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Effects of the Red Garlic Extract for Anti-Obesity and Hypolipidemic in Obese Rats Induced High Fat Diet (홍마늘 추출물이 고지방식이로 유도된 비만 흰쥐의 항비만 및 지질개선에 미치는 영향)

  • Lee, Soo-Jung;Kim, Ra-Jeong;Ryu, Ji-Hyun;Shin, Jung-Hye;Kang, Min-Jung;Kim, In-Soo;Sung, Nak-Ju
    • Journal of Life Science
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    • v.21 no.2
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    • pp.211-220
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    • 2011
  • This study tested the anti-obesity and hypolipidemic effects of red garlic extract in obese rats induced by a high fat diet over a period of 4 weeks. Red garlic extract of 15 brix was added in 1, 3, 5 and 7% ratios in diets. The obesity index and body fat content significantly decreased in rats fed a diet with over 3% red garlic extract compared to the control group. There was no significant difference in weight of visceral and epididymal fat in rats fed red garlic extract. Total lipid and triglyceride levels in serum were significantly decreased in a dose-dependent manner, and AI and CRF also fell. ALT and AST activities in groups fed red garlic extract were decreased compared to the control group. Total lipid level in liver tissue of the groups fed 5-7% red garlic extract exhibited a significant decrease compared to the control group. Total cholesterol and triglyceride levels in feces were significantly increased in rats fed a diet with over 5% red garlic extract. Lipid peroxide levels were significantly decreased in the groups fed diets with 5-7% red garlic and antioxidant activity in serum was significantly increased in the group fed a diet with 7% red garlic extract compared to the control group. Our results suggest that red garlic extract could have anti-obesity and hypolipidemic effects for suppressing obesity index and decreasing lipid profiles.

Effects of Microbial feed Additive and vitamin-C as an Alternative to Antibiotic on Growth Performances and Carcass Characteristics of Meat Cows (항생제 대체제로서 미생물배양액 및 vitamin-C 급여가 육우의 증체 및 도체형질에 미치는 영향)

  • Nam, In-Sik;Han, Chang-Su;Ahn, Jong-Ho
    • Korean Journal of Organic Agriculture
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    • v.23 no.3
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    • pp.523-534
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    • 2015
  • Twenty four Holstein steers (average body weight $714{\pm}13.60kg$) were used in this experiment to determine the effect of supplementing of microbial culture and coated vitamin-C on growth performances and carcass characteristics in finishing Holstein steers. Holstein steers were randomly assigned to feeding groups of control group (Con, 12 kg of basal diet/head/day), microbial culture group (MC, 12 kg of basal diet + 30 g of microbial culture/head/day) and coated vitamin-C group (CVC, 12 kg of basal diet + 10 g of coated vitamin-C/head/day). MC and CVC groups were higher in ADG compared to control (P<0.05). FCR was also lower in MC and CVC groups than control group (P<0.05). Back fat thickness, rib-eye area, marbling score, meat color and yield index were not changed by supplementing microbial culture and coated vitamin-C. MC group was higher for maturity compared to control and CVC group (P<0.05). CVC group was higher for fat color compared to control and MC group (P<0.05). Based on the results obtained from the current study, supplementation of microbial culture and coated vitamin-C as an alternative to antibiotic might increase growth performances and enhance carcass characteristics in finishing Holstein steers. However, more studies are needed to find out the optimum supplementing period of microbial culture or coated vitamin-C for high quality meat production from Holstein steers.

Development of the New Hybrid Evolutionary Algorithm for Low Vibration of Ship Structures (선박 구조물의 저진동 설계를 위한 새로운 조합 유전 알고리듬 개발)

  • Kong, Young-Mo;Choi, Su-Hyun;Song, Jin-Dae;Yang, Bo-Suk
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.16 no.6 s.111
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    • pp.665-673
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    • 2006
  • This paper proposes a RSM-based hybrid evolutionary Algorithm (RHEA) which combines the merits of the popular programs such as genetic algorithm (GA), tabu search method and response surface methodology (RSM). This algorithm, for improving the convergent speed that is thought to be the demerit of genetic algorithm, uses response surface methodology and simplex method. The mutation of GA offers random variety to finding the optimum solution. In this study, however, systematic variety can be secured through the use of tabu list. Efficiency of this method has been proven by applying traditional left functions and comparing the results to GA. It was also proved that the newly suggested algorithm is very effective to find the global optimum solution to minimize the weight for avoiding the resonance of fresh water tank that is placed in the after body area of ship. According to the study, GA's convergent speed in initial stages is improved by using RSM method. An optimized solution is calculated without the evaluation of additional actual objective function. In a summary, it is concluded that RHEA is a very powerful global optimization algorithm from the view point of convergent speed and global search ability.

Evaluation of the Movement Pattern of Siniperca scherzeri Using the Radio Telemetry in the Middle Part of the Geum-River where Wiers were Constructed Recently (Radio telemetry를 이용한 금강보 설치구간에서 쏘가리(Siniperca scherzeri)의 이동 특성)

  • Baek, Seung-Ho;Yoon, Ju-Duk;Kim, Jeong-Hui;Park, Sang-Hyeon;Lee, Jin-Woong;Jang, Min-Ho;Kim, Su Kyung;Byeon, Myeong-Seop
    • Korean Journal of Ecology and Environment
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    • v.48 no.2
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    • pp.77-85
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    • 2015
  • Siniperca scherzeri is major target species for restocking and restoration project as it is one of the economic species in South Korea. In this study, to investigate their ecological characteristics movement pattern and habitat characteristic of S. scherzeri were analyzed using radio telemetry. Three specimens released during spawning season, moved more than 10 km toward upstream from the release site. Whereas the remains released after spawning season, settled within 400 m of their release site except two specimens (Ss 11, 3.2 km; Ss, 15, 1.4 km). One of possible reason of upstream movement during spawning season is reproduction. The conditions of their settlement area is similar with reference conditions of their spawning ground. S. scherzeri were mainly detected near the edge of the water, and it may related with the facts that rocks are mainly located at the edge of the water and S. scherzeri prefers rocks for their shelter. AMD (Accumulated movement distance) positively related with body weight and condition factor K, but no significant relationship was identified with gender and total length. Daily movement boundary of S. scherzeri was $214.94m^2{\sim}3,257.19m^2$, and their movement was restricted near the edge of the water. The results of this study could be useful to restocking and restoration.

Expanding the Substances of Water Quality Standard for the Protection of Human Health Based on Risk Assessment (인체 위해성기반 수질환경기준 항목 확대를 위한 연구)

  • An, Youn-Joo;Nam, Sun-Hwa;Lee, Jae-Kwan
    • Korean Journal of Ecology and Environment
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    • v.41 no.1
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    • pp.34-42
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    • 2008
  • Water quality standards (WQS) are mandatory to guarantee the human health and protection of aquatic ecosystems, and maintain the condition of suitable water quality. The present WQS for the protection of human health in Korea contain nine substances (As, Cd, $Cr^{6+}$, CN, Pb, Hg, ABS, organophosphorus compounds and PCBs), but it is insufficient to preserve the human and aquatic ecosystem from a variety of chemicals. Therefore, it is necessary to expand the substance of WQS for the protection of human health. In this study, we chose the 20 chemicals from 43 chemicals of the project entitled 'Development of Integrated Methodology for Evaluation of Water Environment'. The methodology for calculating water quality criteria was amended from the US Environmental Protection Agency (US EPA)'s equation for deriving ambient water quality criteria for the protection of human health. The factors including fish intake, drinking water intake, and human body weight used in the equation reflected Korean situations. The monitoring values were derived from the water quality monitoring data in Korean four main rivers. The orders of priorities of chemicals were evaluated by human health risk assessment, and the proposed WQS was derived by technical and economic analyses. These results were reflected to expand the WQS for the protection of human health.

Fish Community and Upstream of Glass Eels (Anguilla japonica) in the Imjin River Estuary, Korea (임진강 하구역의 어류 군집과 실뱀장어 소상)

  • Byeon, Hwa-Keun
    • Korean Journal of Ecology and Environment
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    • v.47 no.spc
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    • pp.31-38
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    • 2014
  • The fish community and upstream of glass eels (Anguilla japonica) in the Imjin River estuary Gyeonggi-do, Korea was investigated from 2008 to 2012. During the surveyed period 43 species belonging to 18 families were collected. Korean endemic species was Microphysogobio jeoni which showed a ration of 0.04% in collected species. Exotic fishes were Carassius cuvieri and Ctenophayngodon idellus, and comprised 0.06% of the total individual number. Among the fish species observed, 17 species of the freshwater fish (40.5%), 6 species of migration fish (14.2%), 8 species of the brackish water fish (19.1%) and 11 species of sea water fish (26.1%). In terms of composition ration, Anguilla japonica (glass eels, 49.8%), Coilia ectens (23.3%), Saurogobio dabryi (8.1%), Repomucenus olidus (3.3%), Lateolabrax maculata (2.9%) and Chelon haematocheilus (2.8%) were found to display high individual number. On the other hand, C. ectens (33.6%), C. haematocheilus (14.2%), Cyprinus carpio (10.5%), Mugil cephalus (9.1%) and S. dabryi (7.6%) were dominated of biomass. The dominant species of individual was A. japonica (glass eels), and subdomint species included C. ectens. The fish biomass catched of fisherman in the Imjin River (Paju-si) were 83.6~240.3 t by each year. The year 2011 and 2012 were decreased rapidly. Among these, M. cephalus (48.0~80.0%), C. carpio (6.7%), Carassius auratus (4.9%), Silurus asotus (3.9%), Takifugu obscurus (2.5%), Anguilla japonica (adult, 2.2%) and Pseudobagrus fulvidraco (2.1%) dominated of biomass. Body weight of glass eels at each year were 0.03~ 1.13 t, average 212.0 kg and 1,325,000 individual by 0.16 g each one individual.

Effect of Feeding a By-product Feeds-based Silage (Biosilage®) on Behavior Pattern of Growing Hanwoo Steers (부산물사료 주원료 사일리지(Biosilage®) 급여가 거세 육성 한우의 행동양식에 미치는 영향)

  • Kim, Young Il;Lee, Sang Moo;Park, Keun Kyu;Kwak, Wan Sup
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.33 no.4
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    • pp.290-297
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    • 2013
  • This study was carried out to investigate the effects of a by-product feed-based silage (BF silage) feeding on behavior patterns of growing Hanwoo steers. A total of 10 Hanwoo steers (11 months old, 302kg of body weight) were assigned to 2 dietary treatments: the control (concentrate mix + free access to rice straw), and the treatment (concentrate mix + free access to BF silage). The behavior patterns were observed for 48 hours. The intakes of dry matter (DM) and neutral detergent fiber (NDF) of the treatment group were higher than those of the control group. Eating time, ruminating time and resting time were not different between the control and treatment. But, the intake time per kg DM was higher for the control than treatment. The number of bolus, total chewing frequency, number of ruminating per bolus and number of bolus per minute were not different between the control and treatment. But the chewing frequency per bolus was higher in the treatment than control (p<0.05), and feed value index was lower in treatment than control (p<0.05). Frequencies of drinking and defecating were not different between the two groups, but the frequency of urinating was higher for the treatment (p<0.05) than control. Eating rate, ruminating efficiency and chewing efficiency were much higher in the treatment group than control (p<0.05). These results indicate that the replacement of conventional rice straws with the BF silage (physically effective NDF, about 25%) did not affect the ruminating behaviors of Hanwoo steers significantly.

Protective Effects of Akebia quinata Fruit Extract on Acute Alcohol-induced Hepatotoxicity in Mice (급성 알코올 간독성을 유발한 생쥐에 있어서 으름 열매 추출물의 간 기능 보호효과)

  • Lee, Sang Hoon;Song, Young Sun;Lee, Seo Yeon;Kim, So Young;Ko, Kwang Suk
    • Korean Journal of Food Science and Technology
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    • v.46 no.5
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    • pp.622-629
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    • 2014
  • We studied the effects of Akebia quinata fruit extract (AQ) on acute alcohol-induced hepatotoxicity in mice. AQ (30-1,000 mg/kg body weight (BW) per day) was orally administered to the study group, once daily for 1 week. On the last day of AQ treatment, ethanol (6 mg/kg BW) was orally administered to induce acute liver injury. The AQ-treated group showed significantly lower levels of alanine aminotransferase and aspartate aminotransferase, compared to the only ethanol-treated group (ETG). The glutathione level in the AQ-treated group elevated up to 20.6%, compared to that observed in the ETG. The mRNA expression of glutathione synthetic enzymes was also higher in the AQ-treated group, compared to the ETG. The AQ-treated group also exhibited lower levels of expression of NADPH oxidase 4 and tumor necrosis factor alpha mRNA. Thus, these results show that AQ treatment can be a potential method to reduce oxidative stress and inflammation in ethanol-treated mouse liver and also that AQ can be a useful therapeutic agent for acute alcohol-induced hepatotoxicity.

Effect of a Soy-Sprout Beverage Prepared with High-Concentrated Oxygen Water on Alcohol Metabolism in Rats (고농도 산소수로 재배한 콩나물 추출 음료의 알코올 분해 효능)

  • Sung, Hea Mi;Jung, Hyun Jung;Yun, Su Kyoung;Kim, Tae Yong;Kim, Ki Myong;Wee, Ji-Hyang
    • Korean Journal of Food Science and Technology
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    • v.46 no.5
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    • pp.616-621
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    • 2014
  • This study was conducted to investigate the detoxification effect of extract from soy-sprout grown using high concentrated oxygen water extract (SE) against alcohol-induced hangover in male Sprague-Dawley (SD) rats. The rats were orally administered with different concentrations of SE beverage [26, 260 and 2,000 mg/kg body weight (b.w.)] and, after 30 min, with alcohol at a dose of 3 g/kg b.w. After 1 and 3 h of alcohol administration, blood was collected from the retro-orbital plexus, while after 5 h, blood was collected from the heart. In the 2,000 mg/kg b.w. SE group, the concentration of blood alcohol was significantly reduced after 1-5 h of alcohol loading as compared with that in the other groups. In addition, the blood acetaldehyde concentration was reduced by SE (2,000 mg/kg b.w.). These results suggest that SE beverage can alleviate alcohol hangover symptoms by stimulating the activities related to hepatic alcohol-metabolizing enzymes.

The effects of $\beta$-1,3/1,6-linked glucan in the diet on immune responses of olive flounder, Paralichthys olivaceus by oral admimistration ($\beta$-1,3 / 1,6-linked glucan 첨가사료가 넙치의 비특이적 면역반응에 미치는 영향)

  • Won, Gyeong-Mi;Kim, Su-Mi;Park, Su-Il
    • Journal of fish pathology
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    • v.17 no.1
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    • pp.29-38
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    • 2004
  • The effects of dietary $\beta$-1,3/1,6-linked glucan administration on nonspecific immune responses, hematology and disease resistance against Edwardsiella tarda in olive flounder, Paralichthys olivaceus were evaluated. Fish were fed the experimental diets supplemented with 0 %, 0.01 %, 0.05 %, 0.1 %, and 0.5 % of $\beta$-glucan to a commercial diet for 7 weeks. The test was performed in two ways such as fed on each $\beta$-glucan concentrations daily and every other week alternately. The body weight gain from the fish fed on daily the 0.05 % supplemented diet and fed on alternately the 0.1 % supplemented diet of $\beta$-glucan were significantly higher than the control. Both lysozyme activity and intracellular superoxide anion production of kidney phagocytes were higher in the all experimental groups than in the control. But there was no large difference in hematology among each group. The relative percent survival rate (RPS) after an artificial challenge with $4{\times}10^6$ cells of E. tarda per fish was higher than the control, except for that fed on daily the 0.01 % supplemented diet.