• Steel and Composite Structures
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• v.30 no.4
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• pp.383-392
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• 2019

Passive steel dampers have shown favorable performance in last earthquakes, numerical and experimental studies. Although steel dampers are more affordable than other types of damper, they are not economically justified for ordinary buildings. Therefore, in this paper, an innovative steel damper with shear yielding mechanism is introduced, which is easy to fabricate also can be easily replaced after sever earthquakes. The main goal of implementing such a mechanism is to control the possible damage in the damper and to ensure the elastic behavior of other structural components. The numerical results indicate an enhancement of the hysteretic behavior of the concentrically braced frames utilizing the proposed damper. The proposed damper change brittle behavior of brace due to buckling to ductile behavior due to shear yielding in proposed damper. The necessary relations for the design of this damper have been presented. In addition, a model has been presented to estimate load-displacement of the damper without needing to finite element modeling.

• Steel and Composite Structures
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• v.44 no.4
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• pp.569-586
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• 2022

This study introduces a novel friction damper as a component of a recentering frame connection, to solve the problem of structural repair costs, caused by stiffness deterioration and brittle fracture of the central brace frame (CBF). The proposed damper consists of shape memory alloy (SMA) bars with pretension applied to them to improve the stability. SMAs reduce the residual displacement by virtue of the properties of the materials themselves; in addition, a pretension can be applied to partially improve their energy dissipation capacity. The damper also consists of a friction device equipped with friction bolts for increased energy dissipation. Therefore, a study was conducted on the effects of the friction device as well as the pretension forces on the friction damper. For performance verification, 12 cases were studied and analyzed using ABAQUS program. In addition, the friction and pretension forces were used as variables in each case, and the results were compared. As a result, when the pretension and friction force are increased, the energy dissipation capacity gradually increases by up to about 94% and the recentering capacity decreases by up to about 55%. Therefore, it has been shown that SMA bars with adequate pretension in combination with bolts with adequate frictional force effectively reduce residual deformation and increase damper capacity. Thus, this study has successfully proposed a novel friction damper with excellent performance in terms of recentering and energy dissipation capacity.

• Nuclear Medicine and Molecular Imaging
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• v.41 no.1
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• pp.9-15
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• 2007

Purpose: Repetitive transcranial magnetic stimulation (rTMS) has recently been clinically applied in the treatment of drug resistant depressed patients. There are mixed findings about the efficacy of rTMS on depression. Furthermore, the influence of rTMS on the physiology of the brain is not clear. We prospectively evaluated changes of regional cerebral blood flow (rCBF) between pre- and post-rTMS treatment in patients with drug resistant depression. Materials and Methods: Twelve patients with drug-resistant depression (7 male, 5 female; age range: $19{\sim}52$ years; mean age: $29.3{\pm}9.3$ years) were given rTMS on right prefrontal lobe with low frequency (1 Hz) and on left prefrontal lobe with high frequency (20 Hz), with 20-minute-duration each day for 3 weeks. Tc-99m ECD brain perfusion SPECT was obtained before and after rTMS treatment. The changes of cerebral perfusion were analyzed using statistical parametric mapping (SPM; t=3.14, uncorrected p<0.01, voxel=100). Results: Following areas showed significant increase in rCBF after 3 weeks rTMS treatment: the cingulate gyrus, fusiform gyrus of right temporal lobe, precuneus, and left lateral globus pallidus. Significant decrement was noted in: the precental and middle frontal gyrus of right frontal lobe, and fusiform gyrus of left occipital lobe. Conclusion: Low-frequency rTMS on the right prefrontal cortex and high-frequency rTMS on the left prefrontal cortex for 3 weeks as an add-on regimen have increased and decreased rCBF in the specific brain regions in drug-resistant depressed patients. Further analyses correlating clinical characteristics and treatment paradigm with functional imaging data may be helpful in clarifying the pathophysiology of drug-resistant depressed patients.

• The Journal of the Acoustical Society of Korea
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• v.39 no.3
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• pp.179-190
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• 2020

In this paper, we estimated the Direction of Arrival (DOA) using Conventional BeamForming (CBF), adaptive beamforming and compressive beamforming. Minimum Variance Distortionless Response (MVDR) and Multiple Signal Classification (MUSIC) are used as the adaptive beamforming, and grid-free compressive sensing is applied for the compressive sensing beamforming. Theoretical background and limitations of each technique are introduced, and the performance of each technique is compared through simulation and real experiments. The real experiments are conducted in the presence of reflected signal, transmitting a sound using two speakers and receiving acoustic data through a linear array consisting of eight microphones. Simulation and experimental results show that the adaptive beamforming and the grid-free compressive beamforming have a higher resolution than conventional beamforming when there are uncorrelated signals. On the other hand, the performance of the adaptive beamforming is degraded by the reflected signals whereas the grid-free compressive beamforming still improves the conventional beamforming resolution regardless of reflected signal presence.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.6
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• pp.276-286
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• 2013

SVD-based deconvolution algorithm has been known as the most effective technique for CT perfusion image analysis. In this algorithm, in order to reduce noise effects, SVD coefficients smaller than a certain threshold are removed. As the truncation threshold, either a fixed value or a variable threshold yielding a predetermined OI (oscillation index) is frequently employed. Each of these two thresholding methods has an advantage to the other either in accuracy or efficiency. In this paper, we propose a Monte Carlo simulation method to evaluate the accuracy of the two methods. An extension of the proposed method is presented as well to measure the effects of image smoothing on the accuracy of the thresholding methods. In this paper, after the simulation method is described, experimental results are presented using both simulated data and real CT images.

• Magazine of the Korea Concrete Institute
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• v.6 no.1
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• pp.142-151
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• 1994

The purpose of this study is to investigate anti analyze the effect of iength of steel fiber and concrete admixt.ure such as iilica fume and fly ash on the workability arid engineering properties cbf steel fiber reinforced concxte (SFRC). As the results the follows art: found. First, it is poss ible to make steel fiber reinforced concrete having the consistency of IOcm slump and 28 days compressive strength of $600{\;}kgf/\textrm{m}^2$ by adopting low water binder ratios arid using :uperplasticizer. Second, the conipresslve and tensile strength of SWKC containing silica fume and fly ash is lower than those of plain concrete in the age after 28 days, but higher in the age after 28 days. Finally, tensde strength of SFHC is higher than that of plain concrete, and so adding the steel fibers in concrete increases the toughness.

• Journal of Nutrition and Health
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• v.36 no.8
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• pp.841-850
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• 2003

Soy-based formula has been used for centuries in Korea. Soybeans contain phytochemicals with a biochemically active component, isoflavone. Isoflavone is a kind of phytoestrogens, structurally and functionally similar to estrogen. This study was conducted to investigate the effects of soy-based infant formula on growth, development, and isoflavone concentration in the plasma and urine. Thirty-nine healthy infants who were delivered at K university medical center were recruited. Experimental groups were the breast milk group (n = 15, BM) who were fed breast milk, soy-based formula group (n = 10, SBF) who were fed soy-based infant formula, and the casein-based formula group (n = 14, CBF) who were fed casein-based infant formula for 4 months. HPLC analysis was used to measure the concentration of isoflavones. The measurements of infant weight, length, head circumference and chest circumference were all in the normal growth range and were similar among the experimental groups. No significant differences were found in the scores of total mean of infant development test (Development Quotient, DQ) among the experimental groups. The isoflavone content of soy-based formula was significantly higher than. that of breast milk and casein-based formula. Plasma concentration of daidzein and genistein in the infants fed soy-based formula (daidzein : 264.1 ng/ml, genistein : 392.1 ng/ml) was significantly higher (p<.0001) than that in infants fed breast milk (daidzein : 3.4 ng/ml, genistein : 3.8 ng/ml) and casein-based formula (daidzein: 8.1 ng/ml, genistein: 9.3 ng/ml). Also, urinary daidzein and genistein concentrations in infants fed soy-based formula (daidzein: 19.82 $\mu$g/ml, genistein : 17.89 $\mu$g/ml) were significantly higher (p<.001) than those in infants fed breast milk (daidzein: 0.28 $\mu$g/ml, genistein : 0.22 $\mu$g/ml) and casein-based formula (daidzein : 0.45 $\mu$g/ml, genistein : 0.33 $\mu$g/ml).

• Journal of Korean Society of Steel Construction
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• v.15 no.4 s.65
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• pp.379-388
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• 2003

The response of single story buildings and other case studies were investigated to observe trends and develop a better understanding of the impact of some design parameters on the seismic response of Concentrically Braced Frames (CBF). While many parameters are known to influence the behavior of braced frames, the focus of this study was mostly on quantifying energy dissipation in compression and its effectiveness on seismic performance. Based on dynamic analyses of single story braced frame and case studies, a bracing member designed with bigger R and larger KL/r was found to result in lower normalized cumulative energy ratio in both cases.

• International Journal of Oral Biology
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• v.37 no.2
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• pp.57-62
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• 2012

The nasal cavity encounters various irritants during inhalation such as dust and pathogens. To detect and remove these irritants, it has been postulated that the nasal mucosa epithelium has a specialized sensing system. The oral cavity, on the other hand, is known to have bitter taste receptors (T2Rs) that can detect harmful substances to prevent ingestion. Recently, solitary chemosensory cells expressing T2R subtypes have been found in the respiratory epithelium of rodents. In addition, T2Rs have been identified in the human airway epithelia. However, it is not clear which T2Rs are expressed in the human nasal mucosa epithelium and whether they mediate the removal of foreign materials through increased cilia movement. In our current study, we show that human T2R receptors indeed function also in the nasal mucosa epithelium. Our RT-PCR data indicate that the T2R subtypes (T2R3, T2R4, T2R5, T2R10, T2R13, T2R14, T2R39, T2R43, T2R44, T2R 45, T2R46, T2R47, T2R48, T2R49, and T2R50) are expressed in human nasal mucosa. Furthermore, we have found that T2R receptor activators such as bitter chemicals augments the ciliary beating frequency. Our results thus demonstrate that T2Rs are likely to function in the cleanup of inhaled dust and pathogens by increasing ciliary movement. This would suggest that T2Rs are feasible molecular targets for the development of novel treatment strategies for nasal infection and inflammation.

• Korean Journal of Oriental Medicine
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• v.12 no.2 s.17
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• pp.15-30
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• 2006

Background The Saam's Acupuncture Method is one of the most widely adopted techniques used by clinicians and educational institutions in Korea today. It is originated in the 17th century from a Buddhist monk known as 'Saam'. The reports on the bibliography. biological responses and therapeutic effects of Saam's Acupuncture method were done but trends on the Saam's Acupuncture method were insufficient. Objectives This study aims to review the bibliography, biological responses and therapeutic effects of Saam's Acupuncture. In the process, this review will grasp trends in this field of studies and will direct further researches into the right direction. Method We searched and investigated th journals supplied by Korean Oriental Medical Society and Je-Han Oriental Medical Academy homepage etc. with the key world 'Saam(사암), jung-geuk(정격), seung-gyuk(승격), han-geuk(한격), yul-geuk(열격)'. Fifty journals were chosen for the review. Result 1. The proportion of basic researches was 10%. The biological responses of Saam's Acupuncture method reveal on blood pressure, regional cerebral blood flow (rCBF). 2. The proportion of literature researches was 48%. The application of Saam's Acupuncture method was many. 3. The proportion of case reports was 26%. Saam's Acupuncture method is applied in the various disease. 4. The proportion of clinical studies was 16%. Clinical studies were increased after the year 2000. Conclusions To elevated quality of studies, we need well-designed experimental methods, efficient secure of experimental groups, appropriate statistical verification, accumulations of knowledges about data research.