• 제목/요약/키워드: CD18

검색결과 794건 처리시간 0.03초

우울 및 불안장애 환자에서 리질리언스와 감사 성향의 관련성 (Associations Between Resilience and Gratitude in Patients With Depression and/or Anxiety Disorders)

  • 민정아;이원희;정영은;홍현미;채정호
    • 대한불안의학회지
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    • 제18권1호
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    • pp.26-31
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    • 2022
  • Objective : The levels of resilience and gratitude were examined in psychiatric patients with depression and/or anxiety disorders and compared to those of the general population. In addition, we analyzed the associations of positive affect, negative affect, depressive and anxiety symptoms, and gratitude on resilience in this patient population. Methods : The participants included a general population sample (n=155) and psychiatric outpatients with depression and/or anxiety disorders (n=108). All participants completed self-report questionnaires, which included demographic variables, the Connor-Davidson Resilience Scale (CD-RISC), the Gratitude Questionnaire-Six-Item Form (GQ-6), the Positive Affect Negative Affect Scale (PANAS), and the Hospital Anxiety and Depression Scale (HADS). Results : The CD-RISC and GQ-6 scores of patients with depression and/or anxiety disorders were significantly lower than those of the general population. In the patient population, hierarchical regression analysis showed that gratitude was significantly associated with resilience while controlling for a range of demographic and clinical variables. Conclusion : Patients with depression and/or anxiety disorder generally had lower resilience and gratitude. Moreover, our findings showed that gratitude could influence the levels of resilience in patients with depression and/or anxiety disorders.

목근피가 $\betaA$로 유도된 Alzheimer's Disease 생쥐 모델에 미치는 영향 (The Effects of Hibiscus Syriacus Extract on the Alzheimer's Disease Mice Model Induced by $\betaA$)

  • 이상룡;정인철
    • 동의생리병리학회지
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    • 제18권3호
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    • pp.797-807
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    • 2004
  • This research investigates the effect of the Hibiscus syriacus(HSS) on Alzheimer's disease. The effects of the HSS extract on the behavior in the Morris water maze experiment; the expression of IL-1β, TNF-α, IL-1β mRNA, TNF-α mRNA, CD68/GFAP and RDS; the the infarction area of the hippocampus, and brain tissue injury in Alzheimer's diseased mice induced with M were investigated. The HSS extract group showed a significant inhibitory effect on the memory deficit on the mice with Alzheimer's disease induced by βA in the Morris water maze experiment. The HSS extract group suppressed the over-expression of IL-1β, TNF-α, IL-1β and TNF-α mRNA, CD68/GFAP, RDS in the mice with Alzheimer's disease induced by βA. The HSS extract reduced the infarction area of hippocampus, and controlled the injury of brain tissue in the mice with Alzheimer's disease induced by βA. This study suggest that HSS may be effective for the prevention and treatment of Alzheimer's disease

안모비대칭환자의 임상적 특성 및 악교정수술후 변화에 관한 연구;정모두부방사선 규격사진의 계측을 중심으로 (POSTEROANTERIOR CEPHALOMETRIC STUDY OF FACIAL ASYMMETRY ABOUT CLINICAL CHARACTERISTICS AND CHANGES AFTER ORTHOGNATHIC SURGERY)

  • 최유성;이상철
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제18권3호
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    • pp.396-410
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    • 1996
  • This study was carried out to evaluate the distribution and the degree of the asymmetry existed in normal persons and asymmetric patients, and to investigate the changes of asymmetric patients after orthognathic surgery. The analysis was performed with the posteroanterior cephalometric radiography of 60 normal persons and 31 facial asymmetric patients. The results were as follows : 1. The degree of normal asymmetry existed in normal persons was not significant except MF and Me measurements. 2. The degree of normal asymmetry according to sex difference was not significant except cranial base area. 3. When normal persons were compared to asymmetric patients, there were more measurements which presented significant asymmetry on mandible than on maxilla. 4. When postoperative state was compared to preoperative state, the degree of asymmetry were usually decreased except AGO and GA measurements, especially the Cd, MF, Me, and Cd-Me measurements decreased significantly. 5. When postoperative state was compared to normal persons, 4 measurements of mandible approached significantly the measurements of normal persons.

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목과의 $\betaA$로 유도된 Alzheimer's Disease 생쥐 모델에 미치는 영향 (Effects of Chaenomelis Fructus Extract on the Alzheimer's Disease Mice Model Induced by $\betaA$)

  • 정인철;이상룡
    • 동의생리병리학회지
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    • 제18권6호
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    • pp.1795-1804
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    • 2004
  • This research investigated the effect of the Chaenomelis fructus(CMF) on Alzheimer's disease. The effects of the CMF extract on the behavior in the Morris water maze experiment; the expression of IL-1β, TNF-α, ROS on the microglial cell; IL-1β mRNA, TNF-α mRNA, CD68/GFAP and MDA on the brain tissue; the infarction area of the hippocampus, and brain tissue injury in the mice with Alzheimer's disease induced by βA were investigated. The CMF extract group showed a significant inhibitory effect on the memory deficit on the mice with Alzheimer's disease induced by βA in the Morris water maze experiment. The CMF extract group suppressed the over-expression of IL-1β, TNF-α, IL-1β and TNF-α mRNA, ROS, MDA, CD68/GFAP in the mice with Alzheimer's disease induced by βA. The CMF extract reduced the infarction area of hippocampus, and controlled the injury of brain tissue in the mice with Alzheimer's disease induced by [3A. This study suggest that CMF may be effective for the prevention and treatment of Alzheimer's disease.

중금속에 의한 토양오염과 그 작물함량에 관한 연구 (A Study on the heavy metal contents in the soils and vegetables)

  • 김명미;고영수
    • 한국식품위생안전성학회지
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    • 제1권1호
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    • pp.51-56
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    • 1986
  • In the particular area the heavy metal concentrations in the soil were determined and compared to the contents in vegetables which were grown on the soil. Simultaneously the degree of contamination was examined. Samples were collected from Chinese cabbage, radish and Altari-mu, together with the soil on which the three kinds of vegetables have grown. The sites of samples collection were Jinguan-sa(non-polluted area) and Sangaedong(polluted area). The contents of cadimium, copper, lead and zinc were determined by means of atomic absorption spectro-photometer. The results obtained were as follows; 1. In soils, the average contents of heavy metal in Jinguan-sa area (Cd; 0.15ppm, Cu; 0.15ppm, Zn; 11.5ppm) were lower than those in sangye-dong(Cd; 0.26ppm, Cu; 13.0ppm, Zn; 17.1ppm). 2. In vegetables, the average have metal contents in Jinguan-sa were cadmium; 0.11ppm, copper; 5.29ppm, zinc; 18.75ppm and the average contents in Sangye-dong were cadmium; 0.16ppm, copper; 6.64ppm, lead; 0.14ppm, zinc; 15.01ppm. 3. The contents of lead showed zero ppm in Jinguan-sa area(soil and vegetables). In vegetables difference in concentration of heavy metals was not observed between reclaimed area and non reclaimed area. Statistical analysis showed that no correlation in the heavy metal concentrations between those in soils and in vegetables.

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A Survey on the Heavy Metal Contents of Water and Rice in the Jeon-buk Area of Korea

  • Kim, Jong-Gyu;Lee, In-kyu
    • 한국환경보건학회:학술대회논문집
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    • 한국환경보건학회 2005년도 국제학술대회
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    • pp.323-325
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    • 2005
  • This study was performed to investigate the levels of cadmium (Cd), copper (Cu), lead (Pb), and zinc (Zn) in water and rice samples taken from five sites on a stream used for agricultural water in the Jeon-buk area, Korea. The water samples were collected by the recommendation methods of the World Health Organization, and rice samples were randomly selected from the paddy rice. The water and rice samples were analyzed by the recommendation methods of Food Code of Korea and using ICP. Although there was variation between sampling sites, the levels of the metals of rice were on average much higher than those of water. The ratios of metal levels of rice to water were: Cd 8.0${\sim}$35.4; Cu 2.2${\sim}$7.2; Pb 5.9${\sim}$18.3; and Zn 10.6${\sim}$75,7. These results indicate that there was transfer of the metals from the water to the rice, This study also suggests that there might be another pathways for the transfer of the metals to the rice.

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낙동강, 서낙동강, 수영천 하구의 하상구조에 따른 연중 퇴적저토의 오염특성 연구와 부산근해 적조에의 영향에 관한 연구 (A Study on the Relation between Riverbed Structure and Pollutant Concentration in Down Stream of Nakdong River)

  • 황선출;이봉헌
    • 한국환경과학회지
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    • 제6권5호
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    • pp.513-520
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    • 1997
  • This study was performed to investigate the riverbed structure and the pollution type in Nakdong River, Western Nakdong River. and Suyoung Stream. Sediment and water samples were collected at is in Nakdong River. in Western Nakdong River, and 8 states In Suyoung Stream from February 20, 1997 to June 15, 1997. The depth distributions of sampling sites in the three streams were measured and heavy metals(Cd, Pb, Cr, Cu) and pesticides in sediments and COD, BOD, and total nitrogen(T-N) in water samples were analysed. The deepest and the shallowest sites were strate 11(11.58m) and 9(3.35m) in Nakdong River, site 7(6.25m) and 4(2.06m) in Western Nakdong River, and site 8(2.89m) and 1(0. 61m) in Suyoung Stream , respectively. The mean concentration of Cd(45.79ppm) was higher In the sediment of Western Nakdong River than In other two streams and those of Pb(76.25ppm), Cr(48.13ppm), and Cu(77.50ppm) were higher in file sediment of Suyoung Stream than in other two streams. Pesticides(1 kind of organophosphorus and 3 kinds of organochlorine pesticide) were detected only in the sediment of Western Nakdong River. The mean concentrations of COD(20.26ppm), BOD(25.36ppm), and T-N(18.05ppm) were higher in the water sample of Suyoung Stream than In other two streams.

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Differential Activation of T Cells by T-Cell Receptor Ligand Analogs

  • Choi, Yun-Hi;Suh, Yu-Jin;Kim, Kil-Hyoun
    • BMB Reports
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    • 제30권6호
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    • pp.415-420
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    • 1997
  • Although $CD4^+$ T cell responses to protein-derived antigen have well been understood, the epitopes recognized by hapten-specific $CD4^+$ T cells have not been fully defined. In this study, we characterized the response of a T cell hybridoma (5Di0.1B8) which is specific for a hapten. N-hydroxysuccinimidyl-4-azidobenzoate (HSAB) restricted by MHC class II $I-A^d$. Using three different antigen presenting cells (APCs) expressing $I-A^d$, the role of class II MHC proteins in haptenic antigen presentation and subsequent activation of 5D10.1B8 has been examined. Activation of 5D10.1B8 T cells by HSAB analogs was also performed. Our results show that each APC activated T cells differentially and that interleukin-2 (IL-2) augmented antigen-presenting ability of all the APCs, suggesting that increased expression of class II MHC protein by IL-2 played an important role in HSAB presentation and T cell activation. Finally, early T cell receptor-dependent signals induced by HSAB or its analogs were examined by phosphotyrosine immunoblot analysis, and showed that tyrosine phosphorylation level of a 18-20 kD protein increased upon stimulation.

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동시진공증발법을 이용한 고효율 CIGS 박막 태양전지 개발 (Development of High Efficiency CIGS Thin Film Solar Cells by co-evaporation process)

  • 윤재호;안세진;안병태;박희선;윤경훈
    • 한국신재생에너지학회:학술대회논문집
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    • 한국신재생에너지학회 2009년도 춘계학술대회 논문집
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    • pp.23-23
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    • 2009
  • CIGS 박막 태양전지는 제조단가가 낮고 박막 태양전지 중에서 변환효율이 가장 높아 발전 가능성이 큰 태양전지로 인식되고 있다. 이미 일본, 독일, 미국을 비롯한 선진국에서는 30-50 MW 급의 양산 라인이 구축되고 있어 2010년 이후에는 본격적인 상용화가 진행될 것으로 보인다. CIGS 광흡수층은 진공증발, 셀렌화, 나노입자, 전기도금등 다양한 방식으로 제조가 가능한데 이 중에서도 동시진공증발공정은 고효율 CIGS 박막 태양전지 제조에 적합하다. 본 연구에서는 동시진공증발법을 이용하여 CIGS 박막을 증착하였으며 소다회유리/Mo/CIGS/CdS/i-ZnO/n-ZnO/Al/AR 구조의 태양전지를 제조하였다. 기판온도 모니터링을 통한 Cu 이차상 조절 기술을 이용하여 결정립이 매우 큰 CIGS 박막을 증착하였으며 Ga/(In+Ga) 조성비의 조절을 통하여 밴드갭 에너지를 최적화하였다. 또한 QCM 장치를 활용하여 용액 속에서 성장되는 CdS 박막의 두께와 특성을 조절하였다. 이러한 공정최적화를 통하여 개방전압 0.65 V, 단락전류밀도 38.8 $mA/cm^2$, 충실도 0.74 그리고 변환효율 18.8% 의 CIGS 박막 태양전지를 얻었다.

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금왕 금·은광산 주변 지구화학적 환경에서의 중금속 원소들의 분산 (Dispersion of Heavy Metals in the Geochemical Environment around the Geumwang Gold-Silver Mine)

  • 박종진;김명균;전효택
    • 자원환경지질
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    • 제30권5호
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    • pp.407-416
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    • 1997
  • Soil, tailings, stream sediment and surface water samples collected in the vicinity of the Geumwang Au-Ag mine were analyzed in order to investigate the pollution level of heavy metals and to determine the dispersion patterns. Although the maximum concentrations of soils collected at the flotation plant and tailings dam were 9,270 ppm As, 17 ppm Cd, 1,480 ppm Cu, 10,080 ppm Pb and 18,400 ppm Zn, dispersion of heavy metals were limited in the vicinity of the flotation plant and tailings dam. This may be due to high pH values (> 8.0) of the soils by flotation solution for mineral processing. The pH values of water samples near the flotation plant and tailings dam were over 8.0 and Cd, Cu and Zn concentrations were not detected. The waters in the vicinity of Geumwang mine generally belong to a $Ca^{2+}-SO_{4}{^{2-}}$ $(HCO_3{^-})$ type.

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