• 제목/요약/키워드: CB-1A

검색결과 412건 처리시간 0.026초

뇌졸중환자(腦卒中患者)에 있어서 치료경과(治療經過)에 따른 뇌혈류(腦血流) 변화(變化) - Brain SPECT 결과(結果)를 중심(中心)으로 - (The change of CBF(cerebral blood flow) of CVA patients by oriental medical treatment - Focused on Brain SPECT results -)

  • 강화정;홍석;김종석;송호천;범희승;전상윤
    • 대한한방내과학회지
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    • 제21권1호
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    • pp.39-45
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    • 2000
  • Object : SPECT which can visualize the distribution of CBF was operated to find the basic evidence by objective and scientific inspection on the fact that how the oriental medical treatment for stroke patients can effect CBF. Method : This study made 18 cases an object of research. These patients came to the Dongshin Univ. Oriental Medical Hospical within 5 days from the first attack, were diagnosed as stroke from Brain CT and MAl and were in the hospital for over 4 weeks at least. They were taken acupunture treatment, negative technique and herbal medication. And this study operated SPECT at the instance of admission and at the 4th week after admission 2 times and compared the change of CBF. Results : I operated SPECT on 18 CVA patients and got a result on the change of blood supplies in brain as follows; In the 2nd SPECT compared with 1st, out of the 1st and 2nd SPECT, there are 10 cases(55.6%) of increase and 8 cases (44.4%) of decrease. According to L/Cb11 evauation standard, the 1 st and the 2nd changes of blood supplies in SPECT shows decrese from $0.830{\pm}0.071$ to $0.801{\pm}0.067$. On the other hand, according to L/C standard shows a minute increase from $0.894{\pm}0.079$ to $0.895{\pm}0.091$. But there is nothing meaningful. I treated patients' group with risk factors and the other patients' group without risk factors and observed the changes of blood supplies respectively. And therefore Patients' group without risk factors shows an meaningful increase of blood supplies from $0.835{\pm}0.076$ to $0.796{\pm}0.069$ L/Cbll and also an increase from $0.921{\pm}0.029$ to $0.939{\pm}0.029$ by L/C. But this result by L/C is not significant. Conclusion : As mentioned above, I treated CVA patients through oriental medical therapies using SPECT and researched the changes of blood supplies in their brains. But I could' t get any meaningful result. However, I think only after solving some problems in this treatment and quantifing the changes of blood supplies, this results can be the standard of scientific examination about oriental medical treatments.

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Effects of Dietary Fat Types on Growth Performance, Pork Quality, and Gene Expression in Growing-finishing Pigs

  • Park, J.C.;Kim, S.C.;Lee, S.D.;Jang, H.C.;Kim, N.K.;Lee, S.H.;Jung, H.J.;Kim, I.C.;Seong, H.H.;Choi, Bong-Hwan
    • Asian-Australasian Journal of Animal Sciences
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    • 제25권12호
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    • pp.1759-1767
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    • 2012
  • This study was performed to determine the effects of dietary fat sources, i.e., beef tallow, soybean oil, olive oil and coconut oil (each 3% in feed), on the growth performance, meat quality and gene expression in growing-finishing pigs. A total of 72 crossbred pigs (Landrace${\times}$Large White${\times}$Duroc) were used at $71{\pm}1$ kg body weight (about 130 d of age) in 24 pens ($320{\times}150$ cm) in a confined pig house (three pigs per pen) with six replicate pens per treatment. The growing diet was given for periods of $14{\pm}3$ d and the finishing diet was given for periods of $28{\pm}3$ d. The fat type had no significant effect either on growth performance or on chemical composition or on meat quality in growing-finishing pigs. Dietary fat type affected fatty acid composition, with higher levels of unsaturated fatty acids (UFAs) and monounsaturated fatty acids (MUFAs) in the olive oil group. Microarray analysis in the Longissimus dorsi identified 6 genes, related to insulin signaling pathway, that were differentially expressed among the different feed groups. Real time-PCR was conducted on the six genes in the longissimus dorsi muscle (LM). In particular, the genes encoding the protein kinase, cAMP-dependent, regulatory, type II, alpha (PRKAR2A) and the catalytic subunit of protein phosphatase 1, beta isoform (PPP1CB) showed the highest expression level in the olive oil group (respectively, p<0.05, p<0.001). The results of this study indicate that the type of dietary fat affects fatty acid composition and insulin signaling-related gene expression in the LM of pigs.

염료감응형 광전기화학 물분해 전지용 Tri-branched tri-anchoring organic dye 개발 (Tri-branched tri-anchoring organic dye for Visible light-responsive dye-sensitized photoelectrochemical water-splitting cells)

  • 박정현;김재홍;안광순
    • 한국신재생에너지학회:학술대회논문집
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    • 한국신재생에너지학회 2010년도 춘계학술대회 초록집
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    • pp.87-87
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    • 2010
  • Photoelectrochemical (PEC) systems are promising methods of producing H2 gas using solar energy in an aqueous solution. The photoelectrochemical properties of numerous metal oxides have been studied. Among them, the PEC systems based on TiO2 have been extensively studied. However, the drawback of a PEC system with TiO2 is that only ultraviolet (UV) light can be absorbed because of its large band gap (3.2 - 3.4 eV). Two approaches have been introduced in order to use PEC cells in the visible light region. The first method includes doping impurities, such as nitrogen, into TiO2, and this technique has been extensively studied in an attempt to narrow the band gap. In comparison, research on the second method, which includes visible light water splitting in molecular photosystems, has been slow. Mallouk et al. recently developed electrochemical water-splitting cells using the Ru(II) complex as the visible light photosensitizer. the dye-sensitized PEC cell consisted of a dye-sensitized TiO2 layer, a Pt counter electrode, and an aqueous solution between them. Under a visible light (< 3 eV) illumination, only the dye molecule absorbed the light and became excited because TiO2 had the wide band gap. The light absorption of the dye was followed by the transfer of an electron from the excited state (S*) of the dye to the conduction band (CB) of TiO2 and its subsequent transfer to the transparent conducting oxide (TCO). The electrons moved through the wire to the Pt, where the water reduction (or H2 evolution) occurred. The oxidized dye molecules caused the water oxidation because their HOMO level was below the H2O/O2 level. Organic dyes have been developed as metal-free alternatives to the Ru(II) complexes because of their tunable optical and electronic properties and low-cost manufacturing. Recently, organic dye molecules containing multi-branched, multi-anchoring groups have received a great deal of interest. In this work, tri-branched tri-anchoring organic dyes (Dye 2) were designed and applied to visible light water-splitting cells based on dye-sensitized TiO2 electrodes. Dye 2 had a molecular structure containing one donor (D) and three acceptor (A) groups, and each ended with an anchoring functionality. In comparison, mono-anchoring dyes (Dye 1) were also synthesized. The PEC response of the Dye 2-sensitized TiO2 film was much better than the Dye 1-sensitized or unsensitized TiO2 films.

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Estimation of Rumen Microbial Protein Supply Using Urinary Purine Derivatives Excretion in Crossbred Calves Fed at Different Levels of Feed Intake

  • Singh, M.;Sharma, K.;Dutta, N.;Singh, P.;Verma, A.K.;Mehra, U.R.
    • Asian-Australasian Journal of Animal Sciences
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    • 제20권10호
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    • pp.1567-1574
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    • 2007
  • A study was carried out to study the response of total purine derivatives (PD) excretion in urine to determine microbial N (MN) supply at four fixed levels of feed intake (namely 95, 80, 60 and 40% of voluntary intake). The crossbred (CB) calves were allocated according to a $4{\times}4$ Latin Square Design and fed wheat straw and concentrate (1:1). The rate of PD excretion (mmol/d) as a linear function of feed intake was 15.85/kg DMI and 20.12/kg DOMI. Based on the endogenous and PD excretion rates obtained in this study, a relationship between daily urinary PD excretion (Y, mmol) and daily microbial protein supply (X, mmol) was developed for crossbred calves as Y = 0.83X+0.296 kg $W^{0.75}$. The derived microbial N values using this equation differed (p<0.001) among the 4 groups and was the highest in L-95 followed by L-80, L-60 and L-40. The relationship between urinary nitrogen loss (Y, g/d) and DOMI (X, kg/d) was established as: Y = 6.038X+21.753 ($r^2$ = 0.663, p<0.01). When urinary excretion of PD (Y, mmol/d) was plotted against intake of DM and DOM (X, kg/d), the equations obtained were: Y = 7.1711X+8.674 ($r^2$ = 0.889, p<0.01) and Y = 12.434X+7.683 ($r^2$ = 0.896, p<0.01), respectively. The proportional contribution of allantoin and uric acid to total PD remained stable irrespective of level of feed intake. Similarly, urinary excretion of creatinine did not differ (p>0.05) between animals fed at different levels. The MN supply was the highest to animals at intake levels L-95, and decreased linearly with corresponding decrease in feed intake. However, the MN supply when expressed per kg DOMI remained statistically (p>0.05) similar irrespective of level of intake. The results revealed that the excretion of urinary purine derivatives were positively correlated with the level of feed intake as well as rumen microbial supply and thus it could be a good indicator for measuring the microbial protein supply and nutritional status of animals.

Beacon 위치측위 기술과 행정주소를 연계한 재난재해 상황 전파 연구 (A Study on the Diffusion of Emergency Situation Information in Association with Beacon Positioning Technology and Administrative Address)

  • 모은수;이재광
    • 정보처리학회논문지:컴퓨터 및 통신 시스템
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    • 제5권9호
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    • pp.211-216
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    • 2016
  • 최근 전세계적으로 지진, 홍수, 화재 등 재난재해로 인한 인명피해가 늘어나면서 골든타임을 확보하기 위한 기술연구가 활발히 이루어지고 있다. 본 논문에서는 골든타임 확보를 위해 IoT 기술들을 사용해 재난 재해 발생 시 실제 발생원의 사용자를 최우선으로 찾아 전파하며, 주변지역 사용자로 차츰 범위를 확산시켜 전파하는 모델을 연구하였다. 국가 재난 재해 정보는 기상청 OPEN API를 사용하였으며, 해당지역의 세밀한 정보획득을 실시간 수집하기 위해 Crowd Sensing 기술과 BLE (Bluetooth Low Energy) Beacon 기술을 통합 연계한 시스템을 구축하였다. 특히 기존까지 기지국 기반 CBS를 사용하였다면 본 논문에서는 Beacon을 이용한 사용자 위치와 국가행정주소체계 네가지를 통합한 DB를 설계하여 맵핑함으로써 지역 사용자를 추정할 수 있게 되었다. 실험은 사용자의 수를 1천명씩 증가하는 방식을 통해 정보 확산 알고리즘의 정확도와 속도를 측정하였으며, 최종 2만명의 인원까지 1초 이내 연산하여 위험 전파 알림이 가능함을 확인하였다.

구강점막 상피세포에 대한 치과 주조용 비귀금속 합금의 세포독성 (CYTOTOXICITY OF DENIAL CAST BASE METAL ALLOYS ON HUMAN ORAL KERATINOCYTES)

  • 최영진;육종인;정문규
    • 대한치과보철학회지
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    • 제37권6호
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    • pp.717-729
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    • 1999
  • Although many studies on the cytotoxicity of the dental cast base metal alloys and their components have been carried out, the results are rather conflicting because of the different type of cells used and the various experimental procedures taken. Recently a number of scientists have claimed that it would be preferable to focus on the use of cells from relevant specific location of the human bodies. Consequently, the primary cultured oral keratinocyte derived from oral mucous along with nickel chloride and several of widely used dental cast base metal alloys(two Ni-Cr alloys and one Co-Cr alloy)in domestic were selected for this study, from which 1) The amounts of released metal ions were determined using atomic absorption spectrometry, 2) The cytotoxicity of nickel chloride and dental cast base metal alloys was evaluated via MTT assay, and finally, 3) The amounts of released metal ions and the cytotoxicity of nickel chloride were correlated with the cytotoxicity of dental cast base metal alloys And, the results were summarized as follows; 1. Nickel ion from Ni-Cr alloys and Cobalt ion from Co-Cr alloys resulted in maximum releasing rate during first 2h hours, followed by a decrease in releasing rate with time. Chromium ion were found to be minimal in all alloys. 2. In cytotoxic test. with $40{\mu}M,\;80{\mu}M$ of nickel chloride, there were observed an increase in the relative cell number compared to control samples after 24 hours. With $160{\mu}M$, there was found to be no difference in the relative cell number with control, except that 48 hour showed a increase in relative cell number. With $320{\mu}M$, the relative cell number remained constant and decreased after 48 hours, and with $640{\mu}M$, a continuing decrease in relative cell number was observed throughout test period. 3 The sensitivity of primary cultured oral epithelium to nickel was lower compared to the cells used in other studies. 4. CB-80 Soft and Regalloy showed no cytotoxicity to primary cultured oral epithelium and New crown resulted in a slight cytotoxicity. In conclusion, it was shown that the primary cultured oral keratinocytes could be applied successfully as testing cells in cytotoxicity test. Futhermore, the dental cast base metal alloys used in this study were found to be biocompatible.

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치과용 cone beam CT를 이용한 한국인 소아 및 청소년의 매복 정중과잉치에 대한 3차원적 분석 (Three-Dimensional Evaluation of Impacted Mesiodens Using Dental Cone-Beam Computed Tomography in Korean Children and Adolescents)

  • 김상덕;이상호;이난영;전상윤
    • 대한소아치과학회지
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    • 제40권3호
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    • pp.149-158
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    • 2013
  • 이 연구의 목적은 치과용 3차원 Come-beam CT 영상을 이용하여 정중과잉치의 형태와 매복 양상 및 연관된 합병증에 대해 평가하는 것이다. 2007년부터 2012년까지 정중과잉치를 주소로 조선대학교 치과병원 소아치과에 내원한 280명의 환아의 cone-beam CT 영상을 평가하였다. 매복된 정중과잉치는 여아보다 남아에서 더 빈번했고, 약 3.3 : 1의 비율을 보였으며 6~8세에서 가장 많이 관찰되었다. 환자당 정중과잉치의 개수는 1.38개였다. 대부분의 정중과잉치는 원추형(79.5%)이었으며, 역위방향(48.6%)으로 위치하고 있었다. 근원심적 위치로는 정중부(81.8%)가 가장 흔했고, 수직적으로는 치경부 근처(60.3%)에 가장 많이 분포하였으며, 순구개측 위치로는 구개측(73.8%)에 가장 많이 위치였다. 정중과잉치의 47.5%에서 합병증이 관찰되었고 인접치 변위와 맹출 지연이 가장 흔했다. 과잉치의 형태와 수직적 위치, 그리고 순구개측 위치가 합병증과 상관관계를 보였다. Cone-beam CT는 매복된 정중과잉치에 대한 3차원적 위치 정보와 정확한 영상을 제공하였다.

A Study of Segmental and Syllabic Intervals of Canonical Babbling and Early Speech

  • Chen, Xiaoxiang;Xiao, Yunnan
    • 비교문화연구
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    • 제28권
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    • pp.115-139
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    • 2012
  • Interval or duration of segments, syllables, words and phrases is an important acoustic feature which influences the naturalness of speech. A number of cross-sectional studies regarding acoustic characteristics of children's speech development found that intervals of segments, syllables, words and phrases tend to change with the growing age. One hypothesis assumed that decreases in intervals would be greater when children were younger and smaller decreases in intervals when older (Thelen,1991), it has been supported by quite a number of researches on the basis of cross-sectional studies (Tingley & Allen,1975; Kent & Forner,1980; Chermak & Schneiderman, 1986), but the other hypothesis predicted that decreases in intervals would be smaller when children were younger and greater decreases in intervals when older (Smith, Kenney & Hussain, 1996). Researchers seem to come up with conflicting postulations and inconsistent results about the change trends concerning intervals of segments, syllables, words and phrases, leaving it as an issue unresolved. Most acoustic investigations of children's speech production have been conducted via cross-sectional designs, which involves studying several groups of children. So far, there are only a few longitudinal studies. This issue needs more longitudinal investigations; moreover, the acoustic measures of the intervals of child speech are hardly available. All former studies focus on word stages excluding the babbling stages especially the canonical babbling stage, but we need to find out when concrete changes of intervals begin to occur and what causes the changes. Therefore, we conducted an acoustic study of interval characteristics of segments and words concerning Canonical Babble ( CB) and early speech in an infant aged from 0;9 to 2;4 acquiring Mandarin Chinese. The current research addresses the following two questions: 1. Whether decreases in interval would be greater when children were younger and smaller when they were older or vice versa? 2. Whether the child speech concerning the acoustic features of interval drifts in the direction of the language they are exposed to? The female infant whose L1 was Southern Mandarin living in Changsha was audio- and video-taped at her home for about one hour almost on a weekly basis during her age range from 0;9 to 2;4 under natural observation by us investigators. The recordings were digitized. Parts of the digitized material were labeled. All the repetitions were excluded. The utterances were extracted from 44 sessions ranging from 30 minutes to one hour. The utterances were divided into segments as well as syllable-sized units. Age stages are 0;9-1;0,1;1-1;5, 1;6-2;0, 2;1-2;4. The subject was a monolingual normal child from parents with a good education. The infant was audio-and video-taped in her home almost every week. The data were digitized, segments and syllables from 44 sessions spanning the transition from babble to speech were transcribed in narrow IPA and coded for analysis. Babble was coded from age 0;9-1;0, and words were coded from 1;0 to 2;4, the data has been checked by two professionally trained persons who majored in phonetics. The present investigation is a longitudinal analysis of some temporal characteristics of the child speech during the age periods of 0;9-1;0, 1;1-1;5, 1;6-2;0, 2;1-2;4. The answer to Research Question 1 is that our results are in agreement with neither of the hypotheses. One hypothesis assumed that decreases in intervals would be greater when children were younger and smaller decreases in intervals when older (Thelen,1991); but the other hypothesis predicted that decreases in intervals would be smaller when children were younger and greater decreases in intervals when older (Smith, Kenney & Hussain, 1996). On the whole, there is a tendency of decrease in segmental and syllabic duration with the growing age, but the changes are not drastic and abrupt. For example, /a/ after /k/ in Table 1 has greater decrease during 1;1-1;5, while /a/ after /p/, /t/ and /w/ has greater decrease during 2;1-2;4. /ka/ has greater decrease during 1;1-1;5, while /ta/ and /na/ has greater decrease during 2;1-2;4.Across the age periods, interval change experiences lots of fluctuation all the time. The answer to Research Question 2 is yes. Babbling stage is a period in which the children's acoustic features of intervals of segments, syllables, words and phrases is shifted in the direction of the language to be learned, babbling and children's speech emergence is greatly influenced by ambient language. The phonetic changes in terms of duration would go on until as late as 10-12 years of age before reaching adult-like levels. Definitely, with the increase of exposure to ambient language, the variation would be less and less until they attain the adult-like competence. Via the analysis of the SPSS 15.0, the decrease of segmental and syllabic intervals across the four age periods proves to be of no significant difference (p>0.05). It means that the change of segmental and syllabic intervals is continuous. It reveals that the process of child speech development is gradual and cumulative.

Quantified Analyses of Musk Deer Farming in China: A Tool for Sustainable Musk Production and Ex situ Conservation

  • Meng, Xiuxiang;Gong, Baocao;Ma, Guang;Xiang, Leilei
    • Asian-Australasian Journal of Animal Sciences
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    • 제24권10호
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    • pp.1473-1482
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    • 2011
  • Adult male musk deer (Moschus spp.) secrete musk, a widely used ingredient in traditional Asian medicine and the international perfume industry. Musk deer are endangered due to historic over-utilization of musk and habitat loss. Musk deer farming, provides an important way of conserving musk deer and ensuring a sustainable musk supply. For over 50 years musk deer farming has been conducted in China with the endangered Alpine musk deer (Moschus sifanicus) the predominant farmed musk deer species. To date, few studies have examined the musk production of captive musk deer. This study analyzed musk-extraction data collected from 1997 to 2009 at Xinglongshan Musk Deer Farm, Gansu, China. The musk-extraction ratio (MER) of captive male musk deer was 90.30% (n = 732), while the annual average musk extraction (AME) per animal was $7.90{\pm}0.17\;g$ with the range from 0.00 g to 34.20 g (n = 732). The origin of the deer had an influence on AME and MER production, with male wild-captured (WC) individuals recording higher values (AME, $8.76{\pm}0.27\;g$, n = 272; MER, 93.75%, n = 272) than those of captive breeding (CB) males (AME: $7.39{\pm}0.22\;g$, n = 460; MER: 88.26%, n = 460). The origin of an individual's parents, however, did not influence AME and MER. Age also influenced musk production with the MER of 1.5-year-old males being 87.5% with an average musk production of $8.27{\pm}0.47\;g$ (n = 96). The peak period for musk production was from 1.5 to 8.5 years of age. The results of our study demonstrate musk deer farming could work as an effective measure to protect musk deer and provide sustainable musk resources, however, the musk production including MER and AME could be improved through optimizing the managing and breeding system in endangered musk deer farming.

잠양자음약물(潛陽滋陰藥物)이 뇌출혈(腦出血) 환자(患者)의 고혈압(高血壓)에 미치는 영향(影響)에 대한 임상적(臨床的) 고찰(考察) (The clinical study of the effect of Jamyang.Jaum prescriptions on the hypertension evolution in cerebral hemorrhage patients)

  • 최철원;김동웅;신선호;전희준;황보연;정대영
    • 대한한의학회지
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    • 제18권1호
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    • pp.72-81
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    • 1997
  • The causes of stroke are presumed hypertension, atherosclerosis,. cardiac disease, diabetes mellitus and old age and risk factors of stroke are suggested hypertension, hyperlipidemia. obesity, smoking and drinking etc. Especilly, hypertension is one of the most important cause and risk factor of stroke, therfore without therapy hypertension leads to stroke. The frequence of hypertension is significantly higher in hemorrhage patients of intracranial hemorrhage and subarachnoid hemorrhage. Antihypertensive therapy has an impact not only on the primary prevention of stroke but also on stroke recurrence and the declining of stroke motality has been attributed to the widespread availability and use of antihypertensive therapy. The goals of antihypertensive therapy decrease the complications and motalitv of cardiovascular system and prevent the promoting arteriosclerosis. In this study, we observed the blood pressure change of cb-hemorrhagic patients with hypertension who were hospitalized from 1996. 3. 1 to 1997. 2 .26 in Wonkwang Oriental Hospital. These patients had no antihypertensive therapy and were supplied herb med(Jaum sikpoongtang, Chungrijagamtang, Gojinumja) in medication. Our results suggested as follows. 1. Systolic and diastolic average BP at admission is $150.71{\pm}15.61mmHg$ and $95.00{\pm}8.8mmHg$ and this is hypertension state defining WHO 2. During one week in admission, the blood pressure demostrated a marked declination by SBP 8.97mmHg and DBP 6.22mmHg. 3. During two week in admission, the declination of SBP was significant in paired t-test(p<0.05) but, the declination of DBP was non-significant in paired t-test. 4. The blood pressure during third and fourth weeks gradually declined but, non-significant in test. According to the above results, we suggested that the BP declination Was affected by $Jamyang{\cdot}Jaum$ prescriptions in acute stage of cerebral hemorrhage.

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