• Animal Bioscience
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• 제34권1호
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• pp.154-160
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• 2021

Objective: The effect of environmental enrichment on the behaviour of piglets in the nursery phase was evaluated. Methods: A total of 450 hybrid pigs (21 day old), including both females and uncastrated males, weighing approximately 6 kg, were distributed in a completely randomised design with 3 treatments and 3 replicates of 50 animals each. The treatments were: i) pen without environmental enrichment (control), ii) treatment consisting of continuous environmental enrichment (CEE) with rubber balls throughout the experimental period, and iii) treatment consisting of environmental enrichment with washed balls (EEWB) during the whole experimental period which were removed daily for washing. For the behavioural evaluation, 10 animals were randomly selected per replicate. The behavioural assessments were performed once a week, from 8 am to 6 pm, using images captured with a video camera. The data were submitted to non-parametric analyses, the means were compared using the Bonferroni test, and Person's correlations were also calculated. Results: A statistical difference (p = 0.001) was observed in the B5 (playful) behaviour; the animals in the EEWB treatment group had a higher frequency of this behaviour than animals in the control treatment group. The animals in the control group showed a higher frequency of B7 behaviour (lying down) (p = 0.026) than those in the EEWB and CEE treatment groups. The animals in the control group had a higher frequency of the B9 (belly nosing) behaviour than those in the EEWB group (p = 0.015). There was a tendency towards a higher frequency of behaviour B3 (walking in the pen) (p = 0.067) when the animals received the control treatment than treatments EEWB or CEE. Conclusion: The use of an enriching object improved the animal welfare and altered the correlation between the evaluated behaviours compared to the animals that did not have environmental enrichment.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2000년도 하계학술대회 논문집 D
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• pp.2696-2698
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• 2000

본 연구에서는 실수형 염색체들로 구성된 개체에 대해 감수분열을 적용하여 개체를 만들고, 이 생식체들의 랜덤한 선택과 교배에 의해 세대가 진화함에 따라 탐색을 수행하는 감수분열 유전알고리즘을 이용하여 퍼지모델의 최적 구조와 파라미터를 탐색하고 Gradient Descent 알고리즘으로 파라미터를 정밀 조정하는 방안을 제안한다. 제안된 방안을 적용하여 Box-Jenkins의 가스로 데이터에 대한 퍼지모델을 구성하고 그 적용 가능성을 보인다.

• 멤브레인
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• 제24권2호
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• pp.167-175
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• 2014

수증기 투과성과 DMMP 방호성능을 가지는 cellulose acetate butyrate (CAB)/polyethyleneimine (PEI) 기반의 선택투과막에 대해 여러가지 첨가제를 적용하여 CEES에 대한 방호성능 개선을 시도하였다. 시험결과, CAB/PEI 기반의 선택투과막은 수증기 투과성은 그대로 유지하면서(${\geq}1,800g/m^2/day$), CEES에 대한 방호성능의 개선을 보여주었다($7.1{\sim}11.5{\mu}g/cm^2{\cdot}24hr$). 이 중, $Ag^+$ 이온과 이온교환수지 혼합물을 포함한 CAB/PEI 선택투과막에서 가장 우수한 방호성능을 확보하였다. 그리고 시험한 모든 선택투과막은 생물학작용제를 모사할 수 있는 다양한 크기의 에어로졸 입자($0.005{\sim}3{\mu}m$)에 대해서도 방호성능을 가짐을 확인하였다.

• 대한통합의학회지
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• 제9권4호
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• pp.11-18
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• 2021

Purpose : The purpose of this study was to investigate the effect on lung capacity of healthy men and women in their twenties by performing an intervention using the chest extension exercise and the bridge exercise, which are respiratory muscle strengthening exercises. Methods : Thirty adult men and women in their 20s participated in this study. All subjects participated in the study after hearing the explanation of the purpose and method of the study, filling out a consent form. All subjects were randomly assigned to the chest extension exercise (CEE) group and the bridge exercise (BE) group of fifteen each. Each exercise was performed twice a week for 4 weeks. Lung capacity was measured by forced vital capacity (FVC) and forced expiratory volume in one second (FEV₁) using spirometry. Lung capacity was measured before and after exercise. The measured data were compared through the dependent t-test and the independent t-test. The statistical significance level was set at .05. Results : After the intervention, the CEE group showed a significant increase in FVC and FEV₁ compared to before the intervention (p<.05). After the intervention, the BE group also had a significant increase in FVC and FEV₁ compared to before the intervention (p<.05). However, there was no difference in FVC and FEV₁ between groups before and after the intervention (p>.05). Conclusion : There was no difference between groups in lung capacity after exercise. However, both the chest extension exercise and the bridge exercise increased FVC and FEV1, which was thought to be because both exercise methods were effective in increasing lung capacity. Therefore, both chest extension exercises and bridge exercises can be effectively applied as a way to increase lung capacity.

• Journal of Veterinary Science
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• 제19권6호
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• pp.759-770
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• 2018

Fowl adenovirus (FAdV) is distributed worldwide and causes economic losses in the poultry industry. The objectives of this study were to determine the hexon and fiber gene changes in an attenuated FAdV isolate from Malaysia in specific pathogen-free chicken embryonated eggs (SPF CEE) and its infectivity in commercial broiler chickens. SPF CEE were inoculated with 0.1 mL FAdV inoculum via the chorioallantoic membrane (CAM) for 20 consecutive passages. The isolate at passage 20 (E20), with a virus titer of $10^{8.7}TCID_{50}/mL$ ($TCID_{50}$, 50% tissue culture infective dose), was inoculated (0.5 mL) into one-day-old commercial broiler chicks either via oral or intraperitoneal routes. The study demonstrated that 100% embryonic mortality was recorded from E2 to E20 with a delayed pattern at E17 onwards. The lesions were confined to the liver and CAM. Substitutions of amino acids in the L1 loop of hexon at positions 49 and 66, and in the knob of fiber at positions 318 and 322 were recorded in the E20 isolate. The isolate belongs to serotype 8b and is non-pathogenic to broiler chickens, but it is able to induce a FAdV antibody titer. It appears that molecular changes in the L1 loop of hexon and the knob of fiber are markers for FAdV infectivity.

• 생약학회지
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• 제51권4호
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• pp.349-359
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• 2020

Gastroesophageal reflux disease (GERD) is a disease that stomach contents continually refluxing, and is currently on the rise worldwide. The purpose of this study is to find natural materials that can reduce side effects and effectively treat chronic acid reflux esophagitis (CARE), one of GERD. First, the antioxidant activity was confirmed by varying the mixing ratio of Coptidis Rhizoma and Evodiae Fructus, which are effective against chronic reflux esophagitis. After, animal experiments were conducted using a 1:1 (CE) and 1:2 (CEE) combination ratio of Coptidis Rhizoma and Evodiae Fructus, which had the best antioxidant efficacy. Gross lesion of esophageal mucosa after CE or CEE treatment showed a superior enhancement compared with that of CARE control rats. Additionally, its inhibited MAPK phosphorylation and led NF-κB inactivation through the suppression of IκBα phosporylation by regulating Nrf2/Keap-1, and NF-κB inactivation induced reduced protein expressions including inflammatory mediators and cytokines. Moreover, its improved esophageal barrier function through upregulating protein expressions of tight junction protein, whereas downregulating protein expressions of MMPs. Taken together, a mixture of Coptidis Rhizoma and Evodiae Fructus can attenuate the esophageal mucosal ulcer by inhibiting MAPK and NF-κB pathway, and upregulating proteins associated with tight junction.

• 디지털융복합연구
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• 제20권4호
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• pp.389-396
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• 2022

딥러닝(Deep Learning)은 퍼셉트론을 기반으로 하고 있으며 현재에는 이미지 인식, 음성 인식, 객체 검출 및 약물 개발 등과 같은 다양한 영역에서 사용되고 있다. 이에 따라 학습 알고리즘이 다양하게 제안되었고 신경망을 구성하는 뉴런수도 연구자마다 많은 차이를 보이고 있다. 본 연구는 현재 대표적으로 사용되고 있는 확률적 경사하강법(SGD), 모멘텀법(Momentum), AdaGrad, RMSProp 및 Adam법의 뉴런수에 따른 학습 특성을 분석하였다. 이를 위하여 1개의 입력층, 3개의 은닉층, 1개의 출력층으로 신경망을 구성하였고 활성화함수는 ReLU, 손실 함수는 교차 엔트로피 오차(CEE)를 적용하였고 실험 데이터셋은 MNIST를 사용하였다. 그 결과 뉴런수는 100~300개, 알고리즘은 Adam, 학습횟수(iteraction)는 200회가 딥러닝 학습에서 가장 효율적일 것으로 결론을 내렸다. 이러한 연구는 향후 새로운 학습 데이터가 주어졌을 경우 개발될 알고리즘과 뉴런수의 기준치에 함의를 제공할 것이다.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2010년도 추계 학술발표회
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• pp.808-812
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• 2010

A great deal of attention is focused on coupled Thermo-Hydro-Mechanical (THM) behavior of multiphase porous media in diverse geo-mechanical and geo-environmental areas. This paper presents general governing equations for coupled THM processes in unsaturated porous media. Coupled partial differential equations are derived from 3 mass balances equations (solid, water, and air), energy balance equation, and force equilibrium equation. Finite element code is developed from the Galerkin formulation and time integration of these governing equations for 4 main variables (displacement $\underline{u}$, gas pressure $P_g$, liquid pressure $P_l$), and temperature T). The code is validated with theoretical solutions for linear material with simple boundary conditions.

• Structural Engineering and Mechanics
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• 제13권3호
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• pp.241-260
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• 2002

The effect of shear coupled with axial force variation on the inelastic seismic behaviour of reinforced concrete bridge piers is investigated in this paper. For this purpose, a hysteretic axial-shear interaction model was developed and implemented in a nonlinear finite element analysis program. Thus, flexure-shear-axial interaction is simulated under variable amplitude reversed actions. Comparative studies for shear-dominated reinforced concrete columns indicated that a conventional FE model based on flexure-axial interaction only gave wholly inadequate results and was therefore incapable of predicting the behaviour of such members. Analysis of a reinforced concrete bridge damaged during the Northridge (California 1994) earthquake demonstrated the importance of shear modelling. The contribution of shear deformation to total displacement was considerable, leading to increased ductility demand. Moreover, the effect of shear with axial force variation can significantly affect strength, stiffness and energy dissipation capacity of reinforced concrete members. It is concluded that flexure-shear-axial interaction should be taken into account in assessing the behaviour of reinforced concrete bridge columns, especially in the presence of high vertical ground motion.

• 천문학회보
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• 제42권2호
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• pp.51.4-52
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• 2017

We present the derived kinematic characteristics of low-${\alpha}$ thin-disk and high-${\alpha}$ thick-disk stars in the Milky Way, investigated with a sample of about 33,900 G- and K-type dwarfs from the Sloan Extension for Galactic Understanding and Exploration (SEGUE). Based on the level of ${\alpha}$-element enhancement as a function of [Fe/H], we separate our sample into thin- and thick-disk stars and then derive mean velocity, velocity dispersion, and velocity gradients for the U, V and W velocity components, respectively, as well as the orbital eccentricity distribution. There are notable gradients in the V velocity over [Fe/H] in both populations: -23 km s-1 dex-1 for the thin disk and +44 km s-1 dex-1 for the thick disk. The velocity dispersion of the thick disk decrease with increasing [Fe/H], while the velocity.