• Title/Summary/Keyword: Brachytherapy

Search Result 223, Processing Time 0.11 seconds

The Clinical Application of Radioactive Iridium (Ir-192) Brachytherapy (방사선 이리디움(Ir-192) 근접치료의 임상적 응용)

  • Yoo, Seong-Yul
    • The Journal of Korean Society for Radiation Therapy
    • /
    • v.3 no.1
    • /
    • pp.11-18
    • /
    • 1989
  • Brachytherapy is known to be a good modality to achieve local control as a boost treatment following limited external irradiation, which may reduce the external beam related complication particularly in head and neck cancer. The authors developed iridium-192 ribbons recently to replace the radium needles in the field of brachytherapy. Total of 48 cases of head and neck and pelvic-perineal cancer patients had been treated with Ir-192 ribbons during last two years from October 1986 to September 1988, and the results were analyzed to assess the applicability of the fabricated sources. The conclusion is as follows; 1. Iridium implant resulted excellent tumor control effect in clinical application. 2. Iridium is superior than radium and cecium in brachytherapy because of easier to use and lesser exposure to the personnel. 3. Afterloading technique is useful to modify dose distribution, to expand treatment site and method, and to develop interstitial hyperthermia.

  • PDF

Ir-192 Brachytherapy Planning of Brain Tumor (Ir-192 방사성소선원에 의한 뇌종양의 치료계획)

  • Choi Tae Jin;Park Jeong Ho;Kim Ok Bae;Suh Soo Ji
    • Radiation Oncology Journal
    • /
    • v.6 no.2
    • /
    • pp.277-281
    • /
    • 1988
  • Although widely used in external beam treatment planning, computed tomography scans are infrequent in incranial tumors by implanting of Radioactive isotope. This incranial brachytherapy has only become possible by using CT scans and stereotaxic operation methods. The coincidence of single source and tumor axes in brachytherapy is very important to determine the therapeutic dosages. Eventhough using the CT scan, according to spatial location of tumor tying, the section of tumor will be seen enlargement, cause the tumor will be cut off with slight angle to its axes. Correct analysis of tumor size from source is required for rotated axes in analytical geometry.

  • PDF

Dosimetry of Brachytherapy Sources: Review of The AAPM TG-43 Formalism

  • Cho, Sang-Hyun
    • Proceedings of the Korean Society of Medical Physics Conference
    • /
    • /
    • pp.141-143
    • /
    • 2002
  • In 1995, the American Association of Physicists in Medicine (AAPM) Task Group 43 published a report dealing with the dosimetry of interstitial brachytherapy sources, generally known as the TG-43 report. Compared to previously adopted formalisms, a formalism proposed in this report provides a more accurate and systematic brachytherapy dose calculation method, especially for Ir-192 and other low energy gamma sources such as 1-125 and Pd-l03. In this lecture, an overview of the TG-43 formalism will be presented, along with the lecturer's experience in determining the TG-43 parameters by the Monte Carlo method and experimental methods such as TLD and radiochromic film.

  • PDF

Design of a New Applicator for High-Dose Rate Vaginal Brachytherapy (고선량율 질강 근접조사를 위한 새로운 적용구의 제작)

  • Shin, Sei One
    • Yeungnam University Journal of Medicine
    • /
    • v.17 no.2
    • /
    • pp.123-128
    • /
    • 2000
  • Purpose: This study was aimed to develop a new vaginal applicator(Shin's Applicator) for 2-channel high-dose rate vaginal brachytherapy to evaluate uniformity of surface dose, and to present 3-dimensional dose distribution of the applicator. Methods: Shin's Applicator was inexpensively constructed using human soft tissue equivalent acrylic bar. We evaluated dose uniformity along the applicator surface using film densitometer and performed vaginal intracavitary brachytherapy after insertion of the applicator using HDR brachytherapy planning software and brachytherapy unit(Ralstron-20B). Results: Shin's Applicator allows improved dose distribution than the existing 1-channel cylinder and achieves diminished urinary bladder and rectal dose by 20%. Conclusions: From the above results, it can be concluded that Shin's Applicator may be an improved form of a vaginal applicator. Furthermore, it can be suggested that this applicator has an advantage, for it prevents vaginal stenosis after radiation therapy and can be used as a disposable vaginal dilator. Further follow up examination with radiological study may be helpful to evaluate the therapeutic efficacy of this applicator.

  • PDF

A comparison of preplan MRI and preplan CT-based prostate volume with intraoperative ultrasound-based prostate volume in real-time permanent brachytherapy

  • Park, Hye-Li;Kim, Ja-Young;Lee, Bo-Mi;Chang, Sei-Kyung;Ko, Seung-Young;Kim, Sung-Jun;Park, Dong-Soo;Shin, Hyun-Soo
    • Radiation Oncology Journal
    • /
    • v.29 no.3
    • /
    • pp.199-205
    • /
    • 2011
  • Purpose: The present study compared the difference between intraoperative transrectal ultrasound (iTRUS)-based prostate volume and preplan computed tomography (CT), preplan magnetic resonance imaging (MRI)-based prostate volume to estimate the number of seeds needed for appropriate dose coverage in permanent brachytherapy for prostate cancer. Materials and Methods: Between March 2007 and March 2011, among 112 patients who underwent permanent brachytherapy with $^{125}I$, 60 image scans of 56 patients who underwent preplan CT (pCT) or preplan MRI (pMRI) within 2 months before brachytherapy were retrospectively reviewed. Twenty-four cases among 30 cases with pCT and 26 cases among 30 cases with pMRI received neoadjuvant hormone therapy (NHT). In 34 cases, NHT started after acquisition of preplan image. The median duration of NHT after preplan image acquisition was 17 and 21 days for cases with pCT and pMRI, respectively. The prostate volume calculated by different modalities was compared. And retrospective planning with iTRUS image was performed to estimate the number of $^{125}I$ seed required to obtain recommended dose distribution according to prostate volume. Results: The mean difference in prostate volume was 9.05 mL between the pCT and iTRUS and 6.84 mL between the pMRI and iTRUS. The prostate volume was roughly overestimated by 1.36 times with pCT and by 1.33 times with pMRI. For 34 cases which received NHT after image acquisition, the prostate volume was roughly overestimated by 1.45 times with pCT and by 1.37 times with pMRI. A statistically significant difference was found between preplan image-based volume and iTRUS-based volume (p<0.001). The median number of wasted seeds is approximately 13, when the pCT or pMRI volume was accepted without modification to assess the required number of seeds for brachytherapy. Conclusion: pCT-based volume and pMRI-based volume tended to overestimate prostate volume in comparison to iTRUS-based volume. To reduce wasted seeds and cost of the brachytherapy, we should take the volume discrepancy into account when we estimate the number of $^{125}I$ seeds for permanent brachytherapy.

Evaluation of Absorbed Dose According to Nanoparticle Density During the Breast Cancer Brachytherapy (유방암 근접치료 시 나노입자의 밀도에 따른 흡수선량 평가)

  • Lee, Deuk-Hee;Nam, Ji-Hee;Kim, Jung-Hoon
    • Journal of radiological science and technology
    • /
    • v.42 no.2
    • /
    • pp.131-135
    • /
    • 2019
  • The purpose of this study was to evaluate the efficacy of brachytherapy of breast cancer by dose assessment which a steady increased in Korea women. The dose assessment was performed using the MCNPX program, a MonteCarlo simulation technique. The sources used for brachytherapy was 192Ir. And nanoparticle which used for dose enhancement was gold. The density of nanoparticle was 7, 18 and 30 mg. Evaluation of absorbed dose according to distance is measured at a distance of 30, 50, 100 and 200 cm from the patient. As a result, The breast absorbed dose results increased in proportion to the density of nanoparticle. And the surrounding organs were not significantly different according to the density. But, in some organs, the absorbed dose decreased as the density of nanoparticles increased. Absorbed dose according to the distance was in inverse proportion to distance.

Radiation Dose Calculation using MIRD TYPE PHANTOM in the Surrounding Organs during Brachytherapy of Breast Cancer (유방암의 근접치료 시 수학적 모의피폭체를 이용한 인접장기의 선량평가)

  • Park, Eun-tae;Kim, Jung-hoon;Im, In-chul
    • Journal of the Korean Society of Radiology
    • /
    • v.10 no.4
    • /
    • pp.271-278
    • /
    • 2016
  • This study was fulfilled to evaluate the absorbed dose of breast and adjacent organs using MIRD type phantom in brachytherapy of breast cancer. The absorbed dose was analyzed assuming left or right breast is source organ which is $^{103}Pd$ or $^{192}Ir$. As a result, $^{192}Ir$ dose is higher than $^{103}Pd$ in source organ and also in contralateral breast. Particularly, significant adjacent organs are lung, liver, heart and contralateral breast in brachytherapy of breast cancer.

Remote After Loading HDR Brachytherapy for Female Urethral Cancer (여성 요도암의 원격조정 고선량 근접치료)

  • Cho Jeong Gil;Choi Eun Kyung;Chang Hyesook;Yi Byong Yong;Kim Kwang Hoon;Lee Jong Goo
    • Radiation Oncology Journal
    • /
    • v.9 no.2
    • /
    • pp.319-324
    • /
    • 1991
  • In our institution, a 76-year-old woman with primary urethral carcinoma was treated with remote afterloading high dose rate (HDR) interstitial brachytherapy using micro selectron Ir-192. In this paper, authors described the technical aspect of remote afterloading HDR interstitial brachytherapy for female urethal cancer.

  • PDF