• 제목/요약/키워드: CCI4

검색결과 139건 처리시간 0.027초

Sulfonated Polyetherimide 합성 및 특성 (Synthesis and Characterization of Sulfonated Polyetherimide)

  • 김완주;최남석;최중구;김인철;김종호;탁태문
    • 멤브레인
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    • 제9권1호
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    • pp.10-16
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    • 1999
  • 본 연구에서는 pellet 상태의 polyetherimide (PEI)를 carbon tetrachloride(CCl4)와 1 ,2-dichloro-ethane (DCE) 의 부피비 5:1 하에서 PEI를 불균일한 상태로 유지시키고, chlorosulfonic acid (CSA)를 이용하여 PEI의 표면을 sulfonation 시킴으로써 , 음이온성을 띠며 친수성이 향상된 sulfonated polyetherimide (SPEI)를 제조하였다. 불균일한 상태가 유지되면서 가장 적합한 sulfonation 반응조건은 PEI: CSA 의 1 : 1 mole ratio, 온도 $10^{\circ}$, 3 시간이었다. 이온교환용량이 0.2~1.2meq/g을 갖는 SPEI를 합성할 수 있었고, FT-IR 측정을 통하여 sulfonic acid peak가 1020$cm^{-1}$ 와 1170$cm^{-1}$부근에서 관찰되었다. 분자량 분포는 sulfonation을 시킴으로써 좀 더 넓게 나타났고, 접촉각 측정을 통하여 친수성이 향상되었음을 확인하였다.

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카르보닐 신축진동 파수에 대한 용매 및 농도 효과: 디알킬 케톤 (Solvent and Concentration Effects on Carbonyl Stretching Frequencies: Dialkyl Ketones)

  • 정영미;강재수;남상일;이무상
    • 대한화학회지
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    • 제40권6호
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    • pp.415-419
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    • 1996
  • 수소결합, 유전효과 그리고 입체효과는 케톤의 카르보닐 신축진동을 결정하는 요인이 된다. 케톤의 카르보닐 신축진동은 다양한 용매에서 케톤의 농도변화에 영향을 받는다. 비극성용매에서 카르보닐 신축진동은 케톤의 부피%가 증가함에 따라 낮은 파수로 이동하고 극성용매에서는 높은 파수로 이동한다. 용매 아세토니트릴에서 카르보닐 신축진동은 dimethyl ketone을 제외하고 케톤의 부피%가 증가함에 따라 높은 파수로 이동한다. 용매의 극성이 증가할수록 카르보닐 신축진동은 낮은 파수로 이동하고 혼합용매 $CHCI_3CCI_4$에서 부피%가 증가할수록 낮은 파수로 이동한다.

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Ameliorative Potential of Rengyolone Against CCI-induced Neuropathic Pain in Rats

  • Lee, Gil-Hyun;Hyun, Kyung-Yae
    • 대한의생명과학회지
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    • 제26권4호
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    • pp.310-318
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    • 2020
  • The sciatic nerve is the largest nerve among the peripheral nerves, and the damage to the sciatic nerve is caused by mechanical and physical pressure. This is an important disease that consumes a lot of time and money in the treatment process. Among them, research on relieving nerve pain caused by damage to the peripheral sciatic nerve has been made efforts to prevent and treat this disease through various methods such as drugs, natural products, electrical stimulation, exercise therapy, and massage. Existing treatments are not very effective in neurological pain, and countermeasures are needed. Forsythia Fructus, used in this study, has been used as a therapeutic agent for infectious diseases and a pain reliever for cancer from the past, and in past studies, it has been known to properly control the inflammatory response. In this study, rengyolone, a physiologically active substance of Forsythiae Fructus, was administered to rats that caused chronic left nerve pain to verify the pain relief effect. As a result of the experiment, it was found that mechanical pain and cold stimulation pain were significantly reduced in the rengyolone-treated group compared to the non-administered group. In addition, it was found that nerve growth factor (NGF) mRNA expression was significantly reduced and Cyclin-dependent kinase 2 (Cdc2) expression was increased in the rengyolone administration group. This increase in NGF expression is thought to be related to rengyolone's anti-inflammatory regulatory mechanism. It is expected that the reduced NGF was directly involved in pain relief.

국내 500대 기업의 산림분야 사회공헌활동 프로그램의 유형과 추진방식 (The Types and Processes of Corporate Philanthropy Programs on Forestry in Korea 500 Companies)

  • 김재현;장주연;태유리;김해창
    • 한국산림과학회지
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    • 제99권6호
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    • pp.816-826
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    • 2010
  • 본 연구는 대한상공회의소에 등록되어 있는 매출액 기준 상위 500대 기업을 대상으로 산림분야 사회공헌활동의 현황과 참여유형 및 추진방식을 조사 분석한 것이다. 분석 결과 국내 500대 기업 중 75개 기업(15.0%)이 산림분야 사회공헌활동을 추진하고 있었으며, 75개 기업이 시행하고 있는 108개의 산림분야 사회공헌활동 프로그램을 유형별로 분석한 결과 자원봉사형(55.6%)과 숲조성 관리형(29.6%)이 가장 많은 비중을 차지하였다. 프로그램 추진 방식은 각 유형별로 차이를 나타내고 있는데 "자원봉사형"과 "1회성 나무심기"의 경우, 기업 내 자원봉사조직을 중심으로 한 직접사업방식이 많은 반면, "숲조성 및 관리활동"과 "교육활동" 분야에서는 지자체, 정부기관, 비영리단체 등의 파트너십을 통한 공동사업방식을 주로 취하고 있는 것으로 나타났다. 현금기부에 의한 1회성 나무심기 헌수 활동보다 임직원들의 직접적인 참여를 통한 정기적인 자원봉사형이 많이 나타나고 있고, 기업의 사회공헌팀과 정부, 지자체, 시민단체 등 다양한 주체들간의 파트너십을 통한 도시림 및 생활림 조성이 증가하고 있는 것으로 나타났다. 이를 종합해 볼 때, 국내 기업의 산림분야 사회공헌활동은 전략적 사회공헌활동 단계에 있으며, 이는 향후 교육활동형, 인재양성 및 일자리 창출형과 함께 지역사회투자활동(Corporate community investment)으로서 발전할 수 있는 가능성을 보여주고 있다.

마이크로 셀룰러 시스템에서 MRC 다이버시티와 Reed-Solomon 부호를 적용한 Trellis Coded QPSK 신호의 오율 해석 (Error Performance Analysis of Trellis Coded QPSK Signal with Reed-Solomon Coding and MRC Diversity Reception in Micro-Cellular System)

  • 노재성;김영철;박기식;조성언;조성준
    • 한국전자파학회논문지
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    • 제9권4호
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    • pp.427-438
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    • 1998
  • 본 논문에서는 동일채널간섭과 라이시안 페이딩 환경에서 Trellis Coded QPSK 시스템의 BER 생능올 분석 하였다. 고려되는 Trellis Coded QPSK 시스템은 시스템의 성능을 향상시키기 위하여 최대비 합성(MRC) 다이버시티 수신법과 Reed-Solomon 부호를 사용하였다. 유도한 오율식을 이용하여 Trellis 부호화된 QPSK 시스템의 성능을 구하여, 신호 전력 대 잡음 전력비 (SNR), 신호 전력 대 간섭파의 전력비 (SIR), 라이시안 페이딩 파라미터 (KR), MRC 다이버시티의 가지수 (M), Reed-Solomon 부호의 천체 블럭 길이 (n), Reed-Solomon 부호의 정정 가능한 심볼의 수 (t), Trellis 부호기의 상태수를 함수로 하여 그래프로 나타내고 분석하였다. 분석결과, 제안하는 시스템의 성능은 마이크로셀 환경에서 동일채널간섭과 페이딩에 의하여 영향을 받음을 알 수 있었다. 또한 희망하는 신호의 전력이나 신호 전력 대 간섭파의 전력비를 증가시켜 Trellis 부호화된 QPSK 시스템의 BER 성능을 개선할 수 있음을 알 수 있었다. 그리고 마이크로 셀룰러 시스템의 BER floor 현상은 동 일채널간섭에 의하여 발생하고, 이 현상은 신호 전력 대 간섭와의 전력배가 낮은 경우에는 높은 BER에서 발생 함을 알 수 있었다. 그리고 통일채널간섭과 라이시안 페이딩의 영향올 억압하기 위해서는 M=2인 MRC 다이버 시티 수신된 Trellis Coded QPSK 시스댐보다는 t=2, n=15인 Reed-Solomon 부호롤 척용한 Trellis Coded QPSK 시스템이 효율적임을 알 수 있었다.

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홍화씨 식이가 사 염화탄소에 의한 랫트 간손상에 미치는 영향: 병리조직학적 관찰 (The Effect of Dietary Safflower Seed Supplementation on the $CCl_4$-Induced Hepatic Injury in Rats: Histopathological Observation)

  • 하태영;정원일;박상준;정규식;이차수
    • 한국수의병리학회지
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    • 제5권1호
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    • pp.9-16
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    • 2001
  • To investigate the effects of safflower seed supplementation diet on the hepatic injury of rats administered with carbon tetrachloride (CCI$_4$), histopathological changes were assessed following acute and chronic administration in rats. In acute cases, all rats in group fed with 10% safflower seed supplementation diet survived despite the administration of lethal doses of $CCl_4$. However, most rats in group fed with control diet died. The hepatic injuries of survived rats, in the histopathological findings, were mild compared to those of dead rats. In the chronic cases, livers of group 2 fed with control diet were more progressive in fatty changes and centrilobular necrosis than those of group 3 fed with 20%safflower seed diet. However, after six weeks, livers of group 2 and 3 showed severe necrosis and mild fibrosis at the same time. Group 5 fed with 10% safflower seed supplementation diet and water containing 0.05% phenobarbital sodium showed mild fatty changes and necrosis compared with group 4 fed with control diet and water containing 0.05% phenobarbital sodium at sixth week. At 8 to 10 wee71s after the administration of $CCl_4$, severe fibrosis. fatty changes and marked necrosis were observed in group 4, but hepatic injuries were less severe in group 5. The present results suggested that safflower seed has some protective effect in hepatic lesions and consequently delay the progression of hepatic fibrosis.

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Approximate estimation of soil moisture from NDVI and Land Surface Temperature over Andong region, Korea

  • Kim, Hyunji;Ryu, Jae-Hyun;Seo, Min Ji;Lee, Chang Suk;Han, Kyung-Soo
    • 대한원격탐사학회지
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    • 제30권3호
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    • pp.375-381
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    • 2014
  • Soil moisture is an essential satellite-driven variable for understanding hydrologic, pedologic and geomorphic processes. The European Space Agency (ESA) has endorsed soil moisture as one of Climate Change Initiates (CCI) and had merged multi-satellites over 30 years. The $0.25^{\circ}$ coarse resolution soil moisture satellite data showed correlations with variables of a water stress index, Temperature-Vegetation Dryness Index (TVDI), from a stepwise regression analysis. The ancillary data from TVDI, Land Surface Temperature (LST) and Normalized Difference Vegetation Index (NDVI) from MODIS were inputted to a multi-regression analysis for estimating the surface soil moisture. The estimated soil moisture was validated with in-situ soil moisture data from April, 2012 to March, 2013 at Andong observation sites in South Korea. The soil moisture estimated using satellite-based LST and NDVI showed a good agreement with the observed ground data that this approach is plausible to define spatial distribution of surface soil moisture.

Effects of the Low Power He-Ne IR Laser Treatment on the Liver Damage Induced with $CCI_4$ in Rats

  • Rho Min-Hee;Kim Jai-Young
    • 대한의생명과학회지
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    • 제10권3호
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    • pp.231-235
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    • 2004
  • This study was investigated the effects of the lower power He-Ne IR laser treatment on the changes of blood biochemical components in the rat liver damaged by the carbon tetrachloride (CCl₄). The twenty one Sprague-Dawley adult male rats weights (260±18.6 g) were designed to the three groups: one control group and two experimental groups, the experimental groups were divided into the CCl₄-treated groups and the laser therapy group (CCl₄+ Laser). The experimental groups were injected twice with CCl₄(1.0 ml/kg body weight) intraperitoneal for two days. Each group was sacrificed after two weeks irradiated with the lower power He-Ne IR laser for ten minutes per every day. The activity of alanine aminotransferase (ALT), lactic dehydrogenase (LDH), alkaline phosphatase (ALP) and the concentration of serum glucose treated with He-Ne IR laser groups was significantly decreased to the conrtol (treated with carbon CCl₄) group. The activity of aspartate aminotransferase (AST) was decreased in the laser group but not significantly, the concentration of the serum cholesterol in the laser group was significantly increased comparing with the control and case control groups. In conclusion, the effect of the lower power He-Ne IR laser treatment is believed to be a possible protective effects for CCl₄ induced acute hepatotoxicity in rats.

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일차 배양한 흰쥐의 간세포에서 사염화탄소로 인한 독성에 미치는 비테인의 효과 (Effects of Betaine on the $CCI_4$-Induced Toxicity in Primary Cultured Rat Hepatocytes)

  • 김선여;김홍표;이미경;김승희;문애리;한형미;허훈;김영중
    • 약학회지
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    • 제37권5호
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    • pp.499-503
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    • 1993
  • Betaine, a major component of Lycii Fructus, was evaluated for its anti-hepatotoxic activity on carbon tetrachloride-induced hepatotoxicity in primary cultured rat hepatocytes. Betaine was found to attenuate carbon tetrachloride-induced hepatotoxicity both morphologically and biochemically. Typical hepatocyte necrosis due to carbon tetrachloride seemed to be reduced by 50 to 500 $\mu{M}$ of betaine under microscopical observation. The value of glutamic pyruvic transaminase released from the hepatocytes into the medium significantly decreased as betaine concentration increased. Betaine also significantly elevated the reduced activities of some enzymes, cytochrome P-450, 7-ethoxycoumarin-0-deethylase and glutathione-S-transferase, involved in xenobiotic metabolism due to carbon tetrachloride-induced hepatotoxicity. These results demonstrate a possible hepato-protective role of betaine against fatty liver that could be easily induced by carbon tetrachloride.

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사염화탄소에 의하여 유발된 흰쥐의 간 독성에 미치는 비테인의 효과 (The Effect of Betaine on the $CCI_4$-Induced Hepatotoxicity in Rats)

  • 김선여;김홍표;이미경;변순정;김승희;문애리;한형미;허훈;김영중
    • 약학회지
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    • 제37권5호
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    • pp.538-543
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    • 1993
  • Effects of betaine, a major component of Lycii Fructus, on carbon tetrachloride intoxicated rats were evaluated. Histological studies showed that betaine had improved the typical necrosis around centrilobular area in liver tissue due to the carbon tetrachloride intoxication. Betaine, whether it was administrated simultaneously or prior to carbon tetrachloride, prevented or retarded the elevation of liver-weight/body-weight ratio due to the carbon tetrachloride intoxication. Betaine also significantly elevated the reduced activities of some enzymes, cytochrome P-450, 7-ethoxycoumarin-0-deethylase and glutathione-S-transferase, involved in xenobiotic metabolism due to carbon tetrachloride intoxication. These results demonstrate a possible hepato-protective role of betaine against fatty liver that could be easily induced by carbon tetrachloride in rat.

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