• Journal of muscle and joint health
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• v.16 no.1
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• pp.5-12
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• 2009

Purpose: The purpose of this study was to investigate bone mineral density(BMD) and fear of falling and falls efficacy in the middle and old aged women over 50 years. Methods: The subjects consisted of 409 women. One-way ANOVA, Pearson's correlations and multiple regression were used to test the BMD, fear of falling and falls efficacy scale by using SPSSWIN 12.0. The BMD of the calcaneus were measured with peripheral dual energy x-ray absorptiometry(DEXA). Results: The average age was 63 years old and the average T-score was -3.21 in patient with osteoporosis, -1.72 with osteopenia, and .13 with normal. There were significant differences in the status of the BMD according to age(p=.000), height(p=.000), weight(p=.000), married status(p=.000), age of menarche(p=.002), and menopause(p=.002). The fear of falling was related with falls efficacy(r=-.247, p=.01), BMD(r=-.337, p=.01). Falls efficacy($\beta$=-.21, p=.000)and BMD($\beta$=-.26, p=.000) were predicting variables of fear of falling. The model explained 13% of the variance in fear of falling(F=27.38, p=.000). Conclusion: Fear of falling and falls efficacy were related with the bone mineral density. Falls efficacy and BMD may be useful for the predicting fear of falling for women in middle and old age. Further studies with assessment of fall-related risk-factors and a longitudinal study are necessary to assess with falls efficacy, and BMD with age.

• Journal of Periodontal and Implant Science
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• v.29 no.4
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• pp.837-846
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• 1999

There were few reports about the fluoride concentration in bone and osteoporotic women. This study was designed to evaluate the relationship between the urinary fluoride concentration and periodontal condition in osteoporotic old women. Twentyeight postmenopausal women(Test group) and twenty-one premenopausal women(Control group) were examined. Bone mineral density(BMD) of lumbar spine(L2-L4) was measured by dual energy X-ray absorptiometry(DEXA). The urine samples were collected at early morning and determined with the help of a fluoride-specific electrode and Tisabbufferd samples. The results were as follows. 1. The mean urinary fluoride concentration in test and control group showed statistically no difference. 2. The bone mineral density(BMD) of the spine in test group was significantly lower than control group(p<0.05). 3. The significant negative correlation was found between BMD level and age after menopause $(p<0.001,\;{\gamma}=-0.526$. 4. The urinary fluoride concentration was not correlated with age, age after menopause and bone mineral density. 5. The urinary fluoride concentration was not correlated with periodontal condition.

• Research in Community and Public Health Nursing
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• v.21 no.3
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• pp.333-340
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• 2010

Purpose: The purpose of this study was to examine the bone mineral density (BMD), body mass index (BMI), stress, and health promotion lifestyle of female college students and to assess relations among them. Methods: A total of 220 female college students were assessed through anthropometric measurements and bone mineral density test using quantitative ultrasound. In addition, the subjects were asked about stress and health promotion lifestyle with a self-rating questionnaire. Collected data were processed with the SPSS/WIN 12.0 program. Results: 1) Of the students, 67.8% had weight control experience. The percentage of the osteoporosis, osteopenia and normal groups were 2.8%, 53.5% and 43.8%, respectively, and the percentage of the underweight, normal and overweight groups according to BMI were 27.9%, 57.2% and 14.9%, respectively. 2) The levels of stress and health promotion lifestyle were 2.9 and 2.3, respectively. 3) There was a positive correlation between BMD and BMI (r=.196, p<.01). There was a negative correlation between stress and health promotion lifestyle (r=-.35, p<.01). 4) Weight control experience made negative effects on BMD and BMI. Conclusion: The findings of this study suggest the necessity of new health promotion programs to increase bone density of female college students. Stress management programs are also needed.

• Journal of Nutrition and Health
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• v.46 no.2
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• pp.147-155
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• 2013

Higher bone mineral density (BMD) at a young age, calcium intake, and exercise are important for prevention of osteoporosis later in life. We examined familial effects of BMD between mothers and children and adolescents aged 8-19 in Cheonan, Korea and the relationships between BMD and lifestyle parameters, including: food and nutrient intake and exercise. For daughters and sons, significant differences in BMD were observed at the three bone sites (total femur, femur neck, and lumbar spine) according to age, gender, body mass index, exercise, and milk consumption, compared to the reference value for each classification category. Mean differences in children's BMD were observed according to maternal BMD. Energy and calcium intake were lower in both children and mothers in comparison to the estimated daily energy requirement; however, their protein intake was much greater than the daily recommended intake. After adjusting for age and gender and for mother's age, body mass index, and total calorie intake, results of the food frequency test showed an association of a higher intake of meat, meat products, milk and milk products with greater BMD of total femur, femur neck, and lumbar spine of children. In addition, exercise was positively associated with higher BMD. Regression analysis showed a positive association of BMD with age, male gender, exercise, and mother's BMD. In conclusion, after adjustment for environmental parameters, maternal BMD had a positive influence on BMD in daughters and sons. This finding suggests that parents need to check their BMD in order to determine whether their children are at increased risk of low BMD.

• Journal of the Korean Dietetic Association
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• v.20 no.3
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• pp.157-173
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• 2014

The main purpose of this study was to investigate factors that affect bone mineral density (BMD) in Korean adult women ($20{\sim}80{\leq}yr$). Data on BMD, anthropometric (height, weight, body mass index, waist circumference, and body fat), and biochemical (total cholesterol, vitamin D, and alkaline phosphatase) measurements were obtained from the Fourth and Fifth Korea National Health and Nutrition Examination Surveys (KNHANES, 2008~2011). Overall, the BMD of subjects had decreased from year to year: the T-scores decreased from 0.657 (2008~2009) to 0.295 (2010~2011) in 40~49 yr group and from 0.076 to -0.081 in 50~59 yr group. Age was negatively associated with BMD (T-scores of 0.388 in 20~29 yr group and -1.952 in ${\geq}80yr$ group for total femoral). BMD continuously increased with increased weight and body mass index (BMI). High values of total cholesterol (T-scores of -0.005 in 201~229 mg/dL group and -0.094 in ${\geq}230mg/dL$ group for total femoral) and alkaline phosphatase (T-scores of 0.481 in ${\geq}102IU/L$ group and -0.674 in ${\geq}336IU/L$ group for total femoral) were associated with lower BMD. Overall height, weight, and BMI were positively associated with BMD, whereas total cholesterol and alkaline phosphatase (ALP) were negatively associated with BMD. Findings of the present study show that bone loss may be associated with various factors such as age, weight, BMI, total cholesterol, and ALP et al., and that much attention should be paid to bone health of adult women. Therefore, practical and systematic programs are required to improve the BMD of adult women as well as to maintain healthy bone levels.

• Biomedical Science Letters
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• v.18 no.3
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• pp.244-253
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• 2012

Bone mineral density (BMD) is used in the clinical diagnosis of osteoporosis and the assessment of fracture risk. Osteoporosis, characterized mainly by decreased BMD, is a highly heritable complex disorder and a major public health concern to hundreds of millions of elderly persons worldwide. However, the specific genetic variants determining risk for low bone density are still largely unknown. Here, we performed association analysis to elucidate the possible relations of genetic polymorphisms in ESR1 gene with low bone density. By examining genotype data of a total of 1813 women in the Korean Association REsource (KARE) study, we discovered the ESR1 gene polymorphisms are associated with decreased BMD and osteoporosis. The results on the BD-RT (bone density estimated by T-score at distal radius), three SNPs (rs2248586, rs9371557, and rs1569788) within the ESR1 gene were significantly associated with bone density. The results on the BD-TT (bone density estimated by T-score at midshaft tibia), five SNPs (rs9371552, rs2248586, rs712221, rs7772475, and rs3798577) were significantly associated with bone density. The SNP rs2248586 within the ESR1 gene had commonly significance in both BD-RT (${\beta}$=-0.151, dominant P=0.049) and BD-TT (${\beta}$=-0.156, dominant P=0.039). In the SNP rs2248586, their ${\beta}$-values in BD-RT and/or BD-TT showed consistent trends with the odds ratios (ORs) of osteoporosis. In summary, we found statistically significant SNPs in ESR1 gene that are associated with both decreased BMD and osteoporosis traits. Therefore, our findings suggest ESR1 gene could be related to pathogenesis of osteoporosis.

• Journal of Korean Foot and Ankle Society
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• v.14 no.2
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• pp.165-168
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• 2010

Purpose: Pain or discomfort caused by foot diseases may lead to abnormal gait, resulting in decreased bone mineral density (BMD) of the affected lower limb. We analyzed the effect of foot affection to BMD and its clinical significance. Materials and Methods: Bilateral hip BMD was evaluated in 93 patients with unilateral chronic foot disease. To minimize statistical errors, we excluded patients with medical histories that had influence on BMD. Analysis was based on the results of BMD tests at the first visit. All patients denied past medical intervention for osteoporosis. The difference in density between bilateral limbs was determined by comparing BMDs of the neck, upper neck, trochanter and total area of hip. Results: Test results revealed the decrease of BMD in the lower limb with the affected foot, compared to the unaffected side. This decrease was significant in the area of the trochanter (p <0.05). There was no marked difference of BMD in relation with duration of affection, underlying disease or age. Pertaining the location of foot affection, the hindfoot group showed significant decrease in BMD compared to the forefoot group. The group with affection in bone and joint also showed a marked decrease in BMD compared to the soft tissue group (p <0.05). Conclusion: Pain and discomfort caused by chronic foot diseases can lead to a decrease in the BMD of the affected lower limb. This may increase the risk of complications such as osteoporotic fracture and muscular atrophy.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.10 no.1
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• pp.30-36
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• 2003

Purpose: The strength of hand grip, low back muscles and knee joint muscles were measured and then compared to the bone mineral density (BMD) of each forearm bones (including ulna and radius), lumbar spine, and femur in young women in order to identify the relationship between muscle strength and bone mineral density. Method: The BMD was measured with a Dual Energy X-ray Absorptiometry and muscle strength was measured with a handgrip dynamometer and a Cybex Norm. Data were analyzed with frequencies, percentages, means, and Pearson correlation coefficients. Result: 1) Higher grip strength correlated positively with higher BMD in the forearm (r=.246, p=.007), higher low back extensor strength with higher BMD in the femur (neck, trochanter and Ward's triangle)($r=.323{\sim}.226$, $p=.003{\sim}.043$) and higher strength in the knee joint extensor with higher BMD in the lumbar spine (r=.227, p=.041), femur neck, and femur trochanter significantly ($r=.295{\sim}.226$, $p=.007{\sim}.043$). There was no significant correlation between the strength of low back extensors and BMD in the lumbar spine, now with strength of knee joint flexor and the BMD in the femur. 2) The muscle strength of each part of the body had significant positive correlations to each other part ($r=.255{\sim}.728$ $p=.021{\sim}.000$) Conclusion: The results of this study showed that with the development of a muscle there was an increased BMD of the corresponding part, and the BMD of each part was influenced by adjacent muscles. To promote the health of bones, it is important to strengthen the muscles of related bones, based on balanced development of all muscles.

• Journal of Nutrition and Health
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• v.25 no.2
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• pp.140-149
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• 1992

It was hypothesized that variations within the range of usual calcium(Ca) and sodium(Na) intakes of Korean influence bone mineral density(BMD) in healthy premenopausal women The relationship of nutrient intake urinary excretion physical activity and circulating IGF-1 level with spine({{{{ { L}_{2 } }}}}-{{{{ { L}_{4 } }}}}) and femur BMD was determined in 47 normal premenpausal women. There was a positive relationship between BMD of the lumbar spine and body weight. The BMD of femoral neck was positively correlated with Ca and protein intakes from animal source and circulating IGF-1 level. There was a negative relationship between femur BMD and both Na intake and urinary excretion. The complex interrelations between femur BMD regression analysis, From this analysis. Ca intake from animal origin was the only significnat Premenopausal women of femur BMD. In the basis of femur BMD three groups were divided Premenopausal women of femur BMD$\leq$0.84g/cm2 showed depressed Ca intake of animal origin in later and early life and enhanced urinary Na excretion compared to women of femur study suggests that dietary Ca is a major constituent affecting femur BMD because of a decrease in net Ca absorption and an increase in urinary Ca loss.

• Journal of Korean Academy of Nursing
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• v.44 no.5
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• pp.504-514
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• 2014

Purpose: This study was done to assess the bone mineral density (BMD), biochemical bone turnover markers (BTMs), and factors associated with bone health in young Korean women. Methods: Participants were 1,298 women, ages 18-29, recruited in Korea. Measurements were BMD by calcaneus quantitative ultrasound, BTMs for Calcium, Phosphorus, Osteocalcin, and C-telopeptide cross-links (CTX), body composition by physical measurements, nutrients by food frequency questionnaire and psychosocial factors associated with bone health by self-report. Results: The mean BMD (Z-score) was -0.94. 8.7% women had lower BMD ($Z-score{\leq}-2$) and 14.3% women had higher BMD ($Z-score{\geq}0$) than women of same age. BTMs were not significantly different between high-BMD ($Z-score{\geq}0$) and low-BMD (Z-score<0) women. However, Osteocalcin and CTX were higher in women preferring caffeine intake, sedentary lifestyle and alcoholic drinks. Body composition and Calcium intake were significantly higher in high-BMD. Low-BMD women reported significantly higher susceptibility and barriers to exercise in health beliefs, lower bone health self-efficacy and promoting behaviors. Conclusion: Results of this study indicate that bone health of young Korean women is not good. Development of diverse strategies to intervene in factors such as exercise, nutrients, self-efficacy, health beliefs and behaviors, shown to be important, are needed to improve bone health.