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Study of overlapping setting up of Planning Target Volume for Improving Target Coverage adjacent Organ At Risk (손상위험장기에 인접한 표적 Coverage 개선을 위한 Planning Target Volume 중복 설정에 관한 연구)

  • Lee, Jung Woong;Kim, Bo Kyum;Mun, Jun Ki;Woo, Hun;Lee, Yang Hoon;Jeon, Chang Woo;Lee, Jea Hee
    • The Journal of Korean Society for Radiation Therapy
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    • v.31 no.2
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    • pp.33-41
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    • 2019
  • Purpose: The purpose of this study is to improve the reduction of coverage of PTVs adjacent to organ at risk (OAR) by setting up overlapping Planning Target Volume (PTV) during Volumetric Modulated Arc Therapy(VMAT). Materials and Methods: In patients who received Whole Brain, Gall Bladder and Rectum radiation therapy, We compared the cover change, maximum dose, Homogenicity Index and Conformity Index of PTV and also compared the maximum dose and average dose change of Organ At Risk by organizing treatment plans that are not applied overlaped PTV and treatment plans that are applied overlaped PTV in areas where coverage is insufficient. Results: overage of treatment plans with overlapping PTVs was increased in all patients, and overall coverage was also increased in each of the four patients. The maximum dose for PTV was increased in five patients, and the Homogenicity Index and Conformity Index for all patients did not differ much. The maximum dose of the lens was increased by 1.12 times, and the maximum dose was decreased in two patients for brain stem. The mean dose of the eyeball was increased by a maximum of 1.15 times, and there was no significant difference between both parotid gland. In case of gallbladder cancer patients, the mean dose in the liver and colon was decreased, and the mean dose in the duodenum was increased. In the case of rectal cancer patients, the mean dose was reduced for both femur and bladder set as OARs. The overall MU was shown to be similar in four patients, excluding one. Conclusion: If the critical dose of OAR is considered and used properly, I think it is a useful way to improve coverage of PTV.

A Comparative Study on the Electrophysiological Properties of Medial and Lateral Spinoreticular Tract Cells in Cats (고양이의 내측 및 외측 척수망상로 세포의 전기생리학적 비교연구)

  • Lee, Suk-Ho;Jun, Jae-Yeol;Park, Choon-Ok;Goo, Yong-Sook;Kim, Jun;Sung, Ho-Kyung
    • The Korean Journal of Physiology
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    • v.24 no.1
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    • pp.181-194
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    • 1990
  • Antidromically activated spinoreticular tract (SRT) cell units in the lumbosacral enlargement of ${\alpha}-chloralose$ anesthetized cats were classified as medial and lateral SRT units according to the location of their axonal termination. Identified SRT units were tested fer antidromic conduction velocity, laterality of their axonal projection, the location in spinal gray, peripheral receptive field, the response pattern to graded mechanichal stimulation and the responsiveness to $A{\delta}$ and C volley of the peripheral nerve. 1) The 59% of 34 medial SRT units were recorded in ipsilateral side to the antidromic stimulation site, but 60% of the 47 lateral SRT units projected to contralateral side. 2) Most of the medial SRT cells and rostral ventrolateral medulla (RVLM)-projecting lateral SRT cells were recorded in lamina VII & VIII. The LRN (lateral reticular nucleus)-projecting SRT cells, however, distributed through all the laminae except superficial ones (I & II). 3) The identified SRT units were classified as low theshold (LT), deep, high threshold (HT), wide dynamic range (WDR) cells, based on the response patterns to graded mechanical stimuli. The proportion of SRT units which receive noxious input was 37.5%, 25% and 75% in the medial, LRN-projecting and RVLM SRT group, respectively. 4) There was no significant difference in the mean conduction velocities between the 3 groups. But the deep cells had significantly higher velocity than that of the HT cells. The above results show that the peripheral inputs to the SRT units are different in the 3 groups: medial, LRN & RVLM SRT group. Especially in case of the SRT cells projecting to RVLM which is a probable candidate fur the integration center of various pressor reflexes such as somatosympathetic reflex, the noxious informations occupy higher proportion of input to them than in other groups. Therefore the noxious information transmitted through the lateral SRT destined for RVLM is expected to play a role in somatosymapthetic reflex.

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Effects of Electrolytes and Drugs on the Inhibitory Junction Potentials Recorded from the Antrum of Guinea-pig Stomach (기니피그 유문동에서 기록되는 억제성 접합부 전압에 미치는 전해질과 약물의 효과)

  • Goo, Yong-Sook;Suh, Suk-Hyo;Lee, Suk-Ho;Hwang, Sang-Ik;Kim, Ki-Whan
    • The Korean Journal of Physiology
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    • v.24 no.1
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    • pp.1-13
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    • 1990
  • The effects of electrolytes, adenosine, ATP, 5-hydroxytryptamine (5-HT, serotonin) and ketanserin on the inhibitory junction potentials (IJPs) were investigated to clarify the interactions of these drugs with the neurotransmitters released from non-adrenergic, non-cholinergic nerves in the antrum of guinea-pig stomach. Electrical responses of antral circular muscle cells were recorded intracellularly using glass capillary microelectrode filled with 3 M KCI. All experiments were performed in Tris-buffered Tyrode soluition which was aerated with 100% $O_{2}$ and kept at $35^{\circ}C$. The results obtained were as follows: 1) Inhibitory junction potential (IJP) was recorded in antral strip, while excitatory junction potential (EJP) was recorded in fundic strip. 2) IJP recorded in antral strip was not influenced by atropine $(10^{-6}\;M)$ and guanethidine $(5{\times}10^{-6})$. 3) The amplitude of IJP increased in high $Ca^{2+}$ solution, while that of IJP decreased in high $Mg^{2+}$ solution or by $Ca^{2+}$ antagonist (verapamil). Apamin, $Ca^{2+}$-activated $K^{+}$ channel blocker blocked IJP completely. 4) ATP and adenosine decreased the amplitude of IJP. 5) 5-HT decreased the amplitude of IJP with no change of the amplitude of slow waves, while ketanserin (5-HT type 2 blocker) decreased the amplitude of slow waves markedly with no change in that of IJP. From the above results, the following conclusions could be made. 1) IJP recorded in antral strip is resulted from neurotransmitters released from non-adrenergic, non-cholinergic nerves. 2) An increase in the concentration of external $Ca^{2+}$ enhances the release of neurotransmitters from non-adrenergic, non-cholinergic nerves which activate the $Ca^{2+}$-dependent $K^{+}$ channel.

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Fusarium moniliforme Detected in Seeds of Corn and Its Pathological Significance (옥수수 종자(種子)에서 검출(檢出)된 Fusarium moniliforme와 그 병리학적(病理學的) 중요성(重要性))

  • Kim, Wan-Gyu;Oh, In-Seok;Yu, Seung-Hun;Park, Jong-Seong
    • The Korean Journal of Mycology
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    • v.12 no.3
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    • pp.105-110
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    • 1984
  • Seven seed samples of corn obtained from Kangweon Provincial Office of Rural Development, Kerea were tested for seed-borne fungi, and found that all the samples tested were infected with Fusarium moniliforme to an extent of $6.0{\sim}79.5%$. Severely infected seed samples showed poor germination on blotter. Seed component plating showed that the fungus present not only in tip caps, pericarps and endosperms, but also in embryos. Heavy infection of the fungus caused severe seed rot and seedling blight in soil, but the damage was not severe and many plants grew without any symptoms when the seeds with light infection were sown in soil. However the fungus was frequently detected from inside of the stems of healthy looking seedlings. The results indicate that the fungus transmit from seed to plant systemically. In inoculation experiments, the fungus produced stem rots on corn plants of 110 days old. The cultivar of Hwangok 3 was revealed more susceptible to the fungus than that of Suweon 19.

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Neural pathway innervating ductus Deferens of rats by pseudorabies virus and WGA-HRP (흰쥐에서 WGA-HRP와 pseudorabies virus를 이용한 정관의 신경로에 대한 연구)

  • Lee, Chang-Hyun;Chung, Ok-Bong;Ko, Byung-Moon;Lee, Bong-Hee;Kim, Soo-Myung;Kim, In-Shik;Yang, Hong-Hyun
    • Korean Journal of Veterinary Research
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    • v.43 no.1
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    • pp.11-24
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    • 2003
  • This experimental studies was to investigate the location of PNS and CNS labeled neurons following injection of 2% WGA-HRP and pseudorabies virus (PRY), Bartha strain, into the ductus deferens of rats. After survival times 4-5 days following injection of 2% WGA-HRP and PRV, the rats were perfused, and their brain, spinal cord, sympathetic ganglia and spinal ganglia were frozen sectioned ($30{\mu}m$). These sections were stained by HRP histochemical and PRY inummohistochemical staining methods, and observed with light microscope. The results were as follows ; 1. The location of sympathetic ganglia projecting to the ductus deferens were observed in pelvic ganglion, inferior mesenteric ganglion and L1-6 lwnbar sympathetic ganglia. 2. The location of spinal ganglia projecting to the ductus deferens were observed in T13-L6 spinal ganglia. 3. The PRY labeled neurons projecting to the ductus deferens were observed in lateral spinal nucleus, lamina I, II and X of cervical segments. In thoracic segments, PRY labeled neurons were observed in dorsomedial part of lamina I, II and III, and dorsolateral part of lamina IV and V. Densely labeled neurons were observed in intermediolateral nucleus. In first lumbar segment, labeled neurons were observed in intermediolateral nucleus and dorsal commisural nucleus. In sixth lumbar segment and sacral segments, dense labeled neurons were observed in sacral parasympathetic nuc., lamina IX and X. 4. In the medulla oblongata, PRV labeled neurons projecting to the ductus deferens were observed in the trigeminal spinal nuc., A1 noradrenalin cells/C1 adrenalin cells/caudoventrolateral reticular nuc., rostroventrolateral reticular nuc., area postrema, nuc. tractus solitarius, raphe obscurus nuc., raphe pallidus nuc., raphe magnus nuc., parapyramidal nuc., lateral reticular nuc., gigantocellular reticular nuc.. 5. In the pons, PRV labeled neurons projecting to the ductus deferens were ohserved in parabrachial nuc., Kolliker-Fuse nuc., locus cooruleus, subcooruleus nuc. and AS noradrenalin cells. 6. In midbrain, PRV labeled neurons projecting to the ductus deferens were observed in periaqueductal gray substance, substantia nigra and dorsal raphe nuc.. 7. In the diencephalon, PRV labeled neurons projecting to the ductus deferens were observed in paraventricular hypahalamic nuc., lateral hypothalamic nuc., retrochiasmatic nuc. and ventromedial hypothalamic nuc.. 8. In cerebrum, PRV labeled neurons projecting to the ductus deferens were observed in area 1 of parietal cortex. These results suggest that WGA-HRP labeled neurons of the spinal cord projecting to the rat ductus deferens might be the first-order neurons related to the viscero-somatic sensory and sympathetic postganglionic neurons, and PRV labeled neurons of the brain and spinal cord may be the second and third-order neurons response to the movement of smooth muscles in ductus deferens. These PRV labeled neurons may be central autonomic center related to the integration and modulation of reflex control linked to the sensory and motor system monitaing the internal environment. These observations provide evidence for previously unknown projections from ductus deferens to spinal cord and brain which may be play an important neuroanatornical basic evidence in the regulation of ductus deferens function.

The Initial Growth of Scirpus planiculmis and its Herbicidal Response for the Screening (Screening을 위한 새섬매자기(Scirpus planiculmis) 초기생육(初期生育) 및 제초제(除草劑) 반응성(反應性))

  • Hwang, I.T.;Choi, J.S.;Lee, B.H.;Hong, K.S.;Cho, K.Y.
    • Korean Journal of Weed Science
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    • v.14 no.4
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    • pp.245-251
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    • 1994
  • The initial growth and herbicidal responses of Scirpus planiculmis were examined under both laboratory and greenhouse condition. Initial growth of S. planiculmis at two different soils(soil A and B), was compared with the growth at normal paddy soil, and growth rates at two soils were 32% and 86% as compared to the growth rates at normal paddy soil. Two different soils were soil A(rice-uncultivable) and soil B(rice-cultivable). Transplanted(2.5 leaf stage) and direct seeded rice(Dongjinbyeo) could not grow at soil A. The growth of transplanted rice at soil B was almost same as the growth at normal paddy soil, but the growth of direct seeded rice was 50% of the growth at normal paddy soil. S. planiculmis among the perennial weeds was most tolerant to NaCl, and Cyperus serotinus, Eleocharis kuroguwai, Sagittaria pygmaea, Sagittaria trifolia, Potamogeton distinctus were followed. The intial growth rate of S. planiculmis was more rapid than C. serotinus. Cutting types and times of corm reduced 20-40% of the initial growth of S. planiculmis. During the initial growth of S. planiculmis, the growth of S. planiculmis was severly inhibited by the earlier removal of corm from seedlings, and it represents that the corm plays an important role in the initial growth of this species. Bentazone among 14 commercialized herbicides showed the best safety on direct seeded rice and the highest control effect agaist S. planiculmis.

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Weed flora of agricultural area in Korea (우라나라 농경지(農耕地)의 주요(主要) 잡초분포(雜草分布) 현황(現況))

  • Kim, S.C.;Oh, Y.J.;Kwon, Y.W.
    • Korean Journal of Weed Science
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    • v.12 no.4
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    • pp.317-334
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    • 1992
  • Weed flora and floristic composition were reviewed in lowland rice field and upland crop area. For lowland rice field weed flora was not much changed since 1971. About 29 weed species belonged to 18 families were occurred. However, floristic composition of dominant weed species has greatly changed mainly due to introduction of herbicides. The predominant weed species in 1971 when herbicide was not used were Rotala indica, Eleocharis acicularis, Monochoria vaginalis, Echinochloa crus-galli, while these for in 1991 were Eleocharis kuroguwai, Sagittaria pygmaea, S. trifolia, Echinochloa crus-galli and M, vaginalis, respectively. In 1981 weed survey, E. crus-galli was no longer troblesome weed. However, this species became important again thereafter by introduction of herbicide mixtures with pyrazolate, bensulfuron-methyl or pyrazosulfuronethyl. For upland crop area, 216 weed species belonged to 46 families were recorded. One hundred and sixtyfive of these were grown in winter crop area while 189 weed species occurred in summer crop area, respectively. Among these, 138 weed species were grown in both crop seasons. In general, summer crops had less number of weed species compared to winter crops. Even though the dominant weed species varied by crop the most common weeds were Chenopodium album, Alopecunrs aqualis, Stellaria alsine and S, media for winter crops and Digitaria sanguinalis, Portulaca oleracea, Chenopodium album and Acalypha australis for summer crops, respectively.

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Comparison of the measurement methods of soil water content by error analysis (토양수분(土壤水分) 함량(含量) 측정방법별(測定方法別) 오차분석(誤差分析)에 의(依)한 비교(比較))

  • Eom, K.C.;Ryu, K.S.;Um, K.T.
    • Korean Journal of Soil Science and Fertilizer
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    • v.21 no.4
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    • pp.367-372
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    • 1988
  • A series of field experiment was conducted to find out error range and to compare precision based on error analysis of soil water content measured with gravimetric, surface & depth neutron and gypsum block methods in a sandy loam soil. The error of soil water content measured with gravimetric (core-sampling), surface and depth neutron method showed quardratic curve, whereas that with gypsum block was exponential curve in relation to soil water content. Within the range of volumetric soil water content from 11 to 33%, the error of soil water content measured with gravimetric, surface neutron, depth neutron and gypsum block method was ranged from 0.28 to 3.49%, 0.71 to 2.63%, 0.52% to 1.01% and 0.05 to 21.89%, respectively. The error of soil water content measured with depth neutron method was lower than those of other methods, when the soil water content was more than 14% in sandy loam soil. The relative number of replicates of soil water measurement for surface neutron, depth neutron and gypsum block method to attain same precision for gravimetric method was 0.6-1.7, 0.07-0.8 and 0.1-125, respectively.

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The Effect of Some Amendments to Reduce Ammonia during Pig Manure Composting (몇 가지 처리제의 첨가에 의한 돈분의 퇴비화 과정 중 암모니아 발생 저감 효과)

  • Joo, Jin-Ho;Kim, Dae-Hoon;Yoo, Jae-Hong;Ok, Yong-Sik
    • Korean Journal of Soil Science and Fertilizer
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    • v.40 no.4
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    • pp.269-273
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    • 2007
  • Occurrence of malodor could cause adverse impacts on human health and increase public interest. Therefore, scientific methods to decrease odor is required. Endeavor to decrease odor from compost however has not fully been successful. The purpose of this research is assessment of some amendments to reduce $NH_3$ from immature composts. Calcium hydroxide was applied to composts due to it's characteristics to increase pH. Activated carbon and zerovalent iron (ZVI) were selected because of their adsorption properties. The research results were as follows: Calcium hydroxide, activated carbon, zerovalent iron increased the composting temperature above $60^{\circ}C$. The addition of calcium hydroxide, activated carbon, and ZVI to compastry process increased pH 8.6 - 8.8 from $1^{st}$ day to $14^{th}$ day. During the 14 days of composting, addition of calcium hydroxide, activated carbon and ZVI changed EC from $2.15-0.66dS\;m^{-1}$, $1.48-1.11dS\;m^{-1}$, respectively and $1.77-0.68dS\;m^{-1}$. The difference in EC of the compost was due to irregularities of samples. Organic matter in the compost decreased through out theexcept control. The $NH_4-N/NO_3-N$ ratio of all experimental compost increased through the process. The addition of activated carbon, calcium hydroxide and ZVI decreased $NH_3$ from 0.1ppm, 0.7ppm and 1.7ppm more than the control (pig manure and sawdust), 9.3ppm, in 30 days of composting. In conclusion, odor from prematured compost decreased by addition of chemicals like calcium hydroxide, activated carbon, zerovalent iron. Moreover, use of these $NH_3$ reducers alone or together combined at different periods of composting etc. could decrease $NH_3$.

Eligibility Standards for Recognized Organization Personnel Responsible for Statutory Survey (정부대행검사기관 선박검사원의 자격기준에 관한 연구)

  • Lee, Sang-Il;Jung, Min;Jeon, Hae-Dong
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.26 no.4
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    • pp.366-373
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    • 2020
  • According to Article 77 of the Ship Safety Act and Article 97(2) of the Enforcement Ordinance of the Ministry, the Recognized Organization (RO) personnel (ship surveyors) responsible for statutory survey shall have educational qualifications and experience in a specific field or obtain a license under the National Technical Qualifications Act. However, graduates from maritime high schools and those who completed the short-term course of the Ocean Polytec did not satisfy the qualification standards for the RO personnel since they did not graduate from the departments of maritime/fisheries or shipbuilding. Major shipping countries such as the United Kingdom, the United States, and Canada use the IACS (International Association of Classification Societies) regulations, and the Ship Safety Act in Japan has eliminated the qualification requirements for ship surveyors. In particular, under the IMO (International Maritime Organization) and IACS regulations, the RO personnel shall have as a minimum the following formal educational background: a degree or equivalent qualification from a tertiary institution recognized within a relevant field of engineering or physical science (minimum two years' program); or a relevant qualification from a marine or nautical institution and relevant sea-going experience as a certified ship officer; and competency in the English language commensurate with their future work. Considering that Article 17 of the Enforcement Decree on Public Officials Appointment Examinations prohibits educational restrictions and there are no educational restrictions on the qualifications of British and Japanese surveyors, if the maritime high school graduates have sufficient sea-going experience, education, and training, they could be recognized as meeting the qualification requirements. Moreover, those who completed the short-term course of the Ocean Polytec could also be recognized as meeting the qualification requirements because they are required to have at least a professional bachelor's degree (in the case of a third-class CoC (Certificate of Competancy)) and some sea-going experience after completion.