• The KIPS Transactions:PartC
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• v.9C no.4
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• pp.473-480
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• 2002

Although many researches on IDS (Intrusion Detection System) have been performed, the most of them are limited to the algorithm of detection software. However, even an IDS with superior algorithm can not detect intrusion, if it loses packets which nay have a clue of intrusions. In this paper, we suggest an efficient wav to improve the performance of IDS by reducing packet losses occurred due to hardware limitation and abundant processing overhead introduced by massive detection software itself. The reduction in packet losses is achieved by dropping hacking-free packets. The result shows that this decrease of packet losses leads an IDS to improve the detection rate of real attack.

• KSBB Journal
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• v.25 no.1
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• pp.11-17
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• 2010

Here, we evaluated the effect of thrombin on the interleukin-6 production induced by tumor-necrosis-factor-$\alpha$ in endothelial cells. It is well known that tumor-necrosis-factor-$\alpha$ mediates inflammatory responses by activation of nuclear factor-kappa-B in endothelial cells. Here, we showed that lower concentration of thrombin decreased the production of interleukin-6 induced by tumor-necrosis-factor-$\alpha$ and this inhibitory effect of thrombin on interleukin-6 production was mediated by interacting with protease-activated-receptor-1. In addition, phosphoinositide-3-kinase was also involved the anti-inflammatory responses by lower concentration of thrombin in endothelial cells. These results suggested that lower concentration of thrombin mediated anti-inflammatory responses by interacting with protease-activated-receptor-1 on the cell membrane and phosphoinositide-3-kinase in the cell. These findings will provide the important evidence in the development of new medicine for the treatment of severe sepsis and inflammatory diseases and good clue for understanding unknown mechanisms by which thrombin showed the pro-inflammatory or anti-inflammatory activities in endothelial cells.

• Journal of the Korean Institute of Landscape Architecture
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• v.28 no.4
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• pp.75-90
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• 2000

This study suggests the methods of the assessment and creation of biotopes in small and medium sized cities, in Korea. For this purpose, Chonju city was selected to classify and asses the biotope types. Moreover, relevant legislations to conserve and enhance urban biotopes were examined. The results of this study are as follows: 1) There were two approaches to asses the potential of urban biotopes in medium-sized cities. One was the urban scale evaluation for urban green spaces and the other was the biotope scale evaluation for the classification and evaluation of biotopes. 2) The urban scale evaluation was developed through overlaping analysis of landuse and vegetation factors. This study also included the conception of watershed. In this conception, three watersheds in Chonju city were characterized. According to these characteristics, individual programs for conservation and enhancement of urban green space were suggested. 3) For the biotope scale evaluation, Selected site was inclusively mapped and field investigation actually was carried. There were total 9 types of bitopes. Especially landuse was appeared in various evaluation items were vegetation structure, area of green space, condition of vegetation and vegetation profile. Mt, Gonji and Dukjin park, Chonbuk national University and fields were evaluated highly I the potential. 4) The biotope programs were based on the results of assessment and physical characteristics of biotopes. The uniform and simple levels on vegetation must be modified with various levels of vegetation structure and vernacular plants. And the physical characteristics like Points, Corridors and Patches can be organized by the conception of biotope networking theory. 5) The proper legislative environment was the clue elements for the biotope programs. Until now, only five types of parks and two types of green space are defined and the minimum size of green space has been proposed by the law. So, it is necessary to enlarge the conception of green space in legislation and improve the quality of green space by amending the related regulations. This study has limitation because it was selected only in Chonju. Through the continuous studies, we need to apply this other small and medium sized cities, South Korea. Also the data collection and management of theme maps such as actual vegetation, landuse and a soil must be done preliminary.

• The Journal of the Korea Contents Association
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• v.2 no.3
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• pp.1-15
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• 2002

A noel automated brain region extraction method in single channel MR images for visualization and analysis of a human brain is presented. The method generates a volume of brain masks by automatic thresholding using a dual curve fitting technique and by 3D morphological operations. The dual curve fitting can reduce an error in clue fitting to the histogram of MR images. The 3D morphological operations, including erosion, labeling of connected-components, max-feature operation, and dilation, are applied to the cubic volume of masks reconstructed from the thresholded Drain masks. This method can automatically extract a brain region in any displayed type of sequences, including extreme slices, of SPGR, T1-, T2-, and PD-weighted MR image data sets which are not required to contain the entire brain. In the experiments, the algorithm was applied to 20 sets of MR images and showed over 0.97 of similarity index in comparison with manual drawing.

• Journal of Microbiology and Biotechnology
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• v.20 no.3
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• pp.574-578
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• 2010

Archaebacteria Sulfolobus acidocaldarius contains the highly thermophilic cytochrome P450 enzyme (CYP119). CYP119 possesses stable enzymatic activity at up to $85^{\circ}C$. However, this enzyme is still considered as an orphan P450 without known physiological function with endogenous or xenobiotic substrates. We characterized the regioselectivity of lauric acid by CYP119 using the auxiliary redox partner proteins putidaredoxin (Pd) and putidaredoxin reductase (PdR). Purified CYP119 protein showed a tight binding affinity to lauric acid ($K_d=1.1{\pm}0.1{\mu}M$) and dominantly hydroxylated (${\omega}-1$) position of lauric acid. We determined the steady-state kinetic parameters; $k_{cat}$ was 10.8 $min^{-1}$ and $K_m$, was 12 ${\mu}M$. The increased ratio to $\omega$-hydroxylated production of lauric acid catalyzed by CYP119 was observed with increase in the reaction temperature. These studies suggested that the regioselectivity of CYP119 provide the critical clue for the physiological enzyme function in this thermophilic archaebacteria. In addition, regioselectivity control of CYP119 without altering its thermostability can lead to the development of novel CYP119-based catalysts through protein engineering.

• The Journal of the Korea Contents Association
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• v.8 no.5
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• pp.9-18
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• 2008

Web-services have originally been devised to share information as open services. In connection with it, hacking incidents have surged. Currently, Web-log analysis plays a crucial clue role in detecting Web-hacking. A growing number of cases are really related to perceiving and improving the weakness of Web-services based on Web-log analysis. Such as this, Web-log analysis plays a central role in finding out problems that Web has. Hence, Our research thesis suggests Web-DoS-hacking detective technique In the process of detecting such problems through SOM algorithm, the emergence frequency of BMU(Best Matching Unit) was studied, assuming the unit with the highest emergence frequency, as abnormal, and the problem- detection technique was recommended through the comparison of what's called BMU as input data.

• The Korean Journal of Applied Statistics
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• v.21 no.6
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• pp.1077-1091
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• 2008

In this study, we consider to assess the information ability of individuals related to local information. Questionnaire surveys are frequently used for studies on the measuring of information index and such specified indexes of society development. However, if questionnaire papers measured individuals' abilities and such parts of quality, the subjective judgments of respondents cannot but be intervened. Therefore a method which will enable subjective points to be comparatively objectified is needed. In this study, when an attempt is being made to measure individuals' information capacity through questionnaire surveys as the process for calculating the standards of regional information levels. Cases have been looked at for times when, by using a scorecard, individuals' subjective survey result have been be changed to be comparatively objectified scores and such process. The logit model was used in the preparation of the scorecard. In this study, we have presented a clue which enables the comparative measurement about regional information gaps by using characteristics of regional population statistics.

• Journal of Korean Society of Transportation
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• v.27 no.6
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• pp.69-77
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• 2009

The maximum and mean acceleration rates of vehicles estimated from the stopping conditions at signalized intersections provided an important clue to analyze traffic accident investigation when there was a dispute about legal liability such as first entering vehicle at the intersection, etc. This paper provided the maximum and mean acceleration rates of vehicles reflecting current traffic conditions in Korea through field studies. The mean acceleration rates of vehicles at stopline were measured up to 50m at the intervals of 5m. Results showed that the mean acceleration rate for bus was found to be $1.011^m/s^2{\sim}1.314^m/s^2$(0.1g~0.13g), and for passenger car was $1.548^m/s^2{\sim}1.818^m/s^2$(0.16g~0.19g). Statistical test results indicated that the observed differences from vehicle types and vehicle positions were statistically significant for the all ranges tested. It is expected that the accuracy of accident investigation practice will be improved by applying the acceleration rate values presented in this paper.

• Journal of Soil and Groundwater Environment
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• v.20 no.3
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• pp.34-40
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• 2015

Studies using stable water vapor isotopes have been recently conducted over the past two decades because of difficulties in analysis and sample collection in the past. Stable water vapor isotope data provide information of the moisture transport from ocean to continent, which are also used to validate an isotope enabled general circulation model for paleoclimate reconstructions. The isotopic compositions of groundwater and water vapor also provide a clue to how moisture moves from soil to atmosphere by evapotranspiration. International Atomic Energy Agency designates the stations over the world to observe the water vapor isotopes. To analyze the water vapor isotopes, a cryogenic sampling method has been used over the past two decades. Recently, two types of laser-based spectroscopy have been developed and remotely sensed data from satellites have the global coverage. In this review, measurements of isotopic compositions of water vapor will be introduced and some studies using the water vapor isotopes will also be introduced. Finally, we will suggest the future study in Korea.

• Applied Chemistry for Engineering
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• v.23 no.5
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• pp.496-500
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• 2012

Arthrospira platensis (A. platensis) is an economically important filamentous microalgae. The isolation of mutants by chemical or physical mutagen is a clue for the strain improvement. In this study, effects of ultraviolet-B (UV-B) radiation on A. platensis were investigated. Cells (or microalgae) were exposed to UV-B (15 Watt, 254 nm) for 1, 3, 5, and 10 min, and resulting mutants were designated UM1, UM3, UM5, and UM10, respectively. Especially, the lipid content of UM5 mutant was considerably increased by 8~11 fold compared to that of wild types. Moreover, the carotenoid content and antioxidant enzyme (peroxidase and superoxide dismutase) activity were increased. It was shown that UV-induced mutants can accumulate bioactive compounds, which will be useful for the industrial production of valuable products.