• Title/Summary/Keyword: CD38

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RGB White Organic Light Emitting Diode with a Color Control Layer

  • Lee, Jeong-Ik;Chu, Hye-Yong;Yang, Yong-Suk;Lee, Mi-Do;Chung, Sung-Mook;KoPark, Sang-Hee;Hwang, Chi-Sun
    • 한국정보디스플레이학회:학술대회논문집
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    • 2006.08a
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    • pp.1587-1590
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    • 2006
  • Through the engineering of recombination region and energy transfer in organic light emitting device, blue and red light emitting device with good color stability has been successfully obtained. A Color control layer (CCL), which emits green light through the energy transfer from the emission layers, has been introduced into the blue and red light emitting device for RGB white OLED. The RGB white OLED showed the current efficiency of 13 cd/A and the CIE coordinates of (0.33, 0.38) at $1000\;cd/m^2$. The device exhibited very stable spectrum with respect to operating current density and the CIE coordinates varied from (0.34, 0.38) to (0.31, 0.37) for $100-22000\;cd/m^2$.

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A Study on the Magneto-optical Properties and Application of Diluted Magnetic Semiconductor Cd1-xMnxTe (묽은 자성 반도체 Cd1-xMnxTe의 자기 광학적 특성과 응용성 연구)

  • Hwang, Young-Hun;Um, Young-Ho;Cho, Sung-Lae
    • Journal of the Korean Magnetics Society
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    • v.19 no.5
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    • pp.186-190
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    • 2009
  • We investigated the magneto-optical properties and application of diluted magnetic semiconductors Cd$_{1-x}$Mn$_x$Te crystals with various Mn contents grown using a vertical Bridgman method. This material crystallizes in the zinc-blende structure for values of x < 0.82. The band-gap energy was depended on Mn mole fraction x linearly and increased with decreasing temperature. The Faraday rotation was increased as the photon energy increased near to that of the fundamental band gap and its increased with increasing Mn mole fraction. Optical isolator using the Cd$_{0.62}$Mn$_{0.38}$Te crystal shows that the isolation and insertion loss are 45 dB and 0.35 dB at 650 nm, respectively.

Gastritis Associated with Initially Pediatric Crohn's Disease and Ulcerative Colitis

  • Basturk, Ahmet;Artan, Reha;Yilmaz, Aygen;Gelen, Mustafa T.
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.21 no.3
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    • pp.163-169
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    • 2018
  • Purpose: The aim of this study is to determine the involvement of the upper gastrointestinal system (GIS) in patients diagnosed with Crohn's disease (CD), ulcerative colitis (UC), and non-inflammatory bowel disease (IBD) and to compare their differences. Methods: This study included patients aged between 2 and 18 years who underwent colonoscopy and esophagogastroduodenoscopy (EGD) for the first time due to the prediagnosis of IBD. In EGD, samples were taken from duodenum, antrum, corpus, and esophagus; and gastritis, duodenitis, and esophagitis were identified through histopathologic examination. The data gathered the ends of the research were compared between IBD with non-IBD groups and between CD-UC with non-IBD groups, and the presence of significant differences between groups were determined. Results: In our study, 16 patients were diagnosed with CD, 13 with UC, 3 with undeterminate colitis, and 13 with non-IBD. In the histopathological examination of the groups, GIS involvement was found in 94.1% of patients diagnosed with IBD and in 38.5% of non-IBD patients. Moreover, the difference was found to be statistically significant (p=0.032). No significant difference was found between the CD and UC groups. Gastritis was mostly observed in 93.8% of CD-diagnosed patients, 76.8% of UC-diagnosed patients, 81.2% of IBD-diagnosed patients, and 38.5% of non-IBD-diagnosed patients. On the other hand, significant differences were found between CD and non-IBD groups (p=0.03), UC and non-IBD groups (p=0.047), and IBD and non-IBD groups (p=0.03). Conclusion: The results of the study show that gastritis was highly observed in UC- and CD-diagnosed patients than in non-IBD-diagnosed patients.

Effect of Peripheral Blood CD4 + CD25 + Regulatory T Cell on Postoperative Immunotherapy for Patients with Renal Carcinoma

  • Zhang, Chao-Hua;Huang, Yan
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.4
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    • pp.2027-2030
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    • 2016
  • Objective: To investigate the effect of peripheral blood CD4 + CD25 + regulatory T cell on postoperative immunotherapy in patients with renal carcinoma. Methods: 38 patients with renal cell carcinoma were recruited, and 20 patients from the operation group purely underwent the radical nephrectomy therapy, 18 patients from the combined group successively underwent the radical nephrectomy therapy and IFN-${\alpha}$ adjuvant immunotherapy. Additionally, 12 healthy subjects were recruited in the same period of time and regarded as the control group. Flow cytometry was used to detect CD4 +, CD8 +, CD4 + CD25+ T lymphocyte subset content and the ratio of all parts in the pre-operative period, in the first post-operative week and in the third post-operative month, compare and analyze its variation trend. Results: The CD4+CD25+ T lymphocyte subset content of individual renal carcinoma patients was significantly higher than that of the control group, also increases with the progression in the tumor stage (P<0.05). The post-operative CD4 + CD25+T lymphocytes of individual operation group and combined group patients showed different degrees of increment, but the increment of the combined group was significantly lower than that of the operation group (P<0.05). For the combined group patients with less pre-operative CD4 + CD25+T lymphocytes, their levels would increase after the immunotherapy, while the pre-operative patients with more CD4 + CD25+ T lymphocytes were the opposite situation. Conclusion: The detection of peripheral blood CD4+CD25+ regulatory T lymphocyte subset can reflect the anti-tumor immune status of renal cell carcinoma patient body. It can contribute to predict the prognosis of immunotherapy and provide reference for the choice of renal carcinoma post-operative adjuvant immunotherapy.

Magnetic Repulsion Forces in MCCB by 3-D FEM Analysis (3D FEM해석을 통한 배선용 차단기의 전자반발력 해석)

  • Song, Jung-Chun;Ryu, Man-Jong;Kim, Yong-Gi
    • Proceedings of the KIEE Conference
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    • 2001.07b
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    • pp.711-713
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    • 2001
  • MCCB(Molded Case Circuit Breakers) is a multi-function safety device which, unlike other forms of protection, combines many protection features in a single unit. This paper is the analysis of magnetic repulsion forces with the breaking current 11.28kA, 22.5kA, 38.9kA and 45kA.

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Prognostic Value of CD44 Variant exon 6 Expression in Non-Small Cell Lung Cancer: a Meta-analysis

  • Zhao, Shuang;He, Jin-Lan;Qiu, Zhi-Xin;Chen, Nian-Yong;Luo, Zhuang;Chen, Bo-Jiang;Li, Wei-Min
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.16
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    • pp.6761-6766
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    • 2014
  • Background: CD44v6 (CD44 variant exon 6) is the chief CD44 variant isoform regulating tumor invasion, progression, and metastasis. The prognostic value of CD44v6 expression in non small cell lung cancer (NSCLC) has been evaluated in many studies, but the results have remained controversial. Thus, we performed a meta-analysis of currently available studies to investigate the prognostic value of CD44v6 expression in NSCLC patients and the relationship between the expression of CD44v6 and clinicopathological features. Materials and Methods: Two independent reviewers searched the relevant literature in Pubmed, Medline and Embase from 1946 to January 2014. Overall survival (OS) and various clinicopathological features were collected from included studies. This meta-analysis was accomplished using STATA 12.0 and Revman 5.2 software. Pooled hazard ratios (HRs) with 95% confidence intervals (95%CIs) were calculated to estimate the effects. Results: A total of 921 NSCLC patients from ten studies met the inclusion criteria. The results showed that CD44v6 high expression was a prognostic factor for poor survival (HR=1.91, 95%CI=1.12-3.26, p<0.05). With respect to clinicopathological features, CD44v6 high expression was related to histopathologic type (squamous cell carcinoma versus adenocarcinoma: OR=2.72, 95%CI=1.38-5.38, p=0.004), and lymph node metastasis (OR=3.02, 95%CI=1.93-4.72, p<0.00001). Conclusions: Our results suggested CD44v6 high expression as a poor prognostic factor for NSCLC, and CD44v6 expression is associated with lymph node metastasis and histopathologic type. Therefore, CD44v6 expression can be used as a novel prognostic marker in NSCLC cases.

Comparison Analysis of Immune Cells between CT26 Tumor Bearing Mice and Normal Mice

  • Lee, Na Kyung;Kim, Hong Sung
    • Biomedical Science Letters
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    • v.20 no.3
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    • pp.147-155
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    • 2014
  • It has well studied that immune cells are strongly related to tumor progression and tumor suppression. To identify the difference of immune cell between tumor bearing mice and normal mice, we examined systemically the immune cell of CT26 tumor bearing mice on 21 days after tumor cell administration. As previously reported, CD4+ and CD8+ T cells population of tumor bearing mice significantly decreased 38% and 30% on day 21 compared to that of normal mice, respectively. All subpopulation of CD4 and CD8+ T cell significantly decreased, except CD49b+ T cell subpopulation. But, myeloid cell population ($CD11b^{high}$ and all Gr-1+ subpopulation) of tumor bearing mice significantly increased on day 21. Especially, all subpopulation of CD11b+Gr-1+ cell of tumor bearing mice significantly increased on day 21. Also, Foxp3+$CD25^{high}$ CD4 T cell (regulatory T cells) population significantly increased on day 21. These results suggest that tumor can induce the decline of T lymphocyte and the expansion of myeloid cells and regulatory T cells, and provide the basic information for the study of tumor immunology.

Heavy Metal Uptake of Acacia from Tailing soil in Abandoned Jangun Mine, Korea (장군광산 광미 토양으로부터 아카시아의 중금속 전이에 관한 연구)

  • Jeong, Hong-Yun;Kim, Young-Hun;Kim, Jeong-Jin
    • Journal of the Mineralogical Society of Korea
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    • v.28 no.2
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    • pp.173-185
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    • 2015
  • Janggun mine (longitude $129^{\circ}$ 03'38.91" Latitude $36^{\circ}$ 51'31.59") had been operated as an underground mine for last few decades. As the part of the remediation process, the surface of tailing dump was covered with uncontaminated soil about 20 cm in depth and acacia trees were planted. Heavy metal uptake of acacia from tailing soil has continued for the past 15 years. Heavy metal concentration ranges of tailing soil that contaminated with As (66.43-9325.34 mg/kg), Cd (0.96-1.09 mg/kg), Cu (16.90-57.60 mg/kg), Pb (57.33-945.67 mg/kg), and Zn (154.48-278.61 mg/kg) have higher than those of control soil As (38.98 mg/kg), Cd (0.42 mg/kg), Cu (10.26 mg/kg), Pb (8.21 mg/kg), Zn (46.74 mg/kg). The As, Cd, Cu, Pb and Zn concentrations of leaf of acacia in highly contaminated tailing dump were 165.95, 0.04, 10.68, 3.18, 48.11 mg/kg, respectively. The metal contents of leaf of acacia tree that obtained from uncontaminated control soil are 1.31 of As, 3.90 of Cu, 0.22 of Pb and 11.01 mg/kg of Zn. It was investigated that in the acacia tree, heavy metals such as As, Cu, Pb and Zn tend to be more highly concentrated in bark and leaf, compared with sapwood and heartwood.

Studies on the Cadmium removal from Soil through crops cultivation (토양중(土壤中) 카드뮴제거(除去)를 위(爲)한 식물(植物)의 재배이용연구(栽培利用硏究))

  • Kim, Bok-Young;Kim, Kyu-Sik;Cho, Jae-Kyu
    • Korean Journal of Soil Science and Fertilizer
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    • v.22 no.2
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    • pp.111-115
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    • 1989
  • In order of remove Cd by plants cultivation in the cadimum contamination soil, six fibers, four flowering and two sapling plants were cultivated at Cd treated soil, adjusted to 15 ppm. The Cd contents of plants and absorbed Cd concentration in plant, and residual Cd in soil were analyzed. The results obtained are as follows: 1. The Cd content in marigold was the highest, 161.7ppm, 22.5 times higher than rice. The Cd contents in plants was in the order of 58.3 ppm in sedge, 58.0 ppm in coreopsis, 43.5 ppm in sunflower, 38.3 ppm in scruber, and 31.9 ppm in flax. 2. The absorbed Cd in Popuaus alba x P. glandulosa was the highest, 24.11 mg/pot, 35.5 times higher than rice. The absorbed Cd by plants were in the order of 10.86 mg/pot in italianpoplar, 9.61 mg/pot in marigold, and 9.04 mg/pot in kenaf. 3. The residual Cd contents was the lowest in Popuaus alba x P. glandulosa soil and cotton followed. 4. Absorbed Cd dontent in plants was negatively correlated with the residual Cd concentration in soil.

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Cadmium-induced COX-2 Expression in Cerebrovascular Endothelial Cells (카드뮴이 뇌혈관 내피세포에서의 $PGE^2$ 및 COX-2 발현에 미치는 영향)

  • Park Dong-Hyun;Kim Young-Chae;Moon Chang-Kiu;Jung Yi-Sook;Baik Eun-Joo;Moon Chang-Hyun;Lee Soo-Hwan
    • Environmental Analysis Health and Toxicology
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    • v.21 no.3 s.54
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    • pp.275-282
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    • 2006
  • In order to get insight into the mechanism of cadmium (Cd)-induced brain injury, we investigated the effects of Cd on the induction of COX-2 in bEnd.3 mouse brain endothelial cells. Cd induced COX-2 expression and $PGE_2$ release, which were attenuated by thiol-reducing antioxidant N-acetylcysteine (NAC) indicating oxidative components might contribute to these events. Indeed, Cd increased cellular reactive oxygen species (ROS) level and DNA binding activity of nuclear factor-kB (NF-kB), an oxidative stress sensitive transcription factor. Cd-induced $PGE_2$ production and COX-2 expression were significantly attenuated by Bay 11 7082, a specific inhibitor of NF-kB and by SB203580, a specific inhibitor of p38 mitogen activated protein kinase (MAPK). These data suggest that Cd induces COX-2 expression through activation of NF-kB and p38 MAPK, the oxidative stress-sensitive signaling molecules, in brain endothelial cells.