• Journal of Pharmacopuncture
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• v.18 no.1
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• pp.56-62
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• 2015

Objectives: The purpose of the study is to assess both the approximate lethal dose and the single dose intramuscular injection toxicity of Danggui (Angelica gigantis radix) pharmacopuncture (DGP) in Sprague-Dawley (SD) rats. Methods: The experiments were conducted at the good laboratory practice (GLP) laboratory, Biotoxtech Co., which is a laboratory approved by the ministry of food and drug safety (MFDS). The study was performed according to the GLP regulation and the toxicity test guidelines of the MFDS (2009) after approval of the institutional animal care and use committee of Biotoxtech. Single doses of DGP were injected intramuscularly into the rats in three test groups of 6 week old SD rats (5 male and 5 female rats per groups) in the amounts of 0.1, 0.5, and 1.0 mL/animal for groups 2, 3, and 4, respectively, and normal saline solution in the amount of 1.0 mL/animal was injected intramuscularly into the rats (5 male and 5 female rats) in the control group. Observations of the general symptoms and weight measurements were performed during the 14 day observation period after the injection. Hematologic and serum biochemical examination, necropsy, and a local tolerance test at the injection site were done after the observation period. Results: No death was observed in three test groups (0.1, 0.5 and 1.0 mL/animal group). In addition, the injection of DGP had no effect on general symptoms, weights, hematologic and serum biochemical examination, and necropsy. The results from the local tolerance tests at injection site showed no treatment related effects in the SD rats. Conclusion: The results of single dose intramuscular injection of DGP suggest that the approximate lethal dose is above 1.0 mL/animal for both male and female SD rats and that intramuscular injection of DGP may be safe.

• Journal of the Korean Institute of Landscape Architecture
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• v.44 no.4
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• pp.75-85
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• 2016

In recent years, natural healing space studies have been done in health care and forestry. However, previous studies have focused on healing effects of natural elements in interior space or natural landscape view. And there is a limit to using the evidence for healing space design. The aim of this study is to discover the relationship between types and effects of healing space for evidence-based design. This study compares and analyzes the mayor images, psychological restorativeness, and satisfaction to identify the effects and differences of natural trail, designed trail, natural shelter, and designed shelter by types of forest space. Collected data is analyzed with a factorial analysis, valiance analysis and multiple regression analysis in SPSS 18.0. The results of this study are as follows: 1) Among five factors consisting psychological restorativeness, natural trail can be achieved with 'being away' and 'compatibility' and designed shelter can be achieved with 'fascination' and 'coherence'., 2) Psychological restorativeness values higher in images with higher excitement, brightness, vitality, and beautifulness as well as in images with lower level of disorder., 3) Among five factors consisting psychological restorativeness, higher forest satisfaction can be achieved with a higher level of 'being away' and 'coherence'. In conclusion, this study contributes to providing fundamental information for design guidelines of healing spaces through identifying the characteristics of healing environment by types of forest space.

• Annals of Geriatric Medicine and Research
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• v.22 no.4
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• pp.167-175
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• 2018

Sarcopenia, a common clinical syndrome in older adults, is defined as decreased muscle mass, strength, and physical performance. Since sarcopenia is associated with the incidence of functional decline, falls, and even mortality in older adults, researchers and health care providers have been keen to accumulate clinical evidence to advocate the screening and prevention of sarcopenia progression in older adults. The factors that may accelerate the loss of muscle mass and function include chronic diseases, inactivity, and deficiency in appropriate nutritional support. Among these, nutritional support is considered an initial step to delay the progression of muscle wasting and improve physical performance in community-dwelling older adults. However, a nationwide study suggested that most Korean older adults do not consume sufficient dietary protein to maintain their muscle mass. Furthermore, considering age-associated anabolic resistance to dietary protein, higher protein intake should be emphasized in older adults than in younger people. To develop a dietary protein recommendation for older adults in Korea, we reviewed the relevant literature, including interventional studies from Korea. From these, we recommend that older adults consume at least 1.2 g of protein per kg of body weight per day (g/kg/day) to delay the progression of muscle wasting. The amount we recommend (1.2 g/kg/day) is 31.4% higher than the previously suggested recommended daily allowance (i.e., 0.91 g/kg/day) for the general population of Korea. Also, evidence to date suggests that the combination of exercise and nutritional support may enhance the beneficial effects of protein intake in older adults in Korea. We found that the current studies are insufficient to build population-based guidelines for older adults, and we call for further researches in Korea.

• 한국노년학
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• v.38 no.3
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• pp.501-519
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• 2018

The purpose of this study was to explore perception about shared decision making of family caregivers of patients with early dementia (PWED). This study was conducted with a sample of 12 family caregivers (mean age = $71.4{\pm}10.4$) of PWED from three dementia safety centers in Seoul. In-depth interviews were done for each participant about shared decision making and data were analyzed using qualitative content analysis. Six categories and 17 sub-categories identified for participants' perception about shared decision making: means to facilitate communication with patients with dementia, means to secure autonomy of patients, opportunity to facilitate treatment, cause of increasing family caregivers' burden, cause of worsening relationship with patients, and option for choices depending on priority change. The findings of this study can provide a knowledge basis for health care professionals and policy makers to understand how family caregivers of PWED think about shared decision making. It would be of great value to develop educational programs and practical guidelines about shared decision making for PWED and their family, which may contribute to respecting PWED's self-determination right as well as reducing burden of their family.

• The Journal of the Korea Contents Association
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• v.18 no.11
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• pp.462-474
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• 2018

The development of bio-sensing technology made it easy to collect various biometric information that was only available in large medical devices. The miniaturization of sensors makes it simple to carry out various health checkups that It did in person to the hospital by improving the portability of diagnostic devices. It is able to combine sensors into portable devices such as Smartphones, apply advanced Internet of Things (IOT) technology, and create new form factors for medical devices such as ultra-small modules that can be inserted or attached to their bodies. The results can be checked immediately through portable information devices such as smart phones. Although commercialization is still slow in Korea, new technologies are being applied in various ways in countries such as the United States that have granted remote medical services. Medical demand, supply and cost in South Korea are growing ahead of a super-aged society. Under these circumstances, attention is focusing on whether smart healthcare, a new concept, can complement the existing medical system. This study identifies the technology trends associated with smart health care and categorizes various healthcare products in the UX design aspects. In addition, the UX design approach and guidelines for applying smart healthcare technologies to the elderly, the intended users, are presented. This research will provide a reference to a new social issue, the UX-design approach to solving the problems of the aged society.

• Journal of Genetic Medicine
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• v.15 no.2
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• pp.72-78
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• 2018

Purpose: Physicians' attitudes may have a strong influence on women's decision regarding prenatal screening options. The aim of this study is to assess the physicians' attitudes toward prenatal screening for fetal aneuploidy including non-invasive prenatal testing (NIPT) in South Korea. Materials and Methods: Questionnaires were distributed and collected at several obstetrics-gynecological conferences and meetings. The questionnaire included 31 multiple choice and 5 fill-in-the-blank questions. Seven questions requested physicians' demographic information, 17 questions requested information about the NIPT with cell-free fetal DNA, and 12 questions requested information about general prenatal screening practices. Results: Of the 203 obstetricians that completed the survey. In contrast with professional guidelines recommending the universal offering of aneuploidy screening, only 53.7% answered that prenatal aneuploidy testing (screening and/or invasive diagnostic testing) should be offered to all pregnant women. Physicians tended to have positive attitudes toward the clinical application of NIPT as both primary and secondary screening methods for patients at high-risk for fetal trisomy. However, for patients at average-risk for fetal trisomy, physicians tended to have positive attitudes only as a secondary screening method. Physicians with more knowledge about NIPT were found to tend to inform their patients that the detection rate of NIPT is higher. Conclusion: This is the first study to investigate expert opinion on prenatal screening in South Korea. Education of physicians is essential to ensure responsible patient counseling, informed consent, and appropriate management after NIPT.

• The Journal of the Korea Contents Association
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• v.19 no.9
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• pp.271-279
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• 2019

The life expectancy of people has been steadily extended due to the improvement of living standards and the development of medical technology. Besides, the low birth rate and long life expectancy decrease the youth population while the elderly population is steadily increasing. Many elderly people have enough time and financial allowance, and the interest in health care is increased all over society. There are also increasing numbers of elderly people who exercise lightly in the playgrounds and parks such as running and walking. Outdoor fitness equipment that can be easily seen in neighbourhood parks, public spaces, etc. can be good health promotion tools that can be easily accessed in the daily life of the elderly. Outdoor fitness equipment Description Signs require a design that takes into account the declining vision of older users. Proper design is also important for the prevention of safety accidents in use. The purpose of this study is to find out the perception of the elderly about outdoor fitness exercise equipment sign system and to find the problem of recognition. To do this, we conduct user observation and interview surveys for the elderly. As a result, the emphasis of the caveat or problems with the size of the writing were pointed out, and it was necessary to explain the picture rather than the text. Also, there was a high demand for refraining from using foreign words, using universal words and including motor effects in signs. Based on the results of the user observation and interviews, we propose guidelines for the use of outdoor exercise equipment.

• Journal of the Korean Society of Radiology
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• v.79 no.5
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• pp.247-253
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• 2018

The purpose of this study was to summarize the results of a survey for physicians with specialties other than radiology about imaging studies of patients referred from other institutions. The survey was promoted through individual contacts or social network service and physicians who voluntarily responded to the survey were the subjects of the study. The questionnaire consisted of 11 questions about basic information and referrals about medical imaging. A total of 160 physicians from 30 specialties participated in the survey and 95.6% of the respondents worked in tertiary care center or general hospital. Patients were frequently referred with outside medical images. The most frequently referred imaging modalities were computed tomography and magnetic resonance imaging. However, radiological reports from outside institutions were rarely referred. Most physicians thought that reinterpretation for outside imaging is necessary to acquire a secondary opinion. In conclusion, considering that outside radiological reports are frequently missing and there are high demands on reinterpretation for outside imaging, guidelines for referral of radiological reports with medical imaging, basic elements of radiological reports, and reinterpretation need to be developed.

• Journal of Practical Engineering Education
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• v.13 no.2
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• pp.251-259
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• 2021

Due to the characteristic that early childhood education is a process of nurturing children's senses by a leader rather than the transfer of knowledge, even in the era of with Corona, early childhood distance education is not one-to-one non-face-to-face education, but rather through distributed materials such as early childhood education packages or media such as TV. Distance education was conducted in a self-care method. Through a review of prior research and intensive parent interviews, the researcher identified the requirements for distance education, such as the expansion and accessibility of educational contents, understanding of basic knowledge of early childhood distance education, and the need to increase children's social skills through real-time distance education. It was identified that the current distance education-related solutions are not suitable for early childhood education. Accordingly, the researcher presents the basic direction (VERI) of the early childhood distance education solution of diversity, ease, real-time communication, and integration, and provides a Web/App platform that allows children, parents, and teachers to share content and communicate in real time and in non-real time. The development of a solution was proposed. This distance education solution is expected to effectively support early childhood distance education in the era of With Corona as infants, parents, and teachers communicate and share the current situation, which is only presenting guidelines and materials.

• Journal of Dental Rehabilitation and Applied Science
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• v.37 no.2
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• pp.81-87
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• 2021

Purpose: To profile various clinical characteristics of sleep bruxism (SB) patients with idiopathic facial pain (IFP) in the orofacial region. Materials and Methods: We analyzed 28 SB patients among 210 patients with IFP complaints. The profiles were evaluated using patient charts including gender, age, pain duration, pain location, pain intensity and affected areas by pain. Results: SB with IFP occurred more often in females (85.7%) than males (14.3%). The mean age at presentation was 48.9 years. The most common IFP sites of SB patients were the right maxilla (28.6%) and the right mandible (25.0%). The pain complaints occurred mostly in 2 teeth or areas (50.0%), followed by 1 area (28.6%) and then in ≥ 3 teeth or areas (21.4%). The mean pain intensity was 5.9 on a visual analogue scale from 0 to 10. The pain was spontaneous in 20 patients (71.4%), and the mean pain duration was 24.4 months. Conclusion: Identification of clinical characteristics of SB patients with IFP could be useful in the diagnosis of various IFP patients and beneficial in decreasing unnecessary care to reduce IFP. Further studies with larger number of subjects and extended duration are required for more systemized diagnostic methods and development of future treatment guidelines.