• Journal of Physiology & Pathology in Korean Medicine
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• v.27 no.6
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• pp.832-841
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• 2013

This research, as a basic preliminary study for development of functional health food, is aimed at assessing the body fat reduction effect and for application to human body for such reduction in actual clinical settings by preliminary extraction of 2 types of wild edible greens, Lythrum salicaria L. and Aceriphyllum rossii. Subjects over the age of 19 and less than 60 years old with BMI value range of $23.0kg/m^2{\sim}29.9kg/m^2$ were recruited through screening were divided into experimental group and control group, each with 25 subjects, through randomized allocation. With both patients and evaluators wearing blindfold, the experimental group was orally administered with 4 capsules of 500mg of composite preparation containing the extracts of Lythrum salicaria L. and Aceriphyllum rossii 3 times a day for a period of 8 weeks while the control group was orally administered with 4 capsules of 500mg of placebo (fake food) with the same appearance as the preparation administered to the experimental group 3 times a day for a period of 8 weeks. After having carried out evaluation on physical examinations (body weight, BMI and body fat ratio, etc.), laboratory tests (general blood test, biochemical test of blood and urine test), lipid test, the changes were analyzed. There was no significant change between the 2 groups and within the groups in BMI and body fat ratio, which are the primary effectiveness evaluation at each time. There was no significant difference between the 2 groups in serum lipid and WHR, obesity related KOQOL, KEAT-26 which are the secondary effectiveness evaluations. There was no change between the 2 groups and within the groups in vital sign, CBC, BC and urin test. These results suggest that Lythrum salicaria L. and Aceriphyllum rossii ext. showed no significant reduction in BMI, body fat ratio and serum lipid. Additional confirmative clinical application test is needed in the future.

• The Journal of Pediatrics of Korean Medicine
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• v.15 no.1
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• pp.183-194
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• 2001

Purpose : This Study was conducted to find out whether Gwakhyangjunggi-san gamibang has effects on obesity. Method : Before and after medication, we measured height, weight, Bioelectrical Impedance and calculate BMI, and obesity index from 9 obese children who participated in '2001 the 2nd Hur-jun children contest' sponsored by Kyunghee Oriental Medical Center and compared them. Results and Conclusions : 1) After medication, there was reduction of weight, but it has no statistical significance. 2) After medication, there was statistical significant reduction of BMI, obesity index. 3) After medication, there was statistical significant reduction of total fat weight and the percentage of body fat, and significant increase of muscle mass. As above statement, Gwakhyangjunggi-san gamibang has effects on obesity with significant and it is considered that additional and complement study is needed.

• Journal of Korean Medicine for Obesity Research
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• v.21 no.1
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• pp.22-31
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• 2021

Objectives: We conducted a retrospective chart review to investigate the effects of Korean Medicine (KM) treatment on weight loss in patients with morbid obesity (body mass index [BMI]≥30 kg/m²) and to compare the effects of KM counseling and non-counseling on weight loss. Methods: We performed a retrospective chart review of patients with morbid obesity who received KM treatment for at least 1 month. We evaluated the effects of KM treatment on body weight, BMI, body fat, fat mass, EuroQol-5D, and the Korean version of the obesity-related quality of life scale (KOQOL). We also assessed the liver and kidney functions, and adverse events. We performed a comparative analysis between the counseling and non-counseling groups. Results: A total of 37 patients who underwent 4 weeks of KM treatment involving Wolbi-tang, electroacupuncture, and KM counseling were included in this study. Twenty-one patients were assigned to the counseling group and sixteen patients to the non-counseling group. There was a significant decrease in weight, BMI, fat mass, and KOQOL (P<0.05) with improvements in total cholesterol, low-density lipoprotein, and triglycerides. The counseling group had a greater reduction in body weight, BMI, body fat, and fat mass compared to the non-counseling group, although it was not significant. In the BMI below 35 (n=25), the reduction ratio of body weight, body fat mass, and body fat was higher in the counseling group than in the non-counseling group; additionally, body fat decreased significantly in counseling group (P<0.05). No severe adverse effects were observed. Conclusion: KM treatment could be effective for weight loss, especially in patients with morbid obesity, KM counseling could also be a good tool for weight loss, typically in patients with BMI<35 kg/m².

• Journal of Korean Medicine for Obesity Research
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• v.5 no.1
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• pp.47-56
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• 2005

Objectives : This study was performed to investigate the change of bone mineral density(BMD) after 1 month Kirindiet therapy including very low calory diet(VLCD) in middle-aged obese women$(65>age{\geqq}40,\;BMI{\geqq}25)$ under normal $BMD(T-score{\leqq}0)$. Methods : We examined body weight, body fat, protein mass and BMD of 13 middle-aged obese women who visited to Kirin Oriental Hospital from Sep. 7. 2004 to Oct. 12. 2005 before and after 1 month Kirindiet therapy. Body weight, body fat and protein mass was checked by Inbody 4.0 and BMD was checked by quantitated computed tomography. Wilcoxon signed rank test was used for analyzing changes of body weight, body fat, protein mass and BMD before and after treatment. Results : Alter 1 month treatment body weight(-4.89Kg, -6.74%, p=0.001), body fat(-3.47Kg, p=0.001) and protein mass(-0.97Kg, p=0.006) was significantly reduced. BMD was significantly increased in all cases(+4.87mg/cc, +4.16%, p=0.001). Though body weight, body fat and protein mass were significantly reduced, BMD was significantly increased(p<0.01). Conclusions : In this study, we can conclude that after 1 month Kirindiet therapy including VLCD, BMD in middle-aged obese women under normal BMD was significantly increased inspite of reduction of body weight, body fat and protein mass.

• Preventive Nutrition and Food Science
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• v.17 no.3
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• pp.223-227
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• 2012

This study examined the effects of corn gluten (CG), wheat gluten (WG), and soybean protein isolate (SPI), as well as their hydrolysates, on weight reduction in rats fed a high-fat diet. Eight-month-old male Sprague-Dawley rats (n=70) were fed a high-fat diet (40% of the calories were fat) for 4 weeks. Rats were then randomly divided into seven groups and were fed isocaloric diets with different protein sources for 8 weeks. The protein sources were casein (control group), intact CG (CG group), CG hydrolysate (CGH group), intact WG (WG group), WG hydrolysate (WGH group), intact SPI (SPI group), and SPI hydrolysate (SPIH group). Body weight gain, adipose tissue weights, lipid profiles in plasma and liver; and hepatic activities of carnitine palmitoyl transferase, fatty acid synthase (FAS), malic enzyme, and glucose-6-phosphate dehydrogenase were assessed. The CGH group showed significant weight reduction compared with the other groups. Epididymal fat pad and plasma triglycerides in the CGH group were the lowest and were significantly different than those in the control group. FAS activity in the CGH group was significantly lower than that in the other groups. In conclusion, the CGH diet of these experimental animals demonstrated a weight-reducing effect by lowering the adipose tissue weight and by affecting the activities of hepatic lipogenic enzymes.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.2
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• pp.140-150
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• 2009

Purpose: We investigated the efficacy of electroacupuncture therapy in obese Korean women in order to make basic guidelines for the use of oriental medicine in treating obesity. Methods: Forty women were divided into two groups and each was treated 12 times: 1) one group was treated using electroacupuncture (EA) involving auricular acupuncture and physical treatment, without exercise (EA group, n=10), and 2) the other group was treated using electroacupuncture and exercise (EA plus exercise group, n=30). The EA was applied to subcutaneous fat tissue manually. Body weight was evaluated every visit and body composition was checked at the $1^{st}$ and $12^{th}$ visits. Statistical comparisons were made using SPSS13.0. We compared the weight loss, body mass index (BMI), and body composition before and after treatment using the pairedt-test. The correlations between weight loss and BMI and age were examined. Results: After the $12^{th}$ treatment, both groups showed significant reductions in body weight, BMI, body fat, and body fat percentage. The weight loss averaged 4.58${\pm}$3.87% in the EA group and 4.69${\pm}$3.10% in the EA plus Exercise group. The reduction in skeletal muscle was significant in the EA group, but not significant in the EA plus Exercise group. The speed of the weight loss was correlated with age using Pearson's correlation coefficient. Based on BMI, normal and obese subjects in the EA plus Exercise group had significant reductions in body weight, BMI, body fat, and body fat percentage; the obese subjects also had a significant reduction in skeletal muscle. Conclusion: Combined EA therapy may be effective for weight reduction. Age and BMI were related to weight loss using EA therapy.

• Journal of the Korean Applied Science and Technology
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• v.38 no.2
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• pp.453-464
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• 2021

Abdominal obesity is increasing due to a decrease in physical activity and westernization of diet in busy daily life. Therefore, in order to satisfy the desire for body shape management, a management program with high efficiency versus time is needed. In this study, the diet-gel (i.e., slimming cosmetics) with the electrical muscle stimulation therapy was used to promote the effect of reducing waist circumference and body fat mass (or abdominal fat). For men and women in their twenties, the subjects simply applied diet-gel to their waist, wore EMS, and massaged for 20 minutes twice a day after waking up and before going to sleep. The experiment period was carried out for 2 weeks. The reduction of subcutaneous fat was observed using non-contrast CT, and it was confirmed by measuring waist circumference and body fat mass. In conclusion, the developed EMS and diet-gel combination program showed excellent waist management effects by reducing waist circumference by about 3 cm (p<0.001) and body fat mass by about 1 kg (p<0.01). This result suggests that the use of EMS shows a massage effect by muscle stimulation, and plays a role in promoting fat decomposition by helping the absorption of diet gel.

• Journal of Nutrition and Health
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• v.41 no.7
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• pp.634-664
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• 2008

This study investigated the effects of the nutrition education on body weight, visceral fat and diet quality in the postmenopausal women. The subjects (n = 101) were randomly divided into two groups: Nutrition education + Exercise (NEE) group (n = 51) and Exercise only (EO) group (n = 50). Nutrition education was consisted of counseling in portion control, food selection for low carbohydrate, high fiber food items and for the improvement in micronutrient intakes and diet quality. After 6 months, the reduction in the body weight and visceral fat area was significantly greater in the NEE than in the EO group. The NEE subjects were further divided into two groups according to the amount of visceral fat area reduction; high visceral fat area loss (HVL) group with a visceral fat area reduction 2.35% or greater and low visceral fat area loss (LVL) group with a reduction less than 2.35%. In the HVL group, the reduction in body weight, BMI, percent body fat, waist to hip ratio and visceral fat area was significantly greater than that in the LVL group. We observed a significant increase in the serum HDL-cholesterol level and a decrease in systolic blood pressure, fasting blood sucrose, total and LDL-cholesterol levels in the HVL group compared to the LVL group. The energyadjusted protein, fiber, calcium, vitamin $B_6$, vitamin C, vitamin E intakes were significantly increased in the HVL compared to LVL group. The index of nutritional quality (INQ) and mean adequacy ratio (MAR) were also increased in the HVL group compared to the LVL group. These results show that our nutrition education program was an effective intervention measure for the reduction of body weight and visceral fat, blood pressure, glucose and lipid levels in the blood and also for the improvement of nutrient intake and diet quality in postmenopausal women who are overweight.

• Journal of Korean Medicine for Obesity Research
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• v.2 no.1
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• pp.13-23
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• 2002

Background & Methods: In order to study the effect of electro-lipolysis-acupuncture, 57 outpatients who have had herbal medication in Kirin Oriental Hospital were devided to two groups; acupuncture-treated group(46) vs non-acupuncture-treated group(11) Acupuncture-treated group was given electro-lipolysis-acupuncture at least two times a week and administered with herbal diet medication, whereas non-acupuncture-treated group was administered only with herbal diet medication. Results: Mean age, body weight and BMI of these two group at the start point of the treatment were $27.22({\pm}7.64)\;vs \;29.09({\pm}8.73),\;67.76({\pm}9.34)\;vs\;67.00({\pm}10.69),\;and\;26.20({\pm}3.02)\;vs\;26.14({\pm}4.10)$ in the order of acupuncture-treated and non-acupuncture groups. After one month of treatment, change rate of body weight, BMI, total fat, percentage of fat was significantly higher in acupuncture-treated group. Also the change rate of arm circumference, hip circumference and thigh circumference was significantly higher in acupuncture-treated group. The change rate of abdominal circumference and WHR of acupuncture-treated group was higher than that of non-acupuncture-treated group with no statistical significance. The circumference reduction rate according to herbal dieting program was higher in this order, abdomen, arms, chest, thighs and hips. On the other hand, chest circumference change rate over weight loss rate, which is the portion no acupuncture treatment was given to, and AMC change rate was higher in non-acupuncture-treated group. Conclusion: These results imply that herbal dieting program combined with electro-lipolysis-acupuncture is more effective on reducing body fat, size reduction of localized obesity and preservation of muscle than herbal prescription only dieting program.

• Journal of Nutrition and Health
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• v.26 no.1
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• pp.47-55
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• 1993

To investigate the effects of exercise-training on serum lipids, fat distribution and several parameters of body fatness(percent body fat, skinfolds thickness, body circumference) were assessed in 24 healthy male subjects submitted to an 8-wk high intensive exercise-training. Blood sample was taken twice, per and post exercise-training, Exercise-training took place 5 days a week and daily energy intake and expenditure were observed. The results obtained are summarized as follows: 1) Through exercise-training body weight (changes : 1.1$\pm$1.1kg ; p=0.000) and percent body fat (changes : 2.4$\pm$1.3% ; p=0.000) decreased significantly . 2) Suprailiac was the most reduced site by exercise-training among eight site skinfolds. Central skinfolds were changed more by exercise-training than peripheral skinfolds with reduction of 1.7$\pm$1.7mm and 0.2$\pm$1.9mm. Central site circumferences were reduced more by exercise-training than peripheral site circumferences. 3) Total cholesterol, HDL-cholesterol and LDL-cholesterol were not significantly changed by exercise-training while only triglyceride decreased (changes : 20.7$\pm$44.8mg/dl ; p<0.05). Changes in body weight were grately related to changes in total cholesterol. Changes in deep abdominal adipose tissue were related to changes in triglyceride.