• The Korean Society of Law and Medicine
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• v.18 no.1
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• pp.265-295
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• 2017

Breast tissue is composed of skin, mammary gland(including lactiferous duct), subcutaneous fat layer. The anatomical position is on the anterior chest wall(the outside of the chest cavity) but not on the inside of the thorax. Therefore, when the internal organs in the thoracic cavity are defined and expressed as 'organs' and the internal organs of each are labeled for a long time, for the breast located outside the thoracic cavity, it is thought that there is considerable difficulty in defining and recognizing the breast tissue as organs. For this reason, it is necessary to discourage the controversy over whether or not the breast is contained in the chest(or intra-thoracic cavity). In order to completely exclude it, it is assumed that the "chest-abdomen" can be called the "intra-thoraxic or intra-abdominal." But it is difficult to change the terms in various laws and regulations, I think that it would be necessary to insert only the clue clause "Breasts are excluded" in the detailed criteria for grading. In order to include it, it is necessary to change the terms of the ordinance or to say that the breast is exceptionally included.

• Journal of Forest and Environmental Science
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• v.11 no.1
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• pp.81-101
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• 1995

Random amplified polymorphic DNA (RAPD) technology, a recent approach in molecular genetics, is much usable to select the elite trees and to maximize the genetic gain in forest tree breeding program, providing a clue to determine the genetic marker-trait correlation. This review intorduces research on bark thickness and breeding strategy in Pinus elliottii, Pinus caribaea and their hybrid by Queensland Forest Service and ForBio Research Pty Ltd, University of Queensland, which employ RAPD technology. Genetic linkage map of $F_1$ hybrids includes 186 RAPD markers and 16 linkage groups (1641 cM long in total) and 6 quantitative trait loci are located putatively for bark thickness. Following recent research results and experiences in pine breeding programs, the forseeable stages in the application and development are proposed for marker assisted selectin; stage 1-determination of species specific markers for genes controlling traits of commercial interest, and stage 2-determination of marker-allele association for specific allelic variants within pure species. As pines inherit their megagametophytes from the seed parent and zygotic embryos from both male and female parents, the determination of marker-trait correlation is possible even in embryo stage, eventually making ways for the early selection of elite individuals.

• Journal of Korean Medical classics
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• v.20 no.4
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• pp.151-169
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• 2007

The "Tai Su(太素)" which was published by Yang Shang Shan(楊上善) during the Tang(唐) dynasty does not follow complicating hand down procedures allowing it to be preserved in a relatively satisfactory state, and the book is evaluated as a major article in the study of the "Yellow Emperor's Internal Classic(黃帝內經)" in the modern age. The book of "Tai Su explanation of channel diseases(太素 經脈病解)" offers the detailed description of disease symptoms found in the book of "Miraculous Pivot channels(靈樞 經脈)", and Yang Shang Shan(楊上善) provided relatively complete explanations from the perspective of the wane and wax of shadow and sunshine powers(陰陽消長). The present writing was projected to acknowledge the relationship between the books of "Tai Su explanation of channel diseases(太素 經脈病解)" and "Miraculous Pivot channels(靈樞 經脈)" and substantially attempted to understand the original text of the "Tai Su(太素)" by adopting the perspectives of Yang Shang Shan(楊上善) in explaining the disease symptoms as he attempted in the book of "Miraculous Pivot channels(靈樞 經脈)". Total 50 disease symptoms were explained in the book of "Tai Su explanation of channel diseases(太素 經脈病解)", and 33 of them are common to the symptoms described in the book of "Miraculous Pivot channels(靈樞 經脈)" by taking up about 66% of the book. The monthly attachment(月別配屬) of three shadow and three sunshine power(三陰三陽), which is described in the book of "Tai Su explanation of channel diseases(太素 經脈病解)" provides an important clue in understanding the exterior and interior(表裏) relationship, and the crucial perspective lies on the mutual intensity change of shadow and sunshine powers. Therefore, the monthly attachment of three shadow and three sunshine power provided by the present article helps to understand the meaning of the three shadow and three sunshine power along with the time attachment(時間配屬) described in the other chapter of the "Yellow Emperor's Internal Classic(黃帝內經)". In the method of explaining pathogenesis, the explanation was made by understanding the perspective of mutual intensity change of shadow and sunshine powers, and exterior and interior relationship along with the channel Path(經脈流注) have been used simultaneously. In the comment of the main article, Yang Shang Shan(楊上善) stated the channels of hands and feet(手足經脈) as the scope of the three shadow and three sunshine power, but the symptoms and signs are mainly focused on the channels of feet as in the book of "Miraculous Pivot channels(靈樞 經脈)".

• Biomedical Science Letters
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• v.3 no.1
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• pp.11-20
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• 1997

A regulation of differentiation in human neuroblastoma cells remains poorly understood, although it is of great importance in the clinical therapy of neuroblastoma. This study was aimed to elucidate effects of DNA synthesis inhibitors on the differentiation of neuroblastoma cells on the basis of morphological, biochemical and molecular respects. Three DNA synthesis inhibitors, sodium butyrate, hydroxyurea, cytosine arabinoside were used to explore their effects on the cellular morphology, the expression of c-myc and the elevation of choline acetyltransferase activity. They led to the extension or neurite-like processes reflecting differentiation or IMR-32 cells. In addition, the treatment of three DNA synthesis inhibitors resulted in the remarkable increases in the expression of c-myc as well as the stimulation of choline acetyltransferase activity which is involved in the synthesis of acetylcholine in the differentiated cholinergic neurons. Taken together, these results indicate that DNA synthesis inhibitors play an important role in the induction of cellular differentiation in IMR-32 cells. Furthermore these DNA synthesis inhibitors seem to be future useful to give an important clue (for the treatment of neuroblastoma).

• Journal of the Mineralogical Society of Korea
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• v.31 no.2
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• pp.123-135
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• 2018

This study tried to find the clue to Seokrok province by comparing Seokrok used in painting culture properties with Seokrok ore from domestic occurrence and imported Seokrok ore. To this end, chemical and mineralogical characteristics of painting cultural properties were identified with portable X-ray Florescence (p-XRF), micro X-ray diffraction (micro XRD) and SEM/EDS Analysis. To obtain Pb isotopic ratio, the Pb contained in Seokrok has been analyzed with Thermal Ionization Mass Spectrometer. Atacamite (or botallackite) and small quantity of brochantite were identified from Seokrok in Dancheong, and malachite was also identified from Buddhist painting besides those two ingredients. Without distinction of type, most Seokrok used in painting cultural properties is atacamite composed of Cu and Cl. From Pb isotope analysis, it was found that Seokrok in painting cultural properties was closer to that of north Korea, north China and Japan than south Korea as in regional division for East North Asia suggested by Mabuchi. The Pb isotopic ratio of domestic green mineral belongs to the distribution of Seokrok inside the painting cultural properties but imported malachite showed considerably difference. Considering the fact that atacamite, the main mineral of Seokrok in painting cultural properties is rarely produced from southern mine of the Korean Peninsula and the result of Pb isotope analysis.

• Journal of Korean Society of Forest Science
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• v.82 no.3
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• pp.246-253
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• 1993

The composition of the nitrogen forms of the organic layer and mineral soil horizons of 8 differing soil type was measured to find a clue to elucidate the problem on the fertility and nitrogen availabilities of forest soils. The ratio of inorganic $N(NH_4-N+NO_3-N)$ to total N was very low in every 0 layer and its maximum was only about 2%. And the inorganic N concentration of every mineral soil horizon was low, and the maximum of its rate to N was 3.7% in surface horizon and about 4.1% in lower horizon. Organic N form of O layer were characterized by the decrease of aminoacid-N, and the increased of hexosamine-N and amide-N according to the advance of decomposing process. The ranges of hydrolyzable-N of every flesh litter, F and H layer of the selected soils were about 80-90% and they- were hardly affected by the differences of tree species and decomposing process. The organic N form of every litter was similar and it was follows : aminoacid-N was not abundant and it ranges were about 40-50%, more than half of hydrolyzable-N. The hexosamine-N was eery poor and it ranged to only 2-7%. The amide-N teas low and about 10-23%. No distinguished difference was seen between the organic N forms of the O layer and surface horizon of dry and wet soils in brown forest soils.

• Journal of KIISE:Software and Applications
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• v.27 no.7
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• pp.769-783
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• 2000

In this paper, in order to disambiguate Korean noun word sense, we define a local context and explain how to extract it from a raw corpus. Following the intuition that two different nouns are likely to have similar meanings if they occur in the same local context, we use, as a clue, the word that occurs in the same local context where the target noun occurs. This method increases the usability of extracted knowledge and makes it possible to disambiguate the sense of infrequent words. And we can overcome the data sparseness problem by extending the verbs in a local context. The sense of a target noun is decided by the maximum similarity to the clues learned previously. The similarity between two words is computed by their concept distance in the sense hierarchy borrowed from WordNet. By reducing the multiplicity of clues gradually in the process of computing maximum similarity, we can speed up for next time calculation. When a target noun has more than two local contexts, we assign a weight according to the type of each local context to implement the differences according to the strength of semantic restriction of local contexts. As another knowledge source, we get a co-occurrence information from dictionary definitions and example sentences about the target noun. This is used to support local contexts and helps to select the most appropriate sense of the target noun. Through experiments using the proposed method, we discovered that the applicability of local contexts is very high and the co-occurrence information can supplement the local context for the precision. In spite of the high multiplicity of the target nouns used in our experiments, we can achieve higher performance (89.8%) than the supervised methods which use a sense-tagged corpus.

• Journal of Digital Convergence
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• v.18 no.2
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• pp.483-487
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• 2020

In this study, the effects of suspension training according to the types of ground. Fourteen healthy male college students measured for the characteristics of core muscle activity in suspension training on two different types of grounds, normal flat and unstable ground using a gym ball. EMG (Electromyography) was exploited to measure the activity of the core muscles according to the types of the ground. Muscle activity of the abdominal muscles, external oblique muscles, internal oblique muscles, and lower lumbar standing muscles was measured. The variables in analyses were measured by the means of % MVC method to standardize the EMG signal according to the ground type for each core muscle. In order to verify the differences in core muscles according to the type of ground the paired t-tests were performed at the significance level of 0.05 (p<.05). As a result of measuring the activity of the core muscles according to the various types of grounds, the difference between muscle characteristics obtained in two different grounds did not appear to be statistically significant. However, the result is an important clue to reconsider the notion that the training effect on the unstable ground is generally superior to the effect on the stable ground in the core muscle training. The type of ground in the core muscle training has been found not to significantly affect the muscle activation according to the results of this study. Regardless of the type of exercise program, hence, the difference in muscle activation will not be insignificant even with the standardized program strengthening core muscles.

• Journal of Life Science
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• v.19 no.6
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• pp.809-817
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• 2009

The phenotypes associated with a gene function are often the best clue to its role in the plant. Transgenic plants ectopically expressing or suppressing a gene can provide useful information related to the gene function. In this study, we constructed three vectors - pFGL571, pFGL846 and pFGL847 - for the Agrobacterium-mediated ectopic expression of plant genes using pPZP211 and modified CaMV 35S, UBQ3 or UBQ10 promoters. The three vectors have several merits such as small size, high copy in bacteria, enough restriction enzyme sites in multi cloning sites and nucleotide sequence information. Analysis of transgenic plants containing GUS or sGFP reporter genes under the control of modified CaMV 35S, UBQ3 or UBQI0 promoter revealed that all of the three promoters showed high activities during most developmental stages after germination and in floral organs. Furthermore, we generated a RNAi module vector, pFGL727, to suppress plant gene expressions and confirmed that pFGL727 is useful for the suppression of a gene expression using rice transgenic plants. Taken together, our new vectors would be very useful for the ectopic expression or the suppression of plant genes.

• Pediatric Infection and Vaccine
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• v.9 no.2
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• pp.222-229
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• 2002

Human infection with the lung fluke Paragonimus westermani has become rare in Korea. Human paragonimiasis is caused by eating raw fresh-water crayfishes or crabs infected with larval metacercariae. Recently, we experienced three cases of pulmonary paragonimiasis in a family. They ate raw fresh-water crayfishes that lived in a stream in Wolchulmountain. All the parients had hypereosinophilia and pulmonary infiltrates with pleural effusion or hydropneumothorax, which did not improve on antibiotics. Ingestion of raw crayfishes was a clue for paragonimiasis. Positive results were shown both on intradermal skin test and ELISA for Paragonimus westermani specific IgG. After treatment with praziquantel, the patients showed an improvement. This is the first familial human paragonimiasis, reported from Wolchulmountain in Chonnam Province where there had been no previous cases of paragonimiasis.