• 대한한방내과학회지
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• 제36권4호
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• pp.447-457
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• 2015

Objectives: This study was undertaken to investigate how Cortex Phellodendri affects metabolic functional change in an experimental rat model of obesity.Methods: An obesity model was induced in a C57BL/6 mouse with a high-fat diet. Mice were divided into three groups (n=6) of normal diet, high-fat diet (=control), and high-fat diet with Cortex Phellodendri. After 12 weeks, we measured the three mice groups’ body weight, FBG, FBI, HOMA-IR, OGTT, the weight of epididymal fat and liver, the percentage of ATM, and the gene expression of TNF-α, IL-10, and CD68.Results: Cortex Phellodendri significantly reduced blood glucose and oral glucose tolerance levels. It also reduced ATM numbers and TNF-α and CD68 gene expression and increased IL-10 gene expression.Conclusions: This study suggests that Cortex Phellodendri normalized the blood glucose and reduced the expression of inflammatory markers. However, with respect to other indicators of metabolic function in obesity, there were no significant results.

• Bulletin of the Korean Chemical Society
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• 제30권10호
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• pp.2299-2302
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• 2009

By controlling the number of electrons transferred to the emitting layer, highly efficient three-wavelength WOLEDs were fabricated. Such WOLEDs are different from those made using simple stacking of RGB emitting layers in that the movement distribution of electrons transferred to emitting layer could be adjusted using the difference in LUMO energy level and that lights of all 3 wavelengths could be emitted through appropriate arrangement of RGB emitting layers. WOLED device with the structure of m-MTDTA (40 nm)/NPB (10 nm)/ Coumarin6 doped $Alq_3$ (3%) (8 nm)/ Rubrene doped NPB (5%) (15 nm)/NPB (2 nm)/ DPVBi (20 nm)/$Alq_3$ (20 nm)/LiF (1 nm)/Al (200 nm) showed high luminance efficiency of 8.9 cd/A and color purity of (0.31, 0.40). In addition, WOLED device with the thickness of non-doped NPB layer increased from 2 nm to 3 nm to increase blue light emission showed a luminance efficiency of 7.6 cd/A and color purity of (0.28, 0.36).

• 한국환경과학회지
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• 제16권6호
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• pp.725-733
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• 2007

The contents of five heavy metals such as lead, cadmium, zinc, copper and manganese in soil and vegetables collected from four sites in Busan district with composite sampling method were determined with ICP emission spectrometer. The ranges of their contents in soil were lead, $1.65\sim4.36ppm;$ cadmium, $0.05\sim0.09ppm;$ zinc, $6.33\sim11.09ppm;$ copper, $0.44\sim1.35ppm;$ manganese, $8.40\sim19.39ppm$, respectively. These contents were lower than the Clarke number. The range of heavy metal contents in four vegetables such as lettuce, radish and its roots, spinach and cabbage were lead, $0.09\sim0.48ppm;$ cadmium, $0.01\sim0.08ppm;$ zinc, $1.81\sim14.62ppm;$ copper, $0.14\sim1.87ppm;$ manganese, $0.71\sim14.5$ 5ppm with the order of Zn(7.30 ppm)>Mn(4.35 ppm)>Cu(0.53 ppm)>Pb(0.19 ppm)>Cd(0.04 ppm) in average contents. The average transfer ratio of metals from soil to vegetables was order of Zn(77.8 %)> Cd(37.5 %)>Cu(34.5 %)>Mn(18.6 %)>Pb(6.7 %). In case of the same cultivating soil, the transfer ratio could be expected to the order of spinach$lettuce{\approx}cabbage$

• 한국정보과학회논문지:시스템및이론
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• 제36권1호
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• pp.40-51
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• 2009

그래프 G의 쌍형 다대다 k-서로소인 경로 커버(쌍형 k-DPC)는 k개의 서로 다른 소스-싱크 쌍을 연결하며 그래프에 있는 모든 정점을 지나는 k개의 서로소인 경로 집합이다. 이 논문에서는 재귀원형군 G($cd^m$,d), $d{\geq}3$과 토러스에서 서로소인 경로 커버를 고려하여, 이분 그래프가 아니고 분지수가 $\delta$인 재귀원형군과 토러스는 고장 요소(정점이나 에지)가 f개 이하일 때 $f+2k{\leq}{\delta}-1$을 만족하는 임의의 f, $k{\geq}1$에 대하여 쌍형 k-DPC를 가짐을 보인다.

• 대한한방내과학회지
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• 제36권3호
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• pp.348-360
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• 2015

Objectives From observing the tongue of a patient, one can assess the health status; this method has been frequently used in traditional Korean Medicine (KM) clinics. In particular, KM posits that the color of the tongue is highly related to digestive functions. In this study, the color of tongue and heart rate variability (HRV) were compared between chronic dyspepsia (CD) patients and healthy subjects. Methods Healthy subjects and CD patients with functional dyspepsia (FD), gastroesophageal reflux disease (GERD), or chronic gastritis (CG) were enrolled for the study. Profile view images of the tongue were acquired by using a computerized tongue image acquisition system (CTIS). The color of the tongue body was extracted from the non-coated region on the tongue images. Results Color differences in CIE L*a*b* color space between the three sub-types of CD patients and healthy subjects were analyzed by using multiple linear regression analysis with age and sex as the factors. The variable b* was significantly lower in GERD patients than in the controls (p=0.017). Variable a* was significantly lower in CG than in the controls (p=0.03). No significant difference was seen between FD and controls. In GERD, the tongue body seems to be intense red in color; in CG, pale red. Frequency domain analysis showed that HF was significantly lower in GERD patients than in the controls (p=0.041). Conclusions The color of the tongue body and HF of HRV can be used for diagnosing digestive functions in health care.

• 한국식품과학회지
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• 제36권3호
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• pp.375-378
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• 2004

우리나라에서 유통되는 꽃게, 기타게, 꽃새우, 기타새우, 닭새우, 갯가재 등 58건 갑각류에 대하여 수은 함량은 mercury analyzer로, 납, 카드뮴, 비소함량은 습식분해 후 ICP 또는 AAS로 분석한 결과, 갑각류 중 중금속 함량 최소-최대(평균), mg/kgl은 수은 0.004-28(0.06), 납 ND-0.31(0.03), 카드뮴 0.003-0.92(0.15), As 0.01-35.9(6.64)이었다. 본 연구결과는 다른나라에서 보고된 갑각류중 중금속 함량과 유사한 수준이었다. 우리나라 국민이 갑각류 섭취에 의한 수은, 납, 카드뮴의 주간섭취량 은 FAO/WHO에서 정한 잠정주간섭취허용량의 약 1% 미만인 것으로 나타났다.

• Nutrition Research and Practice
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• 제7권2호
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• pp.109-114
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• 2013

We compared the preventive capacity of high intakes of vitamin C (VC) and vitamin E (VE) on oxidative stress and liver toxicity in rats fed a low-fat ethanol diet. Thirty-two Wistar rats received the low fat (10% of total calories) Lieber-DeCarli liquid diet as follows: either ethanol alone (Alc group, 36% of total calories) or ethanol in combination with VC (Alc + VC group, 40 mg VC/100 g body weight) or VE (Alc + VE group, 0.8 mg VE/100 g body weight). Control rats were pair-fed a liquid diet with the Alc group. Ethanol administration induced a modest increase in alanine aminotransferase (ALT), aspartate aminotransferase (AST), conjugated dienes (CD), and triglycerides but decreased total radical-trapping antioxidant potential (TRAP) in plasma. VE supplementation to alcohol-fed rats restored the plasma levels of AST, CD, and TRAP to control levels. However, VC supplementation did not significantly influence plasma ALT, AST, or CD. In addition, a significant increase in plasma aminothiols such as homocysteine and cysteine was observed in the Alc group, but cysteinylglycine and glutathione (GSH) did not change by ethanol feeding. Supplementing alcohol-fed rats with VC increased plasma GSH and hepatic S-adenosylmethionine, but plasma levels of aminothiols, except GSH, were not influenced by either VC or VE supplementation in ethanol-fed rats. These results indicate that a low-fat ethanol diet induces oxidative stress and consequent liver toxicity similar to a high-fat ethanol diet and that VE supplementation has a protective effect on ethanol-induced oxidative stress and liver toxicity.

• 대한화학회지
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• 제36권5호
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• pp.652-660
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• 1992

폴리아민 리간드인 diethylenetriamine(dien), triethylenetetramine(trien), tetraethylenepentamine(tetren), 및 pentaethylenehexamine(penten)을 Chloromethylated Polystyrene $({\circledP}-) 수지에 반응시켜 각기 {\circledP}_L-Dien, {\circledP}_L-Trien, {\circledP}_L-Tetren 및 {\circledP}_L-Penten 수지를 합성한 후 Bjerrum법으로 pH를 측정하여 산해리상수 및 금속과의 안정도상수를 결정하였으며, Van't Hoff 식에 의해 {\Delta}H와 {\Delta}G도 구하였다. 이들 수지의 안정도상수(log k1)는 금속이온의 종류에 따라 Cu(Ⅱ) > Ni(Ⅱ) > Cd(Ⅱ) > Zn(Ⅱ) > Co(Ⅱ)의 순으로 감소하였으며, 수지중 주게 원자인 질소수가 증가함에 따라 {\circledP}_L-Dien < {\circledP}_L-Trien < {\circledP}_L-Tetren < {\circledP}_L-Penten의 순으로 증가하였다. 그리고 pH 변화에 대한 금속이온의 흡착량 및 분리도를 시험해 본 결과 이들 금속이온과의 안정도 상수값의 순서와 일치하였다.

• 한국환경과학회지
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• 제7권5호
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• pp.623-631
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• 1998

Pyrite contained in wasted ore dumps induces a strong acid environment when it contacts oxygenated rainfall. Present research was designed to evaluate the pollution of an area that is supposedly contaminated by pyrite of ore wasted dumps form in Chonju Il Mine. Measured are the pH and selected heavy metal elements in the supposedly polluted hydrologic system. The samples include three types : those collected from the stream waters; those from the stream sediments; and those from the rice field soil scattered over the area. The dispersion path of the pollution source was also traced. The pH of the hydrologic system ranged from 3.44 to 5.46, which clearly indicates that the area is on the acid environment. The pH tends to rise as the distance from the minehead increases. The content of heavy metal elements dissolved in the stream water varies as follows; Mn=69.73~1.99ppm, Cd=0.02~0.03ppm, Zn=0.77~1.18ppm, Cu=0.04~0.13ppm, Pb=0.22~0.32ppm. The stream water in this state may induce serious heavy metal pollution to the agricultural land and the water for human life especially in the villages down the stream. The content of heavy metal elements dissolved in the stream sediment varies as follows; Mn=245.0~4685.0ppm, Cd=10.0~15.0ppm, Zn=105.0~210.0ppm, Cu=65.0~155.0ppm, Pb=90.0~150.0ppm. The content of heavy metal elements dissolved in the rice field soil varies as follows; Mn=185.0~260.0ppm, Cd=10.0~15.0ppm, Zn=135.0~180.0ppm, Cu=65.0~90.0ppm, Pb=100.0~130.0ppm. The pollution index in the stream sediment and the rice field sell is 1.36~2.03, which shows that pollution had already begun all over the area where the samples were collected.

• Ocean and Polar Research
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• 제25권4호
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• pp.447-457
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• 2003

In order to understand the distribution of changes of geochemical characteristics in surface sediments according to various environmental changes around the artificial Lake Shihwa, surface sediments were sampled at $13{\sim}15$ sites form 1997 to 1999 and analyzed by C/S analyzer, ICP/MS and AAS. The average $S/C_{org}$ ratio was 0.35 in the surface sediments, which is similar to 0.36, the characteristic ratio of marine sediments. Heavy metal contents and enrichment factors in the surface sediments tended to be decreasing from the head to the mouth of the Lake Shihwa. With the deposition of fine-grained sediments in the central part of lake, anoxic water column induced the sulfides compounds with Cu, Cd and Zn. Metals such as Al, Fe, Cr, Co, Ni, Cu, Zn and Cd except for Mn and Pb showed relatively high correlation coefficients among them. The contents of Cr, Co, Ni, Cu, Zn and Cd in the surface sediments of the lake were two to five times higher than those in the lake before dike construction and also in outer part of the dike. These are mainly due to the Input of untreated industrial and municipal waste-waters into the lake, and the accumulation of heavy metals by limitation of physical mixing. Although metal contents of the surface sediments at the sites near the water-gate due to outer seawater inflow tended to be lower than those during the desalination, heavy metals were deposited in areas around the new industrial complex in the evidence of spatial distribution of heavy metals in the sediments. This is mainly due to the input of untreated waste-waters from tributaries.