• Journal of Pharmaceutical Investigation
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• v.20 no.1
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• pp.19-28
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• 1990

Pharmacokinetic parameters of aminoglycosides are dependent on renal function, sex, age, hematocrit, fever, lean body weight (LBW) and disease states, etc. Therefore, the individual pharmacokinetic parameters such as half life $(t^{1/2})$ and volume of distribution(Vd) are needed to achieve optimal therapy. However these parameters had not been determined in Koreans. The purpose of this study was to evaluate the Vd and $t^{1/2}$ of amikacin in Korean patients who had normal renal function, to compare the mean values of study group with that reported in the literature and to compare the measured $t^{1/2}$ with the expected $t^{1/2}$ based on actual body weight (ABW), LBW and ideal body weight (IBW), respectively. Based on data, the Vd was greater than the literature and $t^{1/2}$ was similar to the literature. The predicted $t^{1/2}$ based on IBW was the closest to actual $t^{1/2}$. And postpartum patients had greater Vd than other group and had lower correlation between actual elimination rate constant and calculated creatinine clearance but higher correlation between actual elimination rate constant and Vd than other group.

• Journal of Ocean Engineering and Technology
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• v.31 no.2
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• pp.155-163
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• 2017

Submerged bodies moving underwater behave differently based on their type and assigned mission. This paper describes the dynamic characteristics, including the stability, turning ability, and operational ability, of submerged bodies in relation to design parameters such as the tail cone angle, shape of the control plate, and length of the parallel middle body. A submerged body operated in other countries is adopted as a reference for the dynamic characteristics, its principal dimensions and the shape of the bare hull and appendages are used for comparison. This paper suggests a few candidate hull forms based on changes in the typical design parameters. Finally, the dynamic characteristics for these candidate hull forms are defined.

• Korean Journal of Computational Design and Engineering
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• v.16 no.6
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• pp.424-436
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• 2011

In this paper, we propose a methodology of generating a parametric segment model for human body using the Korean anthropometric data. The model is defined as an articulated body model consisted with 19 ellipsoid primitives. The primitives are joined at locations representing the physical joints of human body. A lot of previous researches have suggested methodologies of generating body models using the European or American anthropometric data, so that these models were inappropriate for engineering analyses and simulations in case of the Koreans. We defined a set of 35 body dimensions representing our segment model based on the anthropometric data of Koreans. Also we defined four key parameters of age, height, weight and waist circumference, and then we applied regression equations to associate the parameters to the aforementioned dimensions. As the results, we obtained the parametric human body segment models according to the various body types and the subject-specific models for a specific individual. The models in the various industries can be used as the base models for static and dynamic analysis considering the Koreans.

• Fashion & Textile Research Journal
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• v.16 no.2
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• pp.266-274
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• 2014

Parametric bodies reproduce the actual shape of human body parts and should be convenient for general users to change size to judge the visual fit of clothes on-line. In this study, three parametric bodies(i.e. I, C, D ) were compared to verify the accuracy of the provided body dimensions and reproducibility to a target model. To compare reproducibility, the 20s female standard virtual model developed for an apparel industry by Korean agency for technology and standards is used. The investigation of existing parameters showed that the numbers and kinds of parameters provided by each program were different with some errors in notation; in addition, some of virtual body dimensions went beyond the maximum allowable error. The result of changing each parametric body to the 20s female standard body showed that D, C, I in order produced better reproducibility for body dimensions. There were different levels of protrusion and concavity in the virtual cross sections and virtual longitudinal sections despite the small differences in body dimensions and cross sectional areas; in addition, some parametric body was not bilateral symmetry. The results of this study can be used as basic information in the standardization of a virtual model used in a virtual garment program.

• Journal of Animal Science and Technology
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• v.54 no.6
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• pp.395-400
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• 2012

This study was conducted to estimate the growth curve parameters for the body weight (BW) and body length (BL) of miniature pigs in Korea. Growth curve parameters were estimated through a nonlinear regression model using Gompertz, Logistic, and von Bertalanffy methods. A total of 25 piglets were measured monthly from birth up to 15 months of age to estimate both body weight and length. Results showed that the estimated average values for the body weight (body length) were 31.83 kg (58.77 cm) for the mature weight (A), 3.06 (1.74) for the growth ratio (${\beta}$), and 0.28 (0.52) for the maturing rate (${\kappa}$). Average inflection points showing maximum growth rate estimated each month for body weight were 3.97 kg and 11.70 cm, while for the body length were 1.06 kg and 21.61 cm. Moreover, the estimated maturation rates of the body weight and length for the group of Sire 1 were 0.22 and 0.40 respectively, whereas for the group of Sire 2 these values were 0.34 and 0.39. On the other hand, for the groups of Dam 1, Dam 2, and Dam 3, maturation rates for their body weights were 0.26, 0.28 and 0.33 respectively, while for their body lengths these values were 0.43, 0.37, and 0.38, respectively. The study also indicated a negative relationship between the values of mature weight and maturity rate for the body weight will result to a higher inflection point which is in contrast for the body length where results show that a positive relationship between the values of mature length and the maturity rate will result to a higher inflection point. Furthermore, the growth performance of miniature pig varies across stages but using these estimated growth curve parameters could improve the genetic traits of miniature pig.

• Advances in aircraft and spacecraft science
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• v.10 no.5
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• pp.419-437
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• 2023

This paper presents the study of the effects of rigid-body motion simultaneously with the presence of the effects of temporal variation due to the existence of morphing speed on the aeroelastic stability of the two-stage telescopic wings, and hence this is the main novelty of this study. To this aim, Euler-Bernoulli beam theory is used to model the bending-torsional dynamics of the wing. The aerodynamic loads on the wing in an incompressible flow regime are determined by using Peters' unsteady aerodynamic model. The governing aeroelastic equations are discretized employing a finite element method based on the beam-rod model. The effects of rigid-body motion on the length-based stability of the wing are determined by checking the eigenvalues of system. The obtained results are compared with those available in the literature, and a good agreement is observed. Furthermore, the effects of different parameters of rigid-body such as the mass, radius of gyration, fuselage center of gravity distance from wing elastic axis on the aeroelastic stability are discussed. It is found that some parameters can cause unpredictable changes in the critical length and frequency. Also, paying attention to the fuselage parameters and how they affect stability is very important and will play a significant role in the design.

• Journal of Ginseng Research
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• v.13 no.1
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• pp.49-55
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• 1989

The change in bodyweight, organ weight and the amount of water intake were investigated to assess the effect on a range of toxicological parameters of varying dosages of polyacetylene compounds. Concerning inhibition of solid tumor growth induced by Sarcoma-180 cells in the ICR mouse strain, relytionships between the dosage of polyacetylene compoilnds used and several toxicological parameters were observed. When 40μmoles/kg b.w. of panaxydol tvas administered for 3 consecutive days, the suppression of body weight growth in Wistar rats was about 17% that of the control group, however, the body weight gain was normalized 4 days after stopping arlnlinistration of the polyacetylene compounds. When the dosage of polyacetylenes was reduced to 20μmoles/kg b.w., the change in body weight gain was alleviated to within l0% of the control and the suppremission of the body weight gain increased in order for Panaxydol, Panaxynol, and Panaxytriol. The organ weight did not show any significant change between the control and the polyacetylene administered groups. Electron micrographs of the liver tissues of ICR mice injected with 40Umoles/kg b.w. of panaxydol gave no further significant information about toxicological changes. Keywords Polyacrtylenes, toxicological parameters, body weight, panaxydol, organ weight, electron micrographs .

• International Journal of Aeronautical and Space Sciences
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• v.11 no.2
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• pp.59-68
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• 2010

The aim of this work is to analyze high temperature flows around an axisymmetric blunt body taking into account chemical and vibrational non-equilibrium state for air mixture species. For this purpose, a finite volume methodology is employed to determine the supersonic flow parameters around the axisymmetric blunt body. This allows the capture of a shock wave before a blunt body placed in supersonic free stream. The numerical technique uses the flux vector splitting method of Van Leer. Here, adequate time stepping parameters, along with Courant, Friedrich, Lewis coefficient and mesh size level are selected to ensure numerical convergence, sought with an order of $10^{-8}$.

• Journal of Korean Medicine Rehabilitation
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• v.19 no.3
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• pp.91-100
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• 2009

Objectives : The purpose of this study was to find the characteristics of Sasang Constitution, Soeumin, Soyangin and Taeumin, Using Regular Medical Inspection. Methods : Subjects of our study were 325 cases who took regular medical inspection. We collected the data of body composition analysis, 7-zone-diagnostic system, blood analysis, and analyzed by Sasang Constitution, Soeumin, Soyangin and Taeumin. Results and Conclusions : 1. In body composition analysis, Taeumin was significantly higher than Soeumin and Soyangin about soft lean mass, body fat mass, waist-hip ratio, body water index, body mass index and basal metabolic rate. In blood analysis, Taeumin was significantly highest about total protein, albumin, GPT, hemoglobin, WBC, triglyceride. In 7-zone-diagnostic system, Taeumin had the highest level at Zone 1, 2. 2. Taeumin had more significant differences than other Sasang constitutions about the parameters of regular medical inspection. 3. Body composition analysis had the most parameters that showed differences among the constitutions, followed by blood analysis and 7-zone-diagnostic system.

• Journal of Hydrospace Technology
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• v.2 no.1
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• pp.1-9
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• 1996

We consider the following two questions mainly in this study. First one is how the free surface hayes affect the lift of a shallowly submerged moving body. For this matte., we reinterpret the theoretical results of Kochin(1936), and point out that the high Froude number approximation is not always on the safer side. Second one is what sort of dimensionless parameters determine the occurrence of wave breaking behind a moving submerged body. Temporarily before getting a better answer, we propose that the two-parameter-plane, namely, the plane of the Froude number and the square root of the ratio of the submerged depth and the body length, may be used for predicting the possibility of wave breaking behind the submerged body. A region in the parameter plane is put forth as that of wave breaking, and the validity of this proposal is shown by its agreement with the existing experimental data of Parkin et al(1955) and those of Duncan(1983). Finally, linear and nonlinear numerical results are compared with the existing experimental data to see in what range of the parameters the linear and nonlinear theory case predict the wave field and the pressure on the body with reasonable accuracy. However, since the experimental data, which offer both the pressure and wave elevation for a submerged moving body, are very scarce, much cannot be attained through this comparative study. Hence, it is strongly recommended to carry out well planned experiments to get such data.