• Journal of Sensor Science and Technology
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• v.26 no.3
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• pp.160-167
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• 2017

Many stroke patients undergoing rehabilitation therapy require a quantitative indicator for the evaluation of body composition in paretic and non-paretic regions. In this study, the body fluid alteration in the paretic and non-paretic regions of stroke patients with hemiplegia caused by cerebral hemorrhage and cerebral infarction was analyzed using bioelectrical impedance analysis (BIA). Alterations in body fluids were investigated to assess the physical status of the paretic and non-paretic regions of 20 stroke patients with hemiplegia caused by cerebral hemorrhage (7 patients) and cerebral infarction (13 patients). Extracellular water (ECW), intracellular water (ICW), ICW/ECW, total body water (TBW), ECW/TBW, and TBW/fat-free mass were utilized to evaluate the functional status of the paretic and non-paretic regions. Compared with the non-paretic region, the paretic region had high ECW and low ICW. Due to the loss of motor function and nutritional imbalance caused by the stroke, the amount of fat increased while the muscle quantity and quality significantly decreased in the paretic region. Thus, BIA can be a useful tool for quantitatively assessing paretic and non-paretic regions in stroke patients with hemiplegia.

• Economic and Environmental Geology
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• v.25 no.3
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• pp.283-296
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• 1992

The Keumryeong deposits is a low grade copper deposits in which copper minerals form disseminated grains and thin veinlets in felsic volcanics seem to be dacite. Alteration of the volcanics consists mainly pervasive propylitization and silicification. Potassic alteration characterized by biotite developed locally adjacent to southwestern contact of granodiorite body. Principal sulfide minerals in altered zone are mainly pyrite and lesser chalcopyrite. Chalcopyrite content in potassic zone is relatively higher than that of surrounding propylitized zone. Pyrite and chalcopyrite accompanies magnetite, molybdenite, sphalerite, pyrrhotite, arsenopyrite, pentlandite, marcasite, hematite, ilmenite, rutile, bismuthinite and native Bi as disseminations, veinlets and knots. Granodiorite body is propylitized and contains veinlets of pyrite, chalcopyrite and molybdenite. Fluid inclusions in sulfide-bearing quartz veinlets and quartz grains of felsic volcanics and granodiorite in altered zone consist of liquid-rich, vapor-rich, $CO_2-bearing$ and halite-bearing inclusions. These four types of inclusion intimately associated on a microscopic scale and indicate condensing or boiling of ore fluid during mineralization. Homogenization temperature of coexisting fluid inclusions are mostly in the range of 350 to $450^{\circ}C$. High salinity fluid contains 28.6 to 48.4 weight percent NaCI equivalent and moderate salinity fluid cotains 0.5 to 12.5 weight percent NaCl equivalent. Pressure estimated from $CO_2$ mole fraction of $CO_2-bearing$ inclusion range 160 to 375 bars. The Kigu copper deposits is a fissure filling copper vein developed 500 m south from the Keumryong deposits. Mineralogy and fluid inclusion data of the Kigu deposits are similar to that of the Keumryeong deposits. Homogenization temperature of fluid inclusions from the Kigu deposits are reasonable agreement with temperature estimated from sulfidation curve of cubanite-chalcopyrite-pyrite-pyrrhotite and pyrite-pyrrhotite mineral assemblages. Not only mineral occurrence and wall rock alteration in the Keumryeong deposits but also fluid inclusion data such as temperature, salinity, pressure and boiling evidences are similar to those of porphyry copper deposits.

• The Korean Journal of Cytopathology
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• v.19 no.2
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• pp.126-135
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• 2008

Malignant mesothelioma (MM) is a highly lethal neoplasm arising in pleura and the peritoneum and a rapid and accurate diagnosis is crucial for treatment of the disease. However, the sensitivity of cytological analysis using pleural or ascitic fluid is relatively low, yielding an accurate diagnosis in only $32{\sim}79%$ of cases. We tested the diagnostic value of epigenetic alterations in body fluid cytology as a supplement to conventional methods. Paraffin-embedded tissue blocks from 21 MM patients and associated body fluid cytology slides considered no evidence of malignancy were used to test for epigenetic alteration. Using methylation-specific PCR, we detected methylation of RASSF1A and p16 in 47.6% (10/21) of both surgically resected tumor samples, respectively. Body fluid samples of MM also showed abnormal methylation of RASSF1A and p16INK4a genes in 38.1% (8/21) and 33.3% (7/21) of cases. The concordance in the rates of RASSF1A and p16INK4a gene-methylation abnormalities determined from cytology samples and tissue samples were 61.9% (13/21) and 66.7% (14/21), respectively. Combining both genes increases the sensitivity of the test to 57.1 % (12 of 21) of cases. Our results suggest that testing for methylation abnormalities in selected individual genes or gene combinations has diagnostic value as an alternative or adjunct method to conventional cytological diagnosis.

• Economic and Environmental Geology
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• v.54 no.6
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• pp.767-785
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• 2021

World-class magnesite deposits are developed in the Dashiqiao mineralized district of the Jiao-Liao-Ji Belt in China. This belt extends to the northern side of the Korean Peninsula and hosts major magnesite deposits in the Dancheon region of North Korea. Magnesite ores from the Pailou deposits in the Dashiqiao district is classified into pure magnetite, chlorite-magnetite, chlorite-talc-magnetite, and dolomite groups depending on the constituent minerals. According to the result of petrographic study, magnesite was formed by the alteration of dolomite, and, talc, chlorite, and apatite were produced as late-stage alteration minerals that replaced the magnesite. Fluid inclusions observed in magnesite are a liquid-type inclusion, with a homogenization temperature of 121-250 ℃ and a salinity of 1.7-22.4 wt% NaCl equiv. The chlorite geothermometer, indicating the temperature of hydrothermal alteration, is 137~293 ℃, slightly higher than the homogenization temperature of fluid inclusions, and the pressure is calculated to be less than 3.2 kb. For magnesite mineralization in the study area, the initially formed-dolomite was subjected to replacement by Mg-rich fluid to form a magnesite ore body, and then it was enriched through regional metamorphism and hydrothermal alteration. It seems that altered minerals such as talc were crystallized by Si and Al-rich late-stage hydrothermal fluids. These results are similar to the genetic environments of the Daeheung deposit, a representative magnesite deposit in North Korea, and it is believed that the two deposits went through a similar geological and ore genetic process of magnesite mineralization.

• Journal of Korean Academy of Nursing
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• v.25 no.3
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• pp.457-471
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• 1995

This research was done to promote improvement of practical application of nursing diagnoses and to improve the quality of nursing. The subjects of this research were 156 second year students of C junior nursing college who were giving adult patient care. The nursing diagnoses of 312 reports were analyzed using NANDA. In these case reports only nursing diagnoses were considered, of which there were a total of 982. In the data analysis the 9H of the nursing students' nursing diagnoses matched with 105 NANDA nursing diagnoses, Of these, the most frequent diagnoses were pain(165, 17.48%), anxiety(101, 10.70%), alteration in nutrition(83, 8.79%) , sleep disturbance (67, 7.10%), in activity intolerance (67, 7.10%), ineffective breathing pattern(51,5.40%). The etiology for the students' nursing diagnoses were compared with NANDA's nursing diagnoses by frequency. The most frequent etiology for the nursing diagnoses of pain was a biological etiology(50, 31%), for anxiety, situation crisis(58, 57.43%), for alteration in nutrition, indigesion(23, 27.71%), for sleep disturbance, external etiology(25, 37.32%), for activity intolerance, immobile position(22, 32.84%), for ineffective breathing pattern, pain(35, 68.63%), and for ,impaired physical mobility, pain(31, 65.96%). The most frequent etiology for constipation was inadquate digestion of water and cellulose (16, 34.78%), for fluid volume felicity, loss of body fluid (21, 52.50%), for impaired skin integrity, external etilogy(16, 43.24%), for impaired physical mobility, pain(22, 62.86%) , for knowledge deficits, cognition disturbance(9, 27.27％), for ineffective air way clearance, secretion obstruction(14, 48.27%) , for impaired gas exchange, loss of transport ability of blood oxygen(9, 37.50%) , and for powerlessness, therapy environment (5, 22.73%). The number of nursing diagnoses by pattern was exchange(16), moving(6), feeling(4), choosing(4), relating(3), communication(1), perceiving(1), knowing(1), valuing(1).

• Journal of Sensor Science and Technology
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• v.26 no.1
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• pp.15-23
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• 2017

In this study, bioelectrical impedance analysis, which has been used to assess an alteration in intracellular fluid (ICF) of the body, was applied to detect intravenous infiltration. The experimental results are described as follows. Firstly, when infiltration occurred, the resistance gradually decreased with time and frequency i.e., the resistance decreased with increasing time, proportional to the amount of infiltrated intravenous (IV) solution. At each frequency, the resistance gradually decreased with time, indicating the IV solution (also blood) accumulated in the extracellular fluid (ECF) (including interstitial fluid). Secondly, the resistance ratio started to increase at infiltration, showing the highest value after 1.4 min of infiltration, and gradually decreased thereafter. Thirdly, the impedance ($Z_C$) of cell membrane decreased significantly (especially at 50 kHz) during infiltration and gradually decreased thereafter. Fourthly, Cole-Cole plot indicated that the positions of (R, $X_C$) shifted toward left owing to infiltration, reflecting the IV solution accumulated in the ECF. The resistance ($R_0$) at zero frequency decreased continuously over time, indicating that it is a vital impedance parameter capable of detecting early infiltration during IV infusion. Finally, the mechanism of the current flowing through the ECF, cell membrane, and ICF in the subcutaneous tissues was analyzed as a function of time before and after infiltration, using an equivalent circuit model of the human cell. In conclusion, it was confirmed that the infiltration could be detected early using these impedance parameters during the infusion of IV solution.

• Journal of Embryo Transfer
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• v.23 no.1
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• pp.59-64
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• 2008

The objective of this study is to investigate the changes in concentrations of blood urea nitrogen (BUN) and sex steroid hormones, such as estrogen, progesterone, and testosterone in Korean cattle (Hanwoo) with reproductive disorders and to examine the relationship between BUN and body condition score (BCS) in Hanwoo. The concentration of BUN was 16.2 mg/dl, 17.8 mg/dl, 15.1 mg/dl, 17.9 mg/dl, and 28.3mg/dl in pregnancy, repeat breeding, follicular cyst, luteal cyst, and ovarian atrophy, respectively. In Hanwoo with BCS $2.0{\sim}2.9$, $3.0{\sim}3.5$ and $3.6{\sim}4.0$, the concentration of BUN was 15.8 mg/dl, 17.0 mg/dl, and 17.6 mg/dl, respectively. Fluoroimmunoassay showed that serum estrogen and progesterone levels were decreased in reproductive disorders Hanwoo, such as ovarian atrophy, endometritis, and weak estrus. The testosterone level was significantly decreased in Hanwoo with reproductive disorders compared to that in pregnant Hanwoo ($0.02{\sim}0.03\;ng/ml$ vs 0.13 ng/ml, p<0.05). The progesterone and estrogen concentrations in follicular fluid obtained from ovary with follicular cyst were significantly higher (p<0.05) than those in normal follicle fluid. These results show that there is no relationship between BUN and BCS in Hanwoo, and the concentration of sex steroid hormone in serum and follicular fluid are changed in reproductive disorders Hanwoo.

• Journal of the Korean earth science society
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• v.22 no.6
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• pp.548-557
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• 2001

Ultramafic rocks in the Yesan talc ore deposits area are unknown age plutonic rocks which intruded PreCambrian Yoogoo gneiss, and were intruded by Jurassic biotite granite, and Cretaceous acidic and mafic dykes. The ultramafic rocks consist mainly of serpentinite with some amphibolite and talc ore body. The serpentinites are divided 5 rock types (S1${\sim}$S5) on the basis of the developed degree of serpentine phenocrysts and layerings. It seems that the original rocks of the serpentinites were co-magmatic peridotites (dunite and pyroxene peridotite). Main serpentinization from the original rocks was occurred during amphibolite facies regional metamorphism in Choongnam area which Yoogoo gneiss was affected. Main steatitization from the serpentinites was hydrothermal alteration by ascended hydrothermal fluid through crush zones.

• Journal of Embryo Transfer
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• v.23 no.3
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• pp.189-195
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• 2008

The objective of this study is to investigate the changes in concentrations of leptin and insulin in serum of Korean cattle (Hanwoo) with reproductive disorders and to examine the relationship among leptin, insulin, and body condition score (BCS). The concentration of leptin in serum of pregnant Hanwoo showed insignificant difference from that in serum of Hanwoo with reproductive disorder, such as repeat breeding, follicular cyst, corpus luteum cyst, ovarian atrophy, and feeble estrus (p>0.05). However, the concentrations of leptin and insulin in serum were changed with different BCS value. In emaciated Hanwoo (BCS $2.0\sim2.9$), they were significantly decreased compared to BCS $3.0\sim3.4$ (p<0.05). The leptin showed different genotypes with different BCS value. In BCS $2.0\sim2.9$, C/T genotype was expressed (83.3%) more than C/C (16.7%) or T/T (0%) genotype, whereas C/C genotype was expressed (62.5%) more than C/T (25.0%) or T/T (12.5%) genotype in BCS $3.5\sim4.0$. The insulin concentration in follicular fluid obtained from ovary with follicular cyst which has follicles having diameter of $25\sim40 mm$ was significantly higher (p<0.05) than those in normal follicle fluid which has follicles having diameter of $3\sim10 mm$. These results showed that concentration of leptin and insulin in serum were related to BCS value and follicular size and suggest that the changes in concentration of leptin and/or insulin in serum could be a potent biomarker for diagnosis of bovine reproductive disorder.

• Journal of Environmental Health Sciences
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• v.46 no.6
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• pp.667-675
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• 2020

Objectives: Exposure to fine dust (PM10) could contribute to the occurrence of cardiovascular disease or respiratory abnormalities. Since garlic is known to possess an anti-oxidative stress effect, the present study was performed to evaluate the effect of garlic intake on fine dust-mediated pulmonary toxicity. Methods: Rats were intratracheally instilled with fine dust at 15 mg/kg body weight (BW)/day for five days following five-day intragastric intubation of garlic at 0.7 or 1.4 g/kgBW/day, or 13.1 mg/kgBW/day S-allyl-cysteine (SAC) as a reference component in garlic. Blood and bronchoalveolar lavage fluid (BALF) were collected. Results: Deposit of fine dust was visually and histopathologically observed in the lungs. Body weight gain during the instillation period was significantly lowered in all the groups instilled with fine dust. Neutrophil numbers in blood were significantly elevated in the fine dust alone group, but this alteration was diminished in the groups administered with garlic. Levels of serum glutathione were lower in the rats instilled with fine dust alone, and this decrease in the glutathione level seems dose-dependently compensated among the groups administered with garlic. Similar findings were observed in the BALF with statistical significance. Typical pulmonary histopathological observation related with inflammation was demonstrated in the lungs of the rats exposed to fine dust alone, whereas such histopathologic findings were not improved in the groups administered with garlic. Conclusion: The present study suggests that garlic intake could alleviate fine dust-mediated pulmonary or systemic toxicities. Further investigation is necessary to delineate the mechanism of garlic-mediated effects on pulmonary function.