• The Journal of Korean Medicine
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• v.22 no.3
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• pp.74-80
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• 2001

Objectives : Ma-huang is a traditional Chinese medicinal herb, derived from Ephedra sinica Stapf and other Ephedra species, used to treat asthma, nose and lung congestion, and fever with anhidrosis. It contains 0.5-2.5% by weight of total alkaloids, of which ephedrine accounts for 30 to 90%. Recently, Ma-huang has been used as a source of ephedrine in many dietary supplements formulated for the treatment of obesity, since ephedrine has been found to be effective in inducing weight loss in the obese. In this study the effects of the methanol extract of Ma-huang on the adipocyte of epididymal and brown fat pads in rats fed a high fat diet for six weeks were studied. Methods : Male Sprague Dawley rats weighing an average 94g (4 weeks old) were fed either a regular diet (RE) or a high fat diet (HF), and the HF group was subdivided into a Ma-huang methanol extract (30mg/100g body weight) group (HF+MH). The weight of epididymal fat pad and brown adipose tissue were measured. The cell size and cell number per unit area of epididymal fat pad were investigated. Results : The yield weight of methanol extract of Ma-huang was 3.63mg per l00g of Ma-huang. The body weight gain of the HF group was similar with that of the HF+ MH but higher than that of the RE. The weights of the epididymal fat pads and brown adipose tissue of the RE group were lower than those of HF and HF+MH groups. The cell sizes and numbers per unit area of epididymal fat pads of the RE and HF+MH groups were larger than those of HF group. The cell numbers per unit area size of epididymal fat pads were the smallest in the RE group. Conclusions : It could be concluded that the Ma-huang extract has no effect on the epididymal fat pads in rats fed a high fat diet and the clinical application of Ma-huang for the treatment of obesity should be re-considered.

• The Korean Journal of Food And Nutrition
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• v.9 no.1
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• pp.1-11
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• 1996

Male rats of 2 months-old(young), 6 months-old(adult) and 30 months-old(old)were fed 8 or 16 weeks to investigate the e(feats of dietary fat level on the lipid metabolism in the different stages of aging. The response of 30 month old rats to dietary fat level differed from either 2 or 6-months old rats. In 30-months old rats, dietary fat level had a little effect on weight gains, lipid content of serum as compared with other two age groups. Young rats showed higher body weight gain, F.S.R, and PER compared with aged rat. The younger and the more high fat fed the rats were, the more body weight gains, FER and PER showed. Weight of liver and kidney was increased in aged rats but ratio per unit weight of liver and kidney was not affected by age. Serum lipid content was higher in aged rat compared with the young and liver lipid content was higher in high fat diet fed rats. But TG of liver and serum was not changed with aging process. Intake, excretion and absorption of lipid was not changed by age of animals. but absorption was decreased as experimental period was increased.

• Animal Bioscience
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• v.35 no.2
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• pp.247-259
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• 2022

Objective: This study was conducted to investigate the effects of age and diet forms on growth-development patterns, serum metabolism indicators, and parameters of body fat deposition in Cherry Valley ducks. Methods: According to the hatching age and initial weight, a total of 150 1-day-old male SM3 Cherry Valley ducks were randomly assigned to two diet forms (pellet vs powder form). Each treatment had with 5 replicates per treatment and 15 meat ducks per replicate. The study lasted 42 d, which was divided into two periods (1 to 21 vs 22 to 42 d). Results: Our results showed that compared with powder group, ducks in pellet group had greater growth performance during different period (p<0.05). The inflection point was 24 d and was not numerically affected by diet forms. Increasing age (42 vs 21 d) significantly increased the weight of body fat and hepatic fat metabolism related enzyme activities in ducks (p<0.05), meanwhile, increasing age (42 vs 21 d) improved serum metabolism indicators and decreased mRNA expression levels of fat metabolism-related genes in liver (p<0.05). Ducks fed different diets (pellet vs powder form) increased growth performance as well as the weight of body fat and improved serum metabolism indicators (p<0.05). In addition, interactions were found between age and diet forms on the levels of serum metabolism indicators in ducks (p<0.05). Conclusion: In conclusion, powder feed reduced growth performance of ducks, and the day of inflection point was 24 days old. Ducks with higher age or fed with pellet diet showed higher fat deposition. The effect of age and feed forms on body fat deposition might result from changes in the contents of serum metabolism indicators, key enzyme activity of lipid production, and hepatic gene expressions.

• Journal of Korean Academy of Nursing
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• v.36 no.8
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• pp.1359-1366
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• 2006

Purpose. This study was done to determine the effects of weight management program using self-efficacy in middle-aged obese women. The study also attempted to measure the effects of the program on the weight efficacy lifestyle, body composition, and depression. Method. The research design of this study was a nonequivalent control group pretest-posttest design. The experimental group consisted of 21 middle-aged obese women and another 21 middle-aged obese women in the control group. The women in the experimental group participated in the weight management program for 12 weeks using self-efficacy. The weight management program using self-efficacy included education on effects of exercise for weight control, aerobic exercise program, muscle training and counseling through the telephone. Results. After 12 weeks of participation in the program, BMI (p <.0001), body fat % (p <.0001), abdominal fat (p <.0001), in the experimental group were significantly decreased compared to the control group. Weight self-efficacy lifestyle (p <.0001) and depression (p =.006) in the experimental group were significantly improved after the program compared to the control group. According to these findings, weight management program self-efficacy for middle-aged obese women could increase weight efficacy lifestyle, and decrease depression, BMI, body fat, and abdominal fat. Conclusion. The result also suggested that the increasing weight efficacy and lifestyle help the obese women to perform and continue exercise. This program could be used in the community such as public health center for weight care and mental health promotion of middle-aged obese women.

• Journal of the Ergonomics Society of Korea
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• v.13 no.1
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• pp.47-58
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• 1994

The purpose of this study was to obtain the basic data for a design for comfort wear. The subjects of this study were 197 women's university stu- dents. The characteristics of their body types and the thickness of subcuta- neous fat at eight body sites were measured. The thickness of subcutaneous fat was measured by both Ultrasonics and with a Skinfold Caliper. The cor- relation between their values and the thickness of subcutaneous fat were compared. The relationship between Rohrer Index and the subject's self- conception of their body was also compared. The results were as follows: 1. The measurement of thickness of subcutaneous fat at triceps and scapula was a little lower, in using Skinfold Caliper method, than Ultrasonics method because of the pressure of the caliper. 2. Correlation between percentage of fat in body and body characteristics was high in order of chest girth > weight > abdomen girth. 3. The thickness of subcutaneous 8 body these sites was high in order of thigh > triceps > scapula > abdomen > suprailiac > chest > calf > forearm. Percentage of body fat has a positive correlation with both average thickness of subcutaneous fat and thickness of subcutaneous fat at triceps. 4. Rohrer Index shows a positive correlation between average thickness of subcutaneous fat and percentage of body fat. 5. About half of subjects of this study thought that they were obese although the data proved otherwise.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.1
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• pp.105-112
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• 2003

This experimental study was designed to investigate the effects of Seunggijoui-tang on the weight of obese rats induced by high fat diet. A series of experiments have been conducted in order to measure the effects of above the body weight, serum and fat cell. The measurements have been performed on; (1) the increasing amount of body weight; (2) the quantity of total cholesterol, triglyceride, free fatty acid, total lipid, phospholipid, HDL-cholesterol and LDL-cholesterol in serum; (3) the size of the epididymal fat cell and the fat drops area in hepatic lobule. In the SG I (Group fed high fat diet and administered 42.5mg/100g extract of Seunggijoui-tang during 8 weeks), the weight decreased significantly throughout the whole research period. In the SG I & SG II (Group fed high fat diet and administered 85mg/100g extract of Seunggijoui-tang during 8 weeks), the serum total cholesterol, triglyceride, total lipid, phospholipid, LDL-cholesterol decreased significantly in comparison with control group. In the SG I, the serum free fatty acid decreased significantly in comparison with control group. In the SG I & SG II, the serum HDL-cholesterol decreased in comparison with control group, but this result showed no efficacy. In the SG I, the epididymal fat cell decreased significantly in comparison with control group. In the SG II, the fat drops area in hepatic lobule of rats decreased significantly in comparison with control group. Based on the above result, it is assumed that the clinical application of Seunggijoui-tang can help the treatment of obesity.

• Journal of Korean Medicine Rehabilitation
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• v.15 no.1
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• pp.109-126
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• 2005

Objectives : This study is to examine the influence of exorcise program to body shape and body composition of women. Exercise program is composed muscular resistance exercise and aerobic exorcise with 70min/time, 5day/week for 4weeks and designed for the reinforcement of muscular strength and the decease the decrease of obesity. Methods : The subjects of this study are 26 females who are from twenty until thirty-nine years old and are divided into two groups according to Obese Rate. normal weight group is 18 females under a BMI of 23 and overweight group is 8 females over a BMI of 23. we measured body compositon and body shape with body composition analyzer(inbody 3.0) measured body compositions are body weight, Lean body mass, base metabolic rate, body fat, %body fat, waist hip ratio, body mass index. measured 6body shade are upper arm circumference, chest circumference, waist circumference, hip circumference, thigh circumference. the measurements had been taken before exercise of each group, after 4 weeks, after 8 weeks, after 12 weeks. Body compositon and body shape of the measured data were analyzed by two-way repeated ANOVA followed by Dunnett's Post hoc test using SPSS. Differences were considered significant at p<0.05. Results and Conclusions : The weight was reduced at a significant level in overweight group after 4 weeks. Body fat percent was reduced at a significant level in normal group alter 4 weeks and overweight group after 8 weeks. Waist-hip ratio was reduced at a significant level in normal and overweight group after 4 weeks. Lean body mass and body metabolic rate were reduced but did not satisfy statistical significance. Circumference of all body parts showed an decrease after 12 weeks exercise program. Upper Arm, Chest, Waist, Hip Circumference were reduced at a significant level in overweight group after 4 weeks, but In normal group only Waist Circumference was reduced at a significant level after 4 weeks. Aerobic and Circuit weight training for 12 weeks reduced body weight and body fat percent, waist circumstance statistically significant without loss of lean body mass and body metabolic rate. Also these change was more effective in overweight group than in normal group.

• Journal of Nutrition and Health
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• v.38 no.8
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• pp.637-648
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• 2005

This study was performed to investigate the effect of feeding garcinia cambogia extract (HCA) and/or L-carnitine and exercise (swimming) on body weight in rats. Forty-eight male rats (Charles River CD (SD) IGS) of eight weeks old and weighing $323.5\pm2.4g$ were raised for two months with high fat diet ($40\%$ fat as calorie) to induce obesity. After induction of obesity, rats weighing $552.8\pm5.8g$ were blocked into eight groups according to body weight and raised for six weeks with diet containing HCA and/or L-carnitine. Plasma aspartate aminotransferase, alanine aminotransferase, total protein and albumin levels were in normal ranges. Food and calorie intakes of H + C and H + C/H groups were highest among non-exercise (m) groups and exercise (I) groups. Food and calorie intakes of m groups were higher than those of I groups. E groups showed significantly lower body weight gain and calorie efficiency ratio than m groups and H/E group was the lowest among all groups. Perirenal fat pad weights of E groups were lower than m groups, and epididymal fat pad weights of H and H + C groups were lower than CO and C groups among m groups regardless of exercise treatment. Brown adipose tissue weights of I groups were higher than fn groups and highest in H/E group among all groups. Liver citrate lyase activities of H and C groups were lower than CO and H + C groups regardless of exercise treatment. The differences between NE groups and E groups were not found to be significantly. Liver carnitine acyltranferase activity was not significantly different among all groups. Fecal total lipid, triglyceride and total cholesterol excretions were found to be higher in H and H + C uoups compared to CO and C groups both in NE and E animals, those of lipid excretions of NE groups were higher than E groups. In conclusion, HCA was more effective in reduction of body weight and body fat than L-carnitine or HCA + L-carnitine. HCA ingestion with exercise was far more effective than without exercise treatment in reducing body weight and body fat.

• Journal of Korean Medicine Rehabilitation
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• v.26 no.2
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• pp.13-28
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• 2016

Objectives To investigate anti-obesity effects of Galgeun-tang, an herbal formula, in high fat diet induced obese mice model. Methods 24 Male C57Bl/6J mice were randomly assigned to normal group fed with normal research diet (NOR, n=6), high fat diet control group treated with water (HFD, n=6), high fat diet group treated with Orlistat (ORL, n=6, Orlistat 10 mg/kg), and high fat diet group treated with Galgeun-tang (GGT, n=6, Galgeun-tang 700 mg/kg). 12 weeks later, body weight, fat weight, liver weight, blood glucose, total cholesterol, triglyceride, HDL, ALT, AST, obesity related neuropeptides and adipokines, ratio of gut microbiota, and histopathology of liver were evaluated. Results In the GGT group, 1. body weight gain, liver weight gain, and total fat weight gain were significantly less than those in the HFD group. 2. blood glucose level was significantly lower and insulin level was significantly higher than in the HFD group. 3. total cholesterol level and triglyceride (TG) level were significantly lower and high density lipoprotein (HDL) level was significantly higher than in the HFD group. 4. appetite-promoting ARC neuropeptides such as Agrp and Npy were significantly less and appetite-inhibiting ARC neuropeptide, Cart was significantly more than in the HFD group in qRT-PCR analysis. 5. adiponectin level and visfatin level were significantly higher, and resistin level and leptin level was significantly lower than in the HFD group. 6. the relative level of Bacteroidetes was significantly higher, and the relative level of Firmicutes was significantly lower than in the HFD group. 7. the increase of adipose tissue was significantly more inhibited than in the HFD group. Conclusions The present study showed that Glageun-tang exerts anti-obesity effects in that it. 1. inhibited the increase in body weight, liver weight, and total fat weight. 2. decreased the level of TG, and increased the level of HDL. 3. influenced neuropeptides and adipokines that are important in regulating food intake and changes of body weight. 4. modified the beneficial quantitative changes in gut microbiota suppressing the tendency toward obesity.

• Women's Health Nursing
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• v.3 no.2
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• pp.192-207
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• 1997

This study aims at examining relationships between perceived body shape, body image and health complaints among 88 women registered at a facility for managing body shape, which leads to adequate management of obesity in women for healthy lives. The survey was conducted by using a questionnaire consisted of 12 items of general characteristics and interests for weight control, 47 items of body image, and 57 items of Cornell Medical Index(CMI). The data were analyzed by using mean standard deviation, ANOVA, and Pearson correlation coefficient. The results are following. 1. The means of age, body weight, height of the women were 27.02 years, 56.02 years, 56.03kg, 161.71cm, respectively. The level of obesity by body shape was 47.7% for standard type, 26.2% for slim type, 26.1% for fat type. Those women graduated from high school or higher education institutions were 97.7%. 2. More than 70% of the subjects perceived their weight as overweight, while 26.1% of the women were fat according to the level of obesity. Ninety percent of the subjects were not satisfied with their body shape. 3. Body weight increased most during middle and high school days. The women became interested in weight control through talks with friends(35.2%), influence of mass communication(34.1%), and social custom(22.7%). As to the method of weight control, subject's own judgement(54.5%) revealed highest percentage, whereas only 20% of the subjects adopted prescriptions of experts for weight control or of doctors. Those who had side reactions from weight control were 30.7%. High percentages of the women reported the decrease the amount of eating(54.5%), the increase the amount of exercise(27.3%) as the effective methods of weight control. 4. The score of body image differed significantly by the perceived body shape : the score was highest in the perceived standard type. 5. The level of health complaints did not differ by the perceived body shape. In relation to the level of obesity, physical health complaints were high in the groups of very slim type and of very fat type, while mental health complaints were high in the groups of very slim type and of fat type. 6. Very high correlations were observed between the perceived body shape and body image and between physical health complaints and mental health complaints.