• Food Science of Animal Resources
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• v.29 no.6
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• pp.709-718
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• 2009

The purpose of this study was to search for physical treatments to reduce allergenicity of pork. Physical treatments such as heating, autoclave, microwave, sonication, and irradiation have been used for food processing or reduction of allergenicity. The porcine serum albumin (PSA), known as a major allergen in pork, was extracted after physical treatments. The antigenicity of pork extracts by heating (80 and $100^{\circ}C$ for 20 min), autoclave ($121^{\circ}C$ for 5, 10, and 30 min), and microwave (for 5 and 10 min) was significantly decreased. Especially, the binding ability of p-IgG to pork extracts by autoclave for 30 min showed the greatest decrease (about 3%) in physical treatments. However, the antigenicity of pork was unaffected by sonication and irradiation treatment. These results indicated that the autoclave treatment was the most effective method to reduce the antigenicity of pork.

• Journal of the Korean Society of Food Science and Nutrition
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• v.35 no.9
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• pp.1127-1132
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• 2006

In our previous study, a novel herb mixture (HIM-I) of Angelica gigas radix, Cnidium officinale rhizoma, and Paeonia japonica radix was developed to protect the intestinal and immune systems and promote its recovery against radiation damage. A new herbal composition (HemoHIM) with the high immune modulating activity was developed from HIM-I. HIM-I was fractionated into ethanol fraction (HIM-I-E) and polysaccharide fraction (HIM-I-P). And HemoHIM was prepared by adding HIM-I-P to HIM-I. HemoHIM showed more effective than HIM-I in immune modulation as well as radioprotection. The present study is designed to investigate the protective effects of HIM-I, HIM-I-P, and HemoHIM on hydrogen peroxide $(H_2O_2)$ induced apoptosis of human promyelocytic leukemia (HL-60) cells. It was shown that $H_2O_2$ treatment reduced the viability of cells, and increased appearance of DNA ladders, hypodiploid (subG1) cells, and phosphatidylserine translocation level. Pretreatment of HemoHIM significantly reduced the cytotoxic effect induced by $H_2O_2$, associated with reducing the translocation of phosphatidylserine, hypodiploid cells and DNA ladders. HemoHIM appeared to be more protective than HIM-I against $H_2O_2$ induced apoptosis whereas, it exhibited similar activity to HIM-I-P. These results indicated that HemoHIM might be an useful agent for protection against oxidative stress $(H_2O_2)-induced$ apoptosis as well as immune modulation, especially since it is a relatively nontoxic natural product.

• Economic and Environmental Geology
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• v.54 no.5
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• pp.535-547
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• 2021

Aggregate is an essential construction material, and the demand is increasing every year. Aggregate has different properties in each region, and it is difficult to supply it over long distances due to its quantity and weight. For the stabilization of aggregate supply and demand, regional aggregate resource surveys have been conducted since 1993 in Korea. In this study, an aggregate resource survey was conducted in Goyang City to understand the characteristics of aggregate distribution as part of the annual regional aggregate resource survey in 2020. Goyang City has a high mountainous area to the east, and the southwestern part shows a topography where a wide flatland develops. It has 18 small streams originated from the eastern mountainuos area and 1 large stream Han River. The drilling data shows that thickness of the Quaternary deposits tend to deepen toward the south. The aggregate reserves are relatively abundant, the depth of the aggregates are relatively deep. Changes in the depth of the Quaternary deposits and the amount of aggregate in Goyang are seems to be closely related to the activities of the Han River rather than the sedimentation characteristics from the upstream to the downstream of the small streams. This characteristics show a similar tendency to the distribution of aggregates in adjacent regions to the west coast in Korea. Therefore, the regions that close to west coast have a high probability of aggregate reserves around relatively large-scale streams flowing into the west coast.