• 한국정밀공학회지
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• 제30권3호
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• pp.349-355
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• 2013

Recent high oil price results in the development of energy saving technology such as LED lighting system. Street-lighting system using COH LED package can save energy because the heat dissipation through cupper base is better than conventional technology. Studies on manufacturing processes of lighting system are insufficient even though LED package design and its heat analysis have been studied. This study focuses on the problem and solution of manufacturing processes such as LED packaging process, optimized emission angle, and LED bar dimension for mechanical assembly. As a result, we established better manufacturing alternatives of LED packaging and street-lighting system with higher lighting efficiency of 84 lm/W, as well as good illumination intensity of 39.7 lux at 6 m from lighting source.

• 한국산학기술학회논문지
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• 제12권11호
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• pp.5117-5122
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• 2011

본 논문에서는 열 해석 시뮬레이션 프로그램인 COMSOL Multiphysics를 활용하여, LED Module의 제작 시, 가장 선호되는 패키지 종류인 COB Type과 보드를 생략한 COH Type의 열 해석 시뮬레이션을 진행한다. LED Module의 시뮬레이션 결과 방열판을 통과하는 위치에 따라 COB Type은 Max. 약 $78^{\circ}C$ ~ Min. 약 $62^{\circ}C$, COH Type은 Max. 약 $88^{\circ}C$ ~ Min. 약 $67^{\circ}C$에서 온도가 안정이 됨을 확인하였다. COB Type과 비교하여 Max. 온도는 약 $10^{\circ}C$ 차이가 나지만, Min. 온도에서 약 $5^{\circ}C$정도로 격차가 감소함을 확인하였으며, LED Point 온도특성곡선을 확인 한 결과 COB Type은 Max. 약 $100^{\circ}C$ ~ Min. 약 $77^{\circ}C$, COH Type은 Max. 약 $100^{\circ}C$ ~ Min. 약 $86^{\circ}C$온도가 안정이 됨을 확인하였으며, COB Type에 비해 COH Type이 약 $10^{\circ}C$ 온도가 높게 측정되었다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2012년도 춘계학술대회 논문집
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• pp.799-800
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• 2012

• Clinical and Experimental Reproductive Medicine
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• 제29권1호
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• pp.45-56
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• 2002

Objectives: Recently, recombinant FSH (rFSH) has been manufactured using a Chinese hamster ovary cell line transfected with the gene encoding human FSH. Both rFSH and urinary gonadotropin (uFSH) could be used for controlled ovarian hyperstimulation (COH). However, uFSH implies a number of disadvantages, such as batch-to-batch inconsistency, no absolute source control, dependence on large amounts of urine, low specific activity, and low purity. The purpose of this study was to evaluate the efficacy of rFSH in human IVF-ET program. Materials and Methods: A total of 508 infertile women was enrolled in this study. They are classified into rFSH group (n=177) or uFSH group (n=331), and all of them were matched by age and cause of infertility in same period. The $Puregon^{(R)}$ (Organon, Holland) was used as rFSH, and the Metrodin-$HP^{(R)}$ (Serono, Switzeland) and $Humegon^{(R)}$ (Organon, Holland) was used as uFSH. We subdivided the patients into three age groups. The outcomes of IVF-ET program were analyzed using the statistical package for social sciences (SPSS). Results: There was no significant differences in the level of estradiol on hCG injection day, the numbers of retrieved oocytes, matured oocytes, fertilized oocytes, transferred embryos, frozen embryos between the two groups. The total dose (IU) of gonadotropin for COH was significantly lower in the rFSH group compared to uFSH group ($1339{\pm}5491.1$ vs $2527.8{\pm}1075.2$ IU, p<0.001). Clinical pregnancy rate per embryo transfer in the rFSH group showed increasing tendency, compared to the uFSH group, but there was no statistical significance (35.2% vs 29.3%). Our results demonstrated that the relative efficiency of rFSH compared with uFSH is higher in older patients. Conclusions: The ovarian stimulatory effect and clinical outcome of recombinant FSH was similar to that of the urinary gonadotropin. The IVF-ET cycles with significantly lower dose of gonadotropin in rFSH group showed comparable results. Therefore, we suggest that recombinant FSH is more potent and effective than urinary gonadotropin.