• Title/Summary/Keyword: CO2 Rate

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Bioconversion of Ginsenoside Rb1 to the Pharmaceutical Ginsenoside Compound K using Aspergillus usamii KCTC 6954 (Aspergillus usamii KCTC 6954에 의한 ginsenoside Rb1로 부터 의약용 소재인 compound K로의 생물학적 전환)

  • Jo, Mi Na;Jung, Ji En;Yoon, Hyun Joo;Chang, Kyung Hoon;Jee, Hee Sook;Kim, Kee-Tae;Paik, Hyun-Dong
    • Microbiology and Biotechnology Letters
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    • v.42 no.4
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    • pp.347-353
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    • 2014
  • ${\beta}$-Glucosidase from Aspergillus usamii KCTC 6954 was used to convert ginsenoside Rb1 to compound K, which has a high bio-functional activity. The enzymatic activities during culturing for 15 days were determined using ${\rho}$-nitrophenyl-${\beta}$-glucopyranoside. The growth rate of the strain and the enzymatic activity were maximized after 6 days (IU; $175.93{\mu}M\;ml^{-1}\;min^{-1}$). The activities were maximized at $60^{\circ}C$ in pH 6.0. During culturing, Rb1 was converted to Rd after 9 d and then finally converted to compound K at 15 d. In the enzymatic reaction, Rb1 was converted to the ginsenoside Rd within 1 h of reaction time and compound K could be detected after 8 h. As a result, this study demonstrates that $Rb1{\rightarrow}Rd{\rightarrow}F2{\rightarrow}$compound K is the main metabolic pathway catalyzed by ${\beta}$-glucosidase and that ${\beta}$-glucosidase is a feasible option for the development of specific bioconversion processes to obtain minor ginsenosides such as Rd and compound K.

A STUDY ON THE CORROSION BEHAVIOUR OF AMALGAMS BY USING OF POTENTIOSTATIC POLARIZATION METHOD (정전압 분극곡선법에 의한 아말감의 부식 거동에 관한 연구)

  • Shin, Dong-Hoon;Um, Chung-Moon
    • Restorative Dentistry and Endodontics
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    • v.12 no.1
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    • pp.39-49
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    • 1986
  • The purpose of this study was to observe characteristic properties through the polarization curves and SEM images from 4 different types of amalgam obtained by using the potentiostats (Princeton EG & G) & SEM (Jeol/35), and to investigate the degree of corrosion on the oxidation peak of the each phase of amalgam. After each amalgam alloy and Hg was triturated as the direction of the manufacturer by means of the mechanical amalgamator (Shofu Co.), the triturated mass was inserted into the cylindrical metal mold which was 12mm in diameter and 10.0mm in height and was condensed by using routine manner. The specimen was removed from the mold and stored at room temperature for about 24 hours. The standard surface preparation was routinely carried out. Anodic polarization measurement was employed to confirm the corrosion behaviour of the amalgams in a 0.9% saline solution (P.H: 6.8-7.0) at $37^{\circ}C$. The initial rest potential (corrosion potential) was determined after 30 minutes of immersion of specimen in electrolyte, and the potential scan was begun at the point of 100mV cathodic from the corrosion potential. The scan rate was 0.17mV/sec. in the study to observe the degree of corrosion of each phase. SEI and EPMA images on the determined oxidation peaks of each amalgam were observed. The results were as follows: 1. In the four anodic polarization curves, low copper amalgams have three oxidation peaks and high copper amalgams have two oxidation peaks, -270mV, +26mV and +179mV(SEC) in the low copper lathe cut, and -300mV, +39mV and +163mV(SEC) in the low copper spherical. -4mV and +154mV(SEC) in the Dispersalloy, and +17mV and +180mV(SEC) in the Tytin as high copper amalgams. 2. ${\gamma}_2$ phase in the low copper amalgam and ${\eta}$ phase in the high copper amalgam were the most corrodible phases and Ag-Cu eutectic in high copper amalgam was the most slowly corroded phase. 3. Low copper amalgam was more susceptible in corrosion than high copper amalgam.

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A Study on Evaluation System of Track Support Stiffness for Concrete Tracks (콘크리트궤도의 궤도지지강성 평가시스템에 관한 연구)

  • Choi, Jung-Youl;Kim, Man-Hwa;Kim, Hyun-Soo;Chung, Jee-Seung
    • The Journal of the Convergence on Culture Technology
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    • v.6 no.2
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    • pp.535-541
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    • 2020
  • A conventional elastic material replacement and performance evaluation are very complicated and time-consuming, and it is difficult to know when to replace the elastic material in advance. By comparing with the product limit and the functional limit, the necessity of elastic material replacement and the improvement of track support stiffness according to replacement can be immediately demonstrated based on experimental data. Using an evaluation system of track support stiffness, the performance evaluation data for elastic materials obtained through field tests using software for track support stiffness is integrated and managed on the administrator's computer. Therefore, the replacement plan is established and maintenance history is managed by identifying the replacement time and location of elastic materials. It is possible to evaluate the performance and condition of the elastic material at the various points during the working time of the track inspection and the track performance (track support stiffness) and durability of the elastic material (aging level, spring stiffness variation rate, etc.) at the operation condition. The elastic material could be replaced timely, and the deterioration of the elastic material can be continuously monitored.

Pharmacokinetics of Anticancer Agent SB-31 in Rats & Rabbits and the Cardiovascular Effect on the Isolated Perfused Rat Heart & Blood Coagulation (SB-31의 Glycyrrhizin을 지표로 한 Rat과 Rabbit에서의 약물동태 및 심혈관계에 대한 효과 연구)

  • Kang, Won Ku;Park, Yong Soon;Lee, Dong Heum;Kwon, Kwang Il
    • Korean Journal of Clinical Pharmacy
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    • v.8 no.2
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    • pp.122-132
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    • 1998
  • SB-31 which contains Pursatilla, Licoris and Ginseng extracts was recently proved as an anticancer agent. In a preclinical effort to be applied this drug to human, pharmacokinetics of SB-31 was carried out in rats and rabbits. Glycyrrhizin(GZ), a saponin of Licoris was used as a standard ingradient for the pharmacokinetics of SB-31. The rat's blood, bile and urine samples were serially collected in femoral vein, common bile duct and bladder, respectively, after bolus i.v. injection at a dose of 1 or 1/5 ampul/rat and rabbit's blood samples from the marginal ear vein at a dose of 1 or 3 amp./rabbit. GZ and glycyrrhetic acid(GA), a major metabolite of GZ in the physiological samples were analysed by HPLC with UV detection. The decline of GZ in plasma concentration was generally biexponential at each dose. GZ was almost completely recovered in bile within 18 hour. GA wasn't detected in the samples with UV detector. In the rat, Vss and Kel at a dose of 1 and 1/5 ampul of SB-31 were $98.06\pm6.07\;ml,\;0.33\pm0.05\;hr^{-1}\;and\;65.46\pm11.19\;ml,\;0.68\pm0.25\;hr^{-1}$, respectively. Those in rabbits at a dose of 3 and 1 ampul of SB-31 were $235.24\pm30.72\;ml,\;0.13\pm0.36\;hr^{-1}\;and\;341.32\pm28.58\;ml,\;0.27\pm0.04\;hr^{-1}$, respectively. 'WinNonlin' was utilized for the compartmental analysis. A two-compartment model was chosen as the most appropriate pbarmaco-kinetic model. The data were best described by using a weighting factor of $1/y^2$. To evaluate the effect of SB-31 on cardiovascular system, serially diluted SB-31 was directly injected into coronary artery in the isolated perfused rat heart and the effect of PSF, PSH, saponins of Pursatilla, and SB-31 on PT, APTT of healthy human plasma was examined. Except the positive inotropic effect of ten times diluted solution of SB-31, there was no significant effect on LVDP, (- dp/dt)/(+dp/dt), heart rate and coronary flow in comparision with that of vehicle. SB-31 had no effect on PT but slightly delayed APTT about $6.9{\sim}11.5\%$. There was no significant effect of PSF and PSH on PT & APTT. Conclusively, SB-31 did not show any notable toxic effects on cardiovascular system.

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Comparison of Phytoncide (monoterpene) Concentration by Type of Recreational Forest (산림휴양지 유형에 따른 피톤치드(모노테르펜) 농도 비교)

  • Lee, Yong-Ki;Woo, Jung-Sik;Choi, Si-Rim;Shin, Eun-Sang
    • Journal of Environmental Health Sciences
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    • v.41 no.4
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    • pp.241-248
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    • 2015
  • Objectives: This study was conducted to provide scientific and effective information on phytoncides, which are associated with forest healing, and to activate recreational forests. Methods: The target sites were natural recreation forests, a forest park and an arboretum, and the control sites were three urban parks. The samples were collected at a volume of 6.0 L and a flow rate of 0.1 L/min for one hour using a low volume pump and the solid adsorbent sampling method. The phytoncide compounds adsorbed in the Tenax TA tube were analyzed by a automatic heat desorption unit and GC-MS. Results: By type of recreational forest, the annual concentrations of phytoncide (monoterpene) for the forest park showed the highest concentration with $1.450{\mu}g/m^3$, while those for the arboretum showed the lowest concentration at $0.892{\mu}g/m^3$, and thus the concentration of the forest park was approximately 1.6 times higher than the arboretum. The season showing the highest concentration of phytoncides was summer (June) and the forest park was the highest among the recreational forests. The concentrations of major components for phytoncide showed in descending order: ${\alpha}-pinene$, ${\beta}-pinene$, camphene, 3-carene and limonene. The seasonal concentration of ${\alpha}-pinene$, camphene and ${\beta}-pinene$ by type of recreational forest increased in April, which is characterized by low temperature and humidity, and the seasonal concentration of camphene decreased with higher humidity. The meteorological factors which had the high correlation with the concentration of total terpene were temperature and humidity. $CO_2$ and $O_2$ showed an inverse correlation. Conclusion: The major components of phytoncide were ${\alpha}-pinene$, ${\beta}-pinene$, camphene, 3-carene and limonene in descending order of concentration. Further and systematic study on the chemical nature of individual phytoncides, and on the effect of phytoncides on humans needs to be performed.

Selection of Systemic Chemicals and Attractiveness of Sunflower to Ricania spp.(Hemiptera: Ricaniidae) Adults (갈색날개매미충 성충에 대한 해바라기의 유인력과 침투이행성 약제 선발)

  • Choi, Yong-Seok;Seo, Hwa-Young;Jo, Shin-Hyuk;Whang, In-Su;Park, Deog-Kee
    • Korean journal of applied entomology
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    • v.56 no.4
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    • pp.345-350
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    • 2017
  • Sunflower, selected as a trap plant that can be controlled by attracting Ricania spp. adults via attraction has the highest attractiveness during the preoviposition period. Considering the ecological characteristics of Ricania spp., adults are distinguished by the preoviposition and oviposition periods and the attractiveness of sunflower to Ricania spp. adults was 91.4~95.2% higher than that of blueberry during the preoviposition period. On August 20, when Ricania spp. adults entered the oviposition season, sunflower attractiveness was low at 9.8~11.6% owing to preference for tree species. Based on the result of the selection of systemic chemicals that could be used concomitantly with sunflower, all chemicals, except etofenprox, showed a high controlling effect of over 90%, and among them, dinotefuran showed the highest insecticidal rate of 95.8%. The systemic chemicals acetamiprid, dinotefuran, thiamethoxam, and imidacloprid persisted for 13 days (survey period). Therefore, the concomitant use of sunflower and systemic chemicals can reduce the density of Ricania spp. entering farmlands and their populations in surrounding habitats, which are expected to help in stabilizing the ecosystem.

Optimization of Optical Structure of Lightguide Panel for Uniformity Improvement of Edge-lit Backlight (엣지형 LED 백라이트의 균일도 향상을 위한 도광판의 광구조 최적화)

  • Lee, Jung-Ho;Nahm, Kie-Bong;Ko, Jae-Hyeon;Kim, Joong-Hyun
    • Korean Journal of Optics and Photonics
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    • v.21 no.2
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    • pp.61-68
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    • 2010
  • Optical simulation methods were applied to the edge-lit LED backlight for LCD TV applications in order to optimize the optical structure of the light guide plate(LGP), and thus to improve the uniformity properties by removing the bright spots caused by LED's. The edge-lit LED backlight consisted of three white LED's with a lamp cover, a light guide plate, and a reflection film. When there was no pattern on the entrance side surface of the LGP, the illuminance uniformity was sensitively dependent on the distance d between the LED and the entrance surface. The illuminance uniformity increased with d but its increasing rate slowed down when d was beyond ~ 1.5 mm. When micro-patterns such as a lenticular lens array (LLA) or a serration pattern were formed on the entrance surface, the illuminance uniformity was improved substantially even for the case of very small d. At the same simulation condition, the lightguide with serration pattern showed a better uniformity than that with LLA pattern. Additional improvement could be achieved by changing the refractive index of the micro-patterns. These results suggest that using micro-patterns is a very effective way to reduce the bright spots due to their refracting function for the concentrated incident rays onto the LGP.

Green Productivity Analysis of the Logistics Industry for the Global Competitiveness (물류산업의 녹색생산성 평가와 국제경쟁력 강화방안)

  • Choi, Yong-Rok
    • International Commerce and Information Review
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    • v.14 no.4
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    • pp.89-107
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    • 2012
  • Recently, the successful appointment of the general directorate of GCF (Green Climate Fund) in Songdo of Korea made a great history for the golden triangle with GGGI (global Green Growth Institute) and GTC (Green Technology Center). Now, Korea became the Mecca for the global green growth and it gave a great opportunity foe the Korea to lead the global economy in the future. However, to successfully manage the GCF, the Korean government should show their willingness as well as the readiness for the green prowth and green productivity. It is really hard for the Korea, since it takes the second rank for the growth rate of carbon dioxide emission in the world. To overcome this shameful status, it should make the best effort to promote the green productivity, especially in a field of logistics industry, because it takes 21% of global CO2 emission, the second largest portion. The research aims to systematically introduce the Global Malmquist-Luenberger Index (GML) and to evaluate the logistics industry of Korea based on the GML approach. It concludes the innovative technology is utmost important to improve the green productivity of the logistics industry and thus the Korean government should make more aggressive role to fill this missing link in the innovation network.

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Development of Sludge Concentration Estimation Method using Neuro-Fuzzy Algorithm (뉴로-퍼지 알고리즘을 이용한 슬러지 농도 추정 기법 개발)

  • Jang, Sang-Bok;Lee, Ho-Hyun;Lee, Dae-Jong;Kweon, Jin-Hee;Chun, Myung-Geun
    • Journal of the Korean Institute of Intelligent Systems
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    • v.25 no.2
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    • pp.119-125
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    • 2015
  • A concentration meter is widely used at purification plants, sewage treatment plants and waste water treatment plants to sort and transfer high concentration sludge and to control the amount of chemical dosage. When the strange substance is contained in the sludge, however, the attenuation of ultrasonic wave could be increased or not be transmitted to the receiver. At that case, the value of concentration meter is higher than the actual density value or vibrated up and down. It has also been difficult to automate the residuals treatment process according to the problems as sludge attachment or damage of a sensor. Multi-beam ultrasonic concentration meter has been developed to solve these problems, but the failure of the ultrasonic beam of a specific concentration measurement value degrade the performance of the entire system. This paper proposes the method to improve the accuracy of sludge concentration rate by choosing reliable sensor values and learning them by proposed algorithm. The prediction algorithm is chosen as neuro-fuzzy model, which is tested by the various experiments.

A review of analytical method for volatile fatty acids as designated offensive odorants in Korea (악취성 유기지방산 성분의 분석기술)

  • Ahn, Ji-Won;Kim, Yong-Hyun;Kim, Ki-Hyun;Song, Hee-Nam
    • Analytical Science and Technology
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    • v.25 no.2
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    • pp.91-101
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    • 2012
  • A list of volatile fatty acids (VFA) including propionic acid, butyric acid, isovaleric acid, valeric acid, etc. is well known for offensive odorants. The analysis of odorant VFA is a highly delicate task due to high reactivity and unstable recovery rate. At present, analytical methods of VFA are recommended to include alkali impregnation filter method and alkali absorption method by the malodor prevention law of the Korea Ministry of Environment (KMOE). In this review, a survey has been made to explore various approaches available for the analysis of VFA to include both official methods of the KMOE and others. In light of the unreliability of those established analytical methods, it is highly desirable to develop some substituting methods for VFA. Among such options, one may consider such option as sorbent tube (ST) sampling and cryogenic trapping-thermal desorption technique. Moreover, procedures used for standard preparation, sampling steps, and instrumental detection stage are also evaluated. Application of container sampling (like Tedlar bag) is however not recommendable due to significant (sorptive) loss in sampling and in storage stage. In the detection stage, the use of GC/MS is recommendable to replace GC/FID due to the presence of diverse interfering substances. Thus, it is essential to properly establish the basic quality assurance (QA) for VFA analysis in air.