• Journal of Acupuncture Research
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• v.19 no.2
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• pp.92-104
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• 2002

Objective : Bee venom (BV) has traditionally been used in Oriental medicine to relieve pain and to treat inflammatory disease such as rheumatoid arthritis (RA). Autoimmunity to type II collagen (CII) may involve in the pathogenesis of RA. This study was performed to evaluate the effect of BV on type II collagen induced arthritis (CIA) with the naked eye, a immunohistochemical method and the examination of histology. Method : Male mice were immunized by subcutaneously injection of an $200{\mu}g$ emulsion mixed with bovine CII and complete Freund's adjuvant (CFA) twice for two weeks. In the control group, normal saline was injected, and in the experimental group, BV was applied. Result : The incidence of arthritis, the mean arthritis index and the number of the arthritic limbs of the BV group were all significantly lower than those of the control group. Among the pro-inflammatory cytokines, the production of $TNF-{\alpha}$ in the BV group was also suppressed compared with the control group, but $IL-1{\beta}$ was not. The examination on the histopathology of joints of CIA mice showed the effect of Bee Venom Herbal Acupuncture on the arthritis. Conculusion : Treatment with BV resulted in inhibition of development of arthritis and immune responses to CII.

• Journal of Acupuncture Research
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• v.22 no.2
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• pp.33-41
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• 2005

Objective : The effect of Ulmus davidiana Planch(UD), which has long been known to have anti-inflammation and protective effects on damaged tissue, inflammation and bone among other functions, on the development of type II collagen (CII)-induced arthritis (CIA) in rats was studied. Methods : Male rats were immunized with an emulsion of $200\;{\mu}g$ of CII and complete Freund's adjuvant (CFA). The rats were then given intraperitoneal stimulation of Ulmus davidiana Planch herbal acupuncture(UDHA)or saline during the experiment. When compared with rats treated with saline as control, UDHA at doses of more than $20{\mu}g/100\;g$ rat once a day for 7 days inhibited the ability of inguinal lymph node cells to produce T cell cytokines interleukin-2, interleukin-6, $IFN-{\gamma}$ when the cells were obtained from rats 14 days after immunization and cultured in vitro with CII. Results : When rats were injected intraperitoneally, UD -treated group and control group rats did not differ significantly when low doses of UD was given to rats. Conclusion : The recommended dose of UD in the management and treatment of rat CIA will be more than $20{\mu}g/100\;g$, which is two-firth of human therapeutic dose. From the results, it was concluded that the effect of UDHA is dependent of dosage.

• Journal of the Korean Wood Science and Technology
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• v.26 no.4
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• pp.78-85
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• 1998

The antifungal activity of methanol extracts against dermatophytes was the highest at root-bark methanol extract, and the highest inhibitory effect was revealed in petroleum ether fraction of root-bark methanol extract. Compound I and compound II with significant antifungal activity were isolated from the fractions by silica gel column chromatography. As a result of the instrumental analyses, compound I and compound II were already known alkaloids. Compound I was identified as 4-methoxyfuro[2,3-6]quinoline (dictamnine ; $C_{12}H_9NO_2$) and compound II was identified as 4-methoxy-lmethyl-2(1H)-quinolinone ($C_{11}H_{11}NO_2$). The MIC of compound I against T. mentagrophytes and T. rubrum was $40{\mu}g/m\ell$ and the MIC of compound II against the same fungi was $800{\mu}g/m\ell$.

• Journal of Astronomy and Space Sciences
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• v.15 no.2
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• pp.335-340
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• 1998

We obtained UV light curves of 44i Bootis, a W UMa type star from the IUE low dispersion spectra. In order to investigate variations of the emission lines from chromospheric activity and transition region, UV line intensity has been measured for CI, CII, ClV, SiIV, HeII lines. Through plotting the line intensity with the orbital phase, we found that emission lines showed maximum at $0^p.2;and;0^p.8$ of the light curves, indicating the chromospheric activity of contact binary, 44i Bootis. We found that the light curves of UV emission lines is strongly modulated by the variation of chromospheric activities of 44i Bootis.

• Journal of KIISE:Computer Systems and Theory
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• v.28 no.8
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• pp.372-378
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• 2001

오늘날, 이질적인 분산 컴퓨팅 환경을 통합하고 분산 공유 자원을 효율적으로 사용할 수 있는 공통 작업 환경에 대한 요구가 날로 높아지고 있다. 이러한 연구 중에서 주목받는 것 중 하나가 OMG의 CORBA이다. CORBA 시스템에서 실시간 멀티미디어 데이터들을 처리하기 위해 확장된 CORBA 표준을 RT(Real-Time) CORBA라고 한다. RT CORBA의 핵심은 수많은 실시간 태스크들의 블록을 최대한 방지하여 실시간 QoS를 보장해 줄 수 있는 실시간 스케쥴링 기법에 있다고 할 수 있다. 현재 RT CORBA를 위해 제안되는 많은 스케쥴링 기법들은 대개 이전의 단일 시스템에 기반한 전역 우선순위 기반 스케쥴링이 대부분이다. 하지만 이러한 Soft Real-Time 스케쥴링은 다양한 성능 요소가 산재하는 분산 시스템에서는 그 성능을 보장할 수 없다. 본 논문에서는 CORBA와 같은 분산시스템의 보편적 특성을 고려한 Hard Real-Time 스케쥴링 기법인 CII(Cut In Interval) 기법을 제안하였다. 기존의 전역 우선순위 바탕의 스케쥴링이 비효율적인 태스크 할당 및 지역 스케쥴링을 제공하지만, CII 기법의 스케쥴링은 간단하면서도 보다 효과적인 전역 스케쥴링을 제공할 수 있다. CII 기법의 핵심은 이미 스케쥴링된 태스크를 가능한 제한시간까지 연기하여 얻어진 여유시간을 다른 실시간 태스크들의 처리에 활용하자는 것이다. 이러한 여유시간의 활용은 제안한 기법이 기존의 기법과 달리 보다 능동적이고 효율적인 스케쥴링 기법임을 증명한다.

• The Journal of Advanced Prosthodontics
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• v.11 no.5
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• pp.271-279
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• 2019

PURPOSE. The newest technologies for digital implant impression (DII) taking are developing rapidly and showing acceptable clinical results. However, scientific literature is lacking data from clinical studies about the accuracy of DII. The aim of this study was to compare digital and conventional dental implant impressions (CII) in a clinical environment. MATERIALS AND METHODS. Twenty-four fixed zirconia restorations supported by 2 implants were fabricated using conventional open-tray impression technique with splinted transfers (CII group) and scan with Trios 3 IOS (3Shape) (DII group). After multiple verification procedures, master models were scanned using laboratory scanner D800 (3Shape). 3D models from conventional and digital workflow were imported to reverse engineering software and superimposed with high resolution 3D CAD models of scan bodies. Distance between center points, angulation, rotation, vertical shift, and surface mismatch of the scan bodies were measured and compared between conventional and digital impressions. RESULTS. Statistically significant differences were found for: a) inter-implant distance, b) rotation, c) vertical shift, and d) surface mismatch differences, comparing DII and CII groups for mesial and distal implant scan bodies ($P{\leq}.05$). CONCLUSION. Recorded linear differences between digital and conventional impressions were of limited clinical significance with two implant-supported restorations.

• Journal of Acupuncture Research
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• v.22 no.2
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• pp.93-101
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• 2005

Objective: We have evaluated UDHA into the joint for its effectiveness on immune responses to CII in the rat CIA. In an attempt to gain further insight into the mode of action of UDHA, we also investigated the effects of UDHA on the incidence and development of arthritis in rat CIA with 2 different regimens: (1) started prior to a primary immunization, (2) started on the day of a primary immunization. Methods : Male rats were immunized with an emulsion of $200\;{\mu}g/100g$ of CII and complete Freund's adjuvant (CFA). The rats were then given intraperitoneal(i.p) stimulation of Ulmus davidiana Planch herbal acupuncture(UDHA) or saline during the experiment. Lymph node cells were obtained from rats 14 days after immunization and cultured in vitro with CII. When compared with rats treated with saline as control, UDHA at doses of more than $20\;{\mu}g/100\;g$ rat once a day for 7 days inhibited the ability of inguinal lymph node cells to produce T cell cytokines interleukin-$1{\beta}$, tumor necrosis $factor-{\alpha}$ $(TNF-{\alpha})$. When rats were injected intraperitoneally with SRBC, hemaglutination titers in UD-treated and control rats did not differ significantly when low doses of UD was given to rats. However, i.p injection of UD at doses of more than $10\;{\mu}g/100\;g/day$ for 7 days slightly suppressed antibody production. Results : The present results show that treatment with UDHA can inhibit the onset and development of arthritis and the immune responses to collagen. Conclusion: Therapeutic i.p injection with UD affect the clinical course of the disease and the immune responses to CII.

• Construction Engineering and Management
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• v.4 no.2 s.14
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• pp.30-33
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• 2003

• Construction Engineering and Management
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• v.16 no.2
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• pp.52-55
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• 2015

• Construction Engineering and Management
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• v.8 no.2
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• pp.20-23
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• 2007