• Title, Summary, Keyword: Botanical drug

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The worldwide trend of using botanical drugs and strategies for developing global drugs

  • Ahn, Kyungseop
    • BMB Reports
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    • v.50 no.3
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    • pp.111-116
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    • 2017
  • Natural product drugs, or botanical drugs, are drugs composed of natural substances which have constituents with healthenhancing or medicinal activities. In Korea, government-led projects brought attention to botanical drugs invigorating domestic botanical drug industry. Foreign markets, as well, are growing bigger as the significance of botanical drugs stood out. To follow along with the tendency, Korea puts a lot of effort on developing botanical drugs suitable for global market. However, standards for approving drug sales vary by countries. And also, thorough standardization, certification, clinical studies and data of these will be required as well as data confirming safety and effectiveness. Meanwhile, as an international exchange in botanical drug market continues, the importance of plant resources was emphasized. Thus countries' ownership of domestic natural resources became vital. Not only establishing a systematic method to secure domestic plant resources, but also cooperation with other countries on sharing natural resources is essential to procure natural resources effectively. Korea started to show visible results with botanical drugs, and asthma/COPD treatment made out of speedwell is one example. Sufficient investment and government's active support for basic infrastructure for global botanical drugs will bring Korea to much higher level of botanical drug development.

Pharmacognostical Studies on the "Se Sin" (세신의 생약학적 연구)

  • 박정희
    • Korean Journal of Plant Resources
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    • v.9 no.2
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    • pp.183-188
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    • 1996
  • Chinese crude drug 'Se Sin'(細辛)has been used to cure headache, cough and expectorant. To the botanical origin of 'Se Sin', Zhong-yao-zhi(中葯志) reported Asarum heterotropoides var. mandshuricum. A. sieboldii and A. sieboldii var. seoulensis, and Zhong-yao-da-ci-dian(中葯大辭典) reported Asarum heterotropoides var. mandshuricum and A. sieboldii of Aristolochiaceae. In Korea, this crude drug has been used as a Korean folk remedy for tothache and aromatic. The botanical origin of 'Se Sin' is considered to be Asarum species of Aristolochoaceae. But there has no pharmacognostical confirmation on it. To clarify the botanical origin of 'Se Sin', we studied on the anatomical characteristics of Asarum species growing wildly in Korea i.e. A. maculatum, A. sieboldii, A. sieboldii var. seoulensis, and of 'Se Sin' from Korea on Korean market. Through our studies, the botanical origin of 'Se Sin' from Korea was proved to be whole plant of Asarum sieboldii and A. sieboldii var. seoulensis.

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Physico-Chemical Identification of Botanical Drugs (생약(한약재(漢藥材))의 규격제정 연구 -TLC를 이용한 정성적 검출법-)

  • Chi, Hyung-Joon;Won, Do-Hi
    • Korean Journal of Pharmacognosy
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    • v.3 no.4
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    • pp.199-204
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    • 1972
  • A new physico-chemical method for identifying botanical drugs was investigated. Fifty drugs were chosen from the presently exported botanical drugs and were classified into 12 groups chemotaxonomically. Various extract(either, 50% ethanol and water) of each group were developed with same solvent system by using chromatographic method(TLC) and observed a characteristic pattern of each drugs. This method, therefore, can be applicable to identify each botanical drug out of the combined phyto-preparations.

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Pharmacognostical Studies on the Chinese Crude Drug 'Yong Dam' (한약 "용담(龍膽)"의 생약학적 연구)

  • Whang, Myung-Suk;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.32 no.1
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    • pp.1-5
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    • 2001
  • The Chinese crude drug, 'Yong Dam (龍膽)' which is derived from the root of Gentiana plants of the family Gentianaceae, has been used as remedy for stomachic, intestinal catarrh, convulsion, etc. With regard to the botanical origin of 'Yong Dam', it has been considered to be Gentiana species of Gentianaceae, especially Gentiana scabra, but there has no pharmacognostical confirmation on it. To clarify the botanical origin of 'Yong Dam' from Korea, we studied on the anatomical characteristics of Gentiana species growing wild in Korea i.e. Gentiana scabra var. buergeri, G. uchiyamai, G. triflora, G. axillariflora var. coreana and of 'Yong Dam' from Korea on Korean market. Through our studies, the botanical origin of 'Yong Dam' from Korea was proved to be Gentiana scabra var. buergeri and Gentiana axillariflora var. coreana.

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A Study on Prescription Intention of Botanical Drug in Korean Medicine Doctors (한의사들의 천연물 신약 처방의사에 관한 연구)

  • Kwon, Yong Chan;Bin, Sung Oh;Koo, Jin Suk;Seo, Bu Il
    • The Korea Journal of Herbology
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    • v.30 no.5
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    • pp.7-13
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    • 2015
  • Objectives : The purpose of this study was to examine the prescription intention of Korean medicine doctors on botanical drug.Methods : The subjects in this study were 340 Korean medicine doctors in Korean medical institutions, on whom a survey was conducted from July 1 to August 31, 2014.Results : The factors that affected the prescription decision making of the Korean medicine doctors were drug superiority, level of Interest, Recognition, marketing of sales associates of pharmaceutical companies and satisfaction with information provided by those companies. When the internal consistency of the variables was measured, that was above 0.8.Conclusions : Accordingly, well-planned education and promotion efforts are required to encourage Korean medicine doctors to put more prescription intention in botanical drug. This study had some limitations : First, the subjects were selected in a manner to allow for the convenience of this researcher, and the findings might not be generalizable. Second, there was a problem with the time for the study in that there were quite fierce disputes on botanical drug at that time. Third, the majority of the subjects run their own hospitals, and the number of them was small. So it's not possible for them to represent every Korean medicine doctor.

Pharmacognostical Studies on the Chinese Crude Drug 'BaegMi' (한약 백미의 생약학적 연구)

  • Ahn, Mi-Jeong;Bae, Ji-Yeong;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.42 no.2
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    • pp.107-109
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    • 2011
  • 'BaegMi(白薇)' is one of the Chinese crude drugs used mainly as an antipyretic and diuretic. The botanical origin of the crude drug has never been studied pharmacognostically. To clarify the botanical origin of BaegMi, the morphological and anatomical characteristics of Cynanchum species growing in Korea were studied. As a result, BaegMi was proved to be the root of Cynanchum atratum and Cynanchum ascyrifolium.

Pharmacognostical Studies on the Chinese Crude Drug 'Man Sam' (한약 만삼의 생약학적 연구)

  • Kueon, Seong-Jae;Oh, Jong-Yung;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.36 no.1
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    • pp.21-25
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    • 2005
  • The Chinese crude drug, 'Man Sam(蔓蔘)', which is derived from the root of Codonopsis plants of the family Campanulaceae, has been used as a tonic. In China, the same crude drug derived from Codonopsis plants, called 'Dang Same(?蔘)', has been used as remedies for anorexia, fatigue, cough, etc. Although Codonopsis roots have been widely used for medicinal purposes in Korea, the botanical origin of the crude drug has never been studied pharmcognostically. To clarify the botanical origin of 'Man Sam', the root morphology and anatomy were examined for the Korean species of Codonopsis species, such as C. lanceolata (Sieb. et Zucc.) Trautv., C. pilosula (Franch.) Nannf. and C. ussuriensis (Rupr. et Maxim.) Hemsl. The study shows that 'Man Sam' is the root of Codonopsis pilosula.

Pharmacognostic evaluation of the roots of Berberis lycium royle

  • Srivastava, Sharad Kumar;Rawat, Ajay Kumar Singh;Mehrotra, Shanta
    • Advances in Traditional Medicine
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    • v.10 no.3
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    • pp.184-190
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    • 2010
  • Berberis lycium (family Berberidaceae) has a close affinity with B. aristata, used in India Traditional Systems of Medicine as a drug 'Daruharidra' for skin disease, jaundice, affection of eyes, and rheumatism. Various species of Berberis are being sold in India herbal drug market. During the market surveillance of different herbal drug markets of India, it was observed that almost all the markets either comprise of Berberis lycium or Berberis asiatica. Keeping this in view, in the present study attempts have been made to identify marker characters of this potent species.

Pharmacognostical Study on the To Bog Ryung (토복령의 생약학적 연구)

  • Park, Jong-Hee;Kim, Jeong-Myo;Do, Weon-Im
    • Korean Journal of Pharmacognosy
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    • v.33 no.3
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    • pp.169-172
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    • 2002
  • Chinese crude drug 'To Bog Ryung' has been to cure chronic aperient, syphilis cough and diabetes. The botanical origin of the crude drug has never been studied pharmacognostically. To clarify the botanical origin of To Bog Ryung, the morphological and anatomical characteristics of the rhizomes of Smilax species growing in Korea, i.e. S. china, S. riparia var. ussuriensis, S. nipponica, S. sieboldii were compared. As a result, it was determined that To Bog Ryung was the rhizome of Smilax china and Smilax sieboldii.

Pharmacognostical Studies on the Chinese Crude Drug ‘Maig Moon Dong’ (한약 "맥문동" 의 생약학적 연구)

  • Geon, Dai-Gun;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.34 no.1
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    • pp.6-9
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    • 2003
  • ‘Maig Moon Dong(麥問冬)’ is one of the chinese crude drugs used mainly to cure a cough and sputum, etc. With regard to the botanical origin of ‘Maig Moon Dong’, it has been considered to be Liriope species of Liliaceae, but there has not been studied pharmacognostically. To clarify the botanical origin of Maig Moon Dong, we studied on the anatomical characteristics of Liriope and Ophiopogon species growing wild in Korea i.e. L. platyphylla, L. spicata, O. jaburan, O. japonicus and Maig Moon Dong from Korea. As a result, the botanical origin of Maig Moon Dong from Korea was proved as Liriope platyphylla and L. spicata.