• Journal of Radiation Protection and Research
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• v.32 no.1
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• pp.35-44
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• 2007

Sealed sources have to conducted the tests be done according to the classification requirements for their typical usages in accordance with the relevant domestic notice standard and ISO 2919. After each test, the source shall be examined visually for loss of integrity and pass an appropriate leakage test. Tests to class a sealed source are temperature, external pressure, impact, vibration and puncture test. The environmental test conditions for tests with class numbers are arranged in increasing order of severity. In this study, the apparatus of tests, except the vibration test, were developed and applied to three kinds of sealed source. The conditions of the tests to class a sealed source were stated and the difference between the domestic notice standard and ISO 2919 were considered. And apparatus of the tests were made. Using developed apparatus we conducted the tests for $^{192}Ir$ brachytherapy sealed source and two kinds of sealed source for industrial radiography. $^{192}Ir$ brachytherapy sealed source is classified by temperature class 5, external pressure class 3, impact class 2 and vibration and puncture class 1. Two kinds of sealed source for industrial radiography are classified by temperature class 4, external pressure class 2, impact and puncture class 5 and vibration class 1. After the tests, Liquid nitrogen bubble test and vacuum bubble test were done to evaluate the safety of the sealed sources.

• The Korean Journal of Nuclear Medicine
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• v.33 no.2
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• pp.163-171
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• 1999

Purpose: Liquid beta emitter filled in angioplasty balloon could be used to perform endovascular balloon brachytherapy to prevent coronary artery restenosis. We investigated the dosimetry for Re-188-DTPA liquid-filled balloon and medical internal radiation dosimetry in case of balloon leakage. Materials and Methods: We estimated radiation dose from an angioplasty balloon (20 mm length, 3 mm diameter cylinder) to the adjacent vessel wall using Monte Carlo EGS4 code. We obtained time-activity curves of kidneys in normal dog and calculated $T_{max},\;T_{1/2}$. Using MIRDOSE3 program, we estimated absorbed doses to the major organs (kidneys, bladder) and the whole body when we assumed that balloon leaked all the isotope contained. Results: The radiation dose was 17.5 Gy at the balloon surface when we applied 3,700 MBq/ml of Re-188 for 100 seconds, Fifty percent of the energy deposited within 1 mm from the balloon surface. The estimated internal dose to the whole body was 0.005 mGy/MBq and 18.5 mGy for the spillage of 3,700 MBq of Re-188. Conclusion: We suggest that Re-188-DTPA can be used for endovascular balloon brachytherapy to inhibit coronary artery restenosis after angioplasty with tolerable whole body radiation dose in case of balloon rupture.

• Progress in Medical Physics
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• v.21 no.2
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• pp.223-231
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• 2010

We have taken surveys about total 72 departments of radiation oncology which is performing the treatment with linear accelerator and brachytherapy unit in Korea. The survey was included the research about the linear accelerator, brachytherapy, Also, we surveyed the various performance (QA period, manpower, time) of quality control for understanding of efficiency. The survey results show that the QA test of daily and weekly are almost same comparing to USA and Europe but the QA performance of monthly and yearly in Korea are 15.5 which is less than USA and Europe recommended QA item number of 17 to 21. The manpower and QA time in Korea also lower than 50% of USA and Europe recommended because the manpower and QA time limitation in Korea. It will be expected that the manual of quality management in each clinic could be appropriately established when combining the present results with previously published AAPM TG-40 and other protocols.

• Radiation Oncology Journal
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• v.36 no.2
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• pp.147-152
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• 2018

Purpose: To evaluate the treatment outcomes of adjuvant external beam radiation therapy (EBRT) and vaginal brachytherapy (VB) following radical hysterectomy in cervical cancer patients with involved vaginal resection margin (VRM). Materials and Methods: We retrospectively reviewed the medical records of 21 patients treated with postoperative EBRT and VB for positive VRM FIGO stage IB-IIA cervical cancer between 2003 and 2015. Concurrent platinum-based chemotherapy was administered to all patients. Results: The median whole pelvis EBRT dose was 50.4 Gy (range, 45 to 50.4 Gy). In the VB, the median dose per fraction, number of fractions, and total dose delivered were: 4 Gy (range, 3.0 to 4.0 Gy), 4 fractions (range, 3 to 5 fractions), and 16 Gy (range, 12 to 20 Gy), respectively. At a median follow-up of 46 months (range, 9 to 122 months), local recurrence was observed in 2 patients, and distant metastasis was present in 7 patients. All patients with local recurrence subsequently developed distant metastases. The 5-year local control, disease-free survival, and overall survival rates were 89.1%, 65.9%, and 62.9%, respectively. Of the 21 patients, 7 patients (33.3%) reported grade 2 acute toxicity; however, there were no grade 3 or higher acute adverse events. Grade 1-2 late toxicities were observed in 8 patients. Late grade 3 urinary toxicity was reported in 1 patient. Conclusions: Adjuvant EBRT and VB showed excellent local control and low toxicity in cervical cancer patients with positive VRM. Although limited by its retrospective nature, the findings from our study provide evidence supporting the use of additional VB in pathologically involved VRM.

• Progress in Medical Physics
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• v.15 no.4
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• pp.192-196
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• 2004

The activity of Ir-192 sources for high dose rate (HDR) Brachytherapy in Korea were measured by using the well-type chamber and using the calibration Jig with the Farmer-type ionization chamber to compare the manufacturer certificated source strength which is supplied with each new Ir-192 source. The activity of two different source models used in six hospitals were measured. The range of measured activities to the manufacturer's suggested ones was -2.40% to +3.31% for the calibration Jig and -3.12% to 0.00% for the well-type chamber system. The source strength values given by the manufacturer for the 6 sources were within ${\pm}5%$ for the two different measuring equipment. Our results demonstrate that well-type chamber as wall as Farmer-type chamber system are appropriate system for the routine source calibration procedures in HDR brachytherapy. Whenever a new source is installed to use in clinics, a source calibration should be carried out.

• Progress in Medical Physics
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• v.25 no.4
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• pp.248-254
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• 2014

The purpose of this study is to develope a control system for a small X-ray tube generator and investigate control methods for the X-ray generator. The small X-ray tube was developed for electronic brachytherapy, and thus, the new control method should be investigated, if the small X-ray tube is used for the imaging system. The Axxent S700 X-ray tube and the XF060NZZ485 high voltage generator were used to compose a X-ray imaging system and control board was developed by using AT90CAN128 MCU. The two control methods were investigated after tube voltage was set to 50 kV, one was filament current control method and the other was beam current control method. The former was subdivided into two methods according to the filament heating time, the 5 and the 10 seconds respectively. In the filament current method, the beam current did not rise up to the desired value, if the filament current had not been maintained for at least 10 seconds. The onset filament currents to generate beam current were varied from 1,300 to 1,350 mA and over 5 seconds were needed in order to reach the desired tube current value after beam current was generated. However, in the tube current control method, the beam current reached to the desired value without any time delay with the filament current of 1,500 mA. In this study, we found that the beam current control method was appropriate for the use of small X-ray tube developed for brachytherapy in the X-ray imaging system.

• Journal of the Korean Society of Radiology
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• v.16 no.6
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• pp.735-740
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• 2022

In order to reduce side effects such as rectal bleeding in the Brachytherapy, the rectal retractor and wet gauze have been used to increase the distance between the rectum and the tandem. However, there were disadvantages that it was difficult to insert through a narrow entrance into the vagina and poor reproducibility. Also, based on the CT image of the selected catheter, the distance from the tandem to the rectum with or without the balloon catheter was checked and the reduction of the dose to the rectum was confirmed. As a result of the experiment, catheter No. 7 was selected considering the maximum balloon size at a level that does not affect the distance between the start point of the balloon and the end of the catheter, and the ovoid applicator. Based on the CT image of the selected catheter, the degree of expansion according to the presence or absence of the balloon catheter was compared, and it was found that the distance difference was 0.3 - 1 cm. In addition, it was confirmed that a decrease of about 32% was observed due to this distance difference. Therefore, the actual clinical application of the selected catheter can be used as a substitute for the existing rectal retractor and wet gauze.

• Progress in Medical Physics
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• v.1 no.1
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• pp.85-90
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• 1990

Berger formulation was used to calculate the dose distribution of $^{60}$ Co source in tissue. $^{60}$ Co source was supposed as point source. The effect of the stainless-steel around the source was considered and Taylor Approximation Method was used for calculating exposure build-up factor. Calculated depth dose data was compared with measured data which was measured by the ionization chamber.

• Progress in Medical Physics
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• v.4 no.1
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• pp.17-21
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• 1993

근접방사선치료는 방사성동위원소를 종양에 밀착시키거나 또는 종양내에 직접 삽입하여 치료하는 방법으로서 종양에는 일시에 많은 선량을 주는 반면 주위 정상조직에는 선량을 최소화시킬 수 있는 장점이 있다. 따라서 근래에 들어 종양치료에 있어서 외부방사선치료와 병행하여 근접방사선치료를 시행하는 병원이 증가하고 있다. 그러나 근접방사선치료는 방출 방사선의 에너지가 낮고, 대부분 짧은 반감기를 가지며, 소형의, 수 mCi에서 수Ci 정도의 방사능을 가진 방사성동위원소들을 인체에 직접 삽입하는 것으로 정확한 선량 분포를 위해서는 방사성동위원소의 방사능량, 위치, 분포 등의 정확성 확보가 절실히 요구된다. 따라서 이 논문은 근접방사선치료시스템의 QA프로그램 개발을 위하여 작성하였다.

• Proceedings of the Korean Nuclear Society Conference
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• 2005.10a
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• pp.759-760
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• 2005