• 제목/요약/키워드: CMT1A

검색결과 118건 처리시간 0.031초

ANN Synthesis Models Trained with Modified GA-LM Algorithm for ACPWs with Conductor Backing and Substrate Overlaying

  • Wang, Zhongbao;Fang, Shaojun;Fu, Shiqiang
    • ETRI Journal
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    • 제34권5호
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    • pp.696-705
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    • 2012
  • Accurate synthesis models based on artificial neural networks (ANNs) are proposed to directly obtain the physical dimensions of an asymmetric coplanar waveguide with conductor backing and substrate overlaying (ACPWCBSO). First, the ACPWCBSO is analyzed with the conformal mapping technique (CMT) to obtain the training data. Then, a modified genetic-algorithm-Levenberg-Marquardt (GA-LM) algorithm is adopted to train ANNs. In the algorithm, the maximal relative error (MRE) is used as the fitness function of the chromosomes to guarantee that the MRE is small, while the mean square error is used as the error function in LM training to ensure that the average relative error is small. The MRE of ANNs trained with the modified GA-LM algorithm is less than 8.1%, which is smaller than those trained with the existing GA-LM algorithm and the LM algorithm (greater than 15%). Lastly, the ANN synthesis models are validated by the CMT analysis, electromagnetic simulation, and measurements.

SMART-ITL 1 계열 피동안전계통을 이용한 유동분사기 성능에 대한 실험연구 (An Experimental Study on Flow Distributor Performance with Single-Train Passive Safety System of SMART-ITL)

  • 류성욱;배황;양진화;전병국;윤은구;김재민;방윤곤;김명준;이성재;박현식
    • 에너지공학
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    • 제25권4호
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    • pp.124-132
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    • 2016
  • 노심보충탱크 상부에 설치되는 유동분사기 형상에 따른 냉각수 주입특성 및 탱크 내에서의 열수력 현상 변화를 파악하기 위한 안전주입배관 2인치 파단 소형냉각재상실사고(SBLOCA) 모의시험이 잔열 및 피동잔열제거계통(PRHRS) 모의 없이 수행되었다. 두 가지 형상의 유동분사기를 설치하고 수행한 각각의 시험은 거의 유사한 초기 및 경계조건에서 수행되었으며, 이로 인해 반복시험에 대한 재현성이 충족되었다고 판단된다. 시험결과는 유동분사기의 종류(본 시험에서는 구멍의 개수에 해당)에 관계없이 유사한 열수력학적 거동을 보였으며, 초기 주입유량 관점에서는 구멍의 개수가 2배인 B형이 A형에 비해 좀 더 우수한 주입 성능을 보였다. 노심보충탱크 격리 밸브가 개방된 후 압력평형배관을 통해 유입되는 고온의 원자로냉각재는 상부 헤더에서 상대적으로 저온인 $50^{\circ}C$ 물과 혼합되면서 증기 응축과 같은 상변화에 의한 압력 변동을 동반하는 다차원 열유동 현상을 일으키게 된다. 이로 인해 초반부 노심보충탱크 주입 유량은 상온운전 조건에서 보다는 작게 되고, 일정시간 경과 후에는 유사한 주입유량 특성을 보였다.

SMART-ITL 1 계열 피동안전계통을 이용한 안전주입배관 파단 소형냉각재상실사고 모의에 대한 실험적 연구 (Experimental Study of SBLOCA Simulation of Safety-Injection Line Break with Single Train Passive Safety System of SMART-ITL)

  • 류성욱;배황;유효봉;변선준;김우식;신용철;이성재;박현식
    • 대한기계학회논문집B
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    • 제40권3호
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    • pp.165-172
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    • 2016
  • 노심보충탱크(Core Makeup Tank, CMT), 안전주입탱크(SafetyInjection Tank, SIT)와 자동감압계통(Auto Depressurization System, ADS)로 구성된 1 계열의 SMART 피동안전주입계통의 주입특성을 파악하기 위한 소형냉각재상실사고(SBLOCA) 모의에 대한 실험적 연구가 수행되었다. SBLOCA의시험은 0.4 인치 안전주입수 배관파단에 대해 수행되었으며, 정상상태 조건은 실험요건서에 제시된 시험 초기 조건을 만족시키도록 746초 동안 운전되었다. 노심 출력 및 안전주입 유량 등의 경계 조건도 적절히 모의되었으며, 안전주입계통 배관에서의 파단, 히터 트립 및 잔열곡선 인가, 원자로냉각재펌프 관성서행(Coastdown), 급수 중단, CMT 및 SIT의 주입, ADS #1 개방이 SBLOCA 시나리오에 따라 적절히 모의되었다. 노심지지원통 내부의 액체환산수위는 파단 초반에 감소하다가 CMT와 SIT가 주입되면서 서서히 회복되었으며, 피동안전주입계통의 주입유량이 노심 수위를 회복하기에 충분한 것으로 판단할 수 있다.

Influence of Injection Rate Shaping on Combustion and Emissions for a Medium Duty Diesel Engine

  • Benajes, J.;Molina, S.;Rudder, K. De;Rente, T.
    • Journal of Mechanical Science and Technology
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    • 제20권9호
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    • pp.1436-1448
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    • 2006
  • This paper describes the effects of injection rate shaping on the combustion, fuel consumption and emission of $NO_x$ and soot of a medium duty diesel engine. The focus is on the influence of four different injection rate shapes, square type 1, square type 2, boot and ramp, with a variation of maximum injection pressure and start of injection (SOI). The experiments were carried out on a 1 liter single cylinder research diesel engine equipped with an amplifier-piston common rail injection system, allowing the adjustment of the injection pressure during the injection event and thus injection rate as desired. Two strategies to maintain the injected fuel mass constant were followed. One where rate shaping is applied at constant injection duration with different peak injection pressure and one strategy where rate shaping is applied at a constant peak injection pressure, but with variable injection duration. Injection rate shaping was found to have a large effect on the premixed and diffusion combustion, a significant influence on $NO_x$ emissions and depending on the followed strategy, moderate or no influence on soot emission. Only small effects on indicated fuel consumption were found.

염색체 17p11.2 유전자 결손을 동반한 유전성 압박마비 편향 신경병증의 임상적, 전기생리학적 특성 (Clinical and Electrophysiological Features of HNPP Patients with 17p11.2 Deletion)

  • 홍윤호;김만호;성정준;김성훈;이광우
    • Annals of Clinical Neurophysiology
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    • 제4권2호
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    • pp.125-132
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    • 2002
  • Objectives : Although the diagnosis of hereditary neuropathy with liability to pressure palsies (HNPP) is important for correct prognostic evaluation and genetic counseling, the diagnosis is frequently missed or delayed. Our main aim on undertaking this study was to characterize the electrodiagnostic features of HNPP. Material and Methods : Clinical, electrophysiologic and molecular studies were performed on Korean HNPP patients with 17p11.2 deletion. The results of electrophysiologic studies were compared with those of Charcot-Marie-Tooth disease type 1A (CMT1A) patients carrying 17p11.2 duplication. Results : Eight HNPP (50 motor, 39 sensory nerves) and six CMT1A (28 motor, 16 sensory nerves) patients were included. The slowing of sensory conduction in nearly all nerves and the distal accentuation of motor conduction abnormalities are the main features of background polyneuropathy in HNPP. In contrast to CMT1A, where severity of nerve conduction slowing was not different among nerve groups, HNPP sensory nerve conduction was more slowed in the median and ulnar nerves than in the sural nerve (p<0.01), and DML was more prolonged in the median nerve than in the other motor nerves (p<0.01). TLIs were significantly lower in HNPP than in the normal control and CMT1A patients for the median and ulnar nerves (p<0.01), and were also significantly reduced for the peroneal nerve (p<0.05) compared with those of the normal controls. Conclusion : The distribution and severity of the background electrophysiologic abnormalities are closely related to the topography of common entrapment or compression sites, which suggests the possible pathogenetic role of subclinical pressure injury at these sites in the development of the distinct background polyneuropathy in HNPP.

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유질개선을 통한 낙농가 소득증대 - SCC와 유방염을 중심으로- (Increacing profit of dairy farm through improvement of raw milk quality : According to SCC and mastitis)

  • 손봉환;최진영;배도권;정충일
    • 한국동물위생학회지
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    • 제20권3호
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    • pp.261-279
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    • 1997
  • The study for a effect of monitoring on bovine mastitis was conduced for improvement of raw milk from Jan. to Dec. in 1996. Sampling the milk of 367 cows(1, 406 quarters) from 5 herds in Inchon and were carried out California mastitis test(CMT), somatic cell count(SCC), isolation of pathogens and antibiotic sensitivity tests. The results were summarized as follows, 1. The number of bovine mastitis was 177 cows(48.2%) and 371 quarters(26.4%) : clinical mastitis : 25 cows(6.8%), 32 quarters(2.3%) and subclinicsl mastitis : 152 cows(41.4% ), 339 quarters(24.1%). Incidence rate of mastitis by season were Summer 52.0%, Fall and Winter 48% and Spring 41%. Incidence rate of mastitis by quarters were Summer 30%, Fall 28%, Winter 25% and Spring 21%, respectively. 2. In the distribution of CMT degree by quarter, CMT positive(CMT$\pm$) of 1, 406 quarters milk were 50.1% (704 quarters). The ratio of CMT positivity by quarter were left front quarter 55.8%, right front quarter 48.9%, right hind quarter 48.6% and left hind quarter 47% The ratio of CMT positivity by season were Summer 54.1%, Fall 49.7%, Spring 48.5% and Winter 48% 3. The highest mean SCC by season among 5 herds was "A" herd. Mean SCC (cell/ml) of A herd were Summer 2, 032, 000cells/ml, Fall 1, 109, 000cells/ml, Winter 782, 000cells/ml and Spring 577, 000cells/ml. The lowest mean SCC by season among 5 herds was "E" herds. Mean SCC of E herd were Summer 1, 064, 000cells/ml, Spring 795, 000cells/m1, Fall 429, 000cells/ml and Winter 400, 000cells/ml. Mean SCC of the other herds by season were little difference. 4. The milk samples of "A" herd were collected from 10 cows. In 3 seasons, mean SCC of No. 2 and 3 cows were than 1, 000, 000cells/ml. In 1 season, mean SCC of No. 6, 7 and 8 cows were than 1, 000, 000cells/ml. The more than mean SCC 1, 000, 000cells/ml of cows by season were distributed Summer 4 cows, Winter 3 cows, Spring and Fall 1 cow respectively. The milk samples of "B" herd were collected from 14 cows. In 3 seasons, mean SCC of No. 1 cow was more than 1, 000, 000cells/ml. In 2 seasons, mean SCC of No. 5, 9 and 14 cows were more than 1, 000, 000cells/ml. In 1 season, No. 3, 6 and 7 cows were more than 1, 000, 000cells/ml. The more than mean SCC 1, 000, 000cells/ml of cows by season were distributed Fall and Winter 4 cows respectively, Summer 3 cows and Spring 1 cow. The milk samples of "C" herd were collected from 18 cows. In 2 seasons, mean SCC of No. 16 cow was more than 1, 000, 000cells/ml. In 1 season, mean SCC of No. 1, 2, 6, 7, 13, 15 and 18 cows were more than 1, 000, 000cells/ml respectively. The more than mean SCC 1, 000, 000cells/ml of cows by season were distributed Summer 5 cows, Fall 3 cows, Spring 2 cows and Winter 1 COW. The milk sampes of "D" herd were collected 24 cows. In 3 season, mean SCC of No. 14 cow was more than 1, 000, 000cells/ml. In 2 seasons, mean SCC of No. 14 and 18 cows were more than 1, 000, 000cells/ml. In 1 season, mean SCC of No. 1, 2, 3, 8, 12, 17, 19, 20 and 21 cows were more than 1, 000, 000cells/ml. The more than mean SCC 1, 000, 000cells/ml of cows were distributed Fall 15 cows, Spring and Winter 4 cows respectively and Summer 3 cows. The milk samples of "E" herd were collected from 27 cows. In 2 seasons, mean SCC of No. 6, 7 and 21 cows were more than 1, 000, 000cells/ml. In 1 season, mean SCC of No. 2, 4, 7, 11, 14, 16 and 23 cows were more than 1, 000, 000cells/ml. The more than mean SCC 1, 000, 000cells/ml of cows were distributed Spring and Fall 5 cows respectively, Summer and Winter 2 cows, respectively. 5. The rate of isolated pathogenic microorganisms from bovine mastitis were summarized as follows : Staphylococcus sp 168 strains(45.8%), Streptococcus sp 82 strains(22.3%), Gram(-) sp 45 strains(12.3%), Gram(+) sp 51 strains and the other sp 21 strains(5.7%). 6. The highest of antibiotic sensitivity test of each microorganism was summarized as follows : Staphyolcoccus sp - cephalosporin 76%, gentamicin 55%, Streptococcus sp - ampicillin 61%, cephalosporin 63%, Gram(-) sp - gentamicin 58%, Gram(+) sp - cephalosporin 63%, The other sp - cephalosporin 90%. Microorganisms showed the highest sensitivity(68%) to cephalospsorin. Microorganisms showed the highest sensitivity(68%) to cephalospsorin.

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Screening of Preventive Effects of Herbal Prescriptions in Rat Model of Arterial Thrombosis Induced by Ferric Chloride

  • Lee, Ki Mo;Bang, Jihye;Lee, In Sun;Heo, Eun Jung;Kim, Bu Yeo;Kang, Hyung Won;Lyu, Yeoung Su;Jeon, Won Kyung
    • 대한한의학회지
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    • 제34권2호
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    • pp.20-28
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    • 2013
  • Objectives: This study examined the effects of 8 types of herbal prescriptions prescribed to alleviate dementia symptoms in a rat model of arterial thrombosis induced by ferric chloride ($FeCl_3$). Methods: Thirty minutes before 35% $FeCl_3$ treatment, SD rats were intraperitoneally injected with the 8 types of herbal prescriptions, respectively. We tested the effects of the herbal prescriptions on time to occlusion (TTO) in an arterial thrombosis model using a laser Doppler flow meter. In addition, thrombus weight (TW) and collagen fiber damages were evaluated in the same condition. Results: Herbal prescriptions showed the following rank-order based on their TTO: Chong-myung-tang (CMT) > modified Jangwonhan 02 (LMK02) > Toki-shakuyaku-san (TSS) ${\geq}$ Oren-gedoku-to (OGT) ${\geq}$ Yokukansan (YKS). In particular, CMT (100 mg/kg, i.p.) and LMK02 (100 mg/kg, i.p.) delayed the TTO the most ($14.83{\pm}0.98$ and $13.67{\pm}1.03$ min, respectively) compared with the vehicle group ($7.95{\pm}0.78$ min, P<0.001). In addition, CMT, LMK02, and OGT treatment ($0.63{\pm}0.01$, $0.66{\pm}0.02$ and $0.67{\pm}0.01$ mg/mm, respectively) significantly reduced thrombus weight compared with the vehicle treatment ($0.78{\pm}0.03$, P<0.001) and also alleviated collagen fiber damage (CMT; $28.40{\pm}2.22$%, LMK02; $30.79 {\pm} 4.07$%, OGT; $26.20{\pm}1.48$%) in the vessels injured by $FeCl_3$. Therefore, CMT and LMK02 showed the greatest preventive activity in rat model of arterial thrombosis induced by $FeCl_3$. Conclusions: These results provide experimental evidence for traditional use of herbal prescriptions, suggesting that CMT and LMK02 extracts could be used to prevent vascular injury and thrombosis in the early stages of dementia.

A Systematic Review and Meta-Analysis of Randomized Controlled Trials on Chuna Manual Therapy for Cervicogenic Headache

  • Lee, Dong-Wha;Kim, Ju-Young;Hong, Min-Ho;Koo, Byung-Soo;Kim, Geun-Woo
    • 동의신경정신과학회지
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    • 제30권2호
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    • pp.89-105
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    • 2019
  • Objectives: We conducted this study to evaluate the efficacy of Chuna Manual Therapy (CMT) for treatment of cervicogenic headache (CeH) through systematic review and Meta-analysis of randomized controlled trials (RCTs) as a preceding research to further research the effective of Chuna Manual Therapy for patients who suffered from CeH. Methods: We conducted a systematic review and meta-analysis by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We searched the studies from MEDLINE, Elsevier-EMBASE, The Cochrane Library, CAJD, KISS, KMBase, Korean Traditional Knowledge Portal, NDSL, and OASIS. The studies selected only in randomized controlled trials. We selected the chosen studies by the selection and the exclusion criteria, and evaluated the quality of the selected studies using the Jadad score and the Cochran ROB tool. We used the Visual Analogue Scale score (VAS) and Clinical total Effective Rate (CER) for the results and analyzed the results of the included studies using RevMan 5.3 software provided by the Cochran library. Results: We included 20 RCTs, including 1,673 subjects, in the systematic review and meta-analysis. After the intervention, the CMT group showed better results than the pharmacotherapy group, the physiotherapy group, and the combined treatment group. The CMT group showed a good effect on the CER and the VAS but showed a significant heterogeneity compared to the pharmacotherapy group. Conclusions: The CMT as monotherapy might have benefits on Cervicogenic Headache patient. Further well-designed studies need to be conducted.

고강도 아연도금 강판의 아크 용접시 보호가스의 비율에 따른 스패터량에 대한 고찰 (Amount of Spatter in Arc Welding for High-Strength Galvanized Steel According to Shielding Gas Composition)

  • 정영철;조영태;정윤교
    • 한국기계가공학회지
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    • 제15권1호
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    • pp.110-115
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    • 2016
  • The need for high-strength galvanized steel has recently increased because of the increased number of car consumers who want improved efficiency and exterior quality. High-strength galvanized steel with high corrosion resistance improves the durability of products and exterior quality. Furthermore, the gilt of zinc does not come off during machining because of the fine adhesive property of zinc. When these are welded, zinc has a lower melting temperature than iron, so zinc is more quickly vaporized than iron. Vaporized zinc can stick to electrodes, which increases spatter in welding transportation. Created spatter can enter the molten pool and develop into inner defects or blowholes and pits. Scattered spatter sticks to the product, which leads to the secondary cost of spatter removal. Therefore, in this study, comparisons of amounts of spatter generated are conducted according to the composition of shielding gas in the MIG and CMT processes to find optimal welding parameters.

손목 터널 증후군에 대한 추나요법의 효과: 체계적 문헌 고찰 (Chuna Manual Therapy for Carpal Tunnel Syndrome: A Systematic Review)

  • 박선영;이상현;허인;황의형
    • 척추신경추나의학회지
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    • 제16권2호
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    • pp.9-19
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    • 2021
  • Objectives This systematic review aimed to provide evidence for the effectiveness and safety of Chuna manual therapy (CMT) for carpal tunnel syndrome (CTS). Methods We searched 12 electronic databases (PubMed, Ovid-MEDLINE, EMBASE, The Cochrane Library, CNKI, CiNii, ScienceON, KMbase, KISS, OASIS, KMTANK, and RISS) up to the end of October 2021. We only included randomized controlled trials (RCTs) investigating CMT for the treatment of CTS. The methodological quality of the included RCTs was evaluated using the Cochrane Risk of Bias Tool 1.0. Results Six RCTs were eligible for inclusion in our study. A meta-analysis of four studies demonstrated positive results for the use of CMT when used in conjunction with Korean medicine treatment compared to those for Western conservative treatment for CTS. Conjunction treatment significantly improved the total efficacy rate compared to conservative treatment alone (P=0.0007, n=4). Conclusions There is reliable evidence for the use of CMT in treating CTS based on a published meta-analysis. To measure only the effect of Chuna, an experimental group should be designed with Chuna alone to evaluate its effectiveness. However, it should be noted that the studies included in this systematic review were heterogeneous and of low quality, thus warranting further investigation using well-designed RCTs.