• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2005.06a
• /
• pp.611-614
• /
• 2005

It is well known that tire tread pattern has much influence on the tire pattern noise. The paper describes the method of pattern noise reduction by using the pitch sequence, both on the smooth asphalt roads and on the trenched concrete roads. The noise of tire is classified as either airborne or structure borne noise. Pattern noise through the airborne is considered as a major noise source at high speeds. As block impacting and air pumping by tread patterns are major noise source, tire pattern noise can be greatly influenced by optimal pitch sequence. The goal of this paper is to provide tire engineers with pitch sequence to reduce pattern noise effectively.

• Bulletin of the Korean Chemical Society
• /
• v.27 no.8
• /
• pp.1194-1198
• /
• 2006

For the purpose of developing more effective chelating agents, we have synthesized a diethylene triamine pentaacetic acid(DTPA) analogue by using an amino acid. S-(N-Boc-aminophenyl)-Cys(t-Bu4-DTPA) methylester was prepared in 6 steps with total yield of 47.9%. For the sake of introducing a biomolecule to the DTPA derivative, a selective hydrolysis was performed with 3 M HCl/Ethylacetate = 1 : 3 ($25{^{\circ}C}$, 30 min, vigorous stirring). $^{166}Ho$-Cys-DTPA and $^{166}Ho$-Biotin-Cys-DTPA were prepared by mixing $^{166}Ho$ with DTPA derivatives at room temp in a HCl solution (pH = 5) and the radiochemical stabilities (> 99%) were maintained for over 6 hrs in vitro.

• East Asian mathematical journal
• /
• v.27 no.3
• /
• pp.261-271
• /
• 2011

In this paper, fuzzy ${\alpha}^*$-set, fuzzy C-set, fuzzy AB-set, fuzzy t-set, fuzzy B-set, etc., are introduced in the sense of Sostak [12] and Ramadan [9]. By using these sets, a decomposition of fuzzy continuity and complete fuzzy continuity are provided. Characterization of smooth fuzzy extremally disconnected spaces is also obtained in this connection.

• Animal Bioscience
• /
• v.35 no.3
• /
• pp.399-409
• /
• 2022

Objective: Follicle-stimulating hormone (FSH) is the central hormone involved in mammalian reproduction, maturation at puberty, and gamete production that mediates its function by control of follicle growth and function. The present study investigated the mutations involved in the regulation of FSH receptor (FSHR) activation. Methods: We analyzed seven naturally-occurring mutations that were previously reported in human FSHR (hFSHR), in the context of equine FSHR (eFSHR); these include one constitutively activation variant, one allelic variant, and five inactivating variants. These mutations were introduced into wild-type eFSHR (eFSHR-wt) sequence to generate mutants that were designated as eFSHR-D566G, -A306T, -A189V, -N191I, -R572C, -A574V, and -R633H. Mutants were transfected into PathHunter EA-parental CHO-K1 cells expressing β-arrestin. The biological function of mutants was analyzed by quantitating cAMP accumulation in cells incubated with increasing concentrations of FSH. Results: Cells expressing eFSHR-D566G exhibited an 8.6-fold increase in basal cAMP response, as compared to that in eFSHR-wt. The allelic variation mutant eFSHR-A306T was not found to affect the basal cAMP response or half maximal effective concentration (EC₅₀) levels. On the other hand, eFSHR-D566G and eFSHR-A306T displayed a 1.5- and 1.4-fold increase in the maximal response, respectively. Signal transduction was found to be completely impaired in case of the inactivating mutants eFSHR-A189V, -R572C, and -A574V. When compared with eFSHR-wt, eFSHR-N191I displayed a 5.4-fold decrease in the EC₅₀ levels (3,910 ng/mL) and a 2.3-fold decrease in the maximal response. In contrast, cells expressing eFSHR-R633H displayed in a similar manner to that of the cells expressing the eFSHR-wt on signal transduction and maximal response. Conclusion: The activating mutant eFSHR-D566G greatly enhanced the signal transduction in response to FSH, in the absence of agonist treatment. We suggest that the state of activation of the eFSHR can modulate its basal cAMP accumulation.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2005.06a
• /
• pp.1745-1748
• /
• 2005

According to the demand of the high productivity, the interest of manufacturing skills is growing in industrial society. Especially the high speed spindle in machining center becomes important these days. The exchange time of the tool in machining center usually calls T-T(tool to tool) time. Detailly explaning, It is influenced by the unclamping time. Affecting factors of the unclamping time are various(the hydraulic system, drawbar mass, a flow meter, disc spring, a piston diameter, pipe diameters, and so on). In this study, we could find factors that decrease the unclamping time and verify it for softwares.(AMESim $4.0^{(R)}$ & visual Nastran $4D^{(R)}$)

• Journal of Animal Science and Technology
• /
• v.46 no.6
• /
• pp.917-924
• /
• 2004

Using PCR-RFLP haplotyping for the mitochondrial DNA(mtDNA) fragment containing the NADH dehydrogenase 2 gene(ND2) and three tRNA genes(tRNA-Met, tRNA-Trp and tRNA-Ala), we characterized the genetic diversity of five pig breeds including Jeju native pigs. mtDNA polymorphisms showing distinct cleavage patterns were found in the pig breeds. Two digestion patterns were detected when HaeIII- and Hinfl-RFLP, and four in the Tsp5091-RFLP analyses. Combining the three restriction enzyme digestion patterns found in five different pig breeds, four mtDNA haplotypes were observed and the haplotype frequencies were significantly different by the pig breeds. A monomorphic haplotype, mtWB, was observed in both Korean wild boars and Large White pigs. Both Duroc and Landrace pigs contained two haplotypes suggesting their multiple maternal lineages. Jeju native pig has two haplotypes(mtJN and mtJD). Of these, mtJN is identified as a Jeju native pig specific haplotype. This study suggested that more than two progenitor populations have been taken part in the domestication process of the Jeju native pig population, and/or probably subsequent crossing with other pig breeds from near east Asia. Unlike with our prediction, there was no direct evidence under molecular levels on the maternal introgression of Korean wild boar in the domestication of Jeju native pigs. In conclusion, specificity of mtDNA haplotypes related to pig breeds win be useful for identifying the maternal lineage as wen as constructing the genealogical pedigree in pigs.

• Nuclear Engineering and Technology
• /
• v.41 no.2
• /
• pp.155-162
• /
• 2009

Since the 90's, EDF and AREVA-NP have irradiated, up to very high burnups, lead assemblies housing $M5^{(R)}$ cladded fuels. Post-irradiation examination of high burnup $UO_2$ pellets show an increase in the fission-gas release rate, an increase in fuel swelling, and formation of fission-gas bubbles throughout the pellets. Xenon abundances were quantified, and phenomena leading to this bubble formation were identified. All examinations provided valuable data on the complex state of the fuel during irradiation. They show the good behavior of these fuels, exhibiting various microstructures at very high burnups, none of which is likely to lead to problems during irradiation.

• Bulletin of the Korean Mathematical Society
• /
• v.57 no.4
• /
• pp.991-1002
• /
• 2020

We show that when n > m, the following delay differential equation fⁿ(z)f'(z) + p(z)(f(z + c) - f(z))^m = r(z)e^q(z) of rational coefficients p, r doesn't admit any transcendental entire solutions f(z) of finite order. Furthermore, we study the conditions of α₁, α₂ that ensure existence of transcendental meromorphic solutions of the equation fⁿ(z) + f^n-2(z)f'(z) + P_d(z, f) = p₁(z)e^α₁(z) + p₂(z)e^α₂(z). These results have improved some known theorems obtained most recently by other authors.

• Bulletin of the Korean Chemical Society
• /
• v.8 no.1
• /
• pp.1-3
• /
• 1987

The crystal structure of $K_5Na_2[SbW_6O_{24}]{\cdot}12H_2O$ has been determined. Final R = 0.081 for 890 observed independent reflections collected by diffractometry. Crystal data as follows; trigonal, space group R3m, a = 9.794(1) ${\AA},\;{\alpha}$ = 84.72$(1)^{\circ}$, Z = 1. The heteropolyanion has a structure with point symmetry $D_{3d}$ (3m), of the ideal Anderson-type heteropolyanion. The Sb-W and W-W distances are 3.259(2) and 3.259(3) ${\AA}$. Three types of W-O ($W-O_t,\;W-O_b\;and\;W-O_c$) distances are 1.73(2), 1.95(4) and 2.20(3) ${\AA}$. The Sb-O distance is 1.97(3) ${\AA}$.

• Journal of the Korean Ceramic Society
• /
• v.40 no.2
• /
• pp.139-145
• /
• 2003

We studied oxidation behaviors of anti-oxidative Y-Cr oxide coated sol on ferritic steel for application of the Fe-Cr alloys as interconnectors of planar-type Solid Oxide Fuel Cells(SOFCs). In coated$YCrO_3$on the ferritic steel, the phases of $YCrO_3$,$Cr_2O_3$and $Mn_{1.5}Cr_{1.5}O_4$on the coated surface were detected, but iron base scales were not observed after oxidation at 80$0^{\circ}C$ for 40 h. The Mn-Cr oxide scales were grown with oxidation by diffusing components in the ferritic steel from inner. The Log(ASR/T) value that expresses electrical resistance of coated$YCrO_3$on the ferritic steel was -4.57~$-4.70{omega}cm^2K^{-1}$, lower in comparison with the one of the uncoated ferritic steel,$-3.99{omega}cm^2K^{-1}$. This indicates the applicability of Fe-l6Cr alloy as interconnector materials for SOFCs.