad, 4 Krad and 6 Krad of ${60}^Cor-ray$. Among them, 3 Krad tumor callus was excellent on the growth and teratoma induction. The 4 Krad tumor callus was negligible for both growth and teratoma induction. But the 6 Krad tumor callus was the best in growth and teratoma induction. The formation of the mutant calli can be enhanced through hormonal combination of 1 mg/L 2,4-dichlorophenoxyacetic acid and 0.5 mg/L benzyladenine. We carry out selection mutant tumor calli for high content tropane alkaloid and suspension cultures for scopolamine production.

• Bulletin of the Korean Chemical Society
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• v.21 no.10
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• pp.1041-1043
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• 2000

We present the effects of temperature (between 10 K and 298 K) and of hole concentration on the frequency and intensity of characteristic phonons in polycrystalline $La_2CuO_4-related$ compounds using FT-IR spectros-copy. The influences of the concentration of carrier doped on the phonon modes are prominent in the IR spectra of $La_2CuO_4-related$ compounds. For $La_2-xSrxCuO_4({\chi}=$ 0.00, 0.03, 0.07, 0.10, and 0.15) and electrochemically (or chemically) oxidized $La_2CuO_4$, the intensities of the transverse oxygen mode around 680cm $-^1$ which cor-responds mainly to Cu-O(1) stretching vibration in the basal plane of CuO6 octahedron, are decreased and dis-appeared depending on the Sr-substitution rate and the amount of excess oxygen, while the longitudinal oxygen mode around 510 cm $-^1$ corresponding to the Cu-O(2) stretching in the basal plane of CuO6 octahedron are near-ly invariable. In particular, after two cycles of cooling-heating between 10 K and 298 K for these sample, the phonons around 680 cm $-^1$ are blue shif 13-15 cm $-^1$, while the phonons around 510 cm $-^1$ are nearly constant. The introduction of the charge carrier by doping would give rise to the small contraction of CuO6 oc-tahedron as Cu $^3+$ requires a smaller site than Cu $^2+$, which results in the shortening of the Cu-O(1) bond length and Cu-O(2) bond length with the increased La-O(2) bond length. These results in the frequency shift of the characteristic phonons. The IR spectra of $La_2Li0.5Cu0.5O_4$ which exhibits an insulator behavior despite the $Cu^3+$ of nearly 100%, corroborate our IR interpretations. The mode around 710 cm $-^1$ corresponding to Cu-O(1) stretching vibration is still strongly remained even at low temperature (10 K). Thus, we conclude that the con-duction electrons formed within $CuO_2$ planes of $La_2CuO_4-related$ superconductors screen more effectively the transverse oxygen breathing mode around 680 $cm-^1$ depending on the concentration of the doped charge carrier in $La_2CuO_4-related$ compounds, which might use as a superconductivity probe.

• Journal of Gastric Cancer
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• v.21 no.2
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• pp.191-202
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• 2021

Purpose: A near-infrared (NIR) fluorescence imaging is a promising tool for cancer-specific image guided surgery. Human epidermal receptor 2 (HER2) is one of the candidate markers for gastric cancer. In this study, we aimed to synthesize HER2-specific NIR fluorescence probes and evaluate their applicability in cancer-specific image-guided surgeries using an animal model. Materials and Methods: An NIR dye emitting light at 800 nm (IRDye800CW; Li-COR) was conjugated to trastuzumab and an HER2-specific affibody using a click mechanism. HER2 affinity was assessed using surface plasmon resonance. Gastric cancer cell lines (NCI-N87 and SNU-601) were subcutaneously implanted into female BALB/c nu (6-8 weeks old) mice. After intravenous injection of the probes, biodistribution and fluorescence signal intensity were measured using Lumina II (Perkin Elmer) and a laparoscopic NIR camera (InTheSmart). Results: Trastuzumab-IRDye800CW exhibited high affinity for HER2 (K_D=2.093(3) pM). Fluorescence signals in the liver and spleen were the highest at 24 hours post injection, while the signal in HER2-positive tumor cells increased until 72 hours, as assessed using the Lumina II system. The signal corresponding to the tumor was visually identified and clearly differentiated from the liver after 72 hours using a laparoscopic NIR camera. Affibody-IRDye800CW also exhibited high affinity for HER2 (K_D=4.71 nM); however, the signal was not identified in the tumor, probably owing to rapid renal clearance. Conclusions: Trastuzumab-IRDye800CW may be used as a potential NIR probe that can be injected 2-3 days before surgery to obtain high HER2-specific signal and contrast. Affibody-based NIR probes may require modifications to enhance mobilization to the tumor site.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.38 no.6
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• pp.697-705
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• 2020

This paper deals with an analysis of crustal movement for the sourthern part of Korean peninsula using GNSS (Global Navigation Satellite System) data. An earthquake of more than 5.0 occurred in the southeastern region of the Korean Peninsula, and it is necessary to evaluate the risk of earthquakes in various ways.In order to reveal long-term tectonic movement patten in Pohang and Gyeongju provinces, we derived crustal movement parameters related with elastic theory. We used GAMIT/GLOBK for analyzing seven-year interval GNSS data of CORS (Continuously Operating Reference Stations). The azimuth of velocity vectors trended generally about 110° with an mean magnitude of 31mm/yr.The main characteristics of the strain change for seven-year in Korea obtaind from our study. Direction of the principal axis of the maximum compression is ENE-WSW as a whole, through there are some exceptions. The mean rate of the maximum shear strain change is (0.11±0.07)μ/yr, that is approximately one third that of Chubu district, Central Japan. Taking into account our results, the mean rate of maximum shear in southern part of Korean peninsula is considered as reasonable. The mean azimuth of principal strain is about (85.4°±26.8°). There are some exceptions of azimuth because the average azimuth differ from the left and right side in Yangsan fault which are about (73.2°±21.5°) and (105.2°±17.0°) respectively, It is noteworthy that the high seismicity areas in the southern part of Korea peninsula almost coincides with the area of large strain rate. As a conclusion, it could be stated that the our study represents the characteristics of crustal deformation in the southern part of peninsula, and contributes to the researches on earthquake disaster management.

• Journal of Wetlands Research
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• v.25 no.2
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• pp.132-144
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• 2023

The use of constructed wetlands (CWs) to sequester carbon has been a topic of interest in recent studies. However, CWs have been found to be both carbon sinks and carbon sources, thus leaving uncertainties about their role in carbon neutrality initiatives. To address the uncertainties, a bibliometric and comprehensive review on carbon sequestration in CWs was conducted. Upon forming various scripts using CorText Manager, it was found that a majority of the studies focused on the effectiveness of CWs to remove nutrients, particularly nitrogen. The results of the comprehensive review revealed that high carbon concentrations and carbon sequestration rates in CW soils are dependent on the vegetation types used, the ages of the CWs, and the organic content of inflow water entering the CWs. The Typha genus was the most dominant plant genus used in the CWs from the reviewed studies and was associated with the highest carbon sequestration rates documented in this review study. Furthermore, the relatively high ability of tree species, in comparison to emergent plants, to sequester carbon was observed. Therefore, incorporating tree species into CW designs and adding them to emergent plants is seen as a potential breakthrough approach to improve the ability of CWs to sequester carbon and ultimately contribute to mitigating climate change.

• Journal of the Korean Association of Geographic Information Studies
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• v.3 no.3
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• pp.12-19
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• 2000

Knowledge for reflectance characteristic of interesting targets will provide us with actual application of remote sensing on agriculture. In this study, we have measured and analyzed reflectivity characteristics based on growing status from transplanting time to harvesting time. Rice paddies transplant into 3 fields at 20, May, 1999. Measurement of reflectivity characteristics were carried out with a portable spectroradiometer for frequencies from 300nm to 1100nm during the time period from 11:00 AM to 01:00 PM of clear sky and calm a day. The measurements for a day repeated 3 times(also, 3 times to each measurement)for reliable values. In result, we found that averaged reflectivity of visible range has about 2.34% - 2.55% in blue region(400nm-498nm), about 5.05% - 6.01% in green region(500nm-598nm) and about 4.21% - 5.24% in red region(600nm-698nm). It must be noted that the more rice canopy grows, the more spectral reflectivity decreases in visible region. Also, we separated infrared region into two cases - One case is increasing region with 700nm-780nm, the other is fixed region with 800nm-1100nm. Averaged reflectivity of these regions has about 22.3% - 23.0% in increasing region, about 29.4% - 33.1% in fixed region. It must be noted that more rice canopy grows, the more spectral reflectivity also increases up to 23, Aug. in infrared region. After 23, Aug, the reflectivity has a tendency toward decrease.