• Title/Summary/Keyword: C.M.R.T.

Search Result 1,173, Processing Time 0.034 seconds

The effect of glutathione S-transferase M1 and T1 polymorphisms on blood pressure, blood glucose, and lipid profiles following the supplementation of kale (Brassica oleracea acephala) juice in South Korean subclinical hypertensive patients

  • Han, Jeong-Hwa;Lee, Hye-Jin;Kim, Tae-Seok;Kang, Myung-Hee
    • Nutrition Research and Practice
    • /
    • v.9 no.1
    • /
    • pp.49-56
    • /
    • 2015
  • BACKGROUND/OBJECTIVES: Glutathione S-transferase (GST) forms a multigene family of phase II detoxification enzymes which are involved in the detoxification of reactive oxygen species. This study examines whether daily supplementation of kale juice can modulate blood pressure (BP), levels of lipid profiles, and blood glucose, and whether this modulation could be affected by the GSTM1 and GSTT1 polymorphisms. SUBJECTS/METHODS: 84 subclinical hypertensive patients showing systolic BP over 130 mmHg or diastolic BP over 85 mmHg received 300 ml/day of kale juice for 6 weeks, and blood samples were collected on 0-week and 6-week in order to evaluate plasma lipid profiles (total cholesterol, triglyceride, HDL-cholesterol, and LDL-cholesterol) and blood glucose. RESULTS: Systolic and diastolic blood pressure was significantly decreased in all patients regardless of their GSTM1 or GSTT1 polymorphisms after kale juice supplementation. Blood glucose level was decreased only in the GSTM1-present genotype, and plasma lipid profiles showed no difference in both the GSTM1-null and GSTM1-present genotypes. In the case of GSTT1, on the other hand, plasma HDL-C was increased and LDL-C was decreased only in the GSTT1-present type, while blood glucose was decreased only in the GSTT1-null genotype. CONCLUSIONS: These findings suggest that the supplementation of kale juice affected blood pressure, lipid profiles, and blood glucose in subclinical hypertensive patients depending on their GST genetic polymorphisms, and the improvement of lipid profiles was mainly greater in the GSTT1-present genotype and the decrease of blood glucose was greater in the GSTM1-present or GSTT1-null genotypes.

The Local Scour around Submarine Pipelines in the Interaction Region Combined with Waves and Currents (파랑과 정상흐름의 공존역에서 해저관로 주변의 국부세굴)

  • Kim, Kyoung-Ho;Lee, Ho-Jin;Kim, Wan-Shik
    • Journal of Korean Society of Coastal and Ocean Engineers
    • /
    • v.20 no.5
    • /
    • pp.510-521
    • /
    • 2008
  • In the study, experiments are performed in the interaction region combined with wave and current to investigate the characteristics of local scour around submarine pipelines. Wave generator and current generator are used for the experiments and two current directions were used; co-direction and counter direction to the wave. The local scour depths around the pipeline are obtained according to the various pipe diameters(D), wave periods(T), wave heights(H), and current velocities(V). The experiments show that the maximum equilibrium local scour depth increases with pipe diameter, wave period, wave height, and current velocity. Using the experimental results, the correlations of scour depth and parameters such as Shields parameter($\theta$), Froude number(Fr), period parameter, Keulegan-Carpenter number(KC), Ursell number($U_R$), modified Ursell number($U_{RP}$) and ratio of velocities($U_{c}/(U_{c}+U_{m})$) are analyzed. In the interaction region combined with waves and currents, Froude number and Shields parameter are found the main parameters to cause the local scour around the submarine pipelines and this means that current governs the scour within any limits of the currents.

Studies on Piroplasmosis Infection and Morphological Development of Piroplasma in Experimental Animals (피로풀라스마병(病)에 관(關)한 연구(硏究) 실험동물(實驗動物)에 대(對)한 감염시험(感染試驗) 및 그 형태학적(形態學的) 변화(變化)에 대(對)하여)

  • Han, T.W.
    • Korean Journal of Veterinary Research
    • /
    • v.8 no.2
    • /
    • pp.98-109
    • /
    • 1968
  • The small type piroplasma which is known to be prevailing in Korean cattle was injected to un-susceptible hosts such as mice, guinea pigs, rats, rabbits, fowls and developing chicken eggs by i.v., i.p, and intra C.A.M. routes, and its morphological development in each animal species was observed. 1. The small type piroplasma of cattle did not produce any pathogenicity in the experimental animals such as mice, guinea pigs, rats, rabbits, fowls and developing chicken embryos. However, only a partial sign for developing cycle of the organism was observed in the peritoneal fluid. The schizogony of protozoa was not detected in any organs of the inoculated animals. 2. In the animals inoculated, the parasites of I-III types, relative to the process of time in the host, have changed their shapes into IV-VI types and then VI-X types however, the type X was not restored to the type I. In guinea pigs, more grape type was detected then X type in number, and in process of time, the shape was changed from round to elliptic, and the pointed end of the organism appeared in flesh color. 3. None of the organisms were found from the blood stream of inoculated animals excepts only a few piroplasma as were found in the experimental mice shortly after inoculation or i.v. route, No protozoa was also found in the organs of the animals autopsied. 4. The form change of protozoa was more clear in these animals than that in susceptible host. The most piroplasmas have changed their forms into VI-X types 30 hours after inoculation and were dispersed from R.B.C. Tracing of piroplasrna beyond this stage was not attempted. 5. The small type piroplasma comprises in I. X types and it is further believed that VII-X types which were freed from one cell proceeded to invade others. The from of development resembles to the small type of piroplasma which is prevailing in Japan.

  • PDF

The Formation of $YBa_2Cu_3O_{7-x}$(Y123) and CuO Phases in Cu-sheath YBCO Thick Films (동피복 YBCO 후막에서 $YBa_2Cu_3O_{7-x}$(Y123) 및 CuO상의 형성 기구)

  • Kim K.J.;Han S. C.;Han Y. H.;Jeong N. H.;Yun H. J.;Oh J. M.;Choi H. R.;Sung T. H.
    • Progress in Superconductivity
    • /
    • v.6 no.2
    • /
    • pp.129-132
    • /
    • 2005
  • The formation behavior of $YBa_2Cu_3O_{7-x}$(Y123) and CuO phases in the heat-treated Cu-sheathed YBCO thick films was studied. The thick films were prepared by screen-printing method using $BaCO_3$ and Y211 powders on Cu tapes. The screen-printed thick films were placed at the center of the tube furnace, heated to $930^{\circ}C$ in air atmosphere and then maintained at the temperature for 60 sec - 300 sec. The microstructure and phases formed in the thick films were investigated by using optical microscope, X-ray diffraction (XRD) and SEM image analysis. During the heat treatment, partial melting occurred rapidly in the printed layers by peritectic reaction between CuO and precursor powders, and then YBCO superconducting phases nucleated from the Cu tapes and grew in a form of thick films.

  • PDF

Eggshell Pigmentation Study in Blue-shelled and White-shelled Ducks

  • Liu, H.C.;Hsiao, M.C.;Hu, Y.H.;Lee, S.R.;Cheng, W.T.K.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.23 no.2
    • /
    • pp.162-168
    • /
    • 2010
  • This study attempted to clarify the difference in eggshell pigmentation between blue-shelled ducks (BSD) and whiteshelled ducks (WSD). The eggshell pigmentation deposition process is discussed. Ultraviolet spectro-photometer and HPLC were used to determine the biliverdin concentration in the shell gland, uterus liquid and eggshell at 6, 12, 18, 20, 23.5 h post-oviposition. The biliverdin concentration in the eggshell and uterus fluid showed significant differences between BSD and WSD, but not in the shell gland. The heme oxygenase activity in the shell gland of both kinds of ducks remained mostly constant during the ovulatory cycle with no variation. The assay of exogenous biliverdin injection into the shell gland antrum in the WSD indicated that exogenous biliverdin could be deposited continuously into the eggshell until the source was exhausted. A layer-by-layer dissolution assay was used to examine the eggshell pigment deposition process. The biliverdin concentration in the first to sixth layers of the eggshell in the BSD was significantly higher than that in the white-shelled counterpart. The blue pigment concentration increased persistently from the 6th layer to the $1^{st}$ layer. The BSD eggshells did not accumulate a large quantity of biliverdin in the most external layer. They tended to increase the deposition layer by layer. Our results demonstrated that different BSD and WSD eggshell colors were influenced by the amount of biliverdin in the uterus fluid and not determined by the amount of biliverdin in the shell gland. This implies the existence of a mechanism that controls biliverdin transportation from the shell gland into the uterus fluid, thereby playing a key role in regulating duck eggshell color.

Modelling Pasture-based Automatic Milking System Herds: Grazeable Forage Options

  • Islam, M.R.;Garcia, S.C.;Clark, C.E.F.;Kerrisk, K.L.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.28 no.5
    • /
    • pp.703-715
    • /
    • 2015
  • One of the challenges to increase milk production in a large pasture-based herd with an automatic milking system (AMS) is to grow forages within a 1- km radius, as increases in walking distance increases milking interval and reduces yield. The main objective of this study was to explore sustainable forage option technologies that can supply high amount of grazeable forages for AMS herds using the Agricultural Production Systems Simulator (APSIM) model. Three different basic simulation scenarios (with irrigation) were carried out using forage crops (namely maize, soybean and sorghum) for the spring-summer period. Subsequent crops in the three scenarios were forage rape over-sown with ryegrass. Each individual simulation was run using actual climatic records for the period from 1900 to 2010. Simulated highest forage yields in maize, soybean and sorghum- (each followed by forage rape-ryegrass) based rotations were 28.2, 22.9, and 19.3 t dry matter/ha, respectively. The simulations suggested that the irrigation requirement could increase by up to 18%, 16%, and 17% respectively in those rotations in El-Nino years compared to neutral years. On the other hand, irrigation requirement could increase by up to 25%, 23%, and 32% in maize, soybean and sorghum based rotations in El-Nino years compared to La-Nina years. However, irrigation requirement could decrease by up to 8%, 7%, and 13% in maize, soybean and sorghum based rotations in La-Nina years compared to neutral years. The major implication of this study is that APSIM models have potentials in devising preferred forage options to maximise grazeable forage yield which may create the opportunity to grow more forage in small areas around the AMS which in turn will minimise walking distance and milking interval and thus increase milk production. Our analyses also suggest that simulation analysis may provide decision support during climatic uncertainty.

Cloning of the non-virion (NV) of a Korean Isolate of Infectious Hematopoietic Necrosis and Identification of the Role of the NV in IHNV Replication (한국에서 분리된 전염성 조혈괴저 바이러스의 non-virion (NV) 단백질의 유전자 클로닝 및 바이러스 증식에서의 역할)

  • 문창훈;조화자;윤원준;박정재;박정민;김현주;도정완;이주양;임채렬
    • Korean Journal of Microbiology
    • /
    • v.36 no.2
    • /
    • pp.103-108
    • /
    • 2000
  • We have cloned and analyzed cDNA coding for non-virion (NV) protein of the m V - P R T The NV gene contained 336 bp open readmg frame and encoded a protein of 11 1 amino acids with a molecular weight of 13.2 kDa. The deduced amino acid sequence of NV of IHNVPRT was found to be 90-95% identical to those of foreign isolates of IHNV. These results indicate that NV gene of the MNV is highly conserved among &ifferent strains of THNV Northern blot analyses revealed that the levels of NV gene expression were strongly elevated after 20 h post-infection. In order to identify the role of NV in the replication of MNV in fish cells, IHNVinfected cells were treated with antisense oligonucleotides. While IHNV-PRT exposed to glycoprotein (G) antisense oligonucleotide showed severely reduced growth, the growth of virus exposed to NV antisense oligonucleotide was not affected by NV antisense oligonucleotide, which suggests that NV is not essential for replication of IHNV in fish cells.

  • PDF

THE BIMA PROJECT: O-C DIAGRAMS OF ECLIPSING BINARY SYSTEMS

  • HAANS, G.K.;RAMADHAN, D.G.;AKHYAR, S.;AZALIAH, R.;SUHERLI, J.;IRAWATI, P.;SAROTSAKULCHAI, T.;ARIFIN, Z.M.;RICHICHI, A.;MALASAN, H.L.;SOONTHORNTHUM, B.
    • Publications of The Korean Astronomical Society
    • /
    • v.30 no.2
    • /
    • pp.205-209
    • /
    • 2015
  • The Eclipsing Binaries Minima (BIMA) Monitoring Project is a CCD-based photometric observational program initiated by Bosscha Observatory - Lembang, Indonesia in June 2012. Since December 2012 the National Astronomical Research Institute of Thailand (NARIT) has joined the BIMA Project as the main partner. This project aims to build an open-database of eclipsing binary minima and to establish the orbital period of each system and its variations. The project is conducted on the basis of multisite monitoring observations of eclipsing binaries with magnitudes less than 19 mag. Differential photometry methods have been applied throughout the observations. Data reduction was performed using IRAF. The observations were carried out in BVRI bands using three different small telescopes situated in Indonesia, Thailand, and Chile. Computer programs have been developed for calculating the time of minima. To date, more than 140 eclipsing binaries have been observed. From them 71 minima have been determined. We present and discuss the O-C diagrams for some eclipsing binary systems.

The effect of Attrition milling and calcining temperature on the microstructure and electrical properties of non-reduction PTCR-$BaTiO_3$ Ceramics (내환원 $BaTiO_3$ 세라믹스의 PTCR특성 및 미세구조에 대한 Attrition milling과 하소온도가 미치는 영향)

  • Lee, Jeong-Cheol;Myoung, Seong-Jae;Chun, Myoung-Pyo;Cho, Jeong-Ho;Kim, Byung-Ik;Sin, Dong-Wook
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • 2007.06a
    • /
    • pp.288-288
    • /
    • 2007
  • 본 연구에서 내환원성 $BaTiO_3$의 PTCR(Positive Temperation Coefficient Resistance) 특성 및 미세구조에 대한 분쇄 및 출발 원료들의 하소 조건의 영향을 연구하였다. $BaCO_3$, $TiO_2$, $CeO_2$를 Attrition milling 하여 1차 혼합 및 분쇄한 후 건조하여 혼합분말을 얻었으며, $(Ba_{1-x}Ce_x)TiO_3$를 합성하기 위하여 $1000^{\circ}C{\sim}1200^{\circ}C$ 공기중에서 하소하였다. 각 하소온도에서 제조한 $(Ba_{1-x}Ce_x)TiO_3$에 첨가제를 2차 혼합하고 초미분쇄하여 분말을 제조하였다. 직경 5mm 의 시편을 제조하여 환원 및 재산화 분위기에서 소결을 한 후 상온저항값 및 R-T특성을 측정하였고 SEM 을 통해 미세구조를 관찰하였다. 또한 하소 후 온도에 따른 상분석을 XRD를 통하여 분석하였다. 그 결과 하소온도가 증가함에 따라 상온저항값은 감소하는 경황을 보였으며 PTC특성은 감소하다가 증가하는 경향을 보였다. 초미분쇄에 따른 입자크기는 $1{\mu}m$이하로 작아졌으며 미립화가 됨에 따라 하소/소결온도에 앙향을 줄 것으로 사료된다.

  • PDF

Depressive Symptoms in Newly Diagnosed Lung Carcinoma: Prevalence and Associated Risk Factors

  • Shahedah, K.K.;How, S.H.;Jamalludin, A.R.;Mohd Faiz, M.T.;Kuan, Y.C.;Ong, C.K.
    • Tuberculosis and Respiratory Diseases
    • /
    • v.82 no.3
    • /
    • pp.217-226
    • /
    • 2019
  • Background: Depression is a recognized complication of lung cancer underreported in developing countries such as Malaysia. Treating and identifying depression in cancer patients increases survival and quality of life. Our objectives are to study prevalence of depressive symptoms in newly diagnosed lung carcinoma, and examine the relationship of depressive symptoms with other influencing risk factors. Methods: A 2-year, cross sectional study February 2015-February 2017, was conducted at Hospital Tengku Ampuan Afzan, and Penang General Hospital. One hundred and three patients with newly diagnosed, biopsy confirmed primary lung carcinoma were recruited. Self-rated patient's identification sheet, validated Center for Epidemiologic Studies Depression (CES-D), and Dukes University Religion Index score from three different main languages were used. Results: Prevalence of current depressive symptoms (CES-D total score ${\geq}16$) is 37.9%. The result suggests prevalence of those at high risk of moderate to major depression, may need treatment. Multivariate analysis reveals those with good Eastern Cooperation Oncology Group factor (${\eta}2=0.24$, p<0.001) married (${\eta}2=0.14$, p<0.001) with intrinsic religiosity (IR) (${\eta}2=0.07$, p<0.02) are more resistant to depression. Conclusion: One in three of lung carcinoma patients, are at increased risk for depression. Clinicians should be aware that risk is highest in those with poor performance status, single, and with poor IR. We suggest routine screening of depression symptoms as it is feasible, to be performed during a regular clinic visit with immediate referral to psychiatrist when indicated.