• Korean Journal of Medicinal Crop Science
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• v.28 no.6
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• pp.471-480
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• 2020

Background: The roots of Cirsium japonicum var. ussuriense (RCJ) have been used as traditional medicine in Korea for hematuria and hematemesis. These extracts exert anti-oxidative and anti-inflammatory effects by scavenging for free radical and regulating the inflammatory response. However, the effect of RCJ on rheumatoid arthritis (RA) has not been elucidated. Thus, we evaluated the water extract of RCJ (WRCJ) using type II collagen-induced RA models. Methods and Results: RA was induced by immunization with type II collagen. All experimental materials were orally administered daily for three weeks. The positive control group was administered with 0.2 mg/kg methotrexate (n = 7), while the experimental group was administered with WRCJ (100 or 500 mg/kg, n = 7). Serum levels of TNF-alpha, Interleukin 6 (IL-6), and type II collagen IgG (CII) were measured using ELISA. Administration of 500 mg/kg WRCJ decreased the levels of TNF-alpha, IL-6, and CII. Moreover, WRCJ treatment diminished swelling of hind legs and infiltration of inflammatory cells in RA models' synovial membrane. Conclusions: These results indicate that WRCJ could improve RA, reduce inflammatory indicators and synovial inflammation. However, further experiments are required to determine how WRCJ can influence the signal transduction pathway in RA.

• International conference on construction engineering and project management
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• 2020.12a
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• pp.201-206
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• 2020

Diversification of project delivery methods (PDM) under ever-changing construction business environment has significantly changed the role of project participants. Active efforts to effectively sharing the roles and responsibilities have been observed in the project management offices (PMOs) among owner/operator organizations as well as engineering, procurement, construction and maintenance (EPCM) firms. In order for being effective in a holistic way throughout the project life-cycle, a PMO needs to have 'adequate management skills' as well as 'essential technical capabilities' in cooperating with many different participants. One of the well-known examples of the PMO's tool to support these skills and capabilities is the effective 'work packaging (WP)' that serves as a common basis integrating all relevant information in a structured manner. In an attempt to enhance the construction productivity, the concept of 'advanced work packing (AWP)' has been introduced by Construction Industry Institute (CII). The AWP enables productivity to be improved by early planning of construction packages in the design phase "with the end in mind". The purpose of this study is to identify and evaluate the 'variables' of advanced work packing (AWP) for life-cycle information integration. Firstly, an extended concept of advanced WP based on the CII AWP was defined in order to comprehend many different issues of business functions (e.g. cost, schedule, quality, etc.). A structured list of major components and variables of AWP were then identified and examined for practical viability with real-world examples. Strategic fits and managerial effectiveness were stressed throughout the analyses. Findings, implications and lessons learned are briefly discussed as well.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2021.11a
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• pp.201-202
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• 2021

Regulations on greenhouse gases emitted from ships in international shipping are being strengthened, and the greenhouse gas reduction target established by the International Maritime Organization is acting as a great challenge for shipping companies in terms of technical and operational aspects. The International Maritime Organization aims to reduce carbon intensity by 30% by 2030, 70% by 2050, and by 50% in terms of gross emissions compared to 2008. To realize this situation, the IMO adopted some short-term and mid-to-long-term measures and adopted technical measures such as the application of EEXI, an energy efficiency index, to existing ships from 2023, and the early application of EEDI phase 3 for some tpe of ships. In addition, reduction measures were introduced to reduce greenhouse gas in the operational aspect.

• The korean journal of orthodontics
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• v.31 no.1 s.84
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• pp.39-50
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• 2001

In proceeding with orthodontic treatment, the prediction for the shape, growth rate and growth direction of mandible plays a major role to set up the treatment plan and determine its period and prognosis. Various approaches being made so far have shown that the linear and angular measurement using lateral cephalograms are relatively accurate to estimate them. This study was purposed to find the shape of mandible more clearly by preventing the overlap of the Condyle head area which appears in lateral cephalogram, and to estimate its growth rate by comparing the growth quantity and ratio via lateral area measurement. This experimental was performed against 40 patients total, of which Class I of 14, Class II of 9 and Class III of 17 consist. Wide open lateral cephalograms of 40 patients were taken over average period of 4 Year 3 Months, then the linear and angular measurements were carried out with 11 itemized lists. Autocad Rl4 application program was utilized to draw their appearance, measure and compare their lateral area. As a result of study, conclusions were made as follows; 1. Mandibular body length (gonion-menton) tended to increase in order of CIII, CI and CII, and Mandibular body length of CIII group had a tendency to grow twice faster than that of CII group. 2. In lateral items such as Go-Me, A-Cd, B-Cp, E-F and G-H, CIII showed a significant increase on the year-average quantity and rate of the growth, and especially apparent difference was observed in CIII group rather than CII group. 3. For the 4 Year 3 Months period, the year-average growth quantity of lateral area of the mandible was $1.0cm^2$ for Class I, $0.8cm^2$ for Class II and $1.4cm^2$ for Class III, which corresponds to $11.9\%,\;11.8\%\;and\;20.3\%$ of growth ratio respectively. Thus, growth ratio almost 2 times more than other groups was observed in group CIII while growth ratio between group CI and CII has little difference. 4. Considering the results as above, it can be proposed that the difference in size of the mandible between groups is caused by the difference in the growth rate and growth quantity of the mandible, which generated in the middle of growth, rather than the difference in size of congenital Jaw-bone.

• Journal of Oral Medicine and Pain
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• v.11 no.1
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• pp.19-27
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• 1986

Registration of the mandibular movement in patients with temporomandibular joint noise (clicking and/or crepitus) was performed using one of mandibular tracking devices(SAPHON VISI-TRAINER CII,Tokyo Shizai-sha Inc.,Japan). The obtained results were follows : 1. In many cases, the movement pattern of light emitting diode(LED) attached on the mandibular midline showed lateral deviation from a vertical reference line which was pronounced in association with TMJ noise during opening and closing. 2. In patients with unilateral TMJ noise the mandibular midline usually towards the side demonstrating TMJ noise during opening. 3. A distinct V-shaped discontinuity in the trace of velocity of mandibular movement was found at the point of the TMJ noise. 4. In patients with TMJ noise the velocity of mandibular movement at the point of the TMJ noise was decreased rapidly. 5. In several cases, TMJ noise could be eliminated by traning of Rocabado`s control of TMJ rotations.

• Architectural research
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• v.8 no.1
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• pp.57-68
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• 2006

Global competition and reduced project life cycle ultimately puts greater performance requirements on the capital project delivery systems used to maintain competitiveness. Despite continuing improvements in delivery cycle time, business owners of facilities continue to demand greater improvements in project delivery cycle time. Therefore, it is very important to investigate the various techniques and methods leading to reduction in project cycle time and also identify the applicability of identified techniques and methods. This paper introduces reduction techniques identified through literature review (i.e, Schedule Reduction Techniques (SRTs), Management Techniques (MTs), and Construction Institute Industry (CII) Best Practices (BPs). In order to collect applicability of these techniques under different project phases (Pre-project planning (PPP), Design (D), Material Management (MM), Construction (C), and Start-up (SU)), the Essence Applicability Matrices (EAM) is used.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2004.11a
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• pp.89-94
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• 2004

Many innovative management processes, which are also termed as best practices or value improving practice, have been proven to successfully improve the value of capital facility projects. With a lack of any guidance on how to implement the most suitable value management process for a particular project, the objective of this paper is to facilitate the VMP implementation. A CII (Construction Industry Institute)'s recent study, titled as 'Development of the Value Management Toolkit,' encompasses a comprehensive structure of value management and provides a new methodology in optimizing the implementation of the value management processes in order to leverage the unique project circumstances, such as project objectives, resource availability, and site limitations, etc. As a pioneering study, the findings contribute to the expedition of implementing value management processes in the industry and maximize the potential benefits in applying the most benefiical value management process for a particular capital facility project.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.55 no.6
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• pp.259-264
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• 2006

This paper addresses the collusive bidding that functions as a potential obstacle to a fully competitive wholesale electricity market. Cooperative game is formulated and the equation of its Nash Equilibrium (NE) is derived on the basis of the supply function model. Gencos' willingness to selectively collude is expressed through a bargain theory. A Collusion Incentive Index(CII) for representing the willingness is defined through computing the Gencos' profits at NE. In order to keep the market non-cooperative, the market operator has to know the highest potentially collusive combination among the Gencos. Another index, which will be called the Collusion Monitoring Index(CMI), is suggested to detect the highest potential collusion and it is calculated using the marginal cost functions of the Gencos without any computation of NE. The effectiveness of CMI for detecting the highest potential collusion is verified through application on many test market cases.

• Journal of the Korean Institute of Telematics and Electronics C
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• v.34C no.9
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• pp.1-9
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• 1997

Novel class A CMOS second-generation current conveyors (CCII) using 0.6.mu.m n-well standard CMOS process for high-frequency current-mode signal processing were developed. The CCII consists of a regulated current-cell for the voltage input and a cascode current mirror for the current output. In this architecture, the two input stages are coupled by current mirrors to reduce the current input impedance. Measurements of the fabricated cCII show that the current input impedance is 308 .ohm. and the 3-dB cutoff frequency when used as a voltage amplifier extends beyond 10MHz. The linear dynamic ranges of voltage and current are from -0.5V to 1.5V and from -100.mu.A to +120.mu.A for supply voltage V$\_$DD/ = -V$\_$SS/=2.5V, respectively. The power dissipation is 2 mW and the active chip area is 0.2 * 0.2 [mm$\^$2/].

• Proceedings of the Korean Institute of Building Construction Conference
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• 2016.05a
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• pp.168-169
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• 2016

Risk management at an early stage of projects is known as an effective method expected various benefits. The PDRI(Project Definition Rating Index) by the CII(Construction Industry Institute) is defined project scope for reducing risks. In addition, the PDRI is one of the verified methods for achieving benefits by a risk management. The literature review in Korea about risk management is all about focusing on construction works and the construction phase. Thus, we need to extend the perspective of a project management such as the PDRI. To develop the Korean PDRI, However, we have to consider Korean situations. Therefore, in this study, we analyze some previous studies of PDRI' indexes and its using methods, and suggest the new direction for using PDRI in Korea. This method will enable to improve the scoring method of a project management with PDRI in Korea.