• 핵의학기술
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• 제23권1호
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• pp.69-74
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• 2019

$^{18}F$-FDOPA는 뇌 종양의 아미노산 대사를 추적하는 방사성 의약품이다. 본 연구의 목적은 뇌 종양의 아미노산 대사를 영상화 하여 악성 종양을 진단하는 $^{18}F$-FDOPA와 포도당 대사를 통한 $^{18}F$-FDG의 Brain PET/CT 검사 영상의 대조도 분석을 통해 병변의 검출 능력을 비교하고, $^{18}F$-FDOPA Brain PET/CT 검사에서 섭취 시간에 따른 SUV의 변화를 분석하여 최적의 영상 획득 시간을 알아보기 위함이다. $^{18}F$-FDOPA 와 $^{18}F$-FDG 두 영상에서 종양(Tumor)과 소뇌(Cerebellum)의 중심에 각각 약 $350mm^2$의 관심 영역을 설정하여 $SUV_{max}$를 측정하였고, 종양과 소뇌의 $SUV_{max}$ 비율(T/C ratio)을 산출하였고, $^{18}F$-FDOPA 투여 직후 30분 동안 획득한 리스트 수집 방식 데이터(List mode data)를 활용해 2분씩 15프레임으로 나눈 뒤 각 프레임 별로 종양과 소뇌 중심에 $SUV_{max}$를 측정하여 위와 동일한 방법으로 T/C ratio를 산출하여 분석하였다. 종양의 평균 $SUV_{max}$를 비교해 본 결과, $^{18}F$-FDOPA Brain PET/CT 검사에서 $4.2{\pm}0.8$, $^{18}F$-FDG Brain PET/CT 검사에서는 $5.6{\pm}0.7$ 이었다. 또한, T/C ratio는 $^{18}F$-FDOPA 검사에서 $2.1{\pm}0.7$, $^{18}F$-FDG 검사에서는 $1.1{\pm}0.4$ 이었으며, $^{18}F$-FDOPA의 $SUV_{max}$는 $^{18}F$-FDG보다 낮지만 T/C ratio는 높게 나타나 종양 구별 능력이 더욱 뛰어난 것을 알 수 있었다(t=-5.214, p=0.000). $^{18}F$-FDOPA의 섭취 시간에 따른 $SUV_{max}$와 T/C ratio를 분석한 결과, $SUV_{max}$와 T/C ratio의 Peak는 모두 6~8분에서 나타났다. 이를 토대로 본원에서 $^{18}F$-FDOPA Brain PET/CT 검사에서 활용하는 10~30분의 영상과 Peak가 나타나기 시작한 6~26분의 영상을 비교한 결과 SUV와 T/C ratio가 각각 0.2, 0.1 증가하였다. 추후 지속적인 연구를 통해 검사 소요시간의 단축 가능성과 추가적인 스캔 정보 활용을 통한 정확한 진단에도 도움이 될 것으로 사료된다.

• 한국항행학회논문지
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• 제18권4호
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• pp.304-311
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• 2014

본 논문에서는 항공기 복합재료 내부의 결함을 자동으로 검출하고 분류하는 초음파 검사 방식을 제안한다. 결함 검출을 위해서 초음파의 국부 최대값을 이용해 피크(peak) 값을 추출해낸다. 피크의 거리정보를 이용해 히스토그램화 하며 시편의 표면과 바닥의 백월에코(back-wall echo)를 결정한다. 이를 통해 C-scan 영상을 생성한다. 검출된 피크의 평균과 분산을 이용해 임계값을 정하고 그 값으로 결함여부를 판단한다. 결함의 종류를 구분하기 위해서는 주성분 분석(PCA; principal component analysis)와 이차 판별 분석(QDA; quadratic discriminant analysis)를 수행하였다. PCA를 통한 512개의 차원은 주성분으로 변환 시 30개의 주성분에 99% 이상의 분산이 포함되었다. 주성분 개수를 한정시킴으로써 차원 축소를 통해 계산량을 크게 줄였고 오분류를 최소화하였다. 이차 판별 분석을 적용해 결정경계(decision boundary)의 방정식을 얻었고 이를 통해 결함을 분류할 수 있음을 실험을 통해 보였다.

• 대한기계학회논문집A
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• 제27권2호
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• pp.317-326
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• 2003

The influence of cyclic bending moment on the delamination and the fatigue crack propagation behavior in Al/GFRP laminate such as the wing section was investigated. The main objective of this study was to evaluate the relationship between crack profile and delamination behavior. And a propose parameter on the delamination growth rate(d $A_{D}$/da) of Al/GFRP laminates with a saw-cut using relationship between delamination area( $A_{D}$) and cycles(N), crack length(a), stress intensity factor range($\Delta$K). Also, the fiber bridging effect factor( $F_{BE}$ ) was propose that the fiber bridging modification factor($\beta$$_{fb}$ ) to evaluate using the delamination growth rate(d $A_{D}$/da). The shape and size of the delamination zone formed along the fatigue crack between aluminum alloy sheet. Class fiber-adhesive layer were measured by an ultrasonic C-scan image. The shape of delamination zone turns out to be semi-elliptic with the contour decreased non-linearly toward the crack tip. It represents that relationship between crack length and delamination growth rate(d $A_{D}$/da) were interdependent by reciprocal action, therefore it's applicable present a model for the delamination growth rate(dA/sib D//da) in Al/GFRP laminates.minates.s.

• Composites Research
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• 제23권6호
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• pp.1-6
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• 2010

복합재 항공기 동체의 낙뢰손상방지를 목적으로 탄소섬듐-주석 산화물(ITO) 나노입자를 코팅함으로써 탄소섬유강화플라스틱(CFRP) 복합재료의 전기전도도를 향상하였다. 탄소섬유에 코팅된 ITO 나노입자는 10~40%의 농도로 콜로이드 상태에서 분사되었다. CFRP의 전기전도도는 코팅 후 3배 이상 증가하였으며 현재 B-787 복합재 항공기 동체에 사용 중인 기술인 금속메쉬를 CFRP 외층에 매몰한 경우보다도 높은 전기전도도를 얻을 수 있었으며, 나노입자 코팅으로 섬유-기지 계면에 미지는 악영향은 발견되지 않았다. 모의 낙뢰에 의한 손상영역은 각각 다른 처리를 한 재료와 조건에 따라 초음파 C-scan 이미지로 확인하였다. ITO 40% 코팅 시편의 경우 전기전도도는 B-787 샘플의 경우보다 높았지만 낙뢰에 의한 손상영역의 크기는 거의 비슷한 수준이었다.

• IUGG한국위원회:학술대회논문집
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• IUGG한국위원회 2003년도 정기총회 및 학술발표회
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• pp.14-14
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• 2003

SAR (Synthetic Aperture Radar) is an imaging radar which can scan and image Earth System targets without solar illumination. Most Earth observation Shh systems operate in X-, C-, S-, L-, and P-band frequencies, where the shortest wavelength is approximately 1.5 cm. This means that most opaque objects in the SAR signal path become transparent and SAR systems can image the planetary surface targets without sunlight and through rain, snow and/or even volcanic ash clouds. Most conventional SAR systems in operation, including the Canada's RADARSAT-1, operate in one frequency and in one polarization. This has resulted in black and with images, with which we are familiar now. However, with the launching of ENVTSAT on March 1 2002, the ASAR system onboard the ENVISAT can image Earth's surface targets with selected polarimetric signals, HH+VV, HH+VH, and VV+HV. In 2004, Canadian Space Agency will launch RADARSAT-II, which is C-band, fully polarimetric HH+VV+VH+HV. Almost same time, the NASDA of Japan will launch ALOS (Advanced land Observation Satellite) which will carry L-band PALSAR system, which is again fully polarimetric. This means that we will have at least three fully polarimetric space-borne SAR system fur civilian operation in less than one year. Are we then ready for this new all weather Earth Observation technology\ulcorner Actual imaging process of a fully polarimetric SAR system is not easy to explain. But, most Earth system scientists, including geologists, are familiar with polarization microscopes and other polarization effects in nature. The spatial resolution of the new generation of SAR systems have also been steadily increased, almost to the limit of highest optical resolution. In this talk some new applications how they are used for Earth system observation purpose.

• 핵의학기술
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• 제12권1호
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• pp.49-56
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• 2008

Purpose: Whole body imaging with radioiodine can detect functioning metastases. Non-physiologic I-131 uptake detected on images usually is interpreted as suggesting functioning thyroid metastases. However, extra-thyroidal I-131 accumulation does not always imply thyroid cancer metastases and has been reported in many circumstances. In order to avoid unnecessary therapeutic interventions it is important to distinguish false-positive sites of I-131 localization. We study here to remove false-positive sites around esophagus region on I-131 whole body imaging in patients who were administrated thyroidectomy. Materials and Methods: From April to August in 2007, we had the patients who had visited our department after they received thyroidectomy due to thyroid cancer. They were given I-131, and performed radioiodine body scan after 41 to 50 hours. Patients were whole-body-scanned for the speed of 8 cm per minute. After that, we took anterior and posterior static images around the patients' neck measured by 300 thousand counts per image. We selected 44 patients who had hot spots around neck region, we divided the patients into two groups. One group was given 0.5 L of water and the other group was given 0.5 L of water with 1 g of Vitamin C dissolved. The patients were asked to drink the fluid for one minute in sitting position and after that, we measured 300 kilo counts per image again. We compared prior anterior, posterior static images with anterior, posterior images after the patients had water or water that Vitamin C resolved. Results: In using water, both observer 1 and 2 interpreted 6 patients were washed out. In the water with Vitamin C resolved, observer 1 and 2 interpreted 9 and 8 patients were washed out. Observer 1 and 2 interpreted 6 and 5 patients had 'indeterminate' when they used water. Both observer 1 and 2 interpreted 6 patients had 'indeterminate' when they used water with Vitamin C resolved. When they used water, observer 1 interpreted 10 patients had 'unchanged' and observer 2 interpreted 11 patients had 'unchanged'. Differently, when they used water with vitamin C resolved, observer1 had 8 patients having 'unchanged'and observer 2 had 9. Conclusion: As a result, by making patients drink 0.5 liter of water which has vitamin C resolved helped getting rid of false-positive sites in esophagus. Therefore, based on this study, we believe that drinking water with vitamin C dissolved is very in terms of reducing false-positive hot spot around the esophagus for the iodine-131 whole body scan.

• 한국콘텐츠학회논문지
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• 제11권12호
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• pp.814-821
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• 2011

256 다중 검출기 전산화단층촬영 (multi detector computed tomography, MDCT)에서 두개부 전용 팬톰을 이용하여 분해능 파라메터와 재구성 필터의 영상 품질을 평가하고자 하였다. 사용한 장비는 256 MDCT 을 사용하였으며 philips system head phantom을 이용하여 Extended Brilliance Workspace에서 영상의 질 평가를 측정하였다. 장비에서 지원하고 있는 분해능 파라메터와 재구성 필터가 화질에 미치는 영향을 알아보기 위해서 검사조건을 $512{\times}512$ matrix, $128{\times}0.625$ mm beam collimation, 120 kVp, 250 mAs, 0.5 sec, 250 mm field of view (FOV), 절편 두께와 절편 간격은 5 mm, 1.0 pitch로 동일하게 적용하였다. 분해능 파라메터은 'Standard', 'High', 'Ultrahigh'로 구분하여 적용하였으며, 재구성 필터는 'A', 'B', 'C', 'D', 'UA', 'UB', 'UC' 등으로 바꿔가면서 영상을 재구성하여 노이즈, 균일도, 직선성, 변조전달함수 (modulation transfer function, MTF)의 50%와 10%를 측정하였다. 그 결과 'High' 분해능은 균일도, 직선성, MTF 50%와 10%에서 우수하였다. 'UA', 'UB' 재구성 필터는 균일도와 노이즈 평가에서 양호했으며 'C'재구성 필터는 직선성과 MTF 50%와 10%에서 양호하였다.

• 대한의용생체공학회:의공학회지
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• 제33권2호
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• pp.72-77
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• 2012

Phase Contrast MR Angiography(PC MRA) is excellent MRA technique for measuring the velocity of vessels in the human body. PC MRA need to at least four images for angiogram reconstruction and it caused longer scan time. Therefore, we used keyhole imaging combined PC MRA to reduce the scan time. However, keyhole imaging can lead the erroneous effects as loss of phase information or frequency discontinuous. In this study, we applied the keyhole imaging combined 2D PC MRA for improving the temporal resolution and also measured the velocity to evaluate the accuracy of phase information. We used 0.32T MRI scanner(Magfinder II, Scimedix, Korea). Using the 2D PC MRA pulse sequence, the vascular images for a human brain targeted on the Superior Sagittal Sinus(SSS) were obtained. We applied tukey window function for keyhole images to minimize the ringing artifact and erroneous factors that are induced frequency discontinuous and phase information loss. We also applied zero-padded algorithm to peripheral missing k-space lines to compare keyhole imaging results and the artifact power(AP) value was measured on the complex difference images to validate the image quality. Consider as based on our results, heavy image distortions and artifacts were shown until using at least 50% keyhole factor. Using above the 50% keyhole factors are shown well reconstructed and matched for magnitude images and velocity information measurements. In conclusion, we confirmed the image quality and velocity information of keyhole technique combined 2D PC MRA. Especially, measured velocity information through the keyhole imaging combination was similar to the velocity information of full sampled k-space image despite of frequency discontinuous and phase information loss in the keyhole imaging reconstruction process. Consequently, the keyhole imaging combined 2D PC MRA will give some clinical usefulness and advantages as improving the temporal resolution and measuring the velocity information via selecting the appropriate keyhole factor at low tesla MRI system.

• International Journal of Computer Science & Network Security
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• 제23권11호
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• pp.183-189
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• 2023

A stroke is a medical disease where a blood vessel in the brain ruptures, causes damage to the brain. If the flow of blood and different nutrients to the brain is intermittent, symptoms may occur. Stroke is other reason for loss of life and widespread disorder. The prevalence of stroke is high in growing countries, with ischemic stroke being the high usual category. Many of the forewarning signs of stroke can be recognized the seriousness of a stroke can be reduced. Most of the earlier stroke detections and prediction models uses image examination tools like CT (Computed Tomography) scan or MRI (Magnetic Resonance Imaging) which are costly and difficult to use for actual-time recognition. Machine learning (ML) is a part of artificial intelligence (AI) that makes software applications to gain the exact accuracy to predict the end results not having to be directly involved to get the work done. In recent times ML algorithms have gained lot of attention due to their accurate results in medical fields. Hence in this work, Stroke disease identification system by using Machine Learning algorithm is presented. The ML algorithm used in this work is Artificial Neural Network (ANN). The result analysis of presented ML algorithm is compared with different ML algorithms. The performance of the presented approach is compared to find the better algorithm for stroke identification.

• 동력기계공학회지
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• 제10권4호
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• pp.5-10
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• 2006

The purpose of this study is to measure the droplet distribution and Sauter mean diameter(SMD) of biodiesel fuel, using the immersion sampling method. This method involves using an optical microscope and a CCD camera, to take an image of the droplets. These images are then measured by using a 'Sigma Scan' processing program. The results of the above experiment are summarized as followed ; (1) There can be as much as a 10% error rate when measuring the diameter of these droplets, using the image processing method and the naked eye. (2) The result of droplet size distribution test, TVO(transesterified vegetable oil) big size droplet distribution were increased at ambient pressure $6kg/cm^2$. (3) When ambient pressure increased $6kg/cm^2$ above, SMD variation of TVO and UVO(used vegetable oil) 30 are small. (4) On Rosin-Rammler analysis, droplets size distribution of UVO(used vegetable oil) 30 uniform more than TVO 20 on ambient pressure $1kg/cm^2$.