• 식품과학과 산업
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• 제50권1호
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• pp.11-15
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• 2017

Epigenomics is a study that analyzes and quantifies various epigenetic alterations that affect gene expressions in cells from the viewpoint of collective characteristics on biological molecular pools. DNA methylation and histone modification in cells can induce the epigenetic alterations. Especially, epigenetic alterations influenced by external factors as ingested foods and other environmental factors have been examined in the whole genome regions, which provide accumulated data of altered regions or patterns of global genome, Statistical analyses of these regions or patterns enables us to correlate epigenomic changes with human diseases in the whole genome region. Finding meaningful regulators is a major concern of epigenomic research in recent years, and these results will give the food industry an important clue to future food

• 중국학논총
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• 제71호
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• pp.131-149
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• 2021

The Oriental thought does not stay in self, society, or state, but goes further to expand its bounds as "Chunha(the World, 天下)", which is not just the spacious expansion but the moral expansion. It provides a clue to overcome the limitations of the Western international political thought resulting in nationalistic tendencies. Such a cosmopolitcan orientation in the East can be found in the concepts of "Wangdo(Just Way, 王道)", "Yinjung(Benevolent politics, 仁政)", which make Hua(harmony, 和) its essential characteristics. If the East Asian community is formed, it should be based on universal principles that all East Asian citizens can sympathize with from below, not in a one-sided and coercive way. In this regard, the formation of "Sahaeyilga(四海一家, We are the world)", the "Chunha天下" based on the philosophy of the peace seeking 'similarity' in 'difference', can provide philosophical clues to resolve the conflicts and contradictions of the current isolationalist and confrontational international situation.

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2003년도 하계학술연구발표회 및 한.일 공동심포지엄
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• pp.40-40
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• 2003

Finding a solid material with a large value of the magnetocaloric effect near room temperature is of exceeding importance, since this would lead to the development of more compact and environmentally safer cooling systems. Recently, manganites become the focus of attention due to its large magnetocaloric effect. We demonstrate, via dynamic calorimetric measurements, that the large magnetocaloric effect in perovskite manganites stems from the first-order nature of the magnetic transition. Our results offer a clue in search for ideal magnetocaloric materials working in the vicinity of room temperature.

• 대한유전성대사질환학회지
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• 제22권2호
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• pp.37-45
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• 2022

Inherited metabolic disorders (IMD) are a large group of rare disorders affecting normal biochemical pathways. The ophthalmic involvement can be very varied affecting any part of the eye, including abnormalities of cornea, lens dislocation and cataracts, retina and the optic nerve, and extraocular muscles. Eye disorders can be initial symptoms of some IMD and can be clue for diagnosis of IMD. However, eye disorders can evolve later in the natural history of an already diagnosed metabolic disorder. Awareness of IMDs is important to facilitate early diagnosis and in some cases instigate early treatment if a patient presents with eye involvement suggestive of a metabolic disorder. Ophthalmological interventions are also an important component of the multisystem holistic approach to treating patients with metabolic disorders.

• International Journal of Advanced Culture Technology
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• 제11권1호
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• pp.153-158
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• 2023

Experts are concerned about the lack of troops and security vacuum due to the low birth rate in the Republic of Korea. They consider policies to expand the proportion and role of female soldiers to address these issues. In this regard, We would like to introduce the successful use of female personnel in the Ukrainian military and draw implications for the Korean military. This will provide a clue to offset the shortage of troops in the Republic of Korea.

• 한국정밀공학회지
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• 제14권12호
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• pp.30-47
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• 1997

This paper encompasses a general technology in robot deburring automation using solid rotaing burr tools. Deburring is a cumbersome area in finishing technology, where design concept and system implementation is based on knowhows and experiences rather then theoretical development. In the field engineering it is diffcult to find a clue to where and how to start the system design. This paper presents a guide inselection of tool concept of geometry and material. Also, the concept of tool compliance system is introduced, which is one of the most important factor in robot deburring. Typical problems encountered in the field are classified into 20 categories and the solutions are suggested by the proven technology from the expertise. Special problems in polymer and diecasting areas are also briefly mentioned.

• 천문학회보
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• 제45권1호
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• pp.44.3-44.3
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• 2020

Sunspot substructure is an important subject to explain their stability and energy transport. Previous studies suggested two substructure models, monolithic and spaghetti model, but no clear evidence has been found supporting a particular model. To obtain the clue of the sunspot substructure the IRIS Mg II 2796Å slit-jaw images (SJI) were examined. The Mg II images formed in the chromosphere show bright patches inside umbrae which are regarded as an observational signature of upward propagating slow magnetohydrodynamic (MHD) waves. The slow MHD waves are expected to be generated by convective motion below the photosphere. By tracking the motion of the bright patches it is possible to estimate the locations of oscillation centers that correspond to the occurrence position of the convections. I investigated the spatial distribution of the oscillation center in a merging sunspot and found it is randomly distributed. It implies that the occurrence rate of the convective motion inside the sunspot is not much different from that of between the two sunspots, and supports the spaghetti model as the sunspot substructure.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2023년도 봄 학술논문 발표대회
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• pp.21-22
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• 2023

In reinforced concrete constructions, reinforcing bar generates more CO₂ per unit weight than other construction materials. In particular, cutting and bending rebar is the main source of rebar waste in the construction industry. Rebar-cutting waste is inevitable during the construction of a reinforced concrete structure since the rebar is not manufactured as designed. Large amounts of waste can be avoided by utilizing optimal cutting patterns and schedules. This research provides a fundamental analysis of the automatic calculation of column rebar length using BIM-based shape codes to minimize cutting waste to near zero. By employing this approach in practice, it is possible to minimize the rate of rebar-cutting waste, reduce costs, shorten construction duration, and reduce CO₂ emissions. In addition, the development of this research will serve as a clue for the development of BIM-based rebar layout automation algorithms.

• 천문학회보
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• 제46권1호
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• pp.29.3-29.3
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• 2021

Globular clusters (GCs) form at the very early stage of galaxy formation, and thus can be used as an important clue indicating the environment of the galaxy formation era. Although various GC formation scenarios have been suggested, they have not been examined in the cosmological context. Here we introduce the 'particle tagging method' in order to investigate the formation scenarios of GCs in a galaxy cluster. This method is able to trace the evolution of GCs that form in the dark matter halos which undergo the hierarchical merging events in galaxy cluster environments with an effective computational time. For this we use dark matter merger trees from the cosmological N-body simulation. Finally, we would like to find out the best GC formation scenario which can explain the observational properties of GCs in galaxy clusters.

• BMB Reports
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• 제57권5호
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• pp.216-231
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• 2024

Mammalian genomes are intricately compacted to form sophisticated 3-dimensional structures within the tiny nucleus, so called 3D genome folding. Despite their shapes reminiscent of an entangled yarn, the rapid development of molecular and next-generation sequencing technologies (NGS) has revealed that mammalian genomes are highly organized in a hierarchical order that delicately affects transcription activities. An increasing amount of evidence suggests that 3D genome folding is implicated in diseases, giving us a clue on how to identify novel therapeutic approaches. In this review, we will study what 3D genome folding means in epigenetics, what types of 3D genome structures there are, how they are formed, and how the technologies have developed to explore them. We will also discuss the pathological implications of 3D genome folding. Finally, we will discuss how to leverage 3D genome folding and engineering for future studies.