• Proceedings of the Korean Institute of Building Construction Conference
• /
• 2022.04a
• /
• pp.85-86
• /
• 2022

Traditionally, the facility inspection was visually conducted by the managers, and consequently the result can be subjective because of different perspective and experience of them. To solve this problem, the studies on this topic has tried to integrate the UAS. However, it is still concerned to use in practice due to the lack of analysis of the performance factors affecting the UAS-based facility condition inspection. Hence, the purpose of this study is to identify the critical factors as well as their correlations by modeling causal loop diagram (CLD). A total of 20 variables were derived in four categorized groups, and the relationships were analyzed. Further study will develop a system dynamics (SD) model to simulate various scenarios based on stock-flow diagram through the defined relationships in this study.

• Radiation Oncology Journal
• /
• v.28 no.1
• /
• pp.23-31
• /
• 2010

Purpose: To evaluate the relationship between the normal tissue complication probability (NTCP) of 3-dimensional (3-D) radiotherapy and the radiographic parameters of 2-dimensional (2-D) radiotherapy such as central lung distance (CLD) and maximal heart distance (MHD). Materials and Methods: We analyzed 110 patients who were treated with postoperative radiotherapy for breast cancer. A two-field tangential technique, a three-field technique, and the reverse hockey stick method were used. The radiation dose administered to whole breast or the chest wall was 50.4 Gy, whereas a 45 Gy was administered to the supraclavicular field. The NTCPs of the heart and lung were calculated by the modified Lyman model and the relative seriality model. Results: For all patients, the NTCPs of radiation-induced pneumonitis and cardiac mortality were 0.5% and 0.7%, respectively. The NTCP of radiation-induced pneumonitis was higher in patients treated with the reverse hockey stick method than in those treated by other two techniques (0.0%, 0.0%, 3.1%, p<0.001). The NTCP of radiation-induced pneumonitis increased with CLD. The NTCP of cardiac mortality increased with MHD ($R^2=0.808$). Conclusion: We found a close correlation between the NTCP of 3-D radiotherapy and 2-D radiographic parameters. Our results are useful to reanalyze the previous 2-D based clinical reports about breast radiation therapy complications as a viewpoint of NTCP.

• Genomics & Informatics
• /
• v.6 no.4
• /
• pp.181-191
• /
• 2008

RAS guanyl-releasing protein 3 (RasGRP3), a member of the Ras subfamily of GTPases, functions as a guanosine triphosphate (GTP)/guanosine diphosphate (GDP)-regulated switch that cycles between inactive GDP- and active GTP-bound states during signal transduction. Various growth factors enhance hepatocellular carcinoma (HCC) proliferation via activation of the Ras/Raf-1/extracellular signal-regulated kinase (ERK) pathway, which depends on RasGRP3 activation. We investigated the relationship between polymorphisms in RasGRP3 and progression of hepatitis B virus (HBV)-infected HCC in a Korean population. Nineteen RasGRP3 SNPs were genotyped in 206 patients with chronic liver disease (CLD) and 86 patients with HCC. Our results revealed that the T allele of the rs7597095 SNP and the C allele of the rs7592762 SNP increased susceptibility to HCC (OR=1.55, p=0.04 and OR=1.81${\sim}$2.61, p=0.01${\sim}$0.03, respectively). Moreover, patients who possessed the haplotype (ht) 1 (A-T-C-G) or diplotype (dt) 1 (ht1/ht1) variations had increased susceptibility to HCC (OR=1.79${\sim}$2.78, p=0.01${\sim}$0.03). In addition, we identified an association between haplotype1 (ht1) and the age of HCC onset; the age of HCC onset are earlier in ht1 +/+ than ht1 +/- or ht1 -/- (HR=0.42${\sim}$0.66, p=0.006${\sim}$0.015). Thus, our data suggest that RasGRP3 SNPs are significantly associated with an increased risk of developing HCC.

• Journal of the Korean Society of Environmental Restoration Technology
• /
• v.20 no.4
• /
• pp.43-61
• /
• 2017

The wetlands are facing environmental changes such as desiccation that occurs with the passage of time and reduced ecosystem services from wetlands in the city. In order to maintain the ecosystem services provided by wetlands in urban areas, a system thinking about the trade-off phenomenon of ecosystem services occurring as the wetlands undergo environmental changes is needed. Therefore, the purpose of this study is to develop strategies for wetland design using system thinking approach to enhance the resilience of ecosystem services degraded by the desiccation of wetlands and other disturbances. The objectives of this study include the system boundary and variables. Second, analyzing the dynamics of wetland design strategy. Third, it analyzes the trade-off phenomenon of ecosystem services in terms of the hydrology, hydric soil, and plants strategies to mitigate these effects. Fourth, wetland basic design to improve the resilience of ecosystem services. A wetland in Abuk-Mountain Neighborhood Park, Miryang-si, Gyeongsangnam-do, has been selected as a case study. Causal loop diagrams(CLDs) are used to analyze feedback in the wetland regime. In summary, hydrology, hydric soil, and plants is suggested as system boundaries to design plan. Design strategies for the wetland focused on robustness, redundancy, rapidity, and resourcefulness as a result of CLD analysis are first proposed in order to effectively maintain the wetland regime over the long term. Secondly, in a section related to hydrology, the CLD results show the trade-offs between provisioning-cultural services and regulating services. In order to control these services, a "water cycling system" has been implemented due to its strength in terms of robustness. The CLDs for hydric soil showed the trade-offs between regulating services and supporting services. An "installation of storm drainage for maintaining water levels" was selected due to the strength offered in terms of redundancy and rapidity. The CLDs for plants showed the trade-offs between provisioning - cultural services and regulating services. In order to control the strategic points, the "planting of indigenous vegetation" was suggested given the strength in terms of redundancy. In this study, a wetland design method is proposed that can improve the resilience of wetland ecosystem services by analyzing the dynamics overtime. The results of this research can theoretically be applied to help restore ecosystem services in wetlands using ecological landscape design. In addition, this study will contribute to reducing maintenance costs by improving wetland resilience.

• Korean Journal of Construction Engineering and Management
• /
• v.24 no.5
• /
• pp.3-11
• /
• 2023

Building information modeling (BIM) can help to visualize and manage the building-related information at the object-based level, and it is possible to help link the tasks in the network of Hanok construction. While many studies have significant interest in using BIM for modern construction, there is only few studies to observe the use of BIM for traditional construction, commonly called Hanok construction in South Korea. Hence, the main goal of this study is to develop a system dynamic model for investigating how the BIM can be widely used for Hanok construction. To this end, this study identified the factors influencing the BIM uses for the Hanok construction, developed a causal loop diagram (CLD) to investigate the interrelationships among the factors, and provided a final model based on the mathematical definitions. Based on the scenario analysis, it is demonstrated that the support to building Hanok and education cost for BIM positively influence activating and using the BIM for the Hanok construction. Based on the dynamics of the factors identified in this study, it is important to consider expanding support for Hanok construction and education cost for BIM to successfully integrate and utilize BIM in the construction industry.

• Journal of the Economic Geographical Society of Korea
• /
• v.26 no.3
• /
• pp.169-189
• /
• 2023

The study aims to synthesize the discussion of the innovation district and suggest an alternative to the governance system of the innovation district. Cluster policies that focus on industrial specialization, networking, value chains, and industrial ecosystems have shown some problems and limits in advanced industrial economies. The innovation district, suitable for the era of urban innovation, convergence of industry, housing, leisure, and related variety, emphasizes cooperation through the convergence of various innovations, workshops and industries, and communities. It is important to build a quintuple helix based on cooperative governance through public-private partnerships, integrate the physical and cultural atmosphere, and service industries that strengthen the place prestige. Beyond the industrial aspect, innovation districts can facilitate changes in urban amenities and lifestyles and creative atmosphere, such as diversity, lifestyle, charms, and openness, and promote social vitality and economic interactions. The governance of innovative districts can promote inter-organizational exchanges, and combinations. When knowledge is created through exchanges between companies, it also affects changes in the governance system, evolving from a rigid and centralized system to an open, dynamic, and organic system. Through the innovation policy, the existing Central Business Districts (CBD) can be able to be transformed into a Central Lifestyle Districts (CLD).

• Korean System Dynamics Review
• /
• v.12 no.2
• /
• pp.95-126
• /
• 2011

This paper aims at developing a System Dynamics model with an augmented predator-prey interaction structure to deal with the population management of roe deer in Jeju, Korea. Although people still regard the creature as one of the important tourist attractions, there has been much debate on the issues of the appropriateness of the population size of roe deers because they have been stigmatized as crop damagers, and roadkill/poaching victims due to their natural habit to move around from the top mountain to the lowland of the island. The model is therefore to incorporate these migrating and grazing behaviors into an augmented Lotka-Volterra model coupling roe deer population in both parts of the island to that of predators and preys of the species. The authors also provide a comprehensive set of dynamic hypotheses and relevant CLD/SFD to understand the population dynamics of roe deer and co-evolving species and perform the steady-state analysis of the proposed equation system to verify the model behavior of the numerical example lastly presented in this paper.

• Information Systems Review
• /
• v.15 no.2
• /
• pp.21-40
• /
• 2013

Because of the recent development of information technology, especially the popularization of social media, false rumors and abusive comments on social media have increased, which has accelerated conflicts in online society. Since these conflicts lead to significant negative influences on online society, it is important to figure out how to cope with the conflicts and integrate the society. Thus, this study provides effective political implications that will advance the society where people can communicate based on trust in social media. In addition, we suggest new sociocultural change phenomenon and social integration by drawing the Causal Loop Diagram focusing on the dimension of social capital in social media environment.

• The Journal of Information Systems
• /
• v.24 no.2
• /
• pp.73-96
• /
• 2015

Purpose Information security industry is rapidly growing, but has been confronted with many challenges in a business environment. One of them is the imbalance between supply and demand of information security manpower, which has caused an insecure market situation. Therefore, this study has derived factors of promoting and hindering information security manpower from governance, academics, corporations, and workforce perspectives, and has analyzed a sequence of cause and effect of each factor. Design/methodology/approach This study is an exploratory research based on the interviews. The causal loop diagram (CLD) was developed to deduce key issues and propose alternatives. Findings The result of this study is expected to help the development of information security manpower in Korea, by minimizing the potential negative effects as well as maximizing the positive effects. This study found out the dynamic causes and effects of the security manpower system in each stakeholder's perspective. The cause-and-effect relationships between the stakeholders will be able to contribute to solve the imbalance of supply and demand in security manpower system.

• Clinical and Experimental Pediatrics
• /
• v.46 no.3
• /
• pp.308-311
• /
• 2003

Congenital chloride diarrhea is a serious autosomal recessive disease, and defect of intestinal electrolyte absorption that involves, specifically, $Cl^-/{HCO_3}^-$ exchange in the distal part of the ileum and colon. The clinical feature is dominated by profuse, watery diarrhea containing high concentrations of chloride(>90 mmol/L) and sodium. The chloride loss results in severe dehydration with a hypochloremic alkalosis. The molecular pathology involves an epithelial $Cl^-/{HCO_3}^-$ exchanger protein. Mucosal ion transport is affected to differing degrees and the severity of the disease may thus vary. Recently, a gene defect on chromosome 7 has been identified. However, there was a deficit in replacement of fluid and electrolyte, abdominal distension remained and the character of stools was watery. We report a case of congenital chloride diarrhea in a premature female who presented with watery diarrhea containing high concentrations of chloride and abdominal distension.