• Maxillofacial Plastic and Reconstructive Surgery
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• 제36권3호
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• pp.111-115
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• 2014

Purpose: This study evaluated powdered burn wound dressing materials from wild silkworm fibroin in an animal model. Methods: Fifteen rats were used in this experiment. Full-thickness $2{\times}2cm$ burn wounds were created on the back of rats under anesthesia. In the two experimental groups, the wounds were treated with two different dressing materials made from silkworm fibroin. In the Control Group, natural healing without any dressing material was set as control. The wound surface area was measured at five days, seven days and 14 days. Wound healing was evaluated by histologic analysis. Results: By gross observation, there were no infections or severe inflammations through 14 days post-injury. The differences among groups were statistically significant at seven days and 14 days, postoperatively (P<0.037 and 0.001, respectively). By post hoc test, the defect size was significantly smaller in experimental Group 1 compared with the Control Group and experimental Group 2 at seven days postoperatively (P=0.022 and 0.029, respectively). The difference between Group 1 and Group 2 was statistically significant at 14 days postoperatively (P<0.001). Group 1 and control also differed significantly (P=0.002). Group 1 showed a smaller residual scar than the Control Group and Group 2 at 14 days post-injury. Histologic analysis showed more re-epithelization in Groups 1 and 2 than in the Control Groups. Conclusion: Burn wound healing was accelerated with silk fibroin spun by wild silkworm Antheraea pernyi. There was no atypical inflammation with silk dressing materials. In conclusion, silk dressing materials can be used for treatment of burn wound.

• Journal of Pharmaceutical Investigation
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• 제36권5호
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• pp.339-342
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• 2006

This study was designed to prepare an animal model for partial thickness bum wound which can be employed for testing topical therapy. We first evaluated whether rabbit ear and mouse back skin wound model could differentiate the wound healing process in terms of degree of re epithelialization, required days for complete wound closure, presence of scarring. $2^{nd}$ degree wet bum were prepared on mouse back skin and rabbit ear by applying 5 mL hot water($85{\pm}0.1^{\circ}C$) for 7 see followed by 5 mL ice-cold 0.5% acrynol solution for cooling and disinfecting the inflicted area. After removing the dead epidermis layer at 24 hr, tested dressings were applied for specified time and wound progression was investigated. In mouse model, wound contraction was the primary wound closing mechanism, which is quite different from human wound healing process. In rabbit ear model, epidermal regeneration was the major wound healing process rather than wound contraction and the difference in wound healing property among tested dressings could be clearly demonstrated. A rabbit ear model could differentiate the wound progression among open, occluded and epidermal growth factor(EGF) treated wound. Four sites of circular wound(diameter: 1 cm) on the anterior part of rabbit ear could be employed for the comparative wound healing study. For obtaining reproducible bum wound, degree of bum depth and bum sites should be carefully controlled in addition, employing rabbits of same strain and weight. The result suggests that rabbit ear could be employed as a reliable and human-resembled wound model.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 1999년도 추계학술발표회요약집
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• pp.246-246
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• 1999

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1997년도 춘계학술대회 논문집
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• pp.8-13
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• 1997

In order to utilize the information of well-known grinding data or grinding machine, a database needs to be designed by considering the delicate property of the machine tools for the high precision and quality of the demanding specification. Among the machine tools, machining conditions of the grinding are various and knowledge repeatance obtained form the grinding process are less credable.Therefore it is desirable for D/B, which is used to set the grinding conditions, to utilize the maximum machine tool capability. The present paper studied occurance limit of chatter vibration and burn considering the characteristics of machine tool. And also basic experiments were performed to establish optimum grinding canditions which can maximize the machining efficiency.

• 한국방재학회:학술대회논문집
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• 한국방재학회 2010년도 정기 학술발표대회
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• pp.60.2-60.2
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• 2010

본 연구에서는 분포형 강우-유출 모델을 이용한 홍수량 산정방법을 국내 유역에 도입하여 그 적용성을 검토하였다. 대상지역은 강우-유출 자료가 체계적으로 관리되고 있는 평창강 유역으로 선정하였으며, 하천도와 흐름경로도는 수치지도상의 하천성을 이용하여 수치고도모델에서 하도의 번인(Burn-In)기능을 사용하여 생성하였다. 1983년부터 2006년까지 관측된 호우사상중 1,000이상의 첨두홍수량을 발생시킨 6개의 주요 호우사상들에 대해 모의하였으며, 모형의 결과는 실측치와 비교하여 잘 일치하였다. 분포형 모형을 적용하게 되면 매우 작은 지방2급 하천까지의 계획의 수립이 가능하기에 본 모형을 통한 홍수량 산정의 품질이 크게 업그레이드 될 것이라 판단된다.

• Nuclear Engineering and Technology
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• 제54권8호
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• pp.3130-3139
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• 2022

Direct containment heating (DCH) is one of the potential factors leading to early containment failure. DCH is closely related to safety analysis and containment performance evaluation of nuclear power plants. In this study, a DCH prediction program was developed to analyze the DCH loads of containment vessel. The phenomenological model of debris dispersal, metal oxidation reaction, debris-atmospheric heat transfer and hydrogen jet burn was established. Code assessment was performed by comparing with several separate effect tests and integral effect tests. The comparison between the predicted results and experimental data shows that the program can predict the key parameters such as peak pressure, temperature, and hydrogen production in containment well, and for most comparisons the relative errors can be maintained within 20%. Among them, the prediction uncertainty of hydrogen production is slightly larger. The analysis shows that the main sources of the error are the difference of time scale and the oxidation of cavity debris.

• 한국병원경영학회지
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• 제17권4호
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• pp.167-187
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• 2012

Organizational growth is achieved through the process of finding opportunities in the environment and establishing a business model with internal and external resources. Bestian Hospital, which primarily focuses on saving the lives of patients with severe burns, has enlarged its business domain through deep understanding of burn patients' problems, including pain and complications during treatments, long-term treatments, skin reconstruction, and so on. Now Bestian is accelerating research for development of antipyretics and cosmetics for burn patients. The success of Bestian has been due to utilization of human and material resources that are essential to performance in the medical field. Also, Bestian properly used a management service organization(MSO) model and constructed an information technology(IT) system for supporting its businesses. However, previous successes do not guarantee continued success. Bestian is entering a new domain with different challenges than it has experienced so far, and how it deals with these challenges will decide its future.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1985년도 하계학술회의논문집
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• pp.55-60
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• 1985

A state-space model of a burn through point control system of an industrial sintering process is derived. The model is then used in designing a self-tuning controller which consists of the receding horizon control law and a least-squares prediction algorithm. By applying this adaptive controller to POSCO sintering process IV, satisfactory expermental results have been obtained. Some of these practical results are presented in this paper.

• Journal of Plant Biotechnology
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• 제37권4호
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• pp.549-555
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• 2010

본 연구는 칼슘 수송체의 하나인 sCAX1과 칼슘결합단백질의 하나인 CRT가 토마토에서 발현했을 때 tip-burn과 배꼽썩음병 (BER)이 토마토의 전 생육기간에 걸쳐 어떠한 양상으로 나타나는지를 관찰하는 것에 초점을 맞추어 수행하였고, 최종 연구 결과는 CRT 공동발현이 sCAX1 발현에 의해 야기된 병징을 억제시킬 수 있음을 확인시켰다. 양분공급이 불량한 환경하에 놓인 sCAX1 단독 발현 토마토 식물체는 그 근단 조직, 정단 조직 및 과실의 암술부착부위 조직에 토마토 재배 농가포장에서 빈번하게 관찰되는 칼슘결핍 증상과 일치하는 괴사현상을 나타내었다. sCAX1 형질전환체와 비형질전화체를 각각 대목과 접수로 달리 사용한 교호접목 실험을 통해 sCAX1 발현에 따른 tip-burn 병징이 토양으로부터의 칼슘이온 흡수에 장애를 받아 생긴 결과가 아님을 확인하였다. 형질전환을 통해 CRT 발현 토마토를 획득한 후 CRT가 sCAX1에 의한 불량한 특성 발현을 제어할 수 있는지 확인하기 위하여 양자간 교배조합을 작성하였다. sCAX1과 CRT를 토마토에서 공동발현 시켰을 때 완벽하지는 않지만 양극 조직의 괴사와 BER이 뚜렷하게 감소되었다. 본 연구의 결과를 바탕으로 sCAX1 발현에 의해 방해 받은 세포 내 칼슘 이온 관련 어떤 기구는 CRT 공동발현을 통해 복구될 수 있다는 하나의 모델을 제시할 수 있을 것이다.

• 대한토목학회논문집
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• 제26권1D호
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• pp.177-184
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• 2006

본 연구는 평택시($12.2km^2$)를 대상으로 시내의 각 도로를 따라 흐르는 홍수유출을 모의하기 위하여 분포형 도시홍수 유출 모형을 개발하고, 그 적용가능성을 제시하고자 하였다. 도로를 따라 유출이 모의되는 것을 처리하기 위하여 도로망을 이용하여 Agree burn한 수치표고모델의 준비를 제안하였으며, 본 연구에서는 모형의 입력자료로 적합한 도로해상도를 15m로 결정하였다. 모형의 적용가능성을 평가하기 위하여 32개의 도로지점을 선정하여 각 도로지점별 유출곡선을 모의한 결과, 고지대에서 저지대로의 도로유출이 합리적으로 모의되었으며, 도로에서의 빗물배제량을 고려한 도로지점별 모의결과도 합리적으로 모의됨을 확인할 수 있었다.