• 제목/요약/키워드: CD27

검색결과 571건 처리시간 0.024초

한국산 녹차, 우롱차 및 홍차가 카드뮴에 중독된 흰쥐 간조직의 항산화적 해독작용에 미치는 영향 (Effects of Korean Green Tea, Oolong Tea and Black Tea Beverage on the Antioxidative Detoxification in Rat Poisoned with Cadmium)

  • 윤연희
    • Journal of Nutrition and Health
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    • 제27권10호
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    • pp.1007-1017
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    • 1994
  • In order to investigate the effect of Korean green tea, oolong tea and black tea beverage on the antioxidative detoxification in cadmium(Cd) poisoned rat liver, male Sprague-Dawley rat weighing 143$\pm$3.2g were divided into control and experimental groups. The experimental groups were fed standard diet containing 40ppm Cd and were given distilled water(CD), 5% black tea(BT), oolong tea(OT) and green tea(GT), respectively. Tea beverages were extracted from 5G dry leaves of teas in 100ml hot distilled water by the treatment at 85$^{\circ}C$ for 3 min. Liver xanthine oxidase(XOD) activity was increased by the administration of Cd except GT group. Liver superoxide dismutase(SOD), glutathione peroxidase(GSH-px), glutathione S-transferase(GST) activities were decreased by te administration of Cd but did not decreased by the administration of green tea(in GT group). Vitamin E and reduced glutathione contents were significantly decreased in Cd administered groups. Liver lipid peroxide value in Cd administered groups were increased compared to control group, but was not increased in GT group. Serum glutamic oxaloacetic transaminase(GOT) activities in CD, OT, BT groups were higher than control, but that in GT group was similar to control group. Serum glutamic pyruvic transaminase(GPT) activity was not significantly different among various groups. It was concluded that green tea might alleviate peroxidative damage in Cd-administered rat liver by reinforcing antioxidative detoxification system.

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우리나라 토양의 중금속 배경농도 및 특성 조사

  • 김동호;김태승;윤정기;전성환;정일록;김종하
    • 한국지하수토양환경학회:학술대회논문집
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    • 한국지하수토양환경학회 2005년도 총회 및 춘계학술발표회
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    • pp.6-8
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    • 2005
  • The forest soils of 92 sites in Korea were analyzed to survey heavy metal background levels using aqua regia digestion method and 0.1N HCl extraction method. From these results, the average natural contents of heavy metals were Cd 0.287, Cu 15.26, Pb 18.43, Cr 25.36, Zn 54.27, Ni 17.68mg/kg for aqua regia method, and Cd 0.040, Cu 0.48, Pb 3.06, Cr 0.09, Zn 1.54, Ni 0.27mg/kg for 0.1N HCl extraction method. The range of correlation coefficients between heavy metal contents obtained from two methods(aqua regia and 0.1N HCl) was significant as $0.24{\sim}0.88$, and the correlation coefficients were decreased in order of Cd, Pb, Cu, Ni, Cr, Zn.

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황기건중탕(黃芪建中湯)이 Methotrexate로 유도된 흰쥐의 면역기능저하(免疫機能低下)에 미치는 영향(影響) (The Effect of Hwanggigunjung-tang on Imunosuppression induced by Methotrexate in Rat)

  • 백정한;구진숙
    • 대한한방소아과학회지
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    • 제18권1호
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    • pp.27-48
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    • 2004
  • Objective: The purpose of this study was to investigate the effect of Hwanggigunjungtang(HGT) on white rats with deteriorated immunity caused by methotrexate. Methods: First, methotrexate was fed to the white rats once a day for 4 days. After the immune responses of the rats are deteriorated, dried extracts of HGT mixed in water was fed to the rats once a day for 14 days. And then we measured the percentage of B-cell and T-cell in peripheral blood, the percentage of CD3+CD4+ T-cell and CD3+CD8+ T-cell of blood sampled from spleen and peripheral region. Results: The percentage of B-cell of peripheral blood was not different statistically. The percentage of T-cell of peripheral blood was increased significantly in HGT group as compared with control group. The percentage of CD3+CD4+ T-cell of peripheral blood was increased significantly in HGT group as compared with control group. The percentage of CD3+CD8+ T-cell of peripheral blood was decreased in HGT group as compared with control group. The percentage of CD3+CD4+ T-cell of spleen was increased significantly in HGT group as compared with control group. The percentage of CD3+CD8+ T-cell of spleen was not different statistically. Conclusion: According to the above results, HGT has an effect of increasing immune responses on white rats with deteriorated immunity caused by methotrexate.

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Hot Wall epitaxy(HWE)법에 의한 $CdGa_2Se_4$ 단결정 박막의 성장과 가전자대 갈라짐에 대한 광전류 연구 (Photocurrent study on the splitting of the valence band and growth of $CdGa_2Se_4$ single crystal thin film by hot wall epitaxy)

  • 박창선;홍광준
    • 한국결정성장학회지
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    • 제17권5호
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    • pp.179-186
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    • 2007
  • [ $CdGa_2Se_4$ ] 단결정 박막을 수평 전기로에서 합성한 $CdGa_2Se_4$ 다결정을 증발원으로하여, hot wall epitaxy(HWE) 방법으로 증발원과 기판(반절연성-GaAs(100))의 온도를 각각 $630^{\circ}C,\;420^{\circ}C$로 고정하여 성장하였다. 이때 단결정 박막의 결정성은 광발광 스펙트럼과 이중결정 X-선 요동곡선(DCRC)으로 부터 구하였다. Hall 효과는 van der Pauw 방법에 의해 측정되었으며, 293K에서 운반자 농도와 이동도는 각각 $8.27{\times}10^{17}cm^{-3},\;345cm^2/V{\cdot}s$였다. $CdGa_2Se_4/SI$(Semi-Insulated) GaAs(100) 단결정 박막의 광흡수와 광전류 spectra를 293K에서 10K까지 측정하였다. 광흡수 스펙트럼으로부터 band gap $E_g(T)$는 Varshni 공식에 따라 계산한 결과 $E_g(T)=2.6400eV-(7.721{\times}10^{-4}eV/K)T^2/(T+399K)$였다. 광전류 스펙트럼으로부터 Hamilton matrix(Hopfield quasicubic mode)법으로 계산한 결과 crystal field splitting 에너지 ${\Delta}cr$값이 106.5meV이며 spinorbit 에너지 ${\Delta}so$값은 418.9meV임을 확인하였다. 10K일 때 광전류 세 봉우리들은 $A_{1^-},\;B_{1^-}$$C_{11}-exciton$ 봉우리임을 알았다.

Cyclodextrin의 사용과 pH의 변화를 이용한 Levofloxacin 생산 증대 연구

  • 문지숙;노윤숙;오선영;장성재;임상민;김동일
    • 한국생물공학회:학술대회논문집
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    • 한국생물공학회 2001년도 추계학술발표대회
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    • pp.662-665
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    • 2001
  • PLE를 이용한 levofloxacin의 생산에서 기질 150 mM 사용의 경우 두배의 몰농도 로 ${\alpha}-CD$를 사용하여 산물의 생산량을 3.7 배까지 증가시킬 수 있었다. 그러나 이 경우 ${\alpha}-CD$의 사용량이 많아 경제성이 떨어지는 단점이 있다. 이에 같은 몰농도로 ${\alpha}-CD$를 사용하고 pH에 변화를 주어 용해도를 향상시켜 보았다. 기질 100 mM의 경우 pH 5.6에서 같은 몰농도의 ${\alpha}-CD$를 사용한 경우 ${\alpha}-CD$를 사용하지 않은 것에 비해 4.4배의 수율의 증대가 있었다.

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Crosslinking of $\beta$-Cyclodextrin on Cholesterol Removal from Milk

  • Kim, S.H.;Ahn, J.;Kwak, H.S.
    • Archives of Pharmacal Research
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    • 제27권11호
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    • pp.1183-1187
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    • 2004
  • This study was designed to develop crosslinking of $\beta$-cyclodextrin ($\beta$-CD), and determine the optimum conditions of different factors (mixing time, mixing temperature, and mixing speed) on cholesterol reduction from milk. Crosslinked $\beta$-CD was prepared with epichlorohydrin. When milk was treated with different conditions, the cholesterol removal rate was in the range of 79.4 to 83.3% with 1 % crosslinked $\beta$-CD addition, which were not significantly different among treatments. After cholesterol removal from milk, the used crosslinked $\beta$-CD was washed for cholesterol dissociation and reused. For recycling study, the cholesterol removal rate in first trial was 81.8%, which was mostly same as that using new crosslinked $\beta$-CD. With five trials repeatedly using the same sample, the mean cholesterol removal rate was 81.2%. The present study indicated that the optimum conditions on cholesterol removal using crosslinked $\beta$-CD were 10 min mixing with 400 rpm speed at $5^{\circ}C$ with about 80% cholesterol removal. In addition, crosslinked $\beta$-CD resulted in the effective recycling efficiency almost 100%.

Fluorescent Blue Materials for Efficient Organic Light-Emitting Diode with High Color Purity

  • Choi, Kyung-Sun;Lee, Chan-Hyo;Lee, Kwan-Hee;Park, Su-Jin;Son, Seung-Uk;Chung, Young-Keun;Hong, Jong-In
    • Bulletin of the Korean Chemical Society
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    • 제27권10호
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    • pp.1549-1552
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    • 2006
  • We report a new series of blue dopants composed of both electron donating and electron accepting moieties in one molecule, based on nalidixic acid. The EL device derived from the dopant exhibits pure blue light emission (0.15, 0.14) The current efficiency is estimated to be 3.88 cd/A at 100 $cd/m^2$, which shows remarkable enhancement, compared to that of the host itself (2.5 cd/A at 100 $cd/m^2$) under the same conditions. These results demonstrate that the incorporation of a proper guest into the host in a guest-host doped system improves not only the purity of the fluorescent blue emission but also elevates its quantum efficiency, thus improving the OLED performance.

우리나라 토양중 토지용도 및 시험방법별 중금속 분포 특성

  • 김태승;김동호;윤정기;박종겸;정일록;김종하;김혁
    • 한국지하수토양환경학회:학술대회논문집
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    • 한국지하수토양환경학회 2006년도 총회 및 춘계학술발표회
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    • pp.242-246
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    • 2006
  • Background level of heavy metals In soils (316 points by 15 classifications of land use) was investigated by two test methods, 0.1N HCl(1N HCl for As) extraction and aqua regia extraction methods. The average concentrations of aqua regia extractable heavy metals in soil(n=316) was 6.24(As), 0.25(Cd), 37.99(Cr), 24.10(Cu), 0.04(Hg), 25.68(Pb), 22.59(Ni), 106.11(Zn) mg/kg, respectively. Also the average concentrations of 0.1N HCl extractable heavy metals was 0.06(As), 0.08(Cd), 0.27(Cr), 3.78(Cu), 4.02(Pb), 12.5(Zn), 0.58(Ni) mg/kg, respectively. The ratio of soluble contents and total contents were 2.6%(As), 32.7%(Cd), 0.7%(Cr), 15.7%(Cu), 15.7%(Pb), 2.6%(Ni), 11.8%(Zn), and the correlation coefficient of soluble contents and total contents were 0.26(As), 0.27(Cd), 0.22(Cr), 0.57(Cu), 0.42(Pb), 0.23(Ni), 0.72(Zn).

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RS485 기반 다수 노드 제어용 저속통신망에서의 CSMA/CD 기법 적용 및 성능 개선 방안 (Performance Analysis and Improvement of RS485 Based Low Speed and Multi-Node CSMA/CD for Control Network System)

  • 김민기;최용우;박동찬;김석찬
    • 한국산업정보학회논문지
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    • 제20권1호
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    • pp.27-35
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    • 2015
  • 본 논문에서는 저속이지만 다수 노드의 연결이 요구되는 산업용 제어통신망, 홈네트워크 등에서 널리 사용되는 RS485에 적용할 수 있는 CSMA/CD 기법을 제안하고, 기존의 Master-Slave 프로토콜인 Modbus와 성능을 비교하였다. 모의실험을 위해 실제 산업용 제어통신망을 모델링 하였고, 모의실험을 통하여 여러 전송속도에서 평균 전송 지연시간과 처리량이 크게 개선됨을 보였다.

Chitin과 Chitosan이 흰쥐의 Cadmium중독과 지방대사에 미치는 영향 (Effect of Dietary Chitin and Chitosan on Cadmium Toxicity and Lipid Metabolism in Rats)

  • 김미경
    • Journal of Nutrition and Health
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    • 제27권10호
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    • pp.996-1006
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    • 1994
  • This study was performed to investigate the effect of dietary chitin & chitosan on cadmium (Cd) toxicity and lipid metabolism in rats. Forty-two male rats of Sprague-Dawley strain weighing 137$\pm$2g were blocked into 6 groups according to body weight, and were raised for 4 weeks. Cadmium chloride was given at the level of 0 or 400ppm in diet and chitin and chitosan were given at the level of 0 or 4%(w/w) of diet. The results are summarized as follow. Chitosan decreased the toxicity of Cd on liver, kidney and femur and increase the Cd content of fecal excretion. Chitosan increased the lipdi & cholesterol content of fecal excretion by combining with lipid and bile acid. Chitosan decreased lipid, cholesterol and TG content in serum and liver by combining with lipid and bile acid. Chitin was less effective than chitosan in decreasing of Cd toxicity and lipid content of rat.

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