• Journal of Korea Game Society
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• v.6 no.3
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• pp.43-50
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• 2006

This study is to develop a learning program supporting how to teach multi-level of students in number and operating field in the elementary school. Mathematics requires different teaching ways for various standards of student in the school. However, in most of elementary school teachers are having hard time giving the proper lesson for each student due to the lack of supplementary classes and the excessive numbers of students in a class. Thus this research provides "Game-type learning Program" and supports individual learning lessons to give each student an opportunity to form a correct concept of number and operation. This system sets up suitable steps for each student by checking their leaning progress and accomplishment. When a student has a trouble, can give a help or show specific things which could be related with the matter. As a result, students have got more interests in studying math, furthermore, actually, the help and giving a clue helped students a lot in settling the problems.

• The Bulletin of The Korean Astronomical Society
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• v.42 no.2
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• pp.50.2-50.2
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• 2017

Spatial distribution of atmosphereless bodies in the solar system provides an important clue as to their origins, namely asteroids from Mainbelt or comets from outer solar system. It is, however, difficult to distinguish asteroids and dormant comets due to their similar appearances. In this study, we conducted a unique observation to differentiate asteroids and dormant comets in terms of 'polarimetry'. We observed (331471) 1984 QY1 (hereafter QY1) at large phase angles using the Multi-Spectral Imager (MSI) on the 1.6-m Pirka Telescope from UT 2016 May 25 to June 24. QY1 is a dormant comet candidate in terms of the dynamical properties (i.e. the Tisserand parameter with respect to Jupiter, TJ = 2.68). We analyzed the polarization degree of QY1 as a function of phase angle and found its maximum polarization degree, $Pmax=8.68{\pm}0.28%$ and $8.72{\pm}0.38%$, in RC-and V-band, respectively, around the phase angle of ${\alpha}=100^{\circ}$. In addition, we obtained the geometric albedo, $pV=0.16{\pm}0.02$ by means of an empirical slope-albedo law. The polarimetric properties and the albedo value we acquired are similar to those of S-type asteroids rather than cometary nuclei. In this presentation, we introduce our observation and findings. In addition, we further discuss a dynamical transportation process from Mainbelt to the current orbit.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.48 no.2
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• pp.244-248
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• 2015

We explored the efficiency of natural antibacterial agents used to enhance the self-life and sensory properties of shucked and packed Pacific oyster Crassostrea gigas, which are in high demanded. First, we screened natural resources exhibiting antibacterial activity against food spoilage and pathogenic bacteria. Of theses, ignited oyster shell powder (IOS) and the natural food preservative, lactic acid bacteria fermented powder (LBF), were selected for further study considering the efficacy, mass production, and cost. The addition of 0.1% IOS (W/V) and 0.5% LBF (W/V) to shucked and packed oyster optimally extended the shelf-life without affecting the sensory evaluation. The results obtained in this study will provide a clue to enhance self-life in raw oyster products.

• Korean Journal of Biological Psychiatry
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• v.11 no.2
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• pp.155-164
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• 2004

Objective:The present study examined the association between basic neurocognitive functions and emotional recognition in chronic schizophrenia. Furthermore, to Investigate cognitive variable related to emotion recognition in Schizophrenia. Methods:Forty eight patients from the Yongin Psychiatric Rehabilitation Center were evaluated for neurocognitive function, and Emotional Recognition Test which has four subscales finding emotional clue, discriminating emotions, understanding emotional context and emotional capacity. Measures of neurocognitive functioning were selected based on hypothesized relationships to perception of emotion. These measures included:1) Letter Number Sequencing Test, a measure of working memory;2) Word Fluency and Block Design, a measure of executive function;3) Hopkins Verbal Learning Test-Korean version, a measure of verbal memory;4) Digit Span, a measure of immediate memory;5) Span of Apprehension Task, a measure of early visual processing, visual scanning;6) Continuous Performance Test, a measure of sustained attention functioning. Correlation analyses between specific neurocognitive measures and emotional recognition test were made. To examine the degree to which neurocognitive performance predicting emotional recognition, hierarchical regression analyses were also made. Results:Working memory, and verbal memory were closely related with emotional discrimination. Working memory, Span of Apprehension and Digit Span were closely related with contextual recognition. Among cognitive measures, Span of Apprehension, Working memory, Digit Span were most important variables in predicting emotional capacity. Conclusion:These results are relevant considering that emotional information processing depends, in part, on the abilities to scan the context and to use immediate working memory. These results indicated that mul- tifaceted cognitive training program added with Emotional Recognition Task(Cognitive Behavioral Rehabilitation Therapy added with Emotional Management Program) are promising.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.2
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• pp.301-307
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• 2009

In korean society, the chronic life style diseases are increasing. It is caused by the approach of the aged society and the highly increasing income. Accordingly the preventive side of the health promotion and management is very important. In the oriental medicine, the general disease pre-estimate and the management program are necessary. On this point, the sign forecast is very significant in connection with the disease pre-estimate in the preventive disease management side. The sign forecast according to the human shape type diagnosis is mainly the sign of the super-early stage, The difference of the shape type has the difference of the special affinity about the disease. Accordingly we can find the sign forecast from the latent disease in the early stage. In NAE-GYEONG(內經), the theory of "five body form's type" can be pre-estimated the latent tendency and the clue of the disease and the growing tendency of disease in relation to the Differentiation of Syndrome, In the disease pre-estimate side, the graspe and management of the sign forecast from the latent disease will be the part of the new development.

• Molecular & Cellular Toxicology
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• v.1 no.2
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• pp.73-77
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• 2005

Nickel is the one of potent environmental, the occupational pollutants and the classified human carcinogens. It is a serious hazard to human health, when the metal exposure. To prevent human diseases from the heavy metals, it is seemingly important that understanding of how nickel exerts their toxicity and carcinogenic effect at a molecular and a genomic level. The process of nickel absorption has been demonstrated as phagocytosis, iron channel and diffusion. Uptaked nickel has been suggested to induce carcinogenesis via two pathways, a direct DNA damaging pathway and an indirect DNA damaging pathway. The former was originated from the ability of metal to generate Reactive Oxygen Species (ROS) and the reactive intermediates to interact with DNA directly. Ni-generated ROS or Nickel itself, interacts with DNAs and histones to cause DNA damage and chromosomal abnormality. The latter was originated from an indirect DNA damage via inhibition of DNA repair, or condensation and methylation of DNA. Cells have ability to protect from the genotoxic stresses by changing gene expression. Microarray analysis of the cells treated with nickel or nickel compounds, show the specific altered gene expression profile. For example, HIF-I (Hypoxia-Inducible Factor I) and p53 were well known as transcription factors, which are upregulated in response to stress and activated by both soluble and insoluble nickel compounds. The induction of these important transcription factors exert potent selective pressure and leading to cell transformation. Genes of metallothionein and family of heat shock proteins which have been known to play role in protection and damage control, were also induced by nickel treatment. These gene expressions may give us a clue to understand of the carcinogenesis mechanism of nickel. Further discussions on molecular and genomic, are need in order to understand the specific mechanism of nickel toxicity and carcinogenicity.

• Journal of Life Science
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• v.18 no.11
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• pp.1600-1605
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• 2008

This study was performed to verify the gene expression of 3T3-L1 using the siRNA of the aromatase gene, which is the estrogen synthesis enzymes. First of all three pairs of siRNA were designed from the CYP19A1 (aromatase) and analyzed the formation of fat cell mechanism by transferring gene to 3T3-L1 and differentiating it. As a result, the expression of leptin gene, which is the main gene causing the obesity, was controlled and the cause of the obesity is related with the insulin specifically. The overexpression of adiponectin and adipsin was observed. This result showed that the formation of the fat was controlled a little without any side effect by obstructing a specific material out of all the signal systems in the fat formation. This study will be an important clue to make it clear that the lack or overexpression of estrogen might be the cause of fat formation mechanism.

• Journal of the Korea Safety Management & Science
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• v.11 no.2
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• pp.19-26
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• 2009

This study was designed to analyse the performance and the mechanisms of workers' participation and communications in industrial accident prevention activities leading to the reduction of industrial accidents. This study also aimed to find out the causal relationship influencing the promotion of prevention activities of industrial accidents. Of the manufacturing businesses with more than 5 workers as the population of the survey, a questionnaire was conducted with 2,500 workspaces chosen by stratified sampling. Out of 2500 workspaces, 971 workspaces equipped with industrial safety and health committee were analysed in this study. According to the results of this study, the primary influential factors on safety activities were the management of industrial accidents and the cooperations between supervisors and workers on site. The secondary influential factor was the establishment of industrial safety and health committee. Regarding the effectiveness of industrial accident reduction, -0.01 was shown by workplace safety activities by themselves and -0.09 was shown by participation and communications through indirect safety activities. This indicated workers' participation and communications play an important role in the reduction of industrial accidents. By discovering the clue to the mechanism of the workers' participation and communications, this study is expected to stimulate the reduction of industrial accidents by emphasizing the importance of workers' participation and communications in resolving the safety and health problem in the workplaces.

• Journal of Sasang Constitutional Medicine
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• v.29 no.1
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• pp.59-71
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• 2017

Objectives It is important to decide if the patient is belong to cold syndrome or heat syndrome in Sasang Constitutional Medicine. The purpose of this study is to report some proof to determine cold and heat syndrome and characteristic of the patient who can be treated with Cheongsimyeonja-tang. Methods To evaluate the results of this treatment, muscular symptom was assessed by Visual Analogue Scale(VAS). The patient's general condition such as urinary and fecal discomfort is assessed by the progress notes. Results The patient did not improved when she was treated with Choweseuncheung-tang. But when she was treated with Cheongsimyeonja-tang, she got improved with not only her main problem such as muscular symptom, but also general condition such as indigestion, urinary & fecal discomfort and menopausal symptom. Conclusion This study suggests that number of defecation per day also can be the clue to decide heat or cold syndrome not only appearance of defecation. And the patients who can be treated by Cheongsimyeonja-tang is different from the patients who can be treated by Yeoldahansotang in the color of their face, personality and edema.

• Korean journal of applied entomology
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• v.11 no.1
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• pp.31-35
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• 1972

1. Continuous light induced more conidia than alternating light and darkness treatment in isolate Chinju 1. Isolate Suwon 3 produced much more conidia on synthetic medium than Chinju 1 in light. Conidial formation in Suwon 3 increased remarkably with alternate light and darkness in 8 days incubation. 2. Light was essential for perithecial formation in Chinju 1. No matured perithecia were observed in Suwon 3 with any treatment. Abundant perithecia were produced in Chinju 1 but only perithecial initiation occurred in Suwon 3. Suwon 3 produced significantly more conidia than Chinju 1, while perithecial formation was reversed. 3. Conidial numbers in soil decreased significantly through the winter at 10, 30 and 50 per cent soil moisture, with the most striking decrease at 10 per cent levels, but the number recovered again beginning in March, regardless of the soil moisture. The above results provide us a useful clue to support the possbility the conidia may serve as a primary inoculum.