• Geomechanics and Engineering
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• 제5권2호
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• pp.99-118
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• 2013

Construction of the extension project of the Bangkok MRT Blue Line underground railway was recently started in 2011. The construction of approximately 5 km long underground tunnel and 4 deep excavations of underground station are considered to be the most important geotechnical works. The pressuremeter was selected as a high-quality in situ testing of the soil to evaluate design parameters for the project. In addition, other field and laboratory tests such as vane shear and $CK_0U$ triaxial tests were included in the investigation programme. This paper aims to present the ground conditions encountered along the MRT Blue Line extension project as well as the site investigation and interpretation techniques with particular focus on the pressuremeter tests. The results are also compared with the pressuremeter investigation from the previous Bangkok MRT project.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2004년도 춘계 학술발표회 제16권1호
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• pp.692-695
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• 2004

Seismic performance of reinforced concrete(RC) column bent piers to bidirectional seismic loadings was investigated experimentally. RC column bent piers represent one of the most popular forms of piers used in highway bridges. Further to series of previous experimental researches for the performance of single bridge columns subjected to seismic loadings, four column bent piers were constructed in 400 mm diameter and 2,000 mm height. Each pier has two circular supporting columns. These piers were tested under lateral load reversals with axial load of $0.1f_{ck}A_g$. Bidirectional lateral loadings were applied. The test parameters included: different transverse reinforcement contents and lap-spliced longitudinal reinforcing steels. Test results indicate that lap-splices of longitudinal reinforcing steels have significantly influence on hysteretic response of column bent piers. Column capacity changed with the level of transverse confinement, and bidirectional repeated loadings induced more strength and stiffness degradation than unidirectional repeated loading.

• The Plant Pathology Journal
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• 제20권2호
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• pp.155-157
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• 2004

We isolated Rice dwarf virus (RDV) from infected plants in rice fields (Korea, Japan, China, the Philippines and Nepal) and analyzed their genomic dsRNAs by polyacrylamide gel eletrophoresis. The genomic dsRNAs of the isolates showed distinct electrophoretic mobility profiles. The S12 coding to nonstructural protein of Korean isolate (RDV-Kr) was further analyzed by sequencing. The S12 of RDV-Kr was 1,066bp long and coded for a protein composed of 312 amino acids including three open reading frames of P12, P120Pa and P120Pb. The sequence identities were 96% and 98.6% with Japanese isolates (H, AN), 94.7% with Nepalese isolate (NEL), 94% with Chinese isolate (CK) and the Philippines isolate (P).

• Journal of Information Processing Systems
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• 제8권2호
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• pp.241-262
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• 2012

An understanding of quality attributes is relevant for the software organization to deliver high software reliability. An empirical assessment of metrics to predict the quality attributes is essential in order to gain insight about the quality of software in the early phases of software development and to ensure corrective actions. In this paper, we predict a model to estimate fault proneness using Object Oriented CK metrics and QMOOD metrics. We apply one statistical method and six machine learning methods to predict the models. The proposed models are validated using dataset collected from Open Source software. The results are analyzed using Area Under the Curve (AUC) obtained from Receiver Operating Characteristics (ROC) analysis. The results show that the model predicted using the random forest and bagging methods outperformed all the other models. Hence, based on these results it is reasonable to claim that quality models have a significant relevance with Object Oriented metrics and that machine learning methods have a comparable performance with statistical methods.

• 한국군사과학기술학회지
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• 제24권5호
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• pp.537-544
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• 2021

Cyber threats can bypass existing cyber-protection systems and are rapidly developing by exploiting new technologies such as artificial intelligence. In order to respond to such cyber threats, it is important to improve the ability to detect unknown cyber threats by correlating heterogeneous cyber protection systems. In this paper, to enhance cyber-attack response capabilities, we proposed command and control that enables rapid decision-making and response before the attack objectives are achieved, using Lockheed Martin's cyber kill chain and MITRE ATT&CK to analyze the purpose and intention of the attacker.

• Journal of Information Science Theory and Practice
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• 제7권2호
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• pp.32-39
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• 2019

A convolutional neural network (CNN) has been widely used in facial expression recognition (FER) because it can automatically learn discriminative appearance features from an expression image. To make full use of its discriminating capability, this paper suggests a simple but effective method for CNN based FER. Specifically, instead of an original expression image that contains facial appearance only, the expression image with facial geometry visualization is used as input to CNN. In this way, geometric and appearance features could be simultaneously learned, making CNN more discriminative for FER. A simple CNN extension is also presented in this paper, aiming to utilize geometric expression change derived from an expression image sequence. Experimental results on two public datasets (CK+ and MMI) show that CNN using facial geometry visualization clearly outperforms the conventional CNN using facial appearance only.

• 식품과학과 산업
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• 제50권3호
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• pp.2-32
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• 2017

Due to the increasing demand for convenience and simplicity, Home Meal Replacement (HMR) has become a key trend in the food service industry. This study researched the current consumer trend and analyzed the national and international HMR product trend, aiming to find useful insights for the field. Results showed that in order to expand the HMR market demand, it is possible to consider diversifying the product category by making customized premium products, such as products for the elderly, infants, patients, and sports players, or products with enhanced nutritional fortification. From the industrial aspect, centralization through Central Kitchen (CK) and implementation of the scientific and advanced ISO and HACCP system are necessary. Lastly, to develop high value-added HMR products, it is deemed essential to utilize the so-called 'food tech', the technology which integrates core technologies of the fourth industrial revolution into the food industry.

• 한국수산과학회지
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• 제45권1호
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• pp.1-10
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• 2012

The objective of this study was to investigate the sanitary and nutritional requirements for the industrialization of commercial kwamegi from Pacific herring Clupea pallasii (CK-PH). The proximate composition of CK-PH was 46.4-47.2% moisture, 24.7-25.6% crude protein, 23.6-25.2% crude lipid, and 2.5-2.9% ash, which differed significantly from that of commercial kwamegi from the Pacific saury Cololabis saira. According to the volatile basic nitrogen content, heavy metal content, and viable cell and coliform group counts, products K and F (prepared by a general process) maintained their freshness, whereas product T (treated with green tea extract) did not. Products K and F contained five types of biogenic amine: agmatine sulfate (2,596 and 2,067 mg/kg, respectively), putrescine dihydrochloride (8.5 and 8.0 mg/kg, respectively), cadaverine (3.7 and 3.9 mg/kg, respectively), histamine (17.0 and 12.4 mg/kg, respectively), and spermidine (8.7 and 8.0 mg/kg, respectively). Product T contained six amine types: tyramine (12.5 mg/kg), agmatine sulfate (2,723 mg/kg), putrescine dihydrochloride (29.4 mg/kg), cadaverine (321.6 mg/kg), histamine (45.3 mg/kg), and spermidine (13.6 mg/kg). The total amino acid content of product K (22.16/100g) was 5.8% lower than that of product F. The major amino acids of products K and F were aspartic acid, glutamic acid, leucine, and lysine. No difference was found in the fatty acid composition of products K and F. The major fatty acids in products K and F were 18:1n-9, 20:5n-3, and 22:6n-3. Based on the recommended daily dietary allowances for Koreans, the significant minerals in products K and F were calcium, phosphorus, and magnesium.

• 한국임상수의학회지
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• 제30권3호
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• pp.166-171
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• 2013

본 연구는 개에서 난소자궁절제술과 난소절제술의 실시가 동물의 통증행동과 스트레스에 미치는 영향을 비교하고, 임상적용 가능성을 평가하기 위하여 실시되었다. 13 마리의 건강한 암컷 중 (4.2-5.5 kg) 6 마리의 개에서 난소절제술이 행하여졌고, 7 마리에서 난소자궁절제술이 이루어졌다. 술 후 두 그룹 간에 수술 시간, 마취 시간, 복벽의 절개 길이를 비교하였다. 또한 술 전과 술 후 1, 2, 4, 6, 12, 24 시간째에 Short form of composite measure pain scale (CMPS-SF) 를 사용하여 통증 점수를 측정하였고 혈중 glucose 와 creatine kinase 그리고 cortisol 수치를 측정하였다. 난소자궁절제술을 시행한 그룹에서는 난소절제술을 시행한 그룹에 비해 유의적으로 (p < 0.05) 긴 수술 시간, 마취 시간, 복벽 절개 길이를 나타내었다. Two-way ANOVA test 결과 CMPS-SF에 의한 통증점수가 두 그룹 간에 유의적 (p < 0.05) 차이를 보였으며 술 후 1, 2, 4, 6 시간째 난소절제술을 행한 그룹에서 유의적으로 낮은 수치를 나타내었다. Glucose 의 경우 난소자궁절제술을 행한 그룹에서는 술 전과 비교해 유의적 (p < 0.05) 농도 증가가 술 후 1 시간째에 나타났으나 난소절제술을 행한 그룹에서는 술 후 전체 관찰기간 동안 유의적 농도 증가가 관찰 되지 않았다. Creatine Kinase 의 경우 난소자궁절제술을 행한 그룹에서는 술 전과 비교하여 술 후 1, 2, 4, 6, 12 시간째에 유의적 (p < 0.05) 농도 증가를 나타내었으나 난소절제술 그룹의 경우 술 후 4, 6, 12 시간째에만 술 전과 비교하여 유의적 (p < 0.05) 농도 증가를 나타내었다. Cortisol 의 경우 두 그룹 모두 술 후 1, 2 시간째에 유의적인 (p < 0.05) 농도 상승을 나타내었다. 본 연구 결과 난소절제술을 이용한 암캐의 중성화 수술 방법은 난소자궁절제술에 비해 짧은 복벽 절개, 수술 시간, 마취 시간을 요하며, 적은 술 후 통증과 스트레스를 유발하므로 난소절제술을 시행하는 것이 환자에게 바람직할 것으로 판단된다.

• Parasites, Hosts and Diseases
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• 제56권2호
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• pp.135-145
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• 2018

Due to the critical location and physiological activities of the retinal pigment epithelial (RPE) cell, it is constantly subjected to contact with various infectious agents and inflammatory mediators. However, little is known about the signaling events in RPE involved in Toxoplasma gondii infection and development. The aim of the study is to screen the host mRNA transcriptional change of 3 inflammation-related gene categories, PI3K/Akt pathway regulatory components, blood vessel development factors and ROS regulators, to prove that PI3K/Akt or mTOR signaling pathway play an essential role in regulating the selected inflammation-related genes. The selected genes include PH domain and leucine- rich-repeat protein phosphatases (PHLPP), casein kinase2 (CK2), vascular endothelial growth factor (VEGF), pigment epithelium-derived factor (PEDF), glutamate-cysteine ligase (GCL), glutathione S-transferase (GST), and NAD(P)H: quinone oxidoreductase (NQO1). Using reverse transcription polymerase chain reaction (RT-PCR) and quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR), we found that T. gondii up-regulates PHLPP2, $CK2{\beta}$, VEGF, GCL, GST and NQO1 gene expression levels, but down-regulates PHLPP1 and PEDF mRNA transcription levels. PI3K inhibition and mTOR inhibition by specific inhibitors showed that most of these host gene expression patterns were due to activation of PI3K/Akt or mTOR pathways with some exceptional cases. Taken together, our results reveal a new molecular mechanism of these gene expression change dependent on PI3K/Akt or mTOR pathways and highlight more systematical insight of how an intracellular T. gondii can manipulate host genes to avoid host defense.